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The map label for this gene is dctB [H]

Identifier: 92114524

GI number: 92114524

Start: 2699364

End: 2701322

Strand: Direct

Name: dctB [H]

Synonym: Csal_2406

Alternate gene names: 92114524

Gene position: 2699364-2701322 (Clockwise)

Preceding gene: 92114523

Following gene: 92114525

Centisome position: 73.02

GC content: 66.62

Gene sequence:

>1959_bases
ATGGCCCCGATGCGTCATGCCATTTGCCACGAGCCGCTCGTCTTCATGTCCGATACACGCCGTTTCCCCCTTCCCGTGCG
GCCGCGCACGCTGCTCGTGCTGGCCGCGATCGCCGGCCTGCTCGTCTGCATGTGGCAGACGGCACGCCTGGCCCGTGAGC
AGGCGCTGCAGGAGCTGCGCCACGATGCCGAGAACGAACTGCGTCTGTCGGCTGCGAGCCTCGTCGGTCATCTCTCGCGT
CACGATTATCTGCCGGAACTGCTAGCCTCGCGGGAAATGGTCAAGCGCTTCCTGAACGACCCCGACGGGCAGGACTCGAT
GCCCTTGAATCGCCTGCTGGATCGCTTTCGCGCCACCGCCAACGTCTCCGACATCTACCTGCTCGATCATACCGGCGAAA
CCCTGGCGGCCAGCAACTGGCATCGTCGCGATACCTTCATCGGGCAGAACTACGGCTTCAGACCCTACTACCGGGAAGCC
ATGGACGGCAAGAACGGCAGTTTCTACGGCCTGGGCACCCAGTCGCGGGATCGCGGCTACTACTTCTCGGCCCCGGTGTG
GCTCGACGACACGGCGCCGAACGCGCGCCCGGACGGTGTCATGGTGCTCAAGGTCCTGCTCGATGCGGTGGAAGCCGGAT
GGGCCGAGCAGGACGCGGAGCTTCTGGTCACCGACCGCAATGGCGTCATCTTCATGGCCAGCCGGCCCGAATTGCGTTTG
ACCACCATGGCGCCGCTGACTCGGGCACAACGTCAGACCATCGCCGCCTCTCGGCGCTACGGCGATGCCCCGCTGCCGCC
AGCGGGCCTGCGCGAGGACCAGCGACACGATGCCCGCACACGCCTGGTGAGCTTCGCCTCCGGTTCCCTGGAAGGCAGGC
GTTATCTGAGCCTGACGCGCCCCATGGAAGATTTCGATTGGCACATTCACATCCTCAAGCCGCTGACGCCGGTCAATCAG
GCGCAGTGGCTGGCGGCGCTGCTTGCCGGCGGTCTCTACGGGCTCATCGCCCTGGGGGCCGGGATCGGATGGCAGCGCCT
GCGTCTGCGACGTGAGCGCGAGCGCTTCGCCGAACGCGAGCGACGCACCCTCGCCCAGGCCCGCGACGAACTCGAACGGC
ACGTGGAAAGCCGTACCCGTGACCTGGTCGCCACCAATCGGCGTCTGTCGGCGGAGATCGAGGAACGCCGCCGCGCCGAG
GAAAGCCTGCGCGCCACCCGCGACGAGCTGGTGCAAGCCGCCAAGCTGGCCGTGCTCGGGCAACTGGCGGCGGGCATCAA
TCACGAGCTCAACCAGCCCTTGGCGGCGATTCGTGCCTACACCGAGAATGCTCGCGCCTTCATCGCCCGCCAGCGACACG
AGGCCGCCGATGCCAACCTCGCCCAGGTACTCGAGCTGACCGAGCGCATGGCCGAGATCAGCGCGCAGCTGCGCCAGTTC
TCGCGCAAGAGCGGCGACAACCTGACGGCGGTTTCCGTCGCGTCGTGCTTTGCGTATGCATTGCGCCTGTTTCAGTCGCG
GATTCACGAAAGCGGCGTGCGGGTCGAGCAGCACTGGCCCGAGCAGGCGGTGTGGGTACGCGCCGACCCGGTGCGCCTCG
AGCAGGTGCTGGTCAACCTGATCGGCAACGCGCTCCAGGCCATGAACGATACCGCCGCCCCTTGCCTGACCCTCGCCATC
GTTGCCGAATCCACGACCGTGTACCTGGATGTCGCCGACAATGGCCCCGGCATCGACGAGGCACGCCTGGCCCAGATCTT
CGAACCGTTCTATACCACCAAGTCGATGGGCAGCGGCTTGGGGTTGGGCCTGTCGATCTCGCGACGTATCGTCGAGGATC
TCGATGGCCAGCTCGACGCCTGCAACTTGCCCGGCGGCGGCGCACGCTTTCGTGTCCGGCTGCCGCGTATCGCGGATCCC
AACGATCCCGCACGACTCGAGGACCCCGCTCATGCATGA

Upstream 100 bases:

>100_bases
CTCAGCACTCAAGCAATCGGCGCTCGGGACCGCGACTAAAGACTAAGCGCTGGCGCTTAACTTTAGACAAACCGCCACGC
ATCATGATGCGTGTGGCCAT

Downstream 100 bases:

>100_bases
CCCTGCTGCTACGCCCGTGATGCTCGTCGACGATGAAGCTCACTTGCGCATTACCGCCAGCCAGACCCTCGAACTGGCGG
GCTACGTACCCGAGGTCTAC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 651

Protein sequence:

>652_residues
MAPMRHAICHEPLVFMSDTRRFPLPVRPRTLLVLAAIAGLLVCMWQTARLAREQALQELRHDAENELRLSAASLVGHLSR
HDYLPELLASREMVKRFLNDPDGQDSMPLNRLLDRFRATANVSDIYLLDHTGETLAASNWHRRDTFIGQNYGFRPYYREA
MDGKNGSFYGLGTQSRDRGYYFSAPVWLDDTAPNARPDGVMVLKVLLDAVEAGWAEQDAELLVTDRNGVIFMASRPELRL
TTMAPLTRAQRQTIAASRRYGDAPLPPAGLREDQRHDARTRLVSFASGSLEGRRYLSLTRPMEDFDWHIHILKPLTPVNQ
AQWLAALLAGGLYGLIALGAGIGWQRLRLRRERERFAERERRTLAQARDELERHVESRTRDLVATNRRLSAEIEERRRAE
ESLRATRDELVQAAKLAVLGQLAAGINHELNQPLAAIRAYTENARAFIARQRHEAADANLAQVLELTERMAEISAQLRQF
SRKSGDNLTAVSVASCFAYALRLFQSRIHESGVRVEQHWPEQAVWVRADPVRLEQVLVNLIGNALQAMNDTAAPCLTLAI
VAESTTVYLDVADNGPGIDEARLAQIFEPFYTTKSMGSGLGLGLSISRRIVEDLDGQLDACNLPGGGARFRVRLPRIADP
NDPARLEDPAHA

Sequences:

>Translated_652_residues
MAPMRHAICHEPLVFMSDTRRFPLPVRPRTLLVLAAIAGLLVCMWQTARLAREQALQELRHDAENELRLSAASLVGHLSR
HDYLPELLASREMVKRFLNDPDGQDSMPLNRLLDRFRATANVSDIYLLDHTGETLAASNWHRRDTFIGQNYGFRPYYREA
MDGKNGSFYGLGTQSRDRGYYFSAPVWLDDTAPNARPDGVMVLKVLLDAVEAGWAEQDAELLVTDRNGVIFMASRPELRL
TTMAPLTRAQRQTIAASRRYGDAPLPPAGLREDQRHDARTRLVSFASGSLEGRRYLSLTRPMEDFDWHIHILKPLTPVNQ
AQWLAALLAGGLYGLIALGAGIGWQRLRLRRERERFAERERRTLAQARDELERHVESRTRDLVATNRRLSAEIEERRRAE
ESLRATRDELVQAAKLAVLGQLAAGINHELNQPLAAIRAYTENARAFIARQRHEAADANLAQVLELTERMAEISAQLRQF
SRKSGDNLTAVSVASCFAYALRLFQSRIHESGVRVEQHWPEQAVWVRADPVRLEQVLVNLIGNALQAMNDTAAPCLTLAI
VAESTTVYLDVADNGPGIDEARLAQIFEPFYTTKSMGSGLGLGLSISRRIVEDLDGQLDACNLPGGGARFRVRLPRIADP
NDPARLEDPAHA
>Mature_651_residues
APMRHAICHEPLVFMSDTRRFPLPVRPRTLLVLAAIAGLLVCMWQTARLAREQALQELRHDAENELRLSAASLVGHLSRH
DYLPELLASREMVKRFLNDPDGQDSMPLNRLLDRFRATANVSDIYLLDHTGETLAASNWHRRDTFIGQNYGFRPYYREAM
DGKNGSFYGLGTQSRDRGYYFSAPVWLDDTAPNARPDGVMVLKVLLDAVEAGWAEQDAELLVTDRNGVIFMASRPELRLT
TMAPLTRAQRQTIAASRRYGDAPLPPAGLREDQRHDARTRLVSFASGSLEGRRYLSLTRPMEDFDWHIHILKPLTPVNQA
QWLAALLAGGLYGLIALGAGIGWQRLRLRRERERFAERERRTLAQARDELERHVESRTRDLVATNRRLSAEIEERRRAEE
SLRATRDELVQAAKLAVLGQLAAGINHELNQPLAAIRAYTENARAFIARQRHEAADANLAQVLELTERMAEISAQLRQFS
RKSGDNLTAVSVASCFAYALRLFQSRIHESGVRVEQHWPEQAVWVRADPVRLEQVLVNLIGNALQAMNDTAAPCLTLAIV
AESTTVYLDVADNGPGIDEARLAQIFEPFYTTKSMGSGLGLGLSISRRIVEDLDGQLDACNLPGGGARFRVRLPRIADPN
DPARLEDPAHA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=232, Percent_Identity=33.1896551724138, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=30.6451612903226, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=26.2172284644195, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87081816, Length=290, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1788393, Length=222, Percent_Identity=29.2792792792793, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=258, Percent_Identity=30.2325581395349, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=123, Percent_Identity=37.3983739837398, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789149, Length=297, Percent_Identity=22.2222222222222, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=302, Percent_Identity=22.8476821192053, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=282, Percent_Identity=25.886524822695, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=27.8761061946903, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789808, Length=222, Percent_Identity=25.2252252252252, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73124; Mature: 72993

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPMRHAICHEPLVFMSDTRRFPLPVRPRTLLVLAAIAGLLVCMWQTARLAREQALQELR
CCCHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDAENELRLSAASLVGHLSRHDYLPELLASREMVKRFLNDPDGQDSMPLNRLLDRFRATA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
NVSDIYLLDHTGETLAASNWHRRDTFIGQNYGFRPYYREAMDGKNGSFYGLGTQSRDRGY
CCCEEEEEECCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEECCCCCCCCCE
YFSAPVWLDDTAPNARPDGVMVLKVLLDAVEAGWAEQDAELLVTDRNGVIFMASRPELRL
EEECCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCEEE
TTMAPLTRAQRQTIAASRRYGDAPLPPAGLREDQRHDARTRLVSFASGSLEGRRYLSLTR
EHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECC
PMEDFDWHIHILKPLTPVNQAQWLAALLAGGLYGLIALGAGIGWQRLRLRRERERFAERE
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RRTLAQARDELERHVESRTRDLVATNRRLSAEIEERRRAEESLRATRDELVQAAKLAVLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAAGINHELNQPLAAIRAYTENARAFIARQRHEAADANLAQVLELTERMAEISAQLRQF
HHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SRKSGDNLTAVSVASCFAYALRLFQSRIHESGVRVEQHWPEQAVWVRADPVRLEQVLVNL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEECCHHHHHHHHHHH
IGNALQAMNDTAAPCLTLAIVAESTTVYLDVADNGPGIDEARLAQIFEPFYTTKSMGSGL
HHHHHHHHCCCCHHHHHHHEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCC
GLGLSISRRIVEDLDGQLDACNLPGGGARFRVRLPRIADPNDPARLEDPAHA
CCCHHHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
APMRHAICHEPLVFMSDTRRFPLPVRPRTLLVLAAIAGLLVCMWQTARLAREQALQELR
CCHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDAENELRLSAASLVGHLSRHDYLPELLASREMVKRFLNDPDGQDSMPLNRLLDRFRATA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
NVSDIYLLDHTGETLAASNWHRRDTFIGQNYGFRPYYREAMDGKNGSFYGLGTQSRDRGY
CCCEEEEEECCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEECCCCCCCCCE
YFSAPVWLDDTAPNARPDGVMVLKVLLDAVEAGWAEQDAELLVTDRNGVIFMASRPELRL
EEECCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCEEE
TTMAPLTRAQRQTIAASRRYGDAPLPPAGLREDQRHDARTRLVSFASGSLEGRRYLSLTR
EHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECC
PMEDFDWHIHILKPLTPVNQAQWLAALLAGGLYGLIALGAGIGWQRLRLRRERERFAERE
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RRTLAQARDELERHVESRTRDLVATNRRLSAEIEERRRAEESLRATRDELVQAAKLAVLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAAGINHELNQPLAAIRAYTENARAFIARQRHEAADANLAQVLELTERMAEISAQLRQF
HHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SRKSGDNLTAVSVASCFAYALRLFQSRIHESGVRVEQHWPEQAVWVRADPVRLEQVLVNL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEECCHHHHHHHHHHH
IGNALQAMNDTAAPCLTLAIVAESTTVYLDVADNGPGIDEARLAQIFEPFYTTKSMGSGL
HHHHHHHHCCCCHHHHHHHEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCC
GLGLSISRRIVEDLDGQLDACNLPGGGARFRVRLPRIADPNDPARLEDPAHA
CCCHHHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]