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The map label for this gene is exbB [H]

Identifier: 93005888

GI number: 93005888

Start: 1275935

End: 1276669

Strand: Direct

Name: exbB [H]

Synonym: Pcryo_1060

Alternate gene names: 93005888

Gene position: 1275935-1276669 (Clockwise)

Preceding gene: 93005887

Following gene: 93005889

Centisome position: 41.7

GC content: 43.81

Gene sequence:

>735_bases
ATGTGGGAGTTGGTAAAAGCGGGTGGTTGGCTGATGACACCTATTGTGTTGTGCTCTATTTTAGCATTGGTGATTATTAT
TGAGCGTAGCCATACCTTACAGTTTAACAAGGTTGCCCCAAATAGATTGCGTGAGCAGCTGATTACTCGCCTCCGTGAAA
ATGGTGACATTGGTCGTACGCAGCTAATGAATGTCAAAGAAAAGACTGCGTTAGGTGATATCCTAGCAACGGGTTTGCTC
TATCGTCAATACGGCTTAGAGTCGATGACGATGCATATGCAAAATCGTGCAAGCGTACAAGTCCATCAGTTAGAAAAAAA
TATCAATATGCTTGGTACTATCGGAGCGATTGCCCCTTTACTTGGCCTGTTAGGTACAGTACTGGGTATTATCTCATCGT
TCTTAGCGATTACTGATGGTGCGATGCAAGACCCAACAATGCTTGCTGCAGGGGTGTCGCAAGCTCTGATTACGACTGCG
GCTGGCATGATAGTTGCCATCCCAGCGTTGGTAGCCTATCGCTATTTTCAGCGCCGTATCATCGATATCAATGCGCAATT
TGAAACCCAAGCAGGATTGATGGTTCAAGAGTTATACGATTATCAACTGTTAGAAAACACCCATATTCCTAATACATCTA
AGCAAGTTACTCATGCTGCAGTAGATGATAGCATAAGAGATCAGCACTCAATTGACAGATTTGGTTTAGATGAAACGGCA
ACGGCTACTCTATAG

Upstream 100 bases:

>100_bases
GGAAGCACAGGCTTAAAATATTGCGTGTGTATTTAATCTAATGCTTATTTAAATAGTCTTGATGACCGCTATTTTTATCA
AAATATAGAAGAGAGTTGAT

Downstream 100 bases:

>100_bases
TTGTGTTTTTAGCAGCTCCATCGTGGCATTGTGAAAACGCTATATTGGTCAGATTAGTATCGAATATCACGACTATTGAA
GAGAGTGACATGCGCTTTAG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MWELVKAGGWLMTPIVLCSILALVIIIERSHTLQFNKVAPNRLREQLITRLRENGDIGRTQLMNVKEKTALGDILATGLL
YRQYGLESMTMHMQNRASVQVHQLEKNINMLGTIGAIAPLLGLLGTVLGIISSFLAITDGAMQDPTMLAAGVSQALITTA
AGMIVAIPALVAYRYFQRRIIDINAQFETQAGLMVQELYDYQLLENTHIPNTSKQVTHAAVDDSIRDQHSIDRFGLDETA
TATL

Sequences:

>Translated_244_residues
MWELVKAGGWLMTPIVLCSILALVIIIERSHTLQFNKVAPNRLREQLITRLRENGDIGRTQLMNVKEKTALGDILATGLL
YRQYGLESMTMHMQNRASVQVHQLEKNINMLGTIGAIAPLLGLLGTVLGIISSFLAITDGAMQDPTMLAAGVSQALITTA
AGMIVAIPALVAYRYFQRRIIDINAQFETQAGLMVQELYDYQLLENTHIPNTSKQVTHAAVDDSIRDQHSIDRFGLDETA
TATL
>Mature_244_residues
MWELVKAGGWLMTPIVLCSILALVIIIERSHTLQFNKVAPNRLREQLITRLRENGDIGRTQLMNVKEKTALGDILATGLL
YRQYGLESMTMHMQNRASVQVHQLEKNINMLGTIGAIAPLLGLLGTVLGIISSFLAITDGAMQDPTMLAAGVSQALITTA
AGMIVAIPALVAYRYFQRRIIDINAQFETQAGLMVQELYDYQLLENTHIPNTSKQVTHAAVDDSIRDQHSIDRFGLDETA
TATL

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=94, Percent_Identity=38.2978723404255, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786958, Length=106, Percent_Identity=36.7924528301887, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26915; Mature: 26915

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWELVKAGGWLMTPIVLCSILALVIIIERSHTLQFNKVAPNRLREQLITRLRENGDIGRT
CCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHH
QLMNVKEKTALGDILATGLLYRQYGLESMTMHMQNRASVQVHQLEKNINMLGTIGAIAPL
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGLLGTVLGIISSFLAITDGAMQDPTMLAAGVSQALITTAAGMIVAIPALVAYRYFQRRI
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDINAQFETQAGLMVQELYDYQLLENTHIPNTSKQVTHAAVDDSIRDQHSIDRFGLDETA
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TATL
HCCC
>Mature Secondary Structure
MWELVKAGGWLMTPIVLCSILALVIIIERSHTLQFNKVAPNRLREQLITRLRENGDIGRT
CCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHH
QLMNVKEKTALGDILATGLLYRQYGLESMTMHMQNRASVQVHQLEKNINMLGTIGAIAPL
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGLLGTVLGIISSFLAITDGAMQDPTMLAAGVSQALITTAAGMIVAIPALVAYRYFQRRI
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDINAQFETQAGLMVQELYDYQLLENTHIPNTSKQVTHAAVDDSIRDQHSIDRFGLDETA
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TATL
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]