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The map label for this gene is codB [C]

Identifier: 92114958

GI number: 92114958

Start: 3172496

End: 3173830

Strand: Direct

Name: codB [C]

Synonym: Csal_2841

Alternate gene names: 92114958

Gene position: 3172496-3173830 (Clockwise)

Preceding gene: 92114957

Following gene: 92114959

Centisome position: 85.82

GC content: 65.47

Gene sequence:

>1335_bases
ATGGCTTTCTTCCATCGTCTGCTCGGTCAGGACACCCTCGACGACCACCAGCACAAGAGCCTCGGGGCGTTCGGCACTGT
CGCCCTGTGGCTCGGCGCCAACGTCGTGGTCACCACCATCCTCACCGGCATGCTCCTGGTGCCCGATCTGCCCTTCACGA
CCGCCATGGGCAGCGTGCTGATCGGCTCGTTGATCGGCGCCATCCCGCTCCTGCTGGTCGGGCTGATGGGCCAGCGCACC
GGCCTGCCTTCCATGGCGTTGACCCGGCGCGCGTATGGCCCGCTCGGCAGCCGGCTGATCTCGCTGGTCAACATGGGGGT
ACTGATCGCCTGGAGCTGGATCCAGGCCCTGCTCGCCGGCATGAGTCTCGACTACGCCATCCAGGCGACCACCGGCTACT
CCAACCTGCCCTTGATGACCATCCTCTGCGAGACCGTGGTGGTCCTCATCGTGCTGCGTGGCCACCTGGGCATCGAGCGG
GTCGAACGCTGGGCGGCGATGGCCATGGTGGCGCTGGCCGCCGTGGTGCTCTACCAGCTGAACCTCCACTACGATGTCTC
GACCCTGCTGGACATGCCGGTCGAGGCCCGTAACGGCATCACCCTGGGCATCGCCTTCGACATCGTCATCGCCACCGCCT
TCTCCTGGATCTCGTCCTCGGCGGATTACAATCGCAACTGCAAGAGCGGCGCCATCGCCGTCTGGGGCACCTACCTTGGC
TACGTGATGGCCGCCATGATCGCCATGGGCCTGGGTGCCGCCGTTTCCGGGCTGTCGGTCATGAACGGCATGGAGCAGAC
CTACGACCCGACCCGGCTGCTCTCCGGTTTCGGCTTCGGCCTGCCCGCGGCCCTGGTCATCTTCTTCTCCGTGATGACCA
CCAATGTCATGGCCGTCTACAGCGCCACCCTGTCCTGCATGAACGTGTCGCCCGGCATGGCCTTCTGGAAACCGGCGCTG
ATCATCGGGATCGTGACCGTCTTCGGCGCCCTGATTCCCGGCATCCTGGACCAGTTCCAGAACTTTCTGCTATTGATAGG
CGCGCTGTTCATCCCGGCCTTCTCGGTGATCATCGTCGATTACTACCTGGTCGGTCGCGAGGGTTACAGCCCCGAACTGC
TCAAGGCGCGTCACCAGCTGGGACGCCCCACCGCGCCGGTGGCCATCGGTGCCTACGTGATCGGCGCCGGGCTAGCCGCC
TACTGGTCGCTGGTCGCGCCGCTGGCCTTCGGCGCCTCGCTGCCGGTCTTCATCATCACCGGCGGCCTCTACTGGCTCGG
CGCCATGCTGTTGACAAAGTCCCGCGCCAACGCTTCACAGACCGCAGGAGAGTGA

Upstream 100 bases:

>100_bases
ACGCCGAACGCTGGCAGGCGGCACTCGACTGAGACGCCAACCGCGTCCCGAGAGCCGTCTCGGAAACAACGGTTTTCCAA
AACACTACAAGGACAACACC

Downstream 100 bases:

>100_bases
CACCGATGAAACTGATGCTGGCGCAGACCGACCCCGTGTGCGGCGACGTGGCCGCCAACCTGGCGTCTCTTGCGCGCCAG
TGCCAGCAGGCGGTGGCGGC

Product: permease for cytosine/purines, uracil, thiamine, allantoin

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: ORF 5 [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAFFHRLLGQDTLDDHQHKSLGAFGTVALWLGANVVVTTILTGMLLVPDLPFTTAMGSVLIGSLIGAIPLLLVGLMGQRT
GLPSMALTRRAYGPLGSRLISLVNMGVLIAWSWIQALLAGMSLDYAIQATTGYSNLPLMTILCETVVVLIVLRGHLGIER
VERWAAMAMVALAAVVLYQLNLHYDVSTLLDMPVEARNGITLGIAFDIVIATAFSWISSSADYNRNCKSGAIAVWGTYLG
YVMAAMIAMGLGAAVSGLSVMNGMEQTYDPTRLLSGFGFGLPAALVIFFSVMTTNVMAVYSATLSCMNVSPGMAFWKPAL
IIGIVTVFGALIPGILDQFQNFLLLIGALFIPAFSVIIVDYYLVGREGYSPELLKARHQLGRPTAPVAIGAYVIGAGLAA
YWSLVAPLAFGASLPVFIITGGLYWLGAMLLTKSRANASQTAGE

Sequences:

>Translated_444_residues
MAFFHRLLGQDTLDDHQHKSLGAFGTVALWLGANVVVTTILTGMLLVPDLPFTTAMGSVLIGSLIGAIPLLLVGLMGQRT
GLPSMALTRRAYGPLGSRLISLVNMGVLIAWSWIQALLAGMSLDYAIQATTGYSNLPLMTILCETVVVLIVLRGHLGIER
VERWAAMAMVALAAVVLYQLNLHYDVSTLLDMPVEARNGITLGIAFDIVIATAFSWISSSADYNRNCKSGAIAVWGTYLG
YVMAAMIAMGLGAAVSGLSVMNGMEQTYDPTRLLSGFGFGLPAALVIFFSVMTTNVMAVYSATLSCMNVSPGMAFWKPAL
IIGIVTVFGALIPGILDQFQNFLLLIGALFIPAFSVIIVDYYLVGREGYSPELLKARHQLGRPTAPVAIGAYVIGAGLAA
YWSLVAPLAFGASLPVFIITGGLYWLGAMLLTKSRANASQTAGE
>Mature_443_residues
AFFHRLLGQDTLDDHQHKSLGAFGTVALWLGANVVVTTILTGMLLVPDLPFTTAMGSVLIGSLIGAIPLLLVGLMGQRTG
LPSMALTRRAYGPLGSRLISLVNMGVLIAWSWIQALLAGMSLDYAIQATTGYSNLPLMTILCETVVVLIVLRGHLGIERV
ERWAAMAMVALAAVVLYQLNLHYDVSTLLDMPVEARNGITLGIAFDIVIATAFSWISSSADYNRNCKSGAIAVWGTYLGY
VMAAMIAMGLGAAVSGLSVMNGMEQTYDPTRLLSGFGFGLPAALVIFFSVMTTNVMAVYSATLSCMNVSPGMAFWKPALI
IGIVTVFGALIPGILDQFQNFLLLIGALFIPAFSVIIVDYYLVGREGYSPELLKARHQLGRPTAPVAIGAYVIGAGLAAY
WSLVAPLAFGASLPVFIITGGLYWLGAMLLTKSRANASQTAGE

Specific function: Required For Cytosine Transport Into The Cell. [C]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 47141; Mature: 47009

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFFHRLLGQDTLDDHQHKSLGAFGTVALWLGANVVVTTILTGMLLVPDLPFTTAMGSVL
CHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
IGSLIGAIPLLLVGLMGQRTGLPSMALTRRAYGPLGSRLISLVNMGVLIAWSWIQALLAG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
MSLDYAIQATTGYSNLPLMTILCETVVVLIVLRGHLGIERVERWAAMAMVALAAVVLYQL
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
NLHYDVSTLLDMPVEARNGITLGIAFDIVIATAFSWISSSADYNRNCKSGAIAVWGTYLG
HCCCCHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
YVMAAMIAMGLGAAVSGLSVMNGMEQTYDPTRLLSGFGFGLPAALVIFFSVMTTNVMAVY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SATLSCMNVSPGMAFWKPALIIGIVTVFGALIPGILDQFQNFLLLIGALFIPAFSVIIVD
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYLVGREGYSPELLKARHQLGRPTAPVAIGAYVIGAGLAAYWSLVAPLAFGASLPVFIIT
HHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GGLYWLGAMLLTKSRANASQTAGE
HHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AFFHRLLGQDTLDDHQHKSLGAFGTVALWLGANVVVTTILTGMLLVPDLPFTTAMGSVL
HHHHHHHCCCCCCHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
IGSLIGAIPLLLVGLMGQRTGLPSMALTRRAYGPLGSRLISLVNMGVLIAWSWIQALLAG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
MSLDYAIQATTGYSNLPLMTILCETVVVLIVLRGHLGIERVERWAAMAMVALAAVVLYQL
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
NLHYDVSTLLDMPVEARNGITLGIAFDIVIATAFSWISSSADYNRNCKSGAIAVWGTYLG
HCCCCHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
YVMAAMIAMGLGAAVSGLSVMNGMEQTYDPTRLLSGFGFGLPAALVIFFSVMTTNVMAVY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SATLSCMNVSPGMAFWKPALIIGIVTVFGALIPGILDQFQNFLLLIGALFIPAFSVIIVD
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYLVGREGYSPELLKARHQLGRPTAPVAIGAYVIGAGLAAYWSLVAPLAFGASLPVFIIT
HHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GGLYWLGAMLLTKSRANASQTAGE
HHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]