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The map label for this gene is purN [H]

Identifier: 91784971

GI number: 91784971

Start: 3982646

End: 3983257

Strand: Reverse

Name: purN [H]

Synonym: Bxe_A0809

Alternate gene names: 91784971

Gene position: 3983257-3982646 (Counterclockwise)

Preceding gene: 91784979

Following gene: 91784970

Centisome position: 81.36

GC content: 66.34

Gene sequence:

>612_bases
ATGGAAGCCATTGTTCGAGCCCGCTCGGACGAAGCCTGGCCCGCGCAAGTCGCGGCCGTGATTGCCAACCGTCCTGATGC
CGCGGGCCTTGCGTTCGCGGCGTCGCACGGCATTGCCACGGCGGTGGTCGACCACCGCCAGTTTTCCGGCCGCGACAGCT
TCGACGCCGCGCTCGCTCAAAAAATCGACAGTTTCGCGCCCGATCTGGTGGTGCTCGCCGGCTTCATGCGGGTGCTCACG
GCCGGTTTCGTCGATCACTACGCCGGCCGCATGCTGAATGTGCATCCGTCGCTGCTGCCGAGCTTTCCGGGCCTGAAAAC
CCATCAGCAGGCGCTCGACGCGGGCGTGCGGCTGCACGGCGCGTCCGTGCATTTTGTCACCTCGCAGCTGGATCACGGGC
CGATCGTCGTACAGTCGGCGGTTCCCGTTGAAACGGGCGACACTCCCGCCACGCTCGCCGAACGCGTGCTGGCAACCGAA
CACATCATTTATCCACGCGCGGTGCGCTGGTTCGTCGAAGGGCGCCTTGCTCTCGAAGGCCTGCGTGTCACGCTTACGCC
GCCGGAGCCGCAATGGCTCTTTGCCGGTCACACCGCCGGAGAGGGCGCATGA

Upstream 100 bases:

>100_bases
AGCGCAATGGACGGCGGAGCGTCGCGGTTTCAGTGTCCCCGAATGATAAAATCCGCGGATGAAAAAACTCGTCATCCTGA
TTTCCGGACGGGGAAGCAAC

Downstream 100 bases:

>100_bases
GATTGCATGGTTTTCTGATTGGACAAACTGAGACTTTGTTGGCTGAAGTCCTAAAACTCAACGGCCCGGCCGACGCCACC
ACGAGCCGTTTCTTCCGCGC

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MEAIVRARSDEAWPAQVAAVIANRPDAAGLAFAASHGIATAVVDHRQFSGRDSFDAALAQKIDSFAPDLVVLAGFMRVLT
AGFVDHYAGRMLNVHPSLLPSFPGLKTHQQALDAGVRLHGASVHFVTSQLDHGPIVVQSAVPVETGDTPATLAERVLATE
HIIYPRAVRWFVEGRLALEGLRVTLTPPEPQWLFAGHTAGEGA

Sequences:

>Translated_203_residues
MEAIVRARSDEAWPAQVAAVIANRPDAAGLAFAASHGIATAVVDHRQFSGRDSFDAALAQKIDSFAPDLVVLAGFMRVLT
AGFVDHYAGRMLNVHPSLLPSFPGLKTHQQALDAGVRLHGASVHFVTSQLDHGPIVVQSAVPVETGDTPATLAERVLATE
HIIYPRAVRWFVEGRLALEGLRVTLTPPEPQWLFAGHTAGEGA
>Mature_203_residues
MEAIVRARSDEAWPAQVAAVIANRPDAAGLAFAASHGIATAVVDHRQFSGRDSFDAALAQKIDSFAPDLVVLAGFMRVLT
AGFVDHYAGRMLNVHPSLLPSFPGLKTHQQALDAGVRLHGASVHFVTSQLDHGPIVVQSAVPVETGDTPATLAERVLATE
HIIYPRAVRWFVEGRLALEGLRVTLTPPEPQWLFAGHTAGEGA

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=178, Percent_Identity=44.3820224719101, Blast_Score=164, Evalue=7e-41,
Organism=Homo sapiens, GI209869995, Length=178, Percent_Identity=44.3820224719101, Blast_Score=164, Evalue=7e-41,
Organism=Homo sapiens, GI209869993, Length=178, Percent_Identity=44.3820224719101, Blast_Score=164, Evalue=7e-41,
Organism=Escherichia coli, GI1788846, Length=178, Percent_Identity=49.438202247191, Blast_Score=183, Evalue=6e-48,
Organism=Escherichia coli, GI1787483, Length=170, Percent_Identity=32.9411764705882, Blast_Score=97, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17567511, Length=152, Percent_Identity=42.1052631578947, Blast_Score=129, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24582400, Length=176, Percent_Identity=42.0454545454545, Blast_Score=146, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 21636; Mature: 21636

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIVRARSDEAWPAQVAAVIANRPDAAGLAFAASHGIATAVVDHRQFSGRDSFDAALAQ
CCCHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCHHEEHHHHHHCCCCCHHHHHHHH
KIDSFAPDLVVLAGFMRVLTAGFVDHYAGRMLNVHPSLLPSFPGLKTHQQALDAGVRLHG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHCCCCCCCHHHHHHHHCCEEEEC
ASVHFVTSQLDHGPIVVQSAVPVETGDTPATLAERVLATEHIIYPRAVRWFVEGRLALEG
CEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
LRVTLTPPEPQWLFAGHTAGEGA
EEEEECCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MEAIVRARSDEAWPAQVAAVIANRPDAAGLAFAASHGIATAVVDHRQFSGRDSFDAALAQ
CCCHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCHHEEHHHHHHCCCCCHHHHHHHH
KIDSFAPDLVVLAGFMRVLTAGFVDHYAGRMLNVHPSLLPSFPGLKTHQQALDAGVRLHG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHCCCCCCCHHHHHHHHCCEEEEC
ASVHFVTSQLDHGPIVVQSAVPVETGDTPATLAERVLATEHIIYPRAVRWFVEGRLALEG
CEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
LRVTLTPPEPQWLFAGHTAGEGA
EEEEECCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301838; 9205837; 9278503; 10954745; 2204419; 1522592; 1631098; 9698564; 10606510 [H]