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The map label for this gene is yafV [C]

Identifier: 92114959

GI number: 92114959

Start: 3173836

End: 3174618

Strand: Direct

Name: yafV [C]

Synonym: Csal_2842

Alternate gene names: 92114959

Gene position: 3173836-3174618 (Clockwise)

Preceding gene: 92114958

Following gene: 92114960

Centisome position: 85.86

GC content: 68.58

Gene sequence:

>783_bases
ATGAAACTGATGCTGGCGCAGACCGACCCCGTGTGCGGCGACGTGGCCGCCAACCTGGCGTCTCTTGCGCGCCAGTGCCA
GCAGGCGGTGGCGGCCGGTGCGGACCTGCTGGTCCTCCCCGAGCTCGCCCTGAGCGGCTACAACATCTTCGAGCGACTGG
AGGAACTCGCCGAGCCGGTGGGCGGCCCGATCGCCCAGCGGGCCGCCGAGCTCGCCGCCGAGCACGAACTGTTCCTGCTC
TTCGGCCTGGCCGAGCGGCAAGCCGACGGGCGCCTGACCAATTCCGCCGTGCTGATCGACGACCGGGGCGAGCGTATCGC
CACCTACCACAAGCGCCAGCTGTGGGATCGCGAACATGCCTTCTTCGCCGCCGGCGAGGACTGCTGCGTGGTGGAGACGC
GCCTCGGCCGCCTCGGCCTGATGATCTGCTATGACAACGAGTTTCCCGAGGTGGCCAGGGCGCTCGCCACTCAAGGGGCT
CAGGTCATCCTCTCGCCCACCGCCAACATGGTGCCCAATGCCGAGCGCCAGGCGCTGCAGATCCGGGCCCGGGCCCTCGA
CAACCAGTGCTTCGTCGCCTGCATCAACCGGGCCGGCGAGGAAGCCGAACTGCATTATTGCGGCAACAGCCTGATAGCGG
GACCGGATGGCGAGGTTCTGGGGCGCCTCGGTGACGCGGCGGGCAGCCTGGTGGTCGACATCGACCTGAGCCGCATCGAC
GCAAGCCGCGCCCATCAGGACTACCTCCAGGACCTCAGGCCGATGCCGGAGACAATCGCATGA

Upstream 100 bases:

>100_bases
TGCCGGTCTTCATCATCACCGGCGGCCTCTACTGGCTCGGCGCCATGCTGTTGACAAAGTCCCGCGCCAACGCTTCACAG
ACCGCAGGAGAGTGACACCG

Downstream 100 bases:

>100_bases
GCCGTTTCTCGCTTCCTCGGGGCGATGCCGCGAGCTGGTATCGCACCACCTCGCTCGATGACGGGATCACGCGGATCGAC
GAGCCCGCCATCAAGCCGTT

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKLMLAQTDPVCGDVAANLASLARQCQQAVAAGADLLVLPELALSGYNIFERLEELAEPVGGPIAQRAAELAAEHELFLL
FGLAERQADGRLTNSAVLIDDRGERIATYHKRQLWDREHAFFAAGEDCCVVETRLGRLGLMICYDNEFPEVARALATQGA
QVILSPTANMVPNAERQALQIRARALDNQCFVACINRAGEEAELHYCGNSLIAGPDGEVLGRLGDAAGSLVVDIDLSRID
ASRAHQDYLQDLRPMPETIA

Sequences:

>Translated_260_residues
MKLMLAQTDPVCGDVAANLASLARQCQQAVAAGADLLVLPELALSGYNIFERLEELAEPVGGPIAQRAAELAAEHELFLL
FGLAERQADGRLTNSAVLIDDRGERIATYHKRQLWDREHAFFAAGEDCCVVETRLGRLGLMICYDNEFPEVARALATQGA
QVILSPTANMVPNAERQALQIRARALDNQCFVACINRAGEEAELHYCGNSLIAGPDGEVLGRLGDAAGSLVVDIDLSRID
ASRAHQDYLQDLRPMPETIA
>Mature_260_residues
MKLMLAQTDPVCGDVAANLASLARQCQQAVAAGADLLVLPELALSGYNIFERLEELAEPVGGPIAQRAAELAAEHELFLL
FGLAERQADGRLTNSAVLIDDRGERIATYHKRQLWDREHAFFAAGEDCCVVETRLGRLGLMICYDNEFPEVARALATQGA
QVILSPTANMVPNAERQALQIRARALDNQCFVACINRAGEEAELHYCGNSLIAGPDGEVLGRLGDAAGSLVVDIDLSRID
ASRAHQDYLQDLRPMPETIA

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=264, Percent_Identity=30.6818181818182, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI297632348, Length=264, Percent_Identity=30.6818181818182, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI297632350, Length=264, Percent_Identity=30.6818181818182, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI9910460, Length=233, Percent_Identity=30.4721030042918, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1786412, Length=241, Percent_Identity=29.4605809128631, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17556280, Length=258, Percent_Identity=29.0697674418605, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17533173, Length=268, Percent_Identity=27.2388059701493, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323383, Length=261, Percent_Identity=26.8199233716475, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17933642, Length=244, Percent_Identity=29.0983606557377, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21355835, Length=257, Percent_Identity=27.2373540856031, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21358471, Length=265, Percent_Identity=23.7735849056604, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28152; Mature: 28152

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMLAQTDPVCGDVAANLASLARQCQQAVAAGADLLVLPELALSGYNIFERLEELAEPV
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCHHHHHHHHHHHHHC
GGPIAQRAAELAAEHELFLLFGLAERQADGRLTNSAVLIDDRGERIATYHKRQLWDREHA
CCHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
FFAAGEDCCVVETRLGRLGLMICYDNEFPEVARALATQGAQVILSPTANMVPNAERQALQ
EEECCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHH
IRARALDNQCFVACINRAGEEAELHYCGNSLIAGPDGEVLGRLGDAAGSLVVDIDLSRID
HHHHHHCCHHHHHHHHHCCCCCEEEECCCCEECCCCHHHHHHHHHCCCCEEEEEEHHHHH
ASRAHQDYLQDLRPMPETIA
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKLMLAQTDPVCGDVAANLASLARQCQQAVAAGADLLVLPELALSGYNIFERLEELAEPV
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCHHHHHHHHHHHHHC
GGPIAQRAAELAAEHELFLLFGLAERQADGRLTNSAVLIDDRGERIATYHKRQLWDREHA
CCHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
FFAAGEDCCVVETRLGRLGLMICYDNEFPEVARALATQGAQVILSPTANMVPNAERQALQ
EEECCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHH
IRARALDNQCFVACINRAGEEAELHYCGNSLIAGPDGEVLGRLGDAAGSLVVDIDLSRID
HHHHHHCCHHHHHHHHHCCCCCEEEECCCCEECCCCHHHHHHHHHCCCCEEEEEEHHHHH
ASRAHQDYLQDLRPMPETIA
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8526497 [H]