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The map label for this gene is eamA [H]

Identifier: 91785035

GI number: 91785035

Start: 4056936

End: 4057838

Strand: Reverse

Name: eamA [H]

Synonym: Bxe_A0745

Alternate gene names: 91785035

Gene position: 4057838-4056936 (Counterclockwise)

Preceding gene: 91785038

Following gene: 91785032

Centisome position: 82.88

GC content: 65.89

Gene sequence:

>903_bases
ATGTCGCCCAGGGATTTGCTGCTCGCGCTGGTCGTCGTCGTGGCATGGGGCATCAACTTCGTCGTGATCAAGGTGGGTCT
GCATGGCGTGCCGCCGATGCTGCTCGGCGCGCTGCGCTTCACGCTCGCCGCGGTGCCGGCGGTGTTTTTCATCAAACGGC
CCAACCTGCCGTGGCGCTGGCTGCTCGCCTACGGCGCGACGATCTCGTTCGGGCAGTTCGCTTTTCTGTTCTCGGCCATG
TATGTCGGCATGCCGGCCGGACTCGCGTCGCTGGTGTTGCAGGCGCAGGCGTTCTTTACGCTGATCTTCGCGGCTATCTT
CCTGCATGAGCGGTTCCGCTTGCCGAATGTCGCGGGATTGGCGATCGCGGCGGCCGGGCTTGCCGTGATCGGCATGCAAG
GGGGGCGTGCCATGACGCTGGCCGGTTTCGTCCTCACGCTGTGCGCCGCGTGTTCGTGGGCGCTCGGCAACATCGTCACG
AAGAAGGTCGGCAAGGTCGATCTCGTCGGACTCGTGGTGTGGGGCAGCCTGATTCCGCCGCTGCCGTTTTTTGCGCTGTC
GTACGCGTTCGAGGGCCCGCAGCGGATCGCCGCGGCGCTCGCCGGCATCAGCGCGATGTCGATCTTCGCGATCGTGTATC
TCGCGTTCATTGCCACGCTGCTCGGCTACGGCTTGTGGAGCCGGCTGCTGTCGCGCTACCCGGCAAGCCAGGTCGCGCCG
TTTTCGCTGCTGGTGCCGATTGTCGGGCTCGCGTCGGCGTCGCTGTTTCTCGACGAGCAACTGTCCTCGGCGCAGATCGC
CGGTGCGTTGCTGGTGATGGCGGGGTTGGCCGTGAACGTGTTCGGCGGCTGGGTGGTGCAGCGGTTTTCGCCGGCGCGTC
GGGCAACTGACGCGTCTGATTGA

Upstream 100 bases:

>100_bases
CGGCGTTCCGGGAATCCGTAATGCGGTCCATCGGGCGGTCCATCGCCCGCTTCTGCCGGCTCCGCTAAACTGCCGGATCG
AACAATCAATTGGAGAGCGC

Downstream 100 bases:

>100_bases
GCACGAAAGACGCGCGCGAAAACGCGCACCACGACGACGAAAATACGGCCGCATCGAGCGGCCGTATTTCATTGTGTTGC
TGCAAGCGAAGTCATCACGT

Product: DMT superfamily drug/metabolite efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSPRDLLLALVVVVAWGINFVVIKVGLHGVPPMLLGALRFTLAAVPAVFFIKRPNLPWRWLLAYGATISFGQFAFLFSAM
YVGMPAGLASLVLQAQAFFTLIFAAIFLHERFRLPNVAGLAIAAAGLAVIGMQGGRAMTLAGFVLTLCAACSWALGNIVT
KKVGKVDLVGLVVWGSLIPPLPFFALSYAFEGPQRIAAALAGISAMSIFAIVYLAFIATLLGYGLWSRLLSRYPASQVAP
FSLLVPIVGLASASLFLDEQLSSAQIAGALLVMAGLAVNVFGGWVVQRFSPARRATDASD

Sequences:

>Translated_300_residues
MSPRDLLLALVVVVAWGINFVVIKVGLHGVPPMLLGALRFTLAAVPAVFFIKRPNLPWRWLLAYGATISFGQFAFLFSAM
YVGMPAGLASLVLQAQAFFTLIFAAIFLHERFRLPNVAGLAIAAAGLAVIGMQGGRAMTLAGFVLTLCAACSWALGNIVT
KKVGKVDLVGLVVWGSLIPPLPFFALSYAFEGPQRIAAALAGISAMSIFAIVYLAFIATLLGYGLWSRLLSRYPASQVAP
FSLLVPIVGLASASLFLDEQLSSAQIAGALLVMAGLAVNVFGGWVVQRFSPARRATDASD
>Mature_299_residues
SPRDLLLALVVVVAWGINFVVIKVGLHGVPPMLLGALRFTLAAVPAVFFIKRPNLPWRWLLAYGATISFGQFAFLFSAMY
VGMPAGLASLVLQAQAFFTLIFAAIFLHERFRLPNVAGLAIAAAGLAVIGMQGGRAMTLAGFVLTLCAACSWALGNIVTK
KVGKVDLVGLVVWGSLIPPLPFFALSYAFEGPQRIAAALAGISAMSIFAIVYLAFIATLLGYGLWSRLLSRYPASQVAPF
SLLVPIVGLASASLFLDEQLSSAQIAGALLVMAGLAVNVFGGWVVQRFSPARRATDASD

Specific function: May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O- acetyl-L-serine (OAS)), and for other amino acids and their metabolites [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI87081929, Length=288, Percent_Identity=52.7777777777778, Blast_Score=270, Evalue=8e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 31717; Mature: 31586

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRDLLLALVVVVAWGINFVVIKVGLHGVPPMLLGALRFTLAAVPAVFFIKRPNLPWRW
CCHHHHHHHHHHHHHHCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHH
LLAYGATISFGQFAFLFSAMYVGMPAGLASLVLQAQAFFTLIFAAIFLHERFRLPNVAGL
HHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AIAAAGLAVIGMQGGRAMTLAGFVLTLCAACSWALGNIVTKKVGKVDLVGLVVWGSLIPP
HHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
LPFFALSYAFEGPQRIAAALAGISAMSIFAIVYLAFIATLLGYGLWSRLLSRYPASQVAP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
FSLLVPIVGLASASLFLDEQLSSAQIAGALLVMAGLAVNVFGGWVVQRFSPARRATDASD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
>Mature Secondary Structure 
SPRDLLLALVVVVAWGINFVVIKVGLHGVPPMLLGALRFTLAAVPAVFFIKRPNLPWRW
CHHHHHHHHHHHHHHCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHH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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 10844694 [H]