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The map label for this gene is recG [H]

Identifier: 92115360

GI number: 92115360

Start: 3617974

End: 3620067

Strand: Direct

Name: recG [H]

Synonym: Csal_3245

Alternate gene names: 92115360

Gene position: 3617974-3620067 (Clockwise)

Preceding gene: 92115359

Following gene: 92115366

Centisome position: 97.87

GC content: 68.15

Gene sequence:

>2094_bases
ATGAGCACCGAGACTCAGGCACTGGACGCACCGGTCGGCGAACTCTCCGGGGTGGGCGAGGCATTGACAGCCAAGCTCGC
CCGGCTGGGTATCGTCAGTATCGCCGACATGCTCTTCCATCTGCCGTTGCGGTATCAGGACCGTACGCGCATCACGCCGA
TCGGGACCCTGCGCGCCGGCACCGAGGCCGTGGTCGAGGGCGAAATCGCCGCCGCGGATATCGTCAAGGGACGACGGCGC
AGCCTGCTGGTGCGTCTCAAGGATGGCTCGGGAATTCTCAGCCTGCGGTTCTTTCATTTCTCGCCCGCGCAGCAGCAGCA
GTTCGTGCGCGGCATGCGGGTGCGCGCGTTCGGCGAGGCGCGTGCCGGGGCCACGGGGCTGGAGATCTACCACCCCGAAT
ACCGCCTGCTGCGTCAGGAAGACGCCCCGGTCGAGGAACACCTGACACCGATCTACCCCACCACCGAGGGGCTGGCCCAG
CCCCGCCTGAGGGGCTTGGTCCAGCAGGCGCTCAAGCGCCTCGACGATGATGATGCGGGACTGCCGGACTGGATTCCCGA
TAGCCTGCGCCAGCGCTTTCGCTTGCCGGGCCTGGTCGAGTCGCTGCGTTACCTGCACGAACCTCCGCCCGACGCACCGG
TGGCGCAACTCGCCGAGGGCAAGCATCCGGCGCAACGCCGCCTGGCCCTGGAAGAACTACTCGCGCACCAGCTCAGCCTG
CGCCAGGTACGCCTGCGCATCCAGACGGACAGCGCCCCATCCCTGGGCGGCGGCCGTGGCCTGCAAGCGCGTTTCTTGAC
CCAATTGCCGTTCTCGCTGACCGGTGCGCAGCGGCGAGTGCTCGACGAAATCGGCCACGACCTGGAACGCGCCGTGCCCA
TGCTGCGCCTGGTGCAGGGCGATGTCGGCTCGGGCAAGACCGTGGTCGCCGCAATGGCGGCCCTGGCCGCCATCGCCGGT
GGCTGCCAGGCGGCGATCATGGCGCCCACCGAGATCCTCGCCGAGCAGCACTATCGCAATTTCAGCGACTGGTTCGCGCC
ACTGGGCATCGAGGTCGGCTGGCTGTCCGGCAAGCTCAAGGGCAAGGCGCGCCTGGACACCAAGGCGGCCATCGCCGATG
GTCGTGTGCAGGTCGCCGTGGGCACGCATGCACTGTTCCAGGACGATGTGCGGTTTCACCGCCTGGGCTTGGCGATCATC
GACGAGCAGCACCGTTTCGGCGTCCATCAGCGCCTGGCGTTGCGTCAGAAGGGCGAAGCCGGCGGCCTCACCCCGCATCA
GTTGATCATGACCGCCACCCCGATCCCGCGCACGCTGGCGATGAGCGCCTATGCCGATCTCGACCTGTCGATGATCGACG
AATTGCCGCCCGGTCGAACGCCGGTGCAAACGGTGGCGGTGCCCGACGAACGCCGCCCCGAGGTGGTCGAGCGCATCCAG
CGCGCCTGCGCCGAGGGGCATCAAGCCTATTGGGTATGCACGCTGATCGAGGAGTCCGAGGCACTGACGTGCCAGGCCGC
CGAGGCGACCCATGCCCACCTGGGCGAGGCTCTGCCCGACCTGGCGGTCGGCCTGGTGCACGGGCGCATGAAAGCCGGCG
AGAAAGCCGAGGTCATGGCCGCCTTCACGTCCGGCGAGCTCGATCTGCTGGTCGCCACCACGGTGATCGAGGTCGGGGTG
GACGTGCCCAACGCCAGCCTGATGATCATCGAGAATCCCGAGCGCCTGGGGCTGTCGCAGCTGCATCAGTTGCGTGGCCG
CGTGGGACGCGGCGCGACCGAAAGCTTCTGTGTGCTGCTGTATCATCCGCCGCTGTCGCACCATTCGCGCGAGCGGCTCG
GGGTGATGCGCGACACGACCGACGGCTTCCGCATCGCCGAGAAGGATCTCGAGTTGCGCGGCCCCGGCGAGGTACTCGGC
ACGCGTCAGACGGGCCTGGCGCAGATGAAGATCGCCGACCTGGAGCGCGATCGCGACCTGCTCGACACCATCAGTCCCCT
GGCACGCGCGCTACTCGACGAGGCGCCCGAGGCGGCCACGCCGTTGATTCGTCGCTGGCTGGGCGAAGACGCCGGGCATT
ACGGACAGGTATGA

Upstream 100 bases:

>100_bases
CGGTGGCCATCGCCTGGCGCGCCAGCTTCCCGCGGCCCAAGGCCATCGATGCCCTGACCGCGGCCATCGACGCATGCCAG
CAGCAAAGCATCCAGGCGGC

Downstream 100 bases:

>100_bases
CGTCATGGACGCGGCCATGCGGGAAGGCGCGTCAGGATGAGGGCGGTTCATCGTCGTCGGTCTGGAGGCCCGCCTGCCGC
TCCCACTTGCCGGCCTTGGC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MSTETQALDAPVGELSGVGEALTAKLARLGIVSIADMLFHLPLRYQDRTRITPIGTLRAGTEAVVEGEIAAADIVKGRRR
SLLVRLKDGSGILSLRFFHFSPAQQQQFVRGMRVRAFGEARAGATGLEIYHPEYRLLRQEDAPVEEHLTPIYPTTEGLAQ
PRLRGLVQQALKRLDDDDAGLPDWIPDSLRQRFRLPGLVESLRYLHEPPPDAPVAQLAEGKHPAQRRLALEELLAHQLSL
RQVRLRIQTDSAPSLGGGRGLQARFLTQLPFSLTGAQRRVLDEIGHDLERAVPMLRLVQGDVGSGKTVVAAMAALAAIAG
GCQAAIMAPTEILAEQHYRNFSDWFAPLGIEVGWLSGKLKGKARLDTKAAIADGRVQVAVGTHALFQDDVRFHRLGLAII
DEQHRFGVHQRLALRQKGEAGGLTPHQLIMTATPIPRTLAMSAYADLDLSMIDELPPGRTPVQTVAVPDERRPEVVERIQ
RACAEGHQAYWVCTLIEESEALTCQAAEATHAHLGEALPDLAVGLVHGRMKAGEKAEVMAAFTSGELDLLVATTVIEVGV
DVPNASLMIIENPERLGLSQLHQLRGRVGRGATESFCVLLYHPPLSHHSRERLGVMRDTTDGFRIAEKDLELRGPGEVLG
TRQTGLAQMKIADLERDRDLLDTISPLARALLDEAPEAATPLIRRWLGEDAGHYGQV

Sequences:

>Translated_697_residues
MSTETQALDAPVGELSGVGEALTAKLARLGIVSIADMLFHLPLRYQDRTRITPIGTLRAGTEAVVEGEIAAADIVKGRRR
SLLVRLKDGSGILSLRFFHFSPAQQQQFVRGMRVRAFGEARAGATGLEIYHPEYRLLRQEDAPVEEHLTPIYPTTEGLAQ
PRLRGLVQQALKRLDDDDAGLPDWIPDSLRQRFRLPGLVESLRYLHEPPPDAPVAQLAEGKHPAQRRLALEELLAHQLSL
RQVRLRIQTDSAPSLGGGRGLQARFLTQLPFSLTGAQRRVLDEIGHDLERAVPMLRLVQGDVGSGKTVVAAMAALAAIAG
GCQAAIMAPTEILAEQHYRNFSDWFAPLGIEVGWLSGKLKGKARLDTKAAIADGRVQVAVGTHALFQDDVRFHRLGLAII
DEQHRFGVHQRLALRQKGEAGGLTPHQLIMTATPIPRTLAMSAYADLDLSMIDELPPGRTPVQTVAVPDERRPEVVERIQ
RACAEGHQAYWVCTLIEESEALTCQAAEATHAHLGEALPDLAVGLVHGRMKAGEKAEVMAAFTSGELDLLVATTVIEVGV
DVPNASLMIIENPERLGLSQLHQLRGRVGRGATESFCVLLYHPPLSHHSRERLGVMRDTTDGFRIAEKDLELRGPGEVLG
TRQTGLAQMKIADLERDRDLLDTISPLARALLDEAPEAATPLIRRWLGEDAGHYGQV
>Mature_696_residues
STETQALDAPVGELSGVGEALTAKLARLGIVSIADMLFHLPLRYQDRTRITPIGTLRAGTEAVVEGEIAAADIVKGRRRS
LLVRLKDGSGILSLRFFHFSPAQQQQFVRGMRVRAFGEARAGATGLEIYHPEYRLLRQEDAPVEEHLTPIYPTTEGLAQP
RLRGLVQQALKRLDDDDAGLPDWIPDSLRQRFRLPGLVESLRYLHEPPPDAPVAQLAEGKHPAQRRLALEELLAHQLSLR
QVRLRIQTDSAPSLGGGRGLQARFLTQLPFSLTGAQRRVLDEIGHDLERAVPMLRLVQGDVGSGKTVVAAMAALAAIAGG
CQAAIMAPTEILAEQHYRNFSDWFAPLGIEVGWLSGKLKGKARLDTKAAIADGRVQVAVGTHALFQDDVRFHRLGLAIID
EQHRFGVHQRLALRQKGEAGGLTPHQLIMTATPIPRTLAMSAYADLDLSMIDELPPGRTPVQTVAVPDERRPEVVERIQR
ACAEGHQAYWVCTLIEESEALTCQAAEATHAHLGEALPDLAVGLVHGRMKAGEKAEVMAAFTSGELDLLVATTVIEVGVD
VPNASLMIIENPERLGLSQLHQLRGRVGRGATESFCVLLYHPPLSHHSRERLGVMRDTTDGFRIAEKDLELRGPGEVLGT
RQTGLAQMKIADLERDRDLLDTISPLARALLDEAPEAATPLIRRWLGEDAGHYGQV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=686, Percent_Identity=60.3498542274053, Blast_Score=771, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=386, Percent_Identity=38.60103626943, Blast_Score=242, Evalue=6e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76188; Mature: 76056

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTETQALDAPVGELSGVGEALTAKLARLGIVSIADMLFHLPLRYQDRTRITPIGTLRAG
CCCCCCHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
TEAVVEGEIAAADIVKGRRRSLLVRLKDGSGILSLRFFHFSPAQQQQFVRGMRVRAFGEA
CHHHHCCCHHHHHHHCCCCEEEEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCC
RAGATGLEIYHPEYRLLRQEDAPVEEHLTPIYPTTEGLAQPRLRGLVQQALKRLDDDDAG
CCCCCCEEEECCHHHHHHCCCCCHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCC
LPDWIPDSLRQRFRLPGLVESLRYLHEPPPDAPVAQLAEGKHPAQRRLALEELLAHQLSL
CCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RQVRLRIQTDSAPSLGGGRGLQARFLTQLPFSLTGAQRRVLDEIGHDLERAVPMLRLVQG
HHHEEEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DVGSGKTVVAAMAALAAIAGGCQAAIMAPTEILAEQHYRNFSDWFAPLGIEVGWLSGKLK
CCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCHHHHHHHCCCEEEEECCCCC
GKARLDTKAAIADGRVQVAVGTHALFQDDVRFHRLGLAIIDEQHRFGVHQRLALRQKGEA
CCCCCCCHHHCCCCEEEEEECCHHHHHHCHHHHHHHHHEECCHHHHCHHHHHHHHHCCCC
GGLTPHQLIMTATPIPRTLAMSAYADLDLSMIDELPPGRTPVQTVAVPDERRPEVVERIQ
CCCCHHHEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHH
RACAEGHQAYWVCTLIEESEALTCQAAEATHAHLGEALPDLAVGLVHGRMKAGEKAEVMA
HHHHCCCCEEEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AFTSGELDLLVATTVIEVGVDVPNASLMIIENPERLGLSQLHQLRGRVGRGATESFCVLL
EECCCCEEEHHHHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHHHCCCCCCCCEEEEE
YHPPLSHHSRERLGVMRDTTDGFRIAEKDLELRGPGEVLGTRQTGLAQMKIADLERDRDL
ECCCCCCCCHHHHCCCCCCCCCCEEECCCCCCCCCCHHCCCCCCCHHHHHHHHHHCCHHH
LDTISPLARALLDEAPEAATPLIRRWLGEDAGHYGQV
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
STETQALDAPVGELSGVGEALTAKLARLGIVSIADMLFHLPLRYQDRTRITPIGTLRAG
CCCCCHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
TEAVVEGEIAAADIVKGRRRSLLVRLKDGSGILSLRFFHFSPAQQQQFVRGMRVRAFGEA
CHHHHCCCHHHHHHHCCCCEEEEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCC
RAGATGLEIYHPEYRLLRQEDAPVEEHLTPIYPTTEGLAQPRLRGLVQQALKRLDDDDAG
CCCCCCEEEECCHHHHHHCCCCCHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCC
LPDWIPDSLRQRFRLPGLVESLRYLHEPPPDAPVAQLAEGKHPAQRRLALEELLAHQLSL
CCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RQVRLRIQTDSAPSLGGGRGLQARFLTQLPFSLTGAQRRVLDEIGHDLERAVPMLRLVQG
HHHEEEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DVGSGKTVVAAMAALAAIAGGCQAAIMAPTEILAEQHYRNFSDWFAPLGIEVGWLSGKLK
CCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCHHHHHHHCCCEEEEECCCCC
GKARLDTKAAIADGRVQVAVGTHALFQDDVRFHRLGLAIIDEQHRFGVHQRLALRQKGEA
CCCCCCCHHHCCCCEEEEEECCHHHHHHCHHHHHHHHHEECCHHHHCHHHHHHHHHCCCC
GGLTPHQLIMTATPIPRTLAMSAYADLDLSMIDELPPGRTPVQTVAVPDERRPEVVERIQ
CCCCHHHEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHH
RACAEGHQAYWVCTLIEESEALTCQAAEATHAHLGEALPDLAVGLVHGRMKAGEKAEVMA
HHHHCCCCEEEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AFTSGELDLLVATTVIEVGVDVPNASLMIIENPERLGLSQLHQLRGRVGRGATESFCVLL
EECCCCEEEHHHHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHHHCCCCCCCCEEEEE
YHPPLSHHSRERLGVMRDTTDGFRIAEKDLELRGPGEVLGTRQTGLAQMKIADLERDRDL
ECCCCCCCCHHHHCCCCCCCCCCEEECCCCCCCCCCHHCCCCCCCHHHHHHHHHHCCHHH
LDTISPLARALLDEAPEAATPLIRRWLGEDAGHYGQV
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]