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The map label for this gene is aceE [H]

Identifier: 92112983

GI number: 92112983

Start: 955255

End: 957945

Strand: Direct

Name: aceE [H]

Synonym: Csal_0855

Alternate gene names: 92112983

Gene position: 955255-957945 (Clockwise)

Preceding gene: 92112982

Following gene: 92112984

Centisome position: 25.84

GC content: 62.32

Gene sequence:

>2691_bases
ATGAGTCTGGAGGCAAGAGAAGATCTCGATCCGATCGAAACCACGGAATGGCTGGATTCCTTGGCCTCGGTCATCGAGCA
TGAGGGCGAAGAACGTGCTCGGTATATCATGAGTCGCCTGGCGGACCGCCTGCGTCGCGATGGCTCTTCACCGCCGTTTT
CCGGGACCACGCCGCATCGCAATACCATCCCGATGCATCGTGAAGCCAAGATGCCCGGCGACATGTTCATCGAGCGCAAG
ATTCGCTCGGCCATTCGCTGGAACGCGATGGTGCAGGTGCTGCGCGCCAACAAGAAGCACAAGGGCCTGGGCGGTCACAT
TGCCAGCTACCAGTCCAGTGCGACCTTGTACGAAGTGGGCTTCAACCACTTCTTCCGCGCGGACAATGGCGATCACAAGG
GCGACCTGCTGTACATCCAGGGGCACGTGACGCCGGGCATCTATGCGCGTTCCTTCCTCGAAGGCCGCCTGACCGAAGAG
CAGATGGACAACTTCCGTCAGGAAGTCGACGGCGACGCGCTGCCGTCTTACCCCCACCCGTACCTGATGCCGGATTACTG
GCAGTTCCCCACGGTCTCCATGGGACTGGGGCCGATCCAGGCGATCTATCAGGCTCACGTGATGAAGTACCTGCATTCGC
GTGAACTCGAGGACATGAAGGACCGCAAGGTCTGGGCATTCCTGGGGGACGGCGAGTGCGACGAGCCCGAAACCCTCGGC
GCGCTGCATCTGGCCAGCCGTGAAAAGCTCGACAACCTGATCTTCGTCATCAACTGCAACCTGCAGCGTCTCGATGGCCC
GGTGCGTGGCAACTCGCGCATCATCGACGAGCTGGAAGGCGTCTTCCGCGGTGCCGGCTGGAACGTGATCAAGGTCGTGT
GGGGCGGTCAGTGGGACCCGCTGTTCGAGCAGGACGCCAACGGCATGCTGCAAAAGCGCATGGACGAGGCGGTCGACGGC
GAGTACCAGAACTACAAGGCTCAGGGCGGTGCCTACACCCGCGAGCATTTCTTCGGCAAGTACGAAGAAACCGCGGCGAT
GGTCAAGGACTACACCGACGAGCAGATCTTCCGTCTCAACCGGGGCGGCCACGACCCGCAGAAGGTCTATGCGGCCTACC
ATGAAGCGGTCAACAACGCGGGCAACCGTCCCACCGTGATCCTGGCGCACACCGTCAAGGGTTACGGCATGGGCGGCGGC
AGCGGCGAAGCCGACATGGAAGCCCACCAGATCAAGTCGATGGATACCGACGCCCTCAAGGCGTTCCGCGACCGGTTCGG
CATCCCGATCTCCGACAAGCAGATCGAAAGCGGCGATATTCCGTACTACAAGCCCGACGACGACAGCCCGGAGATGAAGT
ACCTGCATCTCCAGCGCGAGAAGCTCGGCGGCTTCTTGCCGGCACGCAAGAACGACTTCGAGGCGCTCGAGATCCCCGGG
CTCGACGACAAGATGTTCGCGTCCCAGCTCAAGGGCTCCGGCGACCGTGAAGTGTCCAGCACGATGTCCTTCGTGCGCGT
GCTCAACGGCTTGGTCAAGAACAAGCAGCTCGGCTCGCGGGTGGTGCCGATCATTCCCGACGAGGCGCGTACCTTCGGGA
TGGAGGGCATGTTCCGTCAGCTTGGCATCTACGCCGCCGAAGGCCAGAAGTACGAGCCGATGGATGCCGGTCAGATCATG
TACTACCGCGAGGATCAGAAAGGCCAGATTCTCGAGGAAGGCATCACCGAAGCCGGCTCCATGTCCGCGTGGATCGCGGC
GGCGACGGCGTACGCCAACCACCACCTGCCGCTGATTCCGTTCTACGTCTACTACTCGATGTTCGGCTATCAGCGTGTCG
GCGACCTGGTCTGGGCCGCCGGTGACCTGCAGGCGCGTGGCTTCATGATCGGCGGTACCGCCGGGCGTACCACCATCAAC
GGCGAAGGCCTGCAGCACCAGGACGGCCACAGCCATATCCTGATGTCGACCGTGCCGACCTGCCGTGCCTACGACCCGTG
CTATGGCCACGAGGTGGCGGTCATCCTGCAGGACGGGCTGAAGCGGATGTTCCAGGACAAGGAAAACTGCTTCTACTACC
TGACCGTGATGAACGAGAACTACCCGCACCCGGAAATGCCGGAGGGCAGCGAGGAAGGCATCGTTCGCGGCATGTATCGT
CTCTCGGAAGGCAAGAAGGACGGCCGCAAGAAACAGCCGCGCGTGCAGCTGTTGGGCAGCGGCACGATCCTGCGCGAAGT
CGAGGCCGCCGCCGAGATGCTGGCGGAAGAGCATGGCGTGGTCGCCGACGTGTGGAGCGTGACCAGCTTCAACGAGCTGC
GTCGCGAAGCGCTCGAATACGACCGCCTGCAGTTCCTCGACTACGATGAGAAGCGTGAGAAGCCGTGGGTGGTGCAGCAG
CTGGATAGCGCCGAAGGGCCGGTCGTCGCCTCGACCGACTACATGAAGCTCTACGCCGACCAGATCCGCGCCTGGGTACC
GAGCGACTTCCACGTGCTGGGGACCGATGGTTTCGGACGTTCCGACACGCGTGAAGCGCTGCGTCGTTTCTTCGAAGTCG
ACCGCTACTACGTCACCATTCAAGCGCTGCGCGCGCTGGCCAATCGCGGTGAGATCGACGTCAAGGTCGTCAACGATGCC
ATGAAGAAATACGGCATCGACCCCGCCAAGCCCAGCCCGCTGGTGTCTTGA

Upstream 100 bases:

>100_bases
GGCCCAAAGAAGGTCGCGCCCGCACTGAAGAGCGCCACAGGCCCCATCGCGATGCGTAGACGGGCCAACCGACATACATG
CTTCATTCGGAGAGACGTCT

Downstream 100 bases:

>100_bases
GCCCCGTTGATGCCCTGGACCGAAGGGTCCCATCAGGGTGCCGTCATCGCCTAGGGGCGGTGGCGGCCATGGCCAGATTG
CCTGGTCTGGTCGCGTCACC

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 896; Mature: 895

Protein sequence:

>896_residues
MSLEAREDLDPIETTEWLDSLASVIEHEGEERARYIMSRLADRLRRDGSSPPFSGTTPHRNTIPMHREAKMPGDMFIERK
IRSAIRWNAMVQVLRANKKHKGLGGHIASYQSSATLYEVGFNHFFRADNGDHKGDLLYIQGHVTPGIYARSFLEGRLTEE
QMDNFRQEVDGDALPSYPHPYLMPDYWQFPTVSMGLGPIQAIYQAHVMKYLHSRELEDMKDRKVWAFLGDGECDEPETLG
ALHLASREKLDNLIFVINCNLQRLDGPVRGNSRIIDELEGVFRGAGWNVIKVVWGGQWDPLFEQDANGMLQKRMDEAVDG
EYQNYKAQGGAYTREHFFGKYEETAAMVKDYTDEQIFRLNRGGHDPQKVYAAYHEAVNNAGNRPTVILAHTVKGYGMGGG
SGEADMEAHQIKSMDTDALKAFRDRFGIPISDKQIESGDIPYYKPDDDSPEMKYLHLQREKLGGFLPARKNDFEALEIPG
LDDKMFASQLKGSGDREVSSTMSFVRVLNGLVKNKQLGSRVVPIIPDEARTFGMEGMFRQLGIYAAEGQKYEPMDAGQIM
YYREDQKGQILEEGITEAGSMSAWIAAATAYANHHLPLIPFYVYYSMFGYQRVGDLVWAAGDLQARGFMIGGTAGRTTIN
GEGLQHQDGHSHILMSTVPTCRAYDPCYGHEVAVILQDGLKRMFQDKENCFYYLTVMNENYPHPEMPEGSEEGIVRGMYR
LSEGKKDGRKKQPRVQLLGSGTILREVEAAAEMLAEEHGVVADVWSVTSFNELRREALEYDRLQFLDYDEKREKPWVVQQ
LDSAEGPVVASTDYMKLYADQIRAWVPSDFHVLGTDGFGRSDTREALRRFFEVDRYYVTIQALRALANRGEIDVKVVNDA
MKKYGIDPAKPSPLVS

Sequences:

>Translated_896_residues
MSLEAREDLDPIETTEWLDSLASVIEHEGEERARYIMSRLADRLRRDGSSPPFSGTTPHRNTIPMHREAKMPGDMFIERK
IRSAIRWNAMVQVLRANKKHKGLGGHIASYQSSATLYEVGFNHFFRADNGDHKGDLLYIQGHVTPGIYARSFLEGRLTEE
QMDNFRQEVDGDALPSYPHPYLMPDYWQFPTVSMGLGPIQAIYQAHVMKYLHSRELEDMKDRKVWAFLGDGECDEPETLG
ALHLASREKLDNLIFVINCNLQRLDGPVRGNSRIIDELEGVFRGAGWNVIKVVWGGQWDPLFEQDANGMLQKRMDEAVDG
EYQNYKAQGGAYTREHFFGKYEETAAMVKDYTDEQIFRLNRGGHDPQKVYAAYHEAVNNAGNRPTVILAHTVKGYGMGGG
SGEADMEAHQIKSMDTDALKAFRDRFGIPISDKQIESGDIPYYKPDDDSPEMKYLHLQREKLGGFLPARKNDFEALEIPG
LDDKMFASQLKGSGDREVSSTMSFVRVLNGLVKNKQLGSRVVPIIPDEARTFGMEGMFRQLGIYAAEGQKYEPMDAGQIM
YYREDQKGQILEEGITEAGSMSAWIAAATAYANHHLPLIPFYVYYSMFGYQRVGDLVWAAGDLQARGFMIGGTAGRTTIN
GEGLQHQDGHSHILMSTVPTCRAYDPCYGHEVAVILQDGLKRMFQDKENCFYYLTVMNENYPHPEMPEGSEEGIVRGMYR
LSEGKKDGRKKQPRVQLLGSGTILREVEAAAEMLAEEHGVVADVWSVTSFNELRREALEYDRLQFLDYDEKREKPWVVQQ
LDSAEGPVVASTDYMKLYADQIRAWVPSDFHVLGTDGFGRSDTREALRRFFEVDRYYVTIQALRALANRGEIDVKVVNDA
MKKYGIDPAKPSPLVS
>Mature_895_residues
SLEAREDLDPIETTEWLDSLASVIEHEGEERARYIMSRLADRLRRDGSSPPFSGTTPHRNTIPMHREAKMPGDMFIERKI
RSAIRWNAMVQVLRANKKHKGLGGHIASYQSSATLYEVGFNHFFRADNGDHKGDLLYIQGHVTPGIYARSFLEGRLTEEQ
MDNFRQEVDGDALPSYPHPYLMPDYWQFPTVSMGLGPIQAIYQAHVMKYLHSRELEDMKDRKVWAFLGDGECDEPETLGA
LHLASREKLDNLIFVINCNLQRLDGPVRGNSRIIDELEGVFRGAGWNVIKVVWGGQWDPLFEQDANGMLQKRMDEAVDGE
YQNYKAQGGAYTREHFFGKYEETAAMVKDYTDEQIFRLNRGGHDPQKVYAAYHEAVNNAGNRPTVILAHTVKGYGMGGGS
GEADMEAHQIKSMDTDALKAFRDRFGIPISDKQIESGDIPYYKPDDDSPEMKYLHLQREKLGGFLPARKNDFEALEIPGL
DDKMFASQLKGSGDREVSSTMSFVRVLNGLVKNKQLGSRVVPIIPDEARTFGMEGMFRQLGIYAAEGQKYEPMDAGQIMY
YREDQKGQILEEGITEAGSMSAWIAAATAYANHHLPLIPFYVYYSMFGYQRVGDLVWAAGDLQARGFMIGGTAGRTTING
EGLQHQDGHSHILMSTVPTCRAYDPCYGHEVAVILQDGLKRMFQDKENCFYYLTVMNENYPHPEMPEGSEEGIVRGMYRL
SEGKKDGRKKQPRVQLLGSGTILREVEAAAEMLAEEHGVVADVWSVTSFNELRREALEYDRLQFLDYDEKREKPWVVQQL
DSAEGPVVASTDYMKLYADQIRAWVPSDFHVLGTDGFGRSDTREALRRFFEVDRYYVTIQALRALANRGEIDVKVVNDAM
KKYGIDPAKPSPLVS

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=902, Percent_Identity=58.3148558758315, Blast_Score=1077, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 101407; Mature: 101275

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEAREDLDPIETTEWLDSLASVIEHEGEERARYIMSRLADRLRRDGSSPPFSGTTPHR
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NTIPMHREAKMPGDMFIERKIRSAIRWNAMVQVLRANKKHKGLGGHIASYQSSATLYEVG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEEC
FNHFFRADNGDHKGDLLYIQGHVTPGIYARSFLEGRLTEEQMDNFRQEVDGDALPSYPHP
HHHHEECCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCC
YLMPDYWQFPTVSMGLGPIQAIYQAHVMKYLHSRELEDMKDRKVWAFLGDGECDEPETLG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHH
ALHLASREKLDNLIFVINCNLQRLDGPVRGNSRIIDELEGVFRGAGWNVIKVVWGGQWDP
HHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCC
LFEQDANGMLQKRMDEAVDGEYQNYKAQGGAYTREHFFGKYEETAAMVKDYTDEQIFRLN
HHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHCCCHHHHHHHHHHCCHHHHHHHC
RGGHDPQKVYAAYHEAVNNAGNRPTVILAHTVKGYGMGGGSGEADMEAHQIKSMDTDALK
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCHHHHH
AFRDRFGIPISDKQIESGDIPYYKPDDDSPEMKYLHLQREKLGGFLPARKNDFEALEIPG
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCC
LDDKMFASQLKGSGDREVSSTMSFVRVLNGLVKNKQLGSRVVPIIPDEARTFGMEGMFRQ
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCHHHHHHH
LGIYAAEGQKYEPMDAGQIMYYREDQKGQILEEGITEAGSMSAWIAAATAYANHHLPLIP
HCEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHH
FYVYYSMFGYQRVGDLVWAAGDLQARGFMIGGTAGRTTINGEGLQHQDGHSHILMSTVPT
HHHHHHHHHHHHHHHHHEECCCCCCCCEEEECCCCCEEECCCCCCCCCCCCEEEEECCCC
CRAYDPCYGHEVAVILQDGLKRMFQDKENCFYYLTVMNENYPHPEMPEGSEEGIVRGMYR
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
LSEGKKDGRKKQPRVQLLGSGTILREVEAAAEMLAEEHGVVADVWSVTSFNELRREALEY
HHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
DRLQFLDYDEKREKPWVVQQLDSAEGPVVASTDYMKLYADQIRAWVPSDFHVLGTDGFGR
HHHHHCCCHHHCCCCHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCC
SDTREALRRFFEVDRYYVTIQALRALANRGEIDVKVVNDAMKKYGIDPAKPSPLVS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SLEAREDLDPIETTEWLDSLASVIEHEGEERARYIMSRLADRLRRDGSSPPFSGTTPHR
CCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NTIPMHREAKMPGDMFIERKIRSAIRWNAMVQVLRANKKHKGLGGHIASYQSSATLYEVG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEEC
FNHFFRADNGDHKGDLLYIQGHVTPGIYARSFLEGRLTEEQMDNFRQEVDGDALPSYPHP
HHHHEECCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCC
YLMPDYWQFPTVSMGLGPIQAIYQAHVMKYLHSRELEDMKDRKVWAFLGDGECDEPETLG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHH
ALHLASREKLDNLIFVINCNLQRLDGPVRGNSRIIDELEGVFRGAGWNVIKVVWGGQWDP
HHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCC
LFEQDANGMLQKRMDEAVDGEYQNYKAQGGAYTREHFFGKYEETAAMVKDYTDEQIFRLN
HHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHCCCHHHHHHHHHHCCHHHHHHHC
RGGHDPQKVYAAYHEAVNNAGNRPTVILAHTVKGYGMGGGSGEADMEAHQIKSMDTDALK
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCHHHHH
AFRDRFGIPISDKQIESGDIPYYKPDDDSPEMKYLHLQREKLGGFLPARKNDFEALEIPG
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCC
LDDKMFASQLKGSGDREVSSTMSFVRVLNGLVKNKQLGSRVVPIIPDEARTFGMEGMFRQ
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCHHHHHHH
LGIYAAEGQKYEPMDAGQIMYYREDQKGQILEEGITEAGSMSAWIAAATAYANHHLPLIP
HCEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHH
FYVYYSMFGYQRVGDLVWAAGDLQARGFMIGGTAGRTTINGEGLQHQDGHSHILMSTVPT
HHHHHHHHHHHHHHHHHEECCCCCCCCEEEECCCCCEEECCCCCCCCCCCCEEEEECCCC
CRAYDPCYGHEVAVILQDGLKRMFQDKENCFYYLTVMNENYPHPEMPEGSEEGIVRGMYR
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
LSEGKKDGRKKQPRVQLLGSGTILREVEAAAEMLAEEHGVVADVWSVTSFNELRREALEY
HHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
DRLQFLDYDEKREKPWVVQQLDSAEGPVVASTDYMKLYADQIRAWVPSDFHVLGTDGFGR
HHHHHCCCHHHCCCCHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCC
SDTREALRRFFEVDRYYVTIQALRALANRGEIDVKVVNDAMKKYGIDPAKPSPLVS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9171401; 10984043 [H]