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The map label for this gene is queC

Identifier: 92114160

GI number: 92114160

Start: 2300087

End: 2300842

Strand: Direct

Name: queC

Synonym: Csal_2038

Alternate gene names: 92114160

Gene position: 2300087-2300842 (Clockwise)

Preceding gene: 92114159

Following gene: 92114161

Centisome position: 62.22

GC content: 64.15

Gene sequence:

>756_bases
ATGTCGGACCTTCCCCGTCATTCTCCCCGGCGCCAACACGCCGGGGAAAGCGCCGTTACCGCCATCACCTCGCCCGAAGA
CACCACCAAGGCCGTGGTCATCTATTCCGGCGGAATGGATTCCTACACCGTACTTCACCGCGCGCTGCGCGCCGGTTTCG
AGGTACACGCGCTGTCATTCCACTACGGTCAGCGCCACTCCCGCGAACTGGAAACCGCTCATGATGTCTGTCAGCGGCTC
GGCATCGCGCATCAAGTCGTCGATATCCGTGCCATTCACGGATTGATCGGCAACTCGGCCCTGACCGACGCCACCCAGAC
CATGCCCGACGGTGACTACGATGCCGATAACATGGCGGCCACGGTGGTTCCCAACCGCAACATGATCCTGCTATCGCTGG
CCATCGGCCATGCCGTCAATATCGGCGCCAACGTGTGTTTCTACGGCGCCCACGGCGGCGACCACGTGCTTTATCCGGAT
TGCCGCCCCGAGTTCGTCGAGCGGATGAACGATGTCGCGGCCATCGCCGACTTCACCCCCGTGCGCATCGCGGCGCCCTA
TCTGCACGCCAGCAAGGAAGAGATTCTCGCCGATGGCCTGGCGATGGGTCTCGACTACGCGCAGACCTGGACCTGCTATC
TCGGCGCCGAGCGCTCCTGCGGTCACTGCGGCAGCTGTCGTGAACGTCTCGCGGCCTTCGCCGCCCAGGGCGTGACGGAC
CCTCTGGTCTATGCCGGTGCGGGAGCCTCTGACTGA

Upstream 100 bases:

>100_bases
TACACTATGCGCGCTTCGTCCGGACCGGATCCCGGGCGTATTTCCCAGGCGTGCCACCACACGCTGGGCGCTATAAATTC
TCCGCTCAGGACAATGCCTC

Downstream 100 bases:

>100_bases
TGTACAGCGTCAAGGAAGCGTTCTATACCTTGCAGGGCGAAGGTGCACGCGCCGGACGGGCCAGCGTCTTCTGTCGCTTC
ACGGGGTGCAACCTCTGGTC

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSDLPRHSPRRQHAGESAVTAITSPEDTTKAVVIYSGGMDSYTVLHRALRAGFEVHALSFHYGQRHSRELETAHDVCQRL
GIAHQVVDIRAIHGLIGNSALTDATQTMPDGDYDADNMAATVVPNRNMILLSLAIGHAVNIGANVCFYGAHGGDHVLYPD
CRPEFVERMNDVAAIADFTPVRIAAPYLHASKEEILADGLAMGLDYAQTWTCYLGAERSCGHCGSCRERLAAFAAQGVTD
PLVYAGAGASD

Sequences:

>Translated_251_residues
MSDLPRHSPRRQHAGESAVTAITSPEDTTKAVVIYSGGMDSYTVLHRALRAGFEVHALSFHYGQRHSRELETAHDVCQRL
GIAHQVVDIRAIHGLIGNSALTDATQTMPDGDYDADNMAATVVPNRNMILLSLAIGHAVNIGANVCFYGAHGGDHVLYPD
CRPEFVERMNDVAAIADFTPVRIAAPYLHASKEEILADGLAMGLDYAQTWTCYLGAERSCGHCGSCRERLAAFAAQGVTD
PLVYAGAGASD
>Mature_250_residues
SDLPRHSPRRQHAGESAVTAITSPEDTTKAVVIYSGGMDSYTVLHRALRAGFEVHALSFHYGQRHSRELETAHDVCQRLG
IAHQVVDIRAIHGLIGNSALTDATQTMPDGDYDADNMAATVVPNRNMILLSLAIGHAVNIGANVCFYGAHGGDHVLYPDC
RPEFVERMNDVAAIADFTPVRIAAPYLHASKEEILADGLAMGLDYAQTWTCYLGAERSCGHCGSCRERLAAFAAQGVTDP
LVYAGAGASD

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=205, Percent_Identity=37.5609756097561, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_CHRSD (Q1QVW9)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_574088.1
- ProteinModelPortal:   Q1QVW9
- SMR:   Q1QVW9
- STRING:   Q1QVW9
- GeneID:   4025934
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2038
- NMPDR:   fig|290398.4.peg.1406
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK932708
- BioCyc:   CSAL290398:CSAL_2038-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26934; Mature: 26803

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLPRHSPRRQHAGESAVTAITSPEDTTKAVVIYSGGMDSYTVLHRALRAGFEVHALSF
CCCCCCCCCHHHHCCCHHEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEE
HYGQRHSRELETAHDVCQRLGIAHQVVDIRAIHGLIGNSALTDATQTMPDGDYDADNMAA
HHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEE
TVVPNRNMILLSLAIGHAVNIGANVCFYGAHGGDHVLYPDCRPEFVERMNDVAAIADFTP
EEECCCCEEEEEEECCCCEECCCEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHCCCC
VRIAAPYLHASKEEILADGLAMGLDYAQTWTCYLGAERSCGHCGSCRERLAAFAAQGVTD
CEEECHHHHCCHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
PLVYAGAGASD
CEEEECCCCCC
>Mature Secondary Structure 
SDLPRHSPRRQHAGESAVTAITSPEDTTKAVVIYSGGMDSYTVLHRALRAGFEVHALSF
CCCCCCCCHHHHCCCHHEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEE
HYGQRHSRELETAHDVCQRLGIAHQVVDIRAIHGLIGNSALTDATQTMPDGDYDADNMAA
HHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEE
TVVPNRNMILLSLAIGHAVNIGANVCFYGAHGGDHVLYPDCRPEFVERMNDVAAIADFTP
EEECCCCEEEEEEECCCCEECCCEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHCCCC
VRIAAPYLHASKEEILADGLAMGLDYAQTWTCYLGAERSCGHCGSCRERLAAFAAQGVTD
CEEECHHHHCCHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
PLVYAGAGASD
CEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA