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The map label for this gene is trpF

Identifier: 92113386

GI number: 92113386

Start: 1438795

End: 1439430

Strand: Direct

Name: trpF

Synonym: Csal_1260

Alternate gene names: 92113386

Gene position: 1438795-1439430 (Clockwise)

Preceding gene: 92113385

Following gene: 92113387

Centisome position: 38.92

GC content: 68.08

Gene sequence:

>636_bases
ATGACGTCGCCGATGCAGCGTACGCGCGTCAAGATCTGCGGCCTGACCCGGGAGGAGGACATCGACGCCGCGGTGGCGGC
GGGCGCCGATGCGCTGGGGTTCGTCCTGTGGCCGGGCAGCTCGCGGGCCATCGACGAAGCCCGGCTGGCGCGCCTGGCCG
CCCGCGTGCCGGCGTTCGTGACCCGGGTGGGGCTGTTCGTCGACCAGGCCGATGACGAGATTCGGCGCTACGCACGCCAC
CTGGATCTCGTGCAGCTCCACGGCAACGAATCCCCCGACGACTGCGCGCGTCTCGATACTCCCTGGATCAAGGCACTGCG
CATGCGCGACGGCATCGACCTGCATGCCGAGATGTCCCGTTACGATGCGGCGCGCGGTCTGCTGCTGGATGCCTACCGCC
CCGGCGTTCCCGGAGGCACCGGGGAGACCTTCGACTGGTCGCGAATCCCCGCAAACCTGGCAAAACCTGTTATTCTCGCG
GGAGGCTTGACGGCGGACAACGTCGCCGAAGCCATTCACCGGGTCCGGCCCTATGCCGTCGACGTCTCGGGAGGCGTCGA
GGCGGCAAAGGGTCTCAAGGATCCTGCGCGCATCCGGGCATTTCTGTCCCAAGTGTCCCATACCCAAGCCCCATAG

Upstream 100 bases:

>100_bases
TTCTCGGCGAGTGGACCGGGGAGCGCCGCCTGCCCGATAGCGAGTGGGCGCGAGCGCGGCGTCAGCGTCGTGTCCATCCG
CCGCGCCGGGAGGTGTCATC

Downstream 100 bases:

>100_bases
AGGTGTCATTCGTGACCAAGTTCAGCGACCTGACCCGAATGCCGGACGCCCAAGGCCATTTCGGCCCGCACGGTGGCCGG
TTCGTTTCGGAGACTCTGAG

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTSPMQRTRVKICGLTREEDIDAAVAAGADALGFVLWPGSSRAIDEARLARLAARVPAFVTRVGLFVDQADDEIRRYARH
LDLVQLHGNESPDDCARLDTPWIKALRMRDGIDLHAEMSRYDAARGLLLDAYRPGVPGGTGETFDWSRIPANLAKPVILA
GGLTADNVAEAIHRVRPYAVDVSGGVEAAKGLKDPARIRAFLSQVSHTQAP

Sequences:

>Translated_211_residues
MTSPMQRTRVKICGLTREEDIDAAVAAGADALGFVLWPGSSRAIDEARLARLAARVPAFVTRVGLFVDQADDEIRRYARH
LDLVQLHGNESPDDCARLDTPWIKALRMRDGIDLHAEMSRYDAARGLLLDAYRPGVPGGTGETFDWSRIPANLAKPVILA
GGLTADNVAEAIHRVRPYAVDVSGGVEAAKGLKDPARIRAFLSQVSHTQAP
>Mature_210_residues
TSPMQRTRVKICGLTREEDIDAAVAAGADALGFVLWPGSSRAIDEARLARLAARVPAFVTRVGLFVDQADDEIRRYARHL
DLVQLHGNESPDDCARLDTPWIKALRMRDGIDLHAEMSRYDAARGLLLDAYRPGVPGGTGETFDWSRIPANLAKPVILAG
GLTADNVAEAIHRVRPYAVDVSGGVEAAKGLKDPARIRAFLSQVSHTQAP

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family

Homologues:

Organism=Escherichia coli, GI87081863, Length=198, Percent_Identity=32.3232323232323, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320210, Length=215, Percent_Identity=33.0232558139535, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRPF_CHRSD (Q1QY43)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_573314.1
- ProteinModelPortal:   Q1QY43
- SMR:   Q1QY43
- STRING:   Q1QY43
- GeneID:   4027581
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1260
- NMPDR:   fig|290398.4.peg.1250
- eggNOG:   COG0135
- HOGENOM:   HBG554803
- OMA:   SKICGIT
- BioCyc:   CSAL290398:CSAL_1260-MONOMER
- HAMAP:   MF_00135_B
- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF00697 PRAI; SSF51366 RibP_bind_barrel

EC number: =5.3.1.24

Molecular weight: Translated: 22875; Mature: 22744

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPMQRTRVKICGLTREEDIDAAVAAGADALGFVLWPGSSRAIDEARLARLAARVPAFV
CCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
TRVGLFVDQADDEIRRYARHLDLVQLHGNESPDDCARLDTPWIKALRMRDGIDLHAEMSR
HHHHHHHHCCHHHHHHHHHHCCEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCHHHHHHH
YDAARGLLLDAYRPGVPGGTGETFDWSRIPANLAKPVILAGGLTADNVAEAIHRVRPYAV
HHHHCCHHHCCCCCCCCCCCCCCCCHHHCCHHHCCCEEEECCCCHHHHHHHHHHHCCEEE
DVSGGVEAAKGLKDPARIRAFLSQVSHTQAP
ECCCCHHHHHCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSPMQRTRVKICGLTREEDIDAAVAAGADALGFVLWPGSSRAIDEARLARLAARVPAFV
CCCHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
TRVGLFVDQADDEIRRYARHLDLVQLHGNESPDDCARLDTPWIKALRMRDGIDLHAEMSR
HHHHHHHHCCHHHHHHHHHHCCEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCHHHHHHH
YDAARGLLLDAYRPGVPGGTGETFDWSRIPANLAKPVILAGGLTADNVAEAIHRVRPYAV
HHHHCCHHHCCCCCCCCCCCCCCCCHHHCCHHHCCCEEEECCCCHHHHHHHHHHHCCEEE
DVSGGVEAAKGLKDPARIRAFLSQVSHTQAP
ECCCCHHHHHCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA