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The map label for this gene is clpA [H]

Identifier: 91784979

GI number: 91784979

Start: 3993836

End: 3996133

Strand: Reverse

Name: clpA [H]

Synonym: Bxe_A0801

Alternate gene names: 91784979

Gene position: 3996133-3993836 (Counterclockwise)

Preceding gene: 91784980

Following gene: 91784971

Centisome position: 81.62

GC content: 61.75

Gene sequence:

>2298_bases
ATGATTGCCCAGGAACTGGAAGTCAGCCTGCACATGGCGTTCATGGAAGCACGCCAGGCGCGGCACGAGTTCATAACGGT
CGAACATCTTTTGCTGGCACTGTTGGACAATCCGACAGCAGCGGAGGTGTTGCGTGCATGCGCGGCCAATATCGAGGATC
TGCGCCAGAACCTGCGCAACTTCATTCATGACAACACGCCGACCGTGCCTGGCACGGACGACGTCGACACGCAGCCCACG
CTGGGTTTCCAGCGTGTGATCCAGCGCGCGATCATGCATGTTCAGTCCACCTCGAATGGCAAGAAGGAAGTGACTGGCGC
CAACGTGCTGGTCGCGATCTTCGGCGAGAAGGACTCGCACGCGGTGTACTACCTGCAGCAGCAGGGCGTGACGCGTCTGG
ACGTGGTCAATTTCATCTCGCACGGCATCGCCAAGACGAGCAGCACCGACGCCGCGAAAGCGAGCGACGCGAATGCCGAG
TCCGACGAAGCCGCCGCGCAGAAAGAAACCCCGCTCGCGCAGTTCACCCAGAACCTGAACCAGATGGCGAAAGACGGCCG
CATCGATCCGCTGATCGGGCGCGAGTCGGAAGTCGAGCGTGTGGTGCAGGTGCTGTGCCGCCGCCGCAAGAACAATCCGC
TGCTGGTCGGTGAGGCGGGCGTCGGCAAGACCGCGATCGCCGAGGGTCTGGCGTGGCGCATTACGCGCGGCGAAGTGCCG
GACATTCTGGCGGATGCGCAGGTGTATTCGCTCGACATGGGCGCGCTGCTCGCCGGCACCAAGTATCGCGGCGACTTCGA
ACAGCGCCTGAAGACGGTCCTCAAGGAATTGAAGGAACGTCCGCACGCTATCCTGTTCATCGACGAAATTCATACGCTGA
TCGGCGCGGGCGCTGCGTCGGGCGGCACGCTGGACGCGTCGAACCTGCTCAAGCCGGCGTTGTCGTCGGGCACGCTGAAG
TGCATCGGCGCGACCACGTTCACGGAATATCGCGGCATCTTCGAAAAAGACGCAGCCTTGTCGCGGCGTTTCCAGAAGGT
CGACGTGACCGAGCCGACCGTCGAACAAACGGTGGCGATCCTGCGTGGCCTGAAGTCGCGGTTCGAAGAGCACCACGGCG
TGAAGTATTCGTCGGGCGCGCTGTCGGCGGCGGCTGAGTTGTCGGCACGCTTCATCACGGATCGTCATCTGCCGGACAAG
GCAATCGACGTGATCGACGAAGCGGGCGCGGCGCAACGCATCCTGCCGAAGTCGAAACAGAAGAAGACCATTGGCAAGAA
CGAGATCGAGGAAATCATCTCGAAGATCGCCCGCGTCCCGCCACAAAGCGTGTCGCAAGACGATCGCAGCAAGCTGCAAA
CGCTGGATCGCGATCTGAAGAGCGTGGTGTTCGGGCAAGACCCGGCCATCGACGCGCTGTCGGCCGCGATCAAGATGGCG
CGTGCGGGTCTCGGCAAGCTGGACAAGCCGATCGGCGCATTCCTGTTCTCCGGCCCCACGGGCGTCGGCAAGACGGAAGT
GGCAAAGCAGCTGGCGTTCACGCTGGGCATCGAGCTGATCCGCTTCGACATGTCGGAATACATGGAGCGTCATGCGGTCA
GCCGGTTGATCGGCGCGCCGCCGGGCTATGTCGGTTTCGACCAGGGCGGTCTGCTGACCGAGGCTGTCACGAAGAAGCCG
CATTGCGTGCTGCTGCTCGACGAAATCGAGAAGGCGCATCCGGACATCTACAACGTGCTGCTGCAGGTGATGGACCACGG
CACGCTGACGGACAACAACGGCCGCAAGGCGGATTTCCGCAACGTCATCATCATCATGACGACGAACGCGGGCGCCGAGG
CAATGGGCAAGTCGGTGATCGGCTTCACGAATCGTCGGGAAACCGGCGACGAGATGGTCGACATCAAGCGCATGTTCACG
CCTGAGTTCCGTAACCGTCTGGATGCGGTGATCAGCTTCCGCTCGCTCGACGAAGAAATCATCATGCGCGTGGTCGACAA
GTTCCTGATGCAGCTGGAAGATCAGTTGCACGAGAAGAAGGTCGATGCGCTCTTCACCGACGCGTTGCGCAAGCATCTCG
CCAAGCACGGTTTCGATCCGCTCATGGGCGCGCGGCCGATGCAGCGTCTGATTCAGGACACGATCCGTCGTGCACTGGCC
GACGAACTACTGTTCGGCAAGCTGATGAACGGCGGTCGCGTGACGGTCGACGTGGATGCGGAAGACAAGGTGCAACTGAC
GTTCGACGAGCATCCGGCGCCGCGCAATCCGAATCCGGAAGCAGTGGAAGTCGAATAA

Upstream 100 bases:

>100_bases
GTGGGGTCTATACGCGGGACATCGCGTCGACCAAAGTCGAGCAAGTCGTTACCCACGCACGGCAGGCCGGGCATCCGCTG
CAGTGTGTGATGGAGGAAGC

Downstream 100 bases:

>100_bases
GCGCAAACGGTAGCACTGAAAAAACGGCGTGGACTCAGGTCCACGCCGTTTTTCTTTAGGGCTGGTGTTATTGATCGAAC
CTGATCGGATCGTTCATGTA

Product: putative ATP-dependent Clp protease ATP- binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 765; Mature: 765

Protein sequence:

>765_residues
MIAQELEVSLHMAFMEARQARHEFITVEHLLLALLDNPTAAEVLRACAANIEDLRQNLRNFIHDNTPTVPGTDDVDTQPT
LGFQRVIQRAIMHVQSTSNGKKEVTGANVLVAIFGEKDSHAVYYLQQQGVTRLDVVNFISHGIAKTSSTDAAKASDANAE
SDEAAAQKETPLAQFTQNLNQMAKDGRIDPLIGRESEVERVVQVLCRRRKNNPLLVGEAGVGKTAIAEGLAWRITRGEVP
DILADAQVYSLDMGALLAGTKYRGDFEQRLKTVLKELKERPHAILFIDEIHTLIGAGAASGGTLDASNLLKPALSSGTLK
CIGATTFTEYRGIFEKDAALSRRFQKVDVTEPTVEQTVAILRGLKSRFEEHHGVKYSSGALSAAAELSARFITDRHLPDK
AIDVIDEAGAAQRILPKSKQKKTIGKNEIEEIISKIARVPPQSVSQDDRSKLQTLDRDLKSVVFGQDPAIDALSAAIKMA
RAGLGKLDKPIGAFLFSGPTGVGKTEVAKQLAFTLGIELIRFDMSEYMERHAVSRLIGAPPGYVGFDQGGLLTEAVTKKP
HCVLLLDEIEKAHPDIYNVLLQVMDHGTLTDNNGRKADFRNVIIIMTTNAGAEAMGKSVIGFTNRRETGDEMVDIKRMFT
PEFRNRLDAVISFRSLDEEIIMRVVDKFLMQLEDQLHEKKVDALFTDALRKHLAKHGFDPLMGARPMQRLIQDTIRRALA
DELLFGKLMNGGRVTVDVDAEDKVQLTFDEHPAPRNPNPEAVEVE

Sequences:

>Translated_765_residues
MIAQELEVSLHMAFMEARQARHEFITVEHLLLALLDNPTAAEVLRACAANIEDLRQNLRNFIHDNTPTVPGTDDVDTQPT
LGFQRVIQRAIMHVQSTSNGKKEVTGANVLVAIFGEKDSHAVYYLQQQGVTRLDVVNFISHGIAKTSSTDAAKASDANAE
SDEAAAQKETPLAQFTQNLNQMAKDGRIDPLIGRESEVERVVQVLCRRRKNNPLLVGEAGVGKTAIAEGLAWRITRGEVP
DILADAQVYSLDMGALLAGTKYRGDFEQRLKTVLKELKERPHAILFIDEIHTLIGAGAASGGTLDASNLLKPALSSGTLK
CIGATTFTEYRGIFEKDAALSRRFQKVDVTEPTVEQTVAILRGLKSRFEEHHGVKYSSGALSAAAELSARFITDRHLPDK
AIDVIDEAGAAQRILPKSKQKKTIGKNEIEEIISKIARVPPQSVSQDDRSKLQTLDRDLKSVVFGQDPAIDALSAAIKMA
RAGLGKLDKPIGAFLFSGPTGVGKTEVAKQLAFTLGIELIRFDMSEYMERHAVSRLIGAPPGYVGFDQGGLLTEAVTKKP
HCVLLLDEIEKAHPDIYNVLLQVMDHGTLTDNNGRKADFRNVIIIMTTNAGAEAMGKSVIGFTNRRETGDEMVDIKRMFT
PEFRNRLDAVISFRSLDEEIIMRVVDKFLMQLEDQLHEKKVDALFTDALRKHLAKHGFDPLMGARPMQRLIQDTIRRALA
DELLFGKLMNGGRVTVDVDAEDKVQLTFDEHPAPRNPNPEAVEVE
>Mature_765_residues
MIAQELEVSLHMAFMEARQARHEFITVEHLLLALLDNPTAAEVLRACAANIEDLRQNLRNFIHDNTPTVPGTDDVDTQPT
LGFQRVIQRAIMHVQSTSNGKKEVTGANVLVAIFGEKDSHAVYYLQQQGVTRLDVVNFISHGIAKTSSTDAAKASDANAE
SDEAAAQKETPLAQFTQNLNQMAKDGRIDPLIGRESEVERVVQVLCRRRKNNPLLVGEAGVGKTAIAEGLAWRITRGEVP
DILADAQVYSLDMGALLAGTKYRGDFEQRLKTVLKELKERPHAILFIDEIHTLIGAGAASGGTLDASNLLKPALSSGTLK
CIGATTFTEYRGIFEKDAALSRRFQKVDVTEPTVEQTVAILRGLKSRFEEHHGVKYSSGALSAAAELSARFITDRHLPDK
AIDVIDEAGAAQRILPKSKQKKTIGKNEIEEIISKIARVPPQSVSQDDRSKLQTLDRDLKSVVFGQDPAIDALSAAIKMA
RAGLGKLDKPIGAFLFSGPTGVGKTEVAKQLAFTLGIELIRFDMSEYMERHAVSRLIGAPPGYVGFDQGGLLTEAVTKKP
HCVLLLDEIEKAHPDIYNVLLQVMDHGTLTDNNGRKADFRNVIIIMTTNAGAEAMGKSVIGFTNRRETGDEMVDIKRMFT
PEFRNRLDAVISFRSLDEEIIMRVVDKFLMQLEDQLHEKKVDALFTDALRKHLAKHGFDPLMGARPMQRLIQDTIRRALA
DELLFGKLMNGGRVTVDVDAEDKVQLTFDEHPAPRNPNPEAVEVE

Specific function: ATP-dependent specificity component of the ClpP protease. It directs the protease to specific substrates. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=333, Percent_Identity=29.4294294294294, Blast_Score=155, Evalue=1e-37,
Organism=Escherichia coli, GI1787109, Length=750, Percent_Identity=61.8666666666667, Blast_Score=961, Evalue=0.0,
Organism=Escherichia coli, GI1788943, Length=403, Percent_Identity=44.9131513647643, Blast_Score=306, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6320464, Length=281, Percent_Identity=52.3131672597865, Blast_Score=287, Evalue=5e-78,
Organism=Saccharomyces cerevisiae, GI6323002, Length=304, Percent_Identity=46.7105263157895, Blast_Score=264, Evalue=4e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR013461
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 84233; Mature: 84233

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAQELEVSLHMAFMEARQARHEFITVEHLLLALLDNPTAAEVLRACAANIEDLRQNLRN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
FIHDNTPTVPGTDDVDTQPTLGFQRVIQRAIMHVQSTSNGKKEVTGANVLVAIFGEKDSH
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCC
AVYYLQQQGVTRLDVVNFISHGIAKTSSTDAAKASDANAESDEAAAQKETPLAQFTQNLN
EEEEEHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHH
QMAKDGRIDPLIGRESEVERVVQVLCRRRKNNPLLVGEAGVGKTAIAEGLAWRITRGEVP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCHHEEEECCCCC
DILADAQVYSLDMGALLAGTKYRGDFEQRLKTVLKELKERPHAILFIDEIHTLIGAGAAS
HHHHCCHHEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCC
GGTLDASNLLKPALSSGTLKCIGATTFTEYRGIFEKDAALSRRFQKVDVTEPTVEQTVAI
CCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LRGLKSRFEEHHGVKYSSGALSAAAELSARFITDRHLPDKAIDVIDEAGAAQRILPKSKQ
HHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCCHH
KKTIGKNEIEEIISKIARVPPQSVSQDDRSKLQTLDRDLKSVVFGQDPAIDALSAAIKMA
HHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RAGLGKLDKPIGAFLFSGPTGVGKTEVAKQLAFTLGIELIRFDMSEYMERHAVSRLIGAP
HHCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGYVGFDQGGLLTEAVTKKPHCVLLLDEIEKAHPDIYNVLLQVMDHGTLTDNNGRKADFR
CCCCCCCCCCCHHHHHCCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC
NVIIIMTTNAGAEAMGKSVIGFTNRRETGDEMVDIKRMFTPEFRNRLDAVISFRSLDEEI
CEEEEEECCCCHHHHCCHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHH
IMRVVDKFLMQLEDQLHEKKVDALFTDALRKHLAKHGFDPLMGARPMQRLIQDTIRRALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
DELLFGKLMNGGRVTVDVDAEDKVQLTFDEHPAPRNPNPEAVEVE
HHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCEECC
>Mature Secondary Structure
MIAQELEVSLHMAFMEARQARHEFITVEHLLLALLDNPTAAEVLRACAANIEDLRQNLRN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
FIHDNTPTVPGTDDVDTQPTLGFQRVIQRAIMHVQSTSNGKKEVTGANVLVAIFGEKDSH
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCC
AVYYLQQQGVTRLDVVNFISHGIAKTSSTDAAKASDANAESDEAAAQKETPLAQFTQNLN
EEEEEHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHH
QMAKDGRIDPLIGRESEVERVVQVLCRRRKNNPLLVGEAGVGKTAIAEGLAWRITRGEVP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCHHEEEECCCCC
DILADAQVYSLDMGALLAGTKYRGDFEQRLKTVLKELKERPHAILFIDEIHTLIGAGAAS
HHHHCCHHEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCC
GGTLDASNLLKPALSSGTLKCIGATTFTEYRGIFEKDAALSRRFQKVDVTEPTVEQTVAI
CCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LRGLKSRFEEHHGVKYSSGALSAAAELSARFITDRHLPDKAIDVIDEAGAAQRILPKSKQ
HHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCCHH
KKTIGKNEIEEIISKIARVPPQSVSQDDRSKLQTLDRDLKSVVFGQDPAIDALSAAIKMA
HHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RAGLGKLDKPIGAFLFSGPTGVGKTEVAKQLAFTLGIELIRFDMSEYMERHAVSRLIGAP
HHCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGYVGFDQGGLLTEAVTKKPHCVLLLDEIEKAHPDIYNVLLQVMDHGTLTDNNGRKADFR
CCCCCCCCCCCHHHHHCCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC
NVIIIMTTNAGAEAMGKSVIGFTNRRETGDEMVDIKRMFTPEFRNRLDAVISFRSLDEEI
CEEEEEECCCCHHHHCCHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHH
IMRVVDKFLMQLEDQLHEKKVDALFTDALRKHLAKHGFDPLMGARPMQRLIQDTIRRALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
DELLFGKLMNGGRVTVDVDAEDKVQLTFDEHPAPRNPNPEAVEVE
HHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]