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The map label for this gene is fmt

Identifier: 92114985

GI number: 92114985

Start: 3199297

End: 3200274

Strand: Direct

Name: fmt

Synonym: Csal_2868

Alternate gene names: 92114985

Gene position: 3199297-3200274 (Clockwise)

Preceding gene: 92114984

Following gene: 92114986

Centisome position: 86.55

GC content: 72.39

Gene sequence:

>978_bases
ATGTCCCACTCCCTGCGCGTCGTCTTCGCCGGCACGCCCGATTTCGCCGCCGCGAGTCTCTTGGCGCTGCTCGACAGCCG
TCACCAGGTGGTCGCCGCGTACACCCAGCCGGACCGACCGGCCGGTCGCGGGCGCAAACTCACGCCCAGCCCGGTCAAGG
CGCTGGCGCAGGAGCACGGCCTGCCCGTCCATCAGCCCACCAGCCTCAAGGATACCGACGCCCAGCAGACGCTCGCCGCG
CTCGAGGCCGATGTCCTGGTGGTCGTCGCCTATGGCTTGATACTGCCGCAGGCCGTTCTCGATATCCCGCGCCTGGGATG
CCTCAACGTCCATGCGTCACTGCTGCCACGCTGGCGCGGTGCGGCGCCGATCCAGCGTGCCATCGAGGCCGGGGACACAC
GCAGCGGCGTGACCATCATGCAGATGGACGCCGGGCTCGACACCGGCGCCATGCTGCTGGTGCGCGAGACGCCGATCACG
GCGACCACCACTGGTGGCGAGCTGCACGACCGCCTCGCCCCGCTCGGTGGCGAGGCCATCGTCGAGGCGCTCGACGCCCT
GGCGACGGACGGCCTGACGGCGACGCCCCAGCCGAGCGAAGGCGTCACCTATGCCGCCAAGCTCAGCAAGGCCGAGGCCG
AGCTCGACTTCACGCGGCCGGCCCACGAGCTGGCCGCCCGCGTGCGTGCCTTCAACCCCTGGCCGGTGGCCTGGACGCGC
CTGGCTGGCGAGCCGCTGCGGCTATGGCTGGCGGAGGCCGAAGCAGAGGCCGAGCGCCCCGGCGTCGCGCCCGGCACCCT
GCTGCAGAGCGCCCCGGATGCCCTGCGCATCGCCTGCGGTCACGACGGCACCCAGGTGGTGCGCATTACCCGTGCCCAGC
TGCCCGGCGGCAAGCCGCTGGCCGTGCGCGACCTGCTCAACGCACGTGGCGAGCGCTTTCCCGAGGGGCTTCGTCTGGGA
CAGGAGGATCGCGCGTGA

Upstream 100 bases:

>100_bases
TGCCATGCGGGCCGGCAATCGCCGGCCCGTCGCGTTTGCCGCCCCGGCGCCGCACCCGCCTTCGCCACGCACCATTACCG
CCGTCACGGAAGCCTTCTCG

Downstream 100 bases:

>100_bases
GCACTCCGGACATGCGTGCCGTATGCGCCAGCGCACTGGCGCCACTTCTCGACGGCAAGGGCTCGCTGAGCGCCCTGGAT
GCACATCTCGACACCGCCAG

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSHSLRVVFAGTPDFAAASLLALLDSRHQVVAAYTQPDRPAGRGRKLTPSPVKALAQEHGLPVHQPTSLKDTDAQQTLAA
LEADVLVVVAYGLILPQAVLDIPRLGCLNVHASLLPRWRGAAPIQRAIEAGDTRSGVTIMQMDAGLDTGAMLLVRETPIT
ATTTGGELHDRLAPLGGEAIVEALDALATDGLTATPQPSEGVTYAAKLSKAEAELDFTRPAHELAARVRAFNPWPVAWTR
LAGEPLRLWLAEAEAEAERPGVAPGTLLQSAPDALRIACGHDGTQVVRITRAQLPGGKPLAVRDLLNARGERFPEGLRLG
QEDRA

Sequences:

>Translated_325_residues
MSHSLRVVFAGTPDFAAASLLALLDSRHQVVAAYTQPDRPAGRGRKLTPSPVKALAQEHGLPVHQPTSLKDTDAQQTLAA
LEADVLVVVAYGLILPQAVLDIPRLGCLNVHASLLPRWRGAAPIQRAIEAGDTRSGVTIMQMDAGLDTGAMLLVRETPIT
ATTTGGELHDRLAPLGGEAIVEALDALATDGLTATPQPSEGVTYAAKLSKAEAELDFTRPAHELAARVRAFNPWPVAWTR
LAGEPLRLWLAEAEAEAERPGVAPGTLLQSAPDALRIACGHDGTQVVRITRAQLPGGKPLAVRDLLNARGERFPEGLRLG
QEDRA
>Mature_324_residues
SHSLRVVFAGTPDFAAASLLALLDSRHQVVAAYTQPDRPAGRGRKLTPSPVKALAQEHGLPVHQPTSLKDTDAQQTLAAL
EADVLVVVAYGLILPQAVLDIPRLGCLNVHASLLPRWRGAAPIQRAIEAGDTRSGVTIMQMDAGLDTGAMLLVRETPITA
TTTGGELHDRLAPLGGEAIVEALDALATDGLTATPQPSEGVTYAAKLSKAEAELDFTRPAHELAARVRAFNPWPVAWTRL
AGEPLRLWLAEAEAEAERPGVAPGTLLQSAPDALRIACGHDGTQVVRITRAQLPGGKPLAVRDLLNARGERFPEGLRLGQ
EDRA

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family

Homologues:

Organism=Homo sapiens, GI238814322, Length=257, Percent_Identity=28.4046692607004, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI21614513, Length=251, Percent_Identity=28.6852589641434, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI164663775, Length=232, Percent_Identity=33.6206896551724, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1789683, Length=321, Percent_Identity=55.7632398753894, Blast_Score=335, Evalue=2e-93,
Organism=Escherichia coli, GI1788589, Length=282, Percent_Identity=28.0141843971631, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI133930964, Length=259, Percent_Identity=26.6409266409266, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6319458, Length=205, Percent_Identity=29.2682926829268, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550868, Length=324, Percent_Identity=30.8641975308642, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI28571984, Length=245, Percent_Identity=33.469387755102, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24585660, Length=243, Percent_Identity=28.8065843621399, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): FMT_CHRSD (Q1QTJ4)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_574913.1
- ProteinModelPortal:   Q1QTJ4
- SMR:   Q1QTJ4
- STRING:   Q1QTJ4
- GeneID:   4028670
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2868
- NMPDR:   fig|290398.4.peg.2562
- eggNOG:   COG0223
- HOGENOM:   HBG571560
- OMA:   IMQMDEG
- BioCyc:   CSAL290398:CSAL_2868-MONOMER
- HAMAP:   MF_00182
- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518
- Gene3D:   G3DSA:3.10.25.10
- Gene3D:   G3DSA:3.40.50.170
- PANTHER:   PTHR11138
- TIGRFAMs:   TIGR00460

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N; SSF50486 FMT_C_like; SSF53328 formyl_transf

EC number: =2.1.2.9

Molecular weight: Translated: 34434; Mature: 34303

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSLRVVFAGTPDFAAASLLALLDSRHQVVAAYTQPDRPAGRGRKLTPSPVKALAQEHG
CCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCC
LPVHQPTSLKDTDAQQTLAALEADVLVVVAYGLILPQAVLDIPRLGCLNVHASLLPRWRG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
AAPIQRAIEAGDTRSGVTIMQMDAGLDTGAMLLVRETPITATTTGGELHDRLAPLGGEAI
CHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCCEEECCCCHHHHHHCCCCHHHH
VEALDALATDGLTATPQPSEGVTYAAKLSKAEAELDFTRPAHELAARVRAFNPWPVAWTR
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHH
LAGEPLRLWLAEAEAEAERPGVAPGTLLQSAPDALRIACGHDGTQVVRITRAQLPGGKPL
HCCCCCEEEEHHHHHHHCCCCCCCHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCH
AVRDLLNARGERFPEGLRLGQEDRA
HHHHHHHHHHHCCCHHHCCCCCCCC
>Mature Secondary Structure 
SHSLRVVFAGTPDFAAASLLALLDSRHQVVAAYTQPDRPAGRGRKLTPSPVKALAQEHG
CCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCC
LPVHQPTSLKDTDAQQTLAALEADVLVVVAYGLILPQAVLDIPRLGCLNVHASLLPRWRG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
AAPIQRAIEAGDTRSGVTIMQMDAGLDTGAMLLVRETPITATTTGGELHDRLAPLGGEAI
CHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCCEEECCCCHHHHHHCCCCHHHH
VEALDALATDGLTATPQPSEGVTYAAKLSKAEAELDFTRPAHELAARVRAFNPWPVAWTR
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHH
LAGEPLRLWLAEAEAEAERPGVAPGTLLQSAPDALRIACGHDGTQVVRITRAQLPGGKPL
HCCCCCEEEEHHHHHHHCCCCCCCHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCH
AVRDLLNARGERFPEGLRLGQEDRA
HHHHHHHHHHHCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA