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The map label for this gene is pcaQ [H]

Identifier: 92112464

GI number: 92112464

Start: 368389

End: 369642

Strand: Direct

Name: pcaQ [H]

Synonym: Csal_0331

Alternate gene names: 92112464

Gene position: 368389-369642 (Clockwise)

Preceding gene: 92112452

Following gene: 92112465

Centisome position: 9.97

GC content: 65.63

Gene sequence:

>1254_bases
ATGACCGAACTGCATCGCGAGGCATTCGATTACGCACCCAACATGCGGCGCTTGCGTGCGGTCATCGCCGTGGCCGAGGC
GGGCAGCGTGATGCGGGCGGCCGAGGCATTGCATCTGTCGCAACCCGCCGTGACACGGGCGGTGCGTGACCTGGAAAAGG
AGCTCGGCCTGGCGCTGTTCGAGCGCCATCGCAGCGGCATGTTATGCACCACGGCGGGGAAGATAGTCCTGCATCGCTTC
CGGCGTGCCTTGCAGCAATTGATCGAGGCCGAGACCGCGCTGGCACGTCTGCACCCCGAGGGCAATTTCGAGCGCCTCCC
GCAACGCTTGTCGCATCGTCAGTTGACGGTGCTGGTGGCCGTCGCCGACCTGCATAACGAGCCCCTGGCGGCCAAACGCC
TGGGGCTGACCCAGCCGGCGGTCAGTGGCAATCTGCGCGACCTGGAACGCCTGCTGGGCATCGCGCTGTTCCTGCGCACG
CAACGCGGCATGCTGGCCACCGATGGCGGTGCGGTGCTGATTCGTCATGCCAAGATGGCCTTGCGCGAGCTGTCCCTAGT
CAGCGATGACCTCTCCGCCTGGCAGGGCGAGGTGCGGGGTCGCGTGGTGATCGGTACCTTGCCGCTTTCCAGCTCGCTAC
TGGTGCCACATGCCGTGGATGCCTTGTTGCGTGAATTGCCGGGCCTGAACGTGACGATCATCGAGGGCACCTACGACGCC
CTGTTCGAGTCGCTGCGTCATGGCGAGATCGATATCCTCATCGGTGCGCTGCGTCAGGCGGGTACCAGCGAGGACACGCA
TCAGCAACGTCTCTTCCATGACCGCCTCGCCGTCGCGGCACGCCAAGGGCATCCCCTGATGAAGCACGCCGCGCTGCAAT
TGAGCGATCTGCTCGATGCGCAATGGATCGCCCCCCGGCAGGGCACGCCGGCGCGCGTGAGTTTCGAGCAGGAGTTTCGC
AGTGCCGGCCTGCAGCCGCCTTCGGTCGTGGTGGAGTCCGGCAATCTCAGCACGATTCGCACCCTGCTGCTCGACAGCGA
CCGCGTGACGCTGGTCTCGCCCCATCAGGTGTTCTTCGAAGTCCAGAGCGGCCAGCTGGCGCTGCTTCCCATCAAGCTGA
CGGGCACGCTCCGTCCGATCGGCATCACCACACGTGCCGACGACTCCCCGACCCAGGCCTTGAAAGTCCTCAAGGACATC
TTGCTGACGCTTGGGGAGCGCATGGCCGACCCTTCCTCGGCTACCCGGGCGTGA

Upstream 100 bases:

>100_bases
ATCCCCGCCACGGCGCGGTTGGCCATGCTCCCTTTATGGCATATCGCGCGGCGCCGCCATGCGGCATGCTGGACGCAGAT
TCATGTCGAAGAGGTCAGCC

Downstream 100 bases:

>100_bases
CCGGGATAGCAAAAACGTATACCCAAGCACGCGATTTGAATTTGTTGCCGTGACTGAGGGCCGGGTACGGTGCTTTCAGG
CTCCGTTTCTTTATGCATTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Pca operon transcriptional activator [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTELHREAFDYAPNMRRLRAVIAVAEAGSVMRAAEALHLSQPAVTRAVRDLEKELGLALFERHRSGMLCTTAGKIVLHRF
RRALQQLIEAETALARLHPEGNFERLPQRLSHRQLTVLVAVADLHNEPLAAKRLGLTQPAVSGNLRDLERLLGIALFLRT
QRGMLATDGGAVLIRHAKMALRELSLVSDDLSAWQGEVRGRVVIGTLPLSSSLLVPHAVDALLRELPGLNVTIIEGTYDA
LFESLRHGEIDILIGALRQAGTSEDTHQQRLFHDRLAVAARQGHPLMKHAALQLSDLLDAQWIAPRQGTPARVSFEQEFR
SAGLQPPSVVVESGNLSTIRTLLLDSDRVTLVSPHQVFFEVQSGQLALLPIKLTGTLRPIGITTRADDSPTQALKVLKDI
LLTLGERMADPSSATRA

Sequences:

>Translated_417_residues
MTELHREAFDYAPNMRRLRAVIAVAEAGSVMRAAEALHLSQPAVTRAVRDLEKELGLALFERHRSGMLCTTAGKIVLHRF
RRALQQLIEAETALARLHPEGNFERLPQRLSHRQLTVLVAVADLHNEPLAAKRLGLTQPAVSGNLRDLERLLGIALFLRT
QRGMLATDGGAVLIRHAKMALRELSLVSDDLSAWQGEVRGRVVIGTLPLSSSLLVPHAVDALLRELPGLNVTIIEGTYDA
LFESLRHGEIDILIGALRQAGTSEDTHQQRLFHDRLAVAARQGHPLMKHAALQLSDLLDAQWIAPRQGTPARVSFEQEFR
SAGLQPPSVVVESGNLSTIRTLLLDSDRVTLVSPHQVFFEVQSGQLALLPIKLTGTLRPIGITTRADDSPTQALKVLKDI
LLTLGERMADPSSATRA
>Mature_416_residues
TELHREAFDYAPNMRRLRAVIAVAEAGSVMRAAEALHLSQPAVTRAVRDLEKELGLALFERHRSGMLCTTAGKIVLHRFR
RALQQLIEAETALARLHPEGNFERLPQRLSHRQLTVLVAVADLHNEPLAAKRLGLTQPAVSGNLRDLERLLGIALFLRTQ
RGMLATDGGAVLIRHAKMALRELSLVSDDLSAWQGEVRGRVVIGTLPLSSSLLVPHAVDALLRELPGLNVTIIEGTYDAL
FESLRHGEIDILIGALRQAGTSEDTHQQRLFHDRLAVAARQGHPLMKHAALQLSDLLDAQWIAPRQGTPARVSFEQEFRS
AGLQPPSVVVESGNLSTIRTLLLDSDRVTLVSPHQVFFEVQSGQLALLPIKLTGTLRPIGITTRADDSPTQALKVLKDIL
LTLGERMADPSSATRA

Specific function: Activates transcription of the pcaDCHGB operon for the catabolism of the phenolic compound protocatechuate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=261, Percent_Identity=29.1187739463602, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87081904, Length=294, Percent_Identity=27.5510204081633, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789506, Length=245, Percent_Identity=24.4897959183673, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790399, Length=274, Percent_Identity=27.7372262773723, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI157672245, Length=240, Percent_Identity=27.0833333333333, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693105, Length=208, Percent_Identity=25, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR012787
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 45734; Mature: 45602

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELHREAFDYAPNMRRLRAVIAVAEAGSVMRAAEALHLSQPAVTRAVRDLEKELGLALF
CCCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ERHRSGMLCTTAGKIVLHRFRRALQQLIEAETALARLHPEGNFERLPQRLSHRQLTVLVA
HHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEE
VADLHNEPLAAKRLGLTQPAVSGNLRDLERLLGIALFLRTQRGMLATDGGAVLIRHAKMA
EECCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEHHHHHHH
LRELSLVSDDLSAWQGEVRGRVVIGTLPLSSSLLVPHAVDALLRELPGLNVTIIEGTYDA
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHH
LFESLRHGEIDILIGALRQAGTSEDTHQQRLFHDRLAVAARQGHPLMKHAALQLSDLLDA
HHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QWIAPRQGTPARVSFEQEFRSAGLQPPSVVVESGNLSTIRTLLLDSDRVTLVSPHQVFFE
HCCCCCCCCCCEEEHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCEEEECCCEEEEE
VQSGQLALLPIKLTGTLRPIGITTRADDSPTQALKVLKDILLTLGERMADPSSATRA
ECCCCEEEEEEEEECCEEECEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TELHREAFDYAPNMRRLRAVIAVAEAGSVMRAAEALHLSQPAVTRAVRDLEKELGLALF
CCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ERHRSGMLCTTAGKIVLHRFRRALQQLIEAETALARLHPEGNFERLPQRLSHRQLTVLVA
HHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEE
VADLHNEPLAAKRLGLTQPAVSGNLRDLERLLGIALFLRTQRGMLATDGGAVLIRHAKMA
EECCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEHHHHHHH
LRELSLVSDDLSAWQGEVRGRVVIGTLPLSSSLLVPHAVDALLRELPGLNVTIIEGTYDA
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHH
LFESLRHGEIDILIGALRQAGTSEDTHQQRLFHDRLAVAARQGHPLMKHAALQLSDLLDA
HHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QWIAPRQGTPARVSFEQEFRSAGLQPPSVVVESGNLSTIRTLLLDSDRVTLVSPHQVFFE
HCCCCCCCCCCEEEHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCEEEECCCEEEEE
VQSGQLALLPIKLTGTLRPIGITTRADDSPTQALKVLKDILLTLGERMADPSSATRA
ECCCCEEEEEEEEECCEEECEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]