Click here to switch to the map view.

The map label for this gene is dctD [H]

Identifier: 92114525

GI number: 92114525

Start: 2701315

End: 2702700

Strand: Direct

Name: dctD [H]

Synonym: Csal_2407

Alternate gene names: 92114525

Gene position: 2701315-2702700 (Clockwise)

Preceding gene: 92114524

Following gene: 92114526

Centisome position: 73.07

GC content: 65.73

Gene sequence:

>1386_bases
ATGCATGACCCTGCTGCTACGCCCGTGATGCTCGTCGACGATGAAGCTCACTTGCGCATTACCGCCAGCCAGACCCTCGA
ACTGGCGGGCTACGTACCCGAGGTCTACGAAAGCGCCGAGGCGGCGCTGAGTGCCCTGCGGGCGGATTTCCCCGGCGTGC
TGGTCAGCGACATCCGCATGCCCGGCATGGACGGCATGGCCCTGCTGCGCGAAATTCGTCAGCGCGATCCCGACCTGCCC
GTGGTACTGATCACCGGCCACGGCGACATTTCCACGGCCGTGGAAGCCATGCGCGATGGCGCCTGGGATTTCCTCGAGAA
GCCCTTCGCCGGGGAGCGGCTGGTGGAGGTGGTGCGGCGGGGCATCGAAAAACGCCGCTTGAGCCTGGAGAACCGGCATC
TGAAGGCCGAACTCGAGGCGCAGCAGTCCACCCCGGGGCCTCGCCTGGTCGGCCGGACGCCGGCCATTCAGCAACTGGCC
TCGATGGTCCAGCGCATCAGCCAGGTCGAGACCGACGTGCTGCTCTTCGGCGAGACCGGTACAGGCAAGGATCTGGTGGC
ACGGGCGATTCACGAGCGCAGCGCCCGCGGCGGCAAGCCGTTCGTCGCCATCAATTGCGGCGCGGTGCCGGAAAGCACGA
TCGAGTCGGAACTCTTCGGCCATGAAAAGGGGGCCTTCACCGGGGCCGTGGAACGCCGCGTGGGGAAGTTCGAACACGCC
AACGGCGGGACCGTCTTCCTCGACGAGATCGAATCGATGCCGCTGTCGCTTCAGGTCAAGCTGCTGCGCGTGCTGCAGGA
ACGCGCCGTGGAACGCCTGGGCTCCAACACCCTGATCCCGCTCGACATCCGGGTCATCGCCGCGACCAAGACGGATCTCA
AGGCGGCCGCCGACACCGGCGGGTTCCGGGAGGACCTTTACTATCGTCTCAACGTCGTGACCCTGCCGATTCCCTCGCTG
CGCGAGCGTCGTGAGGATATTCCGCTGCTGTTCCAGCACTTCATCGCGGTCTCCGCCAGTCGCAGCGGACTGGAAGCCCC
GCCGCTCGATGGTCATGGGATCTCCGCCCTGCTCGCTCACGACTGGCCGGGCAACGTGCGCGAATTGCGCAACGTGGCCG
AGCGCTATGTGCTGCTGGGCGCCACCTGCGATTACCGACTCGAGACCCTGCTCCAGGGCGCGCAGAAGGACAGCGGCGAG
CTGCCCCTGGCGCAGCAGGTGGAGCTGTTCGAAAAGAGCGTGATCAACCATGCCCTGGTGCGCTATCAGGGGTGCGTGCC
GGATATCTGCGAGCGACTCGGCGTGCCGCGCAAGACGCTGTACGACAAGCTCAAGAAGCATGGACTGAAGGCCGACGACT
ATCGCCATATCGCGGAAACGGAATGA

Upstream 100 bases:

>100_bases
CTCGACGCCTGCAACTTGCCCGGCGGCGGCGCACGCTTTCGTGTCCGGCTGCCGCGTATCGCGGATCCCAACGATCCCGC
ACGACTCGAGGACCCCGCTC

Downstream 100 bases:

>100_bases
CCGGCCCTCGCCCTCGATGGGCGTCGACGCGTTGTGCGGAAATCCGCACAGGGTTCAGGCCAGGTTGTGCGAACTTCCAG
CCACATCGGCATGCTCCCTC

Product: two component, sigma54 specific, Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MHDPAATPVMLVDDEAHLRITASQTLELAGYVPEVYESAEAALSALRADFPGVLVSDIRMPGMDGMALLREIRQRDPDLP
VVLITGHGDISTAVEAMRDGAWDFLEKPFAGERLVEVVRRGIEKRRLSLENRHLKAELEAQQSTPGPRLVGRTPAIQQLA
SMVQRISQVETDVLLFGETGTGKDLVARAIHERSARGGKPFVAINCGAVPESTIESELFGHEKGAFTGAVERRVGKFEHA
NGGTVFLDEIESMPLSLQVKLLRVLQERAVERLGSNTLIPLDIRVIAATKTDLKAAADTGGFREDLYYRLNVVTLPIPSL
RERREDIPLLFQHFIAVSASRSGLEAPPLDGHGISALLAHDWPGNVRELRNVAERYVLLGATCDYRLETLLQGAQKDSGE
LPLAQQVELFEKSVINHALVRYQGCVPDICERLGVPRKTLYDKLKKHGLKADDYRHIAETE

Sequences:

>Translated_461_residues
MHDPAATPVMLVDDEAHLRITASQTLELAGYVPEVYESAEAALSALRADFPGVLVSDIRMPGMDGMALLREIRQRDPDLP
VVLITGHGDISTAVEAMRDGAWDFLEKPFAGERLVEVVRRGIEKRRLSLENRHLKAELEAQQSTPGPRLVGRTPAIQQLA
SMVQRISQVETDVLLFGETGTGKDLVARAIHERSARGGKPFVAINCGAVPESTIESELFGHEKGAFTGAVERRVGKFEHA
NGGTVFLDEIESMPLSLQVKLLRVLQERAVERLGSNTLIPLDIRVIAATKTDLKAAADTGGFREDLYYRLNVVTLPIPSL
RERREDIPLLFQHFIAVSASRSGLEAPPLDGHGISALLAHDWPGNVRELRNVAERYVLLGATCDYRLETLLQGAQKDSGE
LPLAQQVELFEKSVINHALVRYQGCVPDICERLGVPRKTLYDKLKKHGLKADDYRHIAETE
>Mature_461_residues
MHDPAATPVMLVDDEAHLRITASQTLELAGYVPEVYESAEAALSALRADFPGVLVSDIRMPGMDGMALLREIRQRDPDLP
VVLITGHGDISTAVEAMRDGAWDFLEKPFAGERLVEVVRRGIEKRRLSLENRHLKAELEAQQSTPGPRLVGRTPAIQQLA
SMVQRISQVETDVLLFGETGTGKDLVARAIHERSARGGKPFVAINCGAVPESTIESELFGHEKGAFTGAVERRVGKFEHA
NGGTVFLDEIESMPLSLQVKLLRVLQERAVERLGSNTLIPLDIRVIAATKTDLKAAADTGGFREDLYYRLNVVTLPIPSL
RERREDIPLLFQHFIAVSASRSGLEAPPLDGHGISALLAHDWPGNVRELRNVAERYVLLGATCDYRLETLLQGAQKDSGE
LPLAQQVELFEKSVINHALVRYQGCVPDICERLGVPRKTLYDKLKKHGLKADDYRHIAETE

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=460, Percent_Identity=41.304347826087, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1790299, Length=470, Percent_Identity=40.4255319148936, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI1790437, Length=443, Percent_Identity=42.6636568848758, Blast_Score=328, Evalue=4e-91,
Organism=Escherichia coli, GI1788905, Length=458, Percent_Identity=40.8296943231441, Blast_Score=315, Evalue=6e-87,
Organism=Escherichia coli, GI1789087, Length=333, Percent_Identity=44.4444444444444, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI87082117, Length=319, Percent_Identity=44.2006269592476, Blast_Score=244, Evalue=8e-66,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=41.875, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI87082152, Length=339, Percent_Identity=38.3480825958702, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1786524, Length=322, Percent_Identity=40.9937888198758, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1787583, Length=320, Percent_Identity=38.4375, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI87081872, Length=246, Percent_Identity=41.4634146341463, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI87081858, Length=291, Percent_Identity=32.6460481099656, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1789828, Length=231, Percent_Identity=36.7965367965368, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50854; Mature: 50854

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDPAATPVMLVDDEAHLRITASQTLELAGYVPEVYESAEAALSALRADFPGVLVSDIRM
CCCCCCCCEEEECCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCC
PGMDGMALLREIRQRDPDLPVVLITGHGDISTAVEAMRDGAWDFLEKPFAGERLVEVVRR
CCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHH
GIEKRRLSLENRHLKAELEAQQSTPGPRLVGRTPAIQQLASMVQRISQVETDVLLFGETG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCC
TGKDLVARAIHERSARGGKPFVAINCGAVPESTIESELFGHEKGAFTGAVERRVGKFEHA
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
NGGTVFLDEIESMPLSLQVKLLRVLQERAVERLGSNTLIPLDIRVIAATKTDLKAAADTG
CCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHCCC
GFREDLYYRLNVVTLPIPSLRERREDIPLLFQHFIAVSASRSGLEAPPLDGHGISALLAH
CCHHHHEEEEEEEEECCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEC
DWPGNVRELRNVAERYVLLGATCDYRLETLLQGAQKDSGELPLAQQVELFEKSVINHALV
CCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RYQGCVPDICERLGVPRKTLYDKLKKHGLKADDYRHIAETE
HHCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHCCCC
>Mature Secondary Structure
MHDPAATPVMLVDDEAHLRITASQTLELAGYVPEVYESAEAALSALRADFPGVLVSDIRM
CCCCCCCCEEEECCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCC
PGMDGMALLREIRQRDPDLPVVLITGHGDISTAVEAMRDGAWDFLEKPFAGERLVEVVRR
CCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHH
GIEKRRLSLENRHLKAELEAQQSTPGPRLVGRTPAIQQLASMVQRISQVETDVLLFGETG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCC
TGKDLVARAIHERSARGGKPFVAINCGAVPESTIESELFGHEKGAFTGAVERRVGKFEHA
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
NGGTVFLDEIESMPLSLQVKLLRVLQERAVERLGSNTLIPLDIRVIAATKTDLKAAADTG
CCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHCCC
GFREDLYYRLNVVTLPIPSLRERREDIPLLFQHFIAVSASRSGLEAPPLDGHGISALLAH
CCHHHHEEEEEEEEECCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEC
DWPGNVRELRNVAERYVLLGATCDYRLETLLQGAQKDSGELPLAQQVELFEKSVINHALV
CCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RYQGCVPDICERLGVPRKTLYDKLKKHGLKADDYRHIAETE
HHCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]