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The map label for this gene is ubiC

Identifier: 92115366

GI number: 92115366

Start: 3625175

End: 3625726

Strand: Direct

Name: ubiC

Synonym: Csal_3251

Alternate gene names: 92115366

Gene position: 3625175-3625726 (Clockwise)

Preceding gene: 92115360

Following gene: 92115367

Centisome position: 98.07

GC content: 69.57

Gene sequence:

>552_bases
ATGTCTCCTGACCGCTTCCCAGGCTGGCCGCACTGGCTGCCCATCGCCGCGCAGCGTCCTCGAATGAGCCCCGACTGGTG
GCCCTGGGTGGCCTCTCGCGATTCACTGACCGCGCGCTTGCGCATCGCCAGCCCCCGTCCATTCTCGGTGCGTCTGCTCA
CCCAGGGCGTGACCAGGCCACGCCTCGACGAAGCCCAGGCACTGGGGCTGCCGCACCGCACGCACGTCTGGCACCGGGAA
GTCCTGTTGCGGCTGGGCAATGCCTCCTGGGTTGCGGCCCGTTCCGTGGCACCGCTGGAGGGACTGTCCGGCGCACGGCT
ATGCACGCTGGGAGAGCGTTCGCTGGGCAGTTGGCTATTTCGGCAACCTAACCTCGAGCGCGGCCCCATCGAAGCGATCC
GTGCGCCGGCCATGACGGGGCTGGACGCCTGGCGAGGCGACGCCGGCCCCTGGGGGCGGCGCTCGCTCCTGCGCGTGGGC
AGAACCAGGATTCTCGTCCAGGAATTCTTTCTCGCCGCGATGGCCGCTGACCTCTCGCTGCCATCGCGCTAA

Upstream 100 bases:

>100_bases
ATATCCACACCCGGCGTGGCGGGCTATCGCTCGAACGCCGAAAAAGCGCGTAAGCTGCGCATGTTACACTAACATCTTTC
TTTTCTAAGCCATCGCTCTC

Downstream 100 bases:

>100_bases
GCTGGCCGCTCACGTTACACAGCCACGTTGCTTTTCACAGCCACGTTGTCATAGGAGAGCCCGATGTCCGCCGACTCATC
CGATGCCGCGCACCCCAGCG

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSPDRFPGWPHWLPIAAQRPRMSPDWWPWVASRDSLTARLRIASPRPFSVRLLTQGVTRPRLDEAQALGLPHRTHVWHRE
VLLRLGNASWVAARSVAPLEGLSGARLCTLGERSLGSWLFRQPNLERGPIEAIRAPAMTGLDAWRGDAGPWGRRSLLRVG
RTRILVQEFFLAAMAADLSLPSR

Sequences:

>Translated_183_residues
MSPDRFPGWPHWLPIAAQRPRMSPDWWPWVASRDSLTARLRIASPRPFSVRLLTQGVTRPRLDEAQALGLPHRTHVWHRE
VLLRLGNASWVAARSVAPLEGLSGARLCTLGERSLGSWLFRQPNLERGPIEAIRAPAMTGLDAWRGDAGPWGRRSLLRVG
RTRILVQEFFLAAMAADLSLPSR
>Mature_182_residues
SPDRFPGWPHWLPIAAQRPRMSPDWWPWVASRDSLTARLRIASPRPFSVRLLTQGVTRPRLDEAQALGLPHRTHVWHREV
LLRLGNASWVAARSVAPLEGLSGARLCTLGERSLGSWLFRQPNLERGPIEAIRAPAMTGLDAWRGDAGPWGRRSLLRVGR
TRILVQEFFLAAMAADLSLPSR

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

Organism=Escherichia coli, GI87082361, Length=160, Percent_Identity=32.5, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_CHRSD (Q1QSG3)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_575294.1
- ProteinModelPortal:   Q1QSG3
- SMR:   Q1QSG3
- STRING:   Q1QSG3
- GeneID:   4029000
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_3251
- NMPDR:   fig|290398.4.peg.2076
- eggNOG:   COG3161
- HOGENOM:   HBG644467
- OMA:   EVCHYPE
- BioCyc:   CSAL290398:CSAL_3251-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 20588; Mature: 20457

Theoretical pI: Translated: 12.30; Mature: 12.30

Prosite motif: NA

Important sites: BINDING 79-79 BINDING 115-115

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDRFPGWPHWLPIAAQRPRMSPDWWPWVASRDSLTARLRIASPRPFSVRLLTQGVTRP
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCC
RLDEAQALGLPHRTHVWHREVLLRLGNASWVAARSVAPLEGLSGARLCTLGERSLGSWLF
CCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEECCCHHHHHHHH
RQPNLERGPIEAIRAPAMTGLDAWRGDAGPWGRRSLLRVGRTRILVQEFFLAAMAADLSL
CCCCCCCCCHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSR
CCC
>Mature Secondary Structure 
SPDRFPGWPHWLPIAAQRPRMSPDWWPWVASRDSLTARLRIASPRPFSVRLLTQGVTRP
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCC
RLDEAQALGLPHRTHVWHREVLLRLGNASWVAARSVAPLEGLSGARLCTLGERSLGSWLF
CCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEECCCHHHHHHHH
RQPNLERGPIEAIRAPAMTGLDAWRGDAGPWGRRSLLRVGRTRILVQEFFLAAMAADLSL
CCCCCCCCCHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA