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The map label for this gene is ansA [H]

Identifier: 92114159

GI number: 92114159

Start: 2298862

End: 2299902

Strand: Direct

Name: ansA [H]

Synonym: Csal_2037

Alternate gene names: 92114159

Gene position: 2298862-2299902 (Clockwise)

Preceding gene: 92114158

Following gene: 92114160

Centisome position: 62.19

GC content: 68.2

Gene sequence:

>1041_bases
ATGACGACTGCCAACACCATTCTTGTCCTGTATACCGGGGGCACCCTCGGCATGATCGAGAGCGCCCACGGCCTGCGCCC
CGCCGGCGACTTCGAAGCACGCCTGCGCCTGGCGATCTCGCGCTTGCCGGCCTCCCGTGGCGATGGCATTCCTCCCTTCG
AGATGCTCGAGTACGCAACGCCCATCGATTCGAGCAGCGCGACACCCGTCGACTGGCAGCGACTGGCACGGGATATCGCC
ACACGGCATGCCGACTACGCGGGATTCGTGGTTCTGCATGGCACCGACACGCTCGCCTGGACCGCCTCGAGTCTGGCCTT
CCAGCTGCAGGGCATCGACAAGCCAGTGGTCGTGACCGGCGCCCAGAAGCCGCTGGAAGCGCCAGGCAGCGATGCGCTGG
GCAACATCGAGACGGCCCTGCGCTTCGCGGCACTCCCCGGCCTTGCCGAAGTCACCGTCGCCTTCGCGGGCAAGCTCATG
CGCGGCTGCCGCAGCCGCAAATGGGACACCCACGCCTTCGACGGCTTTGCTTCGCCCAACTGGCCACTGCTGGGAGAATG
CATCGACGGCGCTCCGGTCTTGTACCCCTCTCGGCTGTTGTCGCCGAGCGGCGCACCCCGCTTCGAACTGCCCGATCTGT
CGACGACGTCGTCGGTCGTGCGCCTGGCGCTGTGGCCGGGCATCCAGGCCCGTCAGGTCGCGACCCTGCTCGACGAGGAC
AGCGTGCGGGGGGCCGTGCTCGAATGCTGGGGCAGCGGCAACATGCCCGACGACCCGCACCTGGCGGGGGCCCTGGTTAC
CGCCAGTGGCGCCGGCAAGCTATTGGCAGTGGTCAGCCAGTGCCCGCATGGGCCGGTGGCCCTGGAGACCTATGCCAGCG
GCCAGGCACTCGGTGATGCCGGCGTGCTGGCCGGCGACGACATGACCCCCGAGGCAGCCTTCACCAAGCTCACCCATGTC
CTGGCACAACCACTGACGGATGCACAGCGCCGTCATCGCTTCCTCAGCCCACTGTGCGGCGAACGCAGCGCGCTTGCATG
A

Upstream 100 bases:

>100_bases
CACGACCGACGCCCCCTCCCGCGGCTGGACGCTAGCCGACAAGGACGATAACTAGGTATCATCGCGCGCTCATTCGCTTG
CGTGCCGGGATGCCATCGCC

Downstream 100 bases:

>100_bases
CACGGTTCGCGGGCGCCGCCCGAGCCGCGCAGGAAGACGCGACGGCCTGATCCTCAACGACTAGCCGGCGAACGGTGTGC
CGGTTACACTATGCGCGCTT

Product: asparaginase

Products: NA

Alternate protein names: L-asparaginase I; L-ASNase I; L-asparagine amidohydrolase I [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTTANTILVLYTGGTLGMIESAHGLRPAGDFEARLRLAISRLPASRGDGIPPFEMLEYATPIDSSSATPVDWQRLARDIA
TRHADYAGFVVLHGTDTLAWTASSLAFQLQGIDKPVVVTGAQKPLEAPGSDALGNIETALRFAALPGLAEVTVAFAGKLM
RGCRSRKWDTHAFDGFASPNWPLLGECIDGAPVLYPSRLLSPSGAPRFELPDLSTTSSVVRLALWPGIQARQVATLLDED
SVRGAVLECWGSGNMPDDPHLAGALVTASGAGKLLAVVSQCPHGPVALETYASGQALGDAGVLAGDDMTPEAAFTKLTHV
LAQPLTDAQRRHRFLSPLCGERSALA

Sequences:

>Translated_346_residues
MTTANTILVLYTGGTLGMIESAHGLRPAGDFEARLRLAISRLPASRGDGIPPFEMLEYATPIDSSSATPVDWQRLARDIA
TRHADYAGFVVLHGTDTLAWTASSLAFQLQGIDKPVVVTGAQKPLEAPGSDALGNIETALRFAALPGLAEVTVAFAGKLM
RGCRSRKWDTHAFDGFASPNWPLLGECIDGAPVLYPSRLLSPSGAPRFELPDLSTTSSVVRLALWPGIQARQVATLLDED
SVRGAVLECWGSGNMPDDPHLAGALVTASGAGKLLAVVSQCPHGPVALETYASGQALGDAGVLAGDDMTPEAAFTKLTHV
LAQPLTDAQRRHRFLSPLCGERSALA
>Mature_345_residues
TTANTILVLYTGGTLGMIESAHGLRPAGDFEARLRLAISRLPASRGDGIPPFEMLEYATPIDSSSATPVDWQRLARDIAT
RHADYAGFVVLHGTDTLAWTASSLAFQLQGIDKPVVVTGAQKPLEAPGSDALGNIETALRFAALPGLAEVTVAFAGKLMR
GCRSRKWDTHAFDGFASPNWPLLGECIDGAPVLYPSRLLSPSGAPRFELPDLSTTSSVVRLALWPGIQARQVATLLDEDS
VRGAVLECWGSGNMPDDPHLAGALVTASGAGKLLAVVSQCPHGPVALETYASGQALGDAGVLAGDDMTPEAAFTKLTHVL
AQPLTDAQRRHRFLSPLCGERSALA

Specific function: Unknown

COG id: COG0252

COG function: function code EJ; L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the asparaginase 1 family [H]

Homologues:

Organism=Homo sapiens, GI122937331, Length=348, Percent_Identity=36.4942528735632, Blast_Score=157, Evalue=9e-39,
Organism=Escherichia coli, GI1788065, Length=339, Percent_Identity=39.2330383480826, Blast_Score=211, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI193207372, Length=362, Percent_Identity=35.9116022099448, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17558280, Length=360, Percent_Identity=36.1111111111111, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17558278, Length=360, Percent_Identity=36.1111111111111, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI193207374, Length=360, Percent_Identity=36.1111111111111, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24645530, Length=349, Percent_Identity=35.243553008596, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24639609, Length=365, Percent_Identity=36.1643835616438, Blast_Score=182, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006033
- InterPro:   IPR006034
- InterPro:   IPR020827 [H]

Pfam domain/function: PF00710 Asparaginase [H]

EC number: =3.5.1.1 [H]

Molecular weight: Translated: 36413; Mature: 36282

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00917 ASN_GLN_ASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTANTILVLYTGGTLGMIESAHGLRPAGDFEARLRLAISRLPASRGDGIPPFEMLEYAT
CCCCCEEEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCC
PIDSSSATPVDWQRLARDIATRHADYAGFVVLHGTDTLAWTASSLAFQLQGIDKPVVVTG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEHHHHEEEEECCCCCEEEEC
AQKPLEAPGSDALGNIETALRFAALPGLAEVTVAFAGKLMRGCRSRKWDTHAFDGFASPN
CCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
WPLLGECIDGAPVLYPSRLLSPSGAPRFELPDLSTTSSVVRLALWPGIQARQVATLLDED
CCCHHHHCCCCCCCCHHHHCCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHHCCC
SVRGAVLECWGSGNMPDDPHLAGALVTASGAGKLLAVVSQCPHGPVALETYASGQALGDA
CCCCEEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCC
GVLAGDDMTPEAAFTKLTHVLAQPLTDAQRRHRFLSPLCGERSALA
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTANTILVLYTGGTLGMIESAHGLRPAGDFEARLRLAISRLPASRGDGIPPFEMLEYAT
CCCCEEEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCC
PIDSSSATPVDWQRLARDIATRHADYAGFVVLHGTDTLAWTASSLAFQLQGIDKPVVVTG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEHHHHEEEEECCCCCEEEEC
AQKPLEAPGSDALGNIETALRFAALPGLAEVTVAFAGKLMRGCRSRKWDTHAFDGFASPN
CCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
WPLLGECIDGAPVLYPSRLLSPSGAPRFELPDLSTTSSVVRLALWPGIQARQVATLLDED
CCCHHHHCCCCCCCCHHHHCCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHHCCC
SVRGAVLECWGSGNMPDDPHLAGALVTASGAGKLLAVVSQCPHGPVALETYASGQALGDA
CCCCEEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCC
GVLAGDDMTPEAAFTKLTHVLAQPLTDAQRRHRFLSPLCGERSALA
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]