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The map label for this gene is trpB [H]

Identifier: 92113387

GI number: 92113387

Start: 1439442

End: 1440656

Strand: Direct

Name: trpB [H]

Synonym: Csal_1261

Alternate gene names: 92113387

Gene position: 1439442-1440656 (Clockwise)

Preceding gene: 92113386

Following gene: 92113388

Centisome position: 38.94

GC content: 65.51

Gene sequence:

>1215_bases
GTGACCAAGTTCAGCGACCTGACCCGAATGCCGGACGCCCAAGGCCATTTCGGCCCGCACGGTGGCCGGTTCGTTTCGGA
GACTCTGAGCTTCGCCCTGGAGGAGTTGGAGAAGGCCTACATGAGCCTTCGCGACGATGCCGACTTCCAGGCCGAATTCG
ACCGTGACCTGGCTCATTACGTGGGCCGCCCGTCTCCGCTGTATCACGCACAGCGATGGTCCCAGCAGCTCGGCGGTGCG
CAGATCTGGCTCAAGCGCGAGGATCTCAACCACACCGGGGCCCACAAGGTGAACAACACCATCGGCCAGGCGCTGCTCGC
CAAGAAGAGCGGCAAGCCTCGGGTCATCGCCGAAACCGGTGCCGGCCAGCATGGCGTGGCCACGGCCACCGTCGCCGCGC
GGCTGGGGCTCAAGTGCGAGATCTACATGGGGGCCGAGGACGTCGAGCGCCAGAAGCTCAACGTCTATCGCATGCGCCTG
CTGGGGGCCGAAGTGCATCCGGTCGAGTCCGGGTCGCGAACCCTCAAGGACGCCATGAACGAGGCGCTGCGCGACTGGGT
GACCAATGTCGACGATACCTTCTACATCATCGGTACCGTGGCCGGCCCGCATCCTTATCCGGCCATGGTGCGCGACTTCA
CGTCGGTGATCGGTCGCGAAGCGCGCGAGCAGAGCTTTGCTCAGATCGGTCGCCTGCCGGATGCCCTGGTGGCCTGTGTC
GGCGGCGGTTCCAATGCCATCGGCCTGTTCTATCCCTTCCTCGAGGACGAGGACGTGGCCATGTACGGTGTCGAAGCCGG
CGGCGACGGTGTCGAGACCGGGCGTCACGCCGCGCCGCTGACCGCCAATGCCCCCAGCGGGGTGCTGCATGGCAACCGGA
CCTACCTGATGTCCGACGAGGGGGGGCAGGTCTCGGATACGCACTCGATCTCTGCCGGGCTCGACTATCCTGGTGTCGGC
CCCGAGCATGCGCTGTGGAAGGATGTCGGCCGGGTTCAGTACGTGGCGGCCAACGACGACGCGGTTCTTGCCGCGTTCCG
CGAGCTGACGCGCGTCGAGGGTATTATGCCCGCGCTGGAGTCGGCCCATGCCCTGGCGCATGCCAAGGTTCTGGCACCGA
CCATGCGTCCCGACCAGCACATCATCGTCAATCTCTCCGGGCGTGGCGACAAGGACATCCACACGGTGGCCAAGATCGAC
GGTCTGGAATTCTAA

Upstream 100 bases:

>100_bases
CGGGAGGCGTCGAGGCGGCAAAGGGTCTCAAGGATCCTGCGCGCATCCGGGCATTTCTGTCCCAAGTGTCCCATACCCAA
GCCCCATAGAGGTGTCATTC

Downstream 100 bases:

>100_bases
GCGCTGGCGGAGACATGACTATGAATCGTATCGATAAACGCTTCGCGGCGCTCAAGTCTCAACAGCGCCGCGCGTTGATT
CCTTATATCACCGCGGGCGA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTKFSDLTRMPDAQGHFGPHGGRFVSETLSFALEELEKAYMSLRDDADFQAEFDRDLAHYVGRPSPLYHAQRWSQQLGGA
QIWLKREDLNHTGAHKVNNTIGQALLAKKSGKPRVIAETGAGQHGVATATVAARLGLKCEIYMGAEDVERQKLNVYRMRL
LGAEVHPVESGSRTLKDAMNEALRDWVTNVDDTFYIIGTVAGPHPYPAMVRDFTSVIGREAREQSFAQIGRLPDALVACV
GGGSNAIGLFYPFLEDEDVAMYGVEAGGDGVETGRHAAPLTANAPSGVLHGNRTYLMSDEGGQVSDTHSISAGLDYPGVG
PEHALWKDVGRVQYVAANDDAVLAAFRELTRVEGIMPALESAHALAHAKVLAPTMRPDQHIIVNLSGRGDKDIHTVAKID
GLEF

Sequences:

>Translated_404_residues
MTKFSDLTRMPDAQGHFGPHGGRFVSETLSFALEELEKAYMSLRDDADFQAEFDRDLAHYVGRPSPLYHAQRWSQQLGGA
QIWLKREDLNHTGAHKVNNTIGQALLAKKSGKPRVIAETGAGQHGVATATVAARLGLKCEIYMGAEDVERQKLNVYRMRL
LGAEVHPVESGSRTLKDAMNEALRDWVTNVDDTFYIIGTVAGPHPYPAMVRDFTSVIGREAREQSFAQIGRLPDALVACV
GGGSNAIGLFYPFLEDEDVAMYGVEAGGDGVETGRHAAPLTANAPSGVLHGNRTYLMSDEGGQVSDTHSISAGLDYPGVG
PEHALWKDVGRVQYVAANDDAVLAAFRELTRVEGIMPALESAHALAHAKVLAPTMRPDQHIIVNLSGRGDKDIHTVAKID
GLEF
>Mature_403_residues
TKFSDLTRMPDAQGHFGPHGGRFVSETLSFALEELEKAYMSLRDDADFQAEFDRDLAHYVGRPSPLYHAQRWSQQLGGAQ
IWLKREDLNHTGAHKVNNTIGQALLAKKSGKPRVIAETGAGQHGVATATVAARLGLKCEIYMGAEDVERQKLNVYRMRLL
GAEVHPVESGSRTLKDAMNEALRDWVTNVDDTFYIIGTVAGPHPYPAMVRDFTSVIGREAREQSFAQIGRLPDALVACVG
GGSNAIGLFYPFLEDEDVAMYGVEAGGDGVETGRHAAPLTANAPSGVLHGNRTYLMSDEGGQVSDTHSISAGLDYPGVGP
EHALWKDVGRVQYVAANDDAVLAAFRELTRVEGIMPALESAHALAHAKVLAPTMRPDQHIIVNLSGRGDKDIHTVAKIDG
LEF

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=385, Percent_Identity=54.5454545454545, Blast_Score=418, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321412, Length=385, Percent_Identity=58.4415584415584, Blast_Score=470, Evalue=1e-133,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43778; Mature: 43647

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKFSDLTRMPDAQGHFGPHGGRFVSETLSFALEELEKAYMSLRDDADFQAEFDRDLAHY
CCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VGRPSPLYHAQRWSQQLGGAQIWLKREDLNHTGAHKVNNTIGQALLAKKSGKPRVIAETG
CCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECC
AGQHGVATATVAARLGLKCEIYMGAEDVERQKLNVYRMRLLGAEVHPVESGSRTLKDAMN
CCCCCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
EALRDWVTNVDDTFYIIGTVAGPHPYPAMVRDFTSVIGREAREQSFAQIGRLPDALVACV
HHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEE
GGGSNAIGLFYPFLEDEDVAMYGVEAGGDGVETGRHAAPLTANAPSGVLHGNRTYLMSDE
CCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCEEEEECCC
GGQVSDTHSISAGLDYPGVGPEHALWKDVGRVQYVAANDDAVLAAFRELTRVEGIMPALE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
SAHALAHAKVLAPTMRPDQHIIVNLSGRGDKDIHTVAKIDGLEF
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TKFSDLTRMPDAQGHFGPHGGRFVSETLSFALEELEKAYMSLRDDADFQAEFDRDLAHY
CCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VGRPSPLYHAQRWSQQLGGAQIWLKREDLNHTGAHKVNNTIGQALLAKKSGKPRVIAETG
CCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECC
AGQHGVATATVAARLGLKCEIYMGAEDVERQKLNVYRMRLLGAEVHPVESGSRTLKDAMN
CCCCCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
EALRDWVTNVDDTFYIIGTVAGPHPYPAMVRDFTSVIGREAREQSFAQIGRLPDALVACV
HHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEE
GGGSNAIGLFYPFLEDEDVAMYGVEAGGDGVETGRHAAPLTANAPSGVLHGNRTYLMSDE
CCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCEEEEECCC
GGQVSDTHSISAGLDYPGVGPEHALWKDVGRVQYVAANDDAVLAAFRELTRVEGIMPALE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
SAHALAHAKVLAPTMRPDQHIIVNLSGRGDKDIHTVAKIDGLEF
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA