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The map label for this gene is ubiA

Identifier: 92115367

GI number: 92115367

Start: 3625790

End: 3626686

Strand: Direct

Name: ubiA

Synonym: Csal_3252

Alternate gene names: 92115367

Gene position: 3625790-3626686 (Clockwise)

Preceding gene: 92115366

Following gene: 92115368

Centisome position: 98.08

GC content: 65.11

Gene sequence:

>897_bases
ATGTCCGCCGACTCATCCGATGCCGCGCACCCCAGCGGCCTGGCCCGCGTGCCGGACTTTCTGCGCTTGACACGACTCGA
CCGCCCCATCGGCACCTGGCTGCTGATGTGGCCGACGTTGTGGGCGCTGTGGCTGGCGGCCGAGGGTATCCCCGAACGCG
GTACGCTGCTGATCTTCGTCATCGGCGTGTACGTGATGCGCGCCGCCGGTTGCGTGGTCAACGACTACGCCGATCGCCAT
TTCGATGGGCACGTCAAGCGTACCCGCGACCGGCCACTGGCTACCGGACGCATCACCGAGAAAGAAGCCAAGGTGCTCTT
CGCGGGCCTGGTGATCATTGCCTTCGGCCTGGTCTGCCTGACCAATCTGCCAACCGTGCTGCTGTCCTTCGCGGCACTGG
CCCTGGCGGCCACCTACCCGTTCATGAAACGCTATACGCACTTCCCCCAGGTAGTGCTGGGGGCTGCCTTCTCGTGGGGG
ATCCCCATGGCGTTCATGGCCATTCAACGCCAGGTACCGCTGGAAGCCTGGCTACTGCTCGCCGCCAACGTGGCCTGGAC
GGTGGCCTACGATACCGAATATGCCATGGTCGACCGCGATGACGACCTGAAGGTCGGCATCAAGTCCACGGCGGTGCTGT
TCGGGCGCGCCGACCGCCTGATGATCGGACTGCTGCAGGCGCTGACCCTGCTGCTGCTGGCCTGGGTCGGCCTGCGCCTG
GCGCTGGGAGGCTTCTTCTGGCTGGGGCTGGCTGCGATGGGGGCGATCTTCGTCTTCCAGCACCGCCTGATCCGCCATCG
CGAACGCGACCATTGCTTCCGGGCCTTTCTCAACAATCATTGGGCCGGTCTGGTGGTCTTCGCGGGCATCGCCTTGTCGC
TATGGCCTATGCTATAG

Upstream 100 bases:

>100_bases
CGCGATGGCCGCTGACCTCTCGCTGCCATCGCGCTAAGCTGGCCGCTCACGTTACACAGCCACGTTGCTTTTCACAGCCA
CGTTGTCATAGGAGAGCCCG

Downstream 100 bases:

>100_bases
ATCGCGTGTCACGAAGTTGTCACATTAGCGCGTTGTAATCGTCATGCTGATGTCATTCATGAGTGATTCGCGCCATCGCG
ATCCGCAAGAGGCCTACGCC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSADSSDAAHPSGLARVPDFLRLTRLDRPIGTWLLMWPTLWALWLAAEGIPERGTLLIFVIGVYVMRAAGCVVNDYADRH
FDGHVKRTRDRPLATGRITEKEAKVLFAGLVIIAFGLVCLTNLPTVLLSFAALALAATYPFMKRYTHFPQVVLGAAFSWG
IPMAFMAIQRQVPLEAWLLLAANVAWTVAYDTEYAMVDRDDDLKVGIKSTAVLFGRADRLMIGLLQALTLLLLAWVGLRL
ALGGFFWLGLAAMGAIFVFQHRLIRHRERDHCFRAFLNNHWAGLVVFAGIALSLWPML

Sequences:

>Translated_298_residues
MSADSSDAAHPSGLARVPDFLRLTRLDRPIGTWLLMWPTLWALWLAAEGIPERGTLLIFVIGVYVMRAAGCVVNDYADRH
FDGHVKRTRDRPLATGRITEKEAKVLFAGLVIIAFGLVCLTNLPTVLLSFAALALAATYPFMKRYTHFPQVVLGAAFSWG
IPMAFMAIQRQVPLEAWLLLAANVAWTVAYDTEYAMVDRDDDLKVGIKSTAVLFGRADRLMIGLLQALTLLLLAWVGLRL
ALGGFFWLGLAAMGAIFVFQHRLIRHRERDHCFRAFLNNHWAGLVVFAGIALSLWPML
>Mature_297_residues
SADSSDAAHPSGLARVPDFLRLTRLDRPIGTWLLMWPTLWALWLAAEGIPERGTLLIFVIGVYVMRAAGCVVNDYADRHF
DGHVKRTRDRPLATGRITEKEAKVLFAGLVIIAFGLVCLTNLPTVLLSFAALALAATYPFMKRYTHFPQVVLGAAFSWGI
PMAFMAIQRQVPLEAWLLLAANVAWTVAYDTEYAMVDRDDDLKVGIKSTAVLFGRADRLMIGLLQALTLLLLAWVGLRLA
LGGFFWLGLAAMGAIFVFQHRLIRHRERDHCFRAFLNNHWAGLVVFAGIALSLWPML

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=281, Percent_Identity=38.4341637010676, Blast_Score=179, Evalue=2e-45,
Organism=Escherichia coli, GI1790473, Length=277, Percent_Identity=62.4548736462094, Blast_Score=334, Evalue=5e-93,
Organism=Caenorhabditis elegans, GI17553718, Length=295, Percent_Identity=35.9322033898305, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI32565247, Length=295, Percent_Identity=35.2542372881356, Blast_Score=164, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17553720, Length=352, Percent_Identity=30.3977272727273, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI32565245, Length=155, Percent_Identity=42.5806451612903, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI32565243, Length=154, Percent_Identity=42.2077922077922, Blast_Score=111, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324370, Length=286, Percent_Identity=34.2657342657343, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21355567, Length=276, Percent_Identity=38.0434782608696, Blast_Score=187, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_CHRSD (Q1QSG2)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_575295.1
- STRING:   Q1QSG2
- GeneID:   4029001
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_3252
- NMPDR:   fig|290398.4.peg.2077
- eggNOG:   COG0382
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- BioCyc:   CSAL290398:CSAL_3252-MONOMER
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 33191; Mature: 33060

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b74ed84)-; HASH(0x147f89dc)-; HASH(0x1b922b60)-; HASH(0x14c2dd6c)-; HASH(0x1b4a94d8)-; HASH(0x14be8058)-; HASH(0x14291a60)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADSSDAAHPSGLARVPDFLRLTRLDRPIGTWLLMWPTLWALWLAAEGIPERGTLLIFV
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
IGVYVMRAAGCVVNDYADRHFDGHVKRTRDRPLATGRITEKEAKVLFAGLVIIAFGLVCL
HHHHHHHHCCHHHHHHHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TNLPTVLLSFAALALAATYPFMKRYTHFPQVVLGAAFSWGIPMAFMAIQRQVPLEAWLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
AANVAWTVAYDTEYAMVDRDDDLKVGIKSTAVLFGRADRLMIGLLQALTLLLLAWVGLRL
HHHHEEEEEECCEEEEECCCCCCEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ALGGFFWLGLAAMGAIFVFQHRLIRHRERDHCFRAFLNNHWAGLVVFAGIALSLWPML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SADSSDAAHPSGLARVPDFLRLTRLDRPIGTWLLMWPTLWALWLAAEGIPERGTLLIFV
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
IGVYVMRAAGCVVNDYADRHFDGHVKRTRDRPLATGRITEKEAKVLFAGLVIIAFGLVCL
HHHHHHHHCCHHHHHHHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TNLPTVLLSFAALALAATYPFMKRYTHFPQVVLGAAFSWGIPMAFMAIQRQVPLEAWLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
AANVAWTVAYDTEYAMVDRDDDLKVGIKSTAVLFGRADRLMIGLLQALTLLLLAWVGLRL
HHHHEEEEEECCEEEEECCCCCCEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ALGGFFWLGLAAMGAIFVFQHRLIRHRERDHCFRAFLNNHWAGLVVFAGIALSLWPML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA