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The map label for this gene is pdxA [H]

Identifier: 92115309

GI number: 92115309

Start: 3561101

End: 3562135

Strand: Direct

Name: pdxA [H]

Synonym: Csal_3194

Alternate gene names: 92115309

Gene position: 3561101-3562135 (Clockwise)

Preceding gene: 92115304

Following gene: 92115310

Centisome position: 96.33

GC content: 57.58

Gene sequence:

>1035_bases
ATGACACCGCATAACGACAACCAAGATACTCGTGTCCGCCCCCTCATCGGCATCGTCCTGGGCGACCCAGCTGGCATTGG
ACCGGAGTTGATCGCCAAGCTTCTGGCGGACCCTGCCTCTCAGGAAAGCGGCCATGCGGTGCTGGTTGCCGACACTTGGC
TCTGGGAAGAAGGCCAGCGCATCGCCGGCACTCGGCTCGATTTACCTGTGATCGAACGCTTCGCCGAGGCACGCGAATAC
ACGACCCCCGTACTGATGCCCATCGATAGTATTTCTCGCGACGAGACTCGCTACGGCGAAGCGAACGCGGCGGGCGGACG
TTCTGCGCGCCATGCCCTGACGCAATGTCTAGATGCCGCCGTACGGGGTGATATCGACGGGATTTGCTTCGGCCCGCTGA
ACAAGTATGCCATGAAGCTCGGAGGCATGAACTTCGAGGACGAACTGGGATTCTTCGCCGATTATTTGGGTGTCAATGAT
TACACCTGCGAGTTCAATACATTCGGAAGTATCTGGACCTCGCGTATCTCATCACATATTCCATTGAAGGATGCGCCTTC
CTACGTCACGCGTGAACGTATCCTGAAAGCGGCACGCCTCACCGATAAGTCACTACGTTTGGCCGGATTTGCTGAACCAC
GCATCGCCGTCGCGGCATTCAATCCACATGGTGGCGAGAGTGGAACCTGCGGTCGCGAGGAAGTTGACACTATTGCCCCG
GCAGTGGAAGAAGCGCAAGACGAGGGGCTCACAGTGTCCGGCCCTCACCCTGCTGACACATTATTTCTCAAAGTGCGCGA
CGGGGAATATGACGCCGTGGTCACCATGTTTCACGACCAAGGGCAGATCGCCATAAAGCTTCTCGGTTTTCATGAAGGGG
TCACGGTTCATGGCGGCCTGCCGGTGCCCATTACCACACCAGCACACGGTACGGCCTATGACATCGCCAGCTCTGGGAAA
GCCAACCTGCGCCCCACTCACAATGCTTTCAAATTGGCTTGCCAAATGGCGGCCAGCAACCGGCTTTCCAGCTAA

Upstream 100 bases:

>100_bases
CTAGGCTTGACGTTAACTGGACTGGTAATACAACCAGAAGACCAGATAACGGCAAAAGCATCACCAATTGCACGATGCAG
CATTAAAGGACCCAGCCCCC

Downstream 100 bases:

>100_bases
CTCCTCATCACGACGCTAGACGGACAAGATTATGAAAATCACGCGCGTAAGAGCCCGCGTCTTCGAATGGAAAGGCGACA
CAGTGCCACCGCAGCCGCAT

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase 2 [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTPHNDNQDTRVRPLIGIVLGDPAGIGPELIAKLLADPASQESGHAVLVADTWLWEEGQRIAGTRLDLPVIERFAEAREY
TTPVLMPIDSISRDETRYGEANAAGGRSARHALTQCLDAAVRGDIDGICFGPLNKYAMKLGGMNFEDELGFFADYLGVND
YTCEFNTFGSIWTSRISSHIPLKDAPSYVTRERILKAARLTDKSLRLAGFAEPRIAVAAFNPHGGESGTCGREEVDTIAP
AVEEAQDEGLTVSGPHPADTLFLKVRDGEYDAVVTMFHDQGQIAIKLLGFHEGVTVHGGLPVPITTPAHGTAYDIASSGK
ANLRPTHNAFKLACQMAASNRLSS

Sequences:

>Translated_344_residues
MTPHNDNQDTRVRPLIGIVLGDPAGIGPELIAKLLADPASQESGHAVLVADTWLWEEGQRIAGTRLDLPVIERFAEAREY
TTPVLMPIDSISRDETRYGEANAAGGRSARHALTQCLDAAVRGDIDGICFGPLNKYAMKLGGMNFEDELGFFADYLGVND
YTCEFNTFGSIWTSRISSHIPLKDAPSYVTRERILKAARLTDKSLRLAGFAEPRIAVAAFNPHGGESGTCGREEVDTIAP
AVEEAQDEGLTVSGPHPADTLFLKVRDGEYDAVVTMFHDQGQIAIKLLGFHEGVTVHGGLPVPITTPAHGTAYDIASSGK
ANLRPTHNAFKLACQMAASNRLSS
>Mature_343_residues
TPHNDNQDTRVRPLIGIVLGDPAGIGPELIAKLLADPASQESGHAVLVADTWLWEEGQRIAGTRLDLPVIERFAEAREYT
TPVLMPIDSISRDETRYGEANAAGGRSARHALTQCLDAAVRGDIDGICFGPLNKYAMKLGGMNFEDELGFFADYLGVNDY
TCEFNTFGSIWTSRISSHIPLKDAPSYVTRERILKAARLTDKSLRLAGFAEPRIAVAAFNPHGGESGTCGREEVDTIAPA
VEEAQDEGLTVSGPHPADTLFLKVRDGEYDAVVTMFHDQGQIAIKLLGFHEGVTVHGGLPVPITTPAHGTAYDIASSGKA
NLRPTHNAFKLACQMAASNRLSS

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=31.2883435582822, Blast_Score=147, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 37039; Mature: 36908

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHNDNQDTRVRPLIGIVLGDPAGIGPELIAKLLADPASQESGHAVLVADTWLWEEGQR
CCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECEECCCCCE
IAGTRLDLPVIERFAEAREYTTPVLMPIDSISRDETRYGEANAAGGRSARHALTQCLDAA
ECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHH
VRGDIDGICFGPLNKYAMKLGGMNFEDELGFFADYLGVNDYTCEFNTFGSIWTSRISSHI
HHCCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCC
PLKDAPSYVTRERILKAARLTDKSLRLAGFAEPRIAVAAFNPHGGESGTCGREEVDTIAP
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
AVEEAQDEGLTVSGPHPADTLFLKVRDGEYDAVVTMFHDQGQIAIKLLGFHEGVTVHGGL
HHHHHHHCCEEECCCCCCCEEEEEEECCCCEEEEEEEECCCEEEEEEEEECCCEEEECCC
PVPITTPAHGTAYDIASSGKANLRPTHNAFKLACQMAASNRLSS
CCEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TPHNDNQDTRVRPLIGIVLGDPAGIGPELIAKLLADPASQESGHAVLVADTWLWEEGQR
CCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECEECCCCCE
IAGTRLDLPVIERFAEAREYTTPVLMPIDSISRDETRYGEANAAGGRSARHALTQCLDAA
ECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHH
VRGDIDGICFGPLNKYAMKLGGMNFEDELGFFADYLGVNDYTCEFNTFGSIWTSRISSHI
HHCCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCC
PLKDAPSYVTRERILKAARLTDKSLRLAGFAEPRIAVAAFNPHGGESGTCGREEVDTIAP
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
AVEEAQDEGLTVSGPHPADTLFLKVRDGEYDAVVTMFHDQGQIAIKLLGFHEGVTVHGGL
HHHHHHHCCEEECCCCCCCEEEEEEECCCCEEEEEEEECCCEEEEEEEEECCCEEEECCC
PVPITTPAHGTAYDIASSGKANLRPTHNAFKLACQMAASNRLSS
CCEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]