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The map label for this gene is nhaA [H]

Identifier: 91784726

GI number: 91784726

Start: 3712362

End: 3713366

Strand: Reverse

Name: nhaA [H]

Synonym: Bxe_A1066

Alternate gene names: 91784726

Gene position: 3713366-3712362 (Counterclockwise)

Preceding gene: 91784727

Following gene: 91784723

Centisome position: 75.85

GC content: 61.99

Gene sequence:

>1005_bases
ATGTCCGACAATTTGACTCCCGAGCCGAAGGAACCGTCCCTGACAGGCCGCCCCCGCACGCCTGCCGATGAACCCGGCTG
GGAACGCGCGGCGCTCGAGCGCATTGCGCTTGCCGCGATCAACGAGCAGCGCGCGGCACGGCGCTGGCGAATCTTTTTCC
GCTTCGTGTTTCTGGTCATCTTGCTGCTGGCGATCTGGGCCGCCATCGATTTTTCGGGCGACAAGGTCGCTGCCACCGGC
CGTCATACGGCTATGGTGACGCTTGACGGCGAAATCTCAGCGGATACGAACGCAAACGCCGAAGATATCAACACTGCGCT
AGAAAGCGCATTTGACGACGCGGGCACGGCTGGCGTGATCCTGCGTTGCAATAGCCCCGGTGGCAGCCCGGTGCAGGCAG
GCATCATCTACGACGAAATCCGCCGCCTGCGCGCCAAGTATCCGTCCGTTCCGCTGTATGCCGTCGTCGGCGACATGTGC
GCGTCCGGCGGATATTACGCGGCCGCGGCCGCCGACAAGATCTACGTGGACAAGGCGAGTATCGTCGGTTCGATCGGCGT
GCTGATGGACAGCTTCGGTTTTACCGGCCTGATGGACAAGCTGGGGATTCAGCGGCGTCTGCACACATCGGGTGAGAACA
AGGGCTTTTTCGATCCGTTCTCGCCGGAAACGCCGAAGATGGATGAACATGCGCAAGACATGCTCGATCAGATCCACGCG
CAGTTCATCGACGCGGTCCGCCAGGGGCGCGGCAAGCGGCTGCATGAAACGCCGGACATGTTCTCCGGTCTTTTCTGGAC
AGGGCAAAAAAGCGTCGAACTCGGTCTCGCGGACGGCTTCGGCGACACGGATTATGTGGCCCGCGACCTCTTCAAGGCGC
CGGATATCGTCGATTACACGGTGAAAGAGAGCATTACGGACCGCGTTGCGCGCAAATTCGGCGCAGCCGTCGGCAGCGGC
GCGGTTCATGCGATGGCCCTTGGCGGGAAGCTGAACGTGCGTTGA

Upstream 100 bases:

>100_bases
GATACGCCGGAAGGCCGCGCCGTTTTCTGGCTGCCTGACGGCGAACTGCGCCCCGCCACCCCCTGATTTTTCCTCTTCTT
CGACCTTTCCACTGCACCGC

Downstream 100 bases:

>100_bases
TGTACTGAGGCACTGAGGCTCAGGCGAAAAGCCCTGCGAAAGCCCGCGCGATCGACGATCGCACGGGGCTTTCGCGGTTA
TTTCTCTCCGGCCTCGATCA

Product: family S49 unassigned peptidase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSDNLTPEPKEPSLTGRPRTPADEPGWERAALERIALAAINEQRAARRWRIFFRFVFLVILLLAIWAAIDFSGDKVAATG
RHTAMVTLDGEISADTNANAEDINTALESAFDDAGTAGVILRCNSPGGSPVQAGIIYDEIRRLRAKYPSVPLYAVVGDMC
ASGGYYAAAAADKIYVDKASIVGSIGVLMDSFGFTGLMDKLGIQRRLHTSGENKGFFDPFSPETPKMDEHAQDMLDQIHA
QFIDAVRQGRGKRLHETPDMFSGLFWTGQKSVELGLADGFGDTDYVARDLFKAPDIVDYTVKESITDRVARKFGAAVGSG
AVHAMALGGKLNVR

Sequences:

>Translated_334_residues
MSDNLTPEPKEPSLTGRPRTPADEPGWERAALERIALAAINEQRAARRWRIFFRFVFLVILLLAIWAAIDFSGDKVAATG
RHTAMVTLDGEISADTNANAEDINTALESAFDDAGTAGVILRCNSPGGSPVQAGIIYDEIRRLRAKYPSVPLYAVVGDMC
ASGGYYAAAAADKIYVDKASIVGSIGVLMDSFGFTGLMDKLGIQRRLHTSGENKGFFDPFSPETPKMDEHAQDMLDQIHA
QFIDAVRQGRGKRLHETPDMFSGLFWTGQKSVELGLADGFGDTDYVARDLFKAPDIVDYTVKESITDRVARKFGAAVGSG
AVHAMALGGKLNVR
>Mature_333_residues
SDNLTPEPKEPSLTGRPRTPADEPGWERAALERIALAAINEQRAARRWRIFFRFVFLVILLLAIWAAIDFSGDKVAATGR
HTAMVTLDGEISADTNANAEDINTALESAFDDAGTAGVILRCNSPGGSPVQAGIIYDEIRRLRAKYPSVPLYAVVGDMCA
SGGYYAAAAADKIYVDKASIVGSIGVLMDSFGFTGLMDKLGIQRRLHTSGENKGFFDPFSPETPKMDEHAQDMLDQIHAQ
FIDAVRQGRGKRLHETPDMFSGLFWTGQKSVELGLADGFGDTDYVARDLFKAPDIVDYTVKESITDRVARKFGAAVGSGA
VHAMALGGKLNVR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=216, Percent_Identity=32.4074074074074, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788064, Length=226, Percent_Identity=28.7610619469027, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 36192; Mature: 36061

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNLTPEPKEPSLTGRPRTPADEPGWERAALERIALAAINEQRAARRWRIFFRFVFLVI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLAIWAAIDFSGDKVAATGRHTAMVTLDGEISADTNANAEDINTALESAFDDAGTAGVI
HHHHHHHHHCCCCCEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
LRCNSPGGSPVQAGIIYDEIRRLRAKYPSVPLYAVVGDMCASGGYYAAAAADKIYVDKAS
EEECCCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCEEEEEHHH
IVGSIGVLMDSFGFTGLMDKLGIQRRLHTSGENKGFFDPFSPETPKMDEHAQDMLDQIHA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QFIDAVRQGRGKRLHETPDMFSGLFWTGQKSVELGLADGFGDTDYVARDLFKAPDIVDYT
HHHHHHHHCCCCCCCCCHHHHHHHEECCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHH
VKESITDRVARKFGAAVGSGAVHAMALGGKLNVR
HHHHHHHHHHHHHHHHHCCCCEEEEEECCEECCC
>Mature Secondary Structure 
SDNLTPEPKEPSLTGRPRTPADEPGWERAALERIALAAINEQRAARRWRIFFRFVFLVI
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLAIWAAIDFSGDKVAATGRHTAMVTLDGEISADTNANAEDINTALESAFDDAGTAGVI
HHHHHHHHHCCCCCEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
LRCNSPGGSPVQAGIIYDEIRRLRAKYPSVPLYAVVGDMCASGGYYAAAAADKIYVDKAS
EEECCCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCEEEEEHHH
IVGSIGVLMDSFGFTGLMDKLGIQRRLHTSGENKGFFDPFSPETPKMDEHAQDMLDQIHA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QFIDAVRQGRGKRLHETPDMFSGLFWTGQKSVELGLADGFGDTDYVARDLFKAPDIVDYT
HHHHHHHHCCCCCCCCCHHHHHHHEECCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHH
VKESITDRVARKFGAAVGSGAVHAMALGGKLNVR
HHHHHHHHHHHHHHHHHCCCCEEEEEECCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA