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The map label for this gene is mucB [H]

Identifier: 91784712

GI number: 91784712

Start: 3700650

End: 3701693

Strand: Reverse

Name: mucB [H]

Synonym: Bxe_A1080

Alternate gene names: 91784712

Gene position: 3701693-3700650 (Counterclockwise)

Preceding gene: 91784713

Following gene: 91784711

Centisome position: 75.61

GC content: 61.88

Gene sequence:

>1044_bases
ATGCAGACTCCGCGGTTGAATAAAACGACTATCTGGGGGCGGCTGCCGGCATTTCTGTTCTGCGCAGCCGTATTGCTGTC
CGCCACACCGCGGGTCTTTGCACAAACCGACGATCCGCTCGTCGCCCGTCGCACGGCCGCGGATCTGCTCGATCGCATCC
ATCAGGCCGCGCAGCAGCAAAATTACGAGGGCGCGTTCGTCTACCAGCGCGGCAATTTCGTCCAGACGTCGCGCATTGCG
CACTATGCCACGCGTACAGACGGCGAATTCGAGCAGCTCGAAAGCCTCGACGGCAAGCCGCGCAAAATGCTGCGCCATAA
CGAAGAGCTCTACACGTTCGTGCCGGAGCGGCATCTGTGCGTTGTCGAGAAGCGCCAGAACAAGGACTCGTTCCCCGCGT
TGCTGGCCGTGAGCGGCGAACAGGTGCTGTCGGTCTATCAACCCAGGCTGCTTGGCGACGACCGTGTCGCCGGTGTCGAC
AGCCAGGTGATCGAGCTCGATCCGAAAGACGCCTATCGCTTCGCCTACAAGCTGTGGGCTGACAAGAAAACCGGCCTTCT
GCTGCGTGCCCAGACGCTCGACCCGAGCGGTCAGGTGCTGGAGCAGCTGTCGTTTTCGCAGATTCGCATTGGCGTGCCGG
TGGACAAGGCCGGCATCGTCAACGGTATTCGTAATATGGCGGGGTGGACCGTGGTGCATCCGCCGGTCGAGCCGGTTGAC
ATGGCCGCGCAAGGCTGGCAGATCACGCCGACGGTGTCGGGCTTCCGCAAAATTCGTGAACTGCGCCGTCCTATGGCTGC
GCGCGATCCGGGCCAGCCGACCATTCCGGTGGATCAGGCGGTGTTCTCGGACGGCCTCGCGGCCATTTCGGTGTTCGTCG
AGCCGGTCGAGAACAACACGCGCAAGGAAGGGGCGGGCAGCAGCGGCGCAACGCACGTGCTCGTCAAGCGTCGCGGCGAC
TTCTGGATTACTCTGCTTGGTGAAGTGCCTCAGACCACATTGCAGCAATTTGCGTCTGCCATAGAATACAAAGCTCCGAA
GTAA

Upstream 100 bases:

>100_bases
TATCTGGAAGCTCACCAGCAATTCGCGCAGCAACCGGTCATGCCGGGCTCCATGCCGCTGATTCGCGCTGCCGCTGTTTC
TACGCAAGGCCAATAGTTTG

Downstream 100 bases:

>100_bases
TCCCCCGAATCCTGAATCCCTCGGCTTGCTACGATATGACGACTTTCTCGGTGCGCAAATTCCTCGCGGCCGCGGTGGTA
GCGGCGTGTTTGCCGCTCGT

Product: putative sigma E regulatory protein, MucB/RseB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MQTPRLNKTTIWGRLPAFLFCAAVLLSATPRVFAQTDDPLVARRTAADLLDRIHQAAQQQNYEGAFVYQRGNFVQTSRIA
HYATRTDGEFEQLESLDGKPRKMLRHNEELYTFVPERHLCVVEKRQNKDSFPALLAVSGEQVLSVYQPRLLGDDRVAGVD
SQVIELDPKDAYRFAYKLWADKKTGLLLRAQTLDPSGQVLEQLSFSQIRIGVPVDKAGIVNGIRNMAGWTVVHPPVEPVD
MAAQGWQITPTVSGFRKIRELRRPMAARDPGQPTIPVDQAVFSDGLAAISVFVEPVENNTRKEGAGSSGATHVLVKRRGD
FWITLLGEVPQTTLQQFASAIEYKAPK

Sequences:

>Translated_347_residues
MQTPRLNKTTIWGRLPAFLFCAAVLLSATPRVFAQTDDPLVARRTAADLLDRIHQAAQQQNYEGAFVYQRGNFVQTSRIA
HYATRTDGEFEQLESLDGKPRKMLRHNEELYTFVPERHLCVVEKRQNKDSFPALLAVSGEQVLSVYQPRLLGDDRVAGVD
SQVIELDPKDAYRFAYKLWADKKTGLLLRAQTLDPSGQVLEQLSFSQIRIGVPVDKAGIVNGIRNMAGWTVVHPPVEPVD
MAAQGWQITPTVSGFRKIRELRRPMAARDPGQPTIPVDQAVFSDGLAAISVFVEPVENNTRKEGAGSSGATHVLVKRRGD
FWITLLGEVPQTTLQQFASAIEYKAPK
>Mature_347_residues
MQTPRLNKTTIWGRLPAFLFCAAVLLSATPRVFAQTDDPLVARRTAADLLDRIHQAAQQQNYEGAFVYQRGNFVQTSRIA
HYATRTDGEFEQLESLDGKPRKMLRHNEELYTFVPERHLCVVEKRQNKDSFPALLAVSGEQVLSVYQPRLLGDDRVAGVD
SQVIELDPKDAYRFAYKLWADKKTGLLLRAQTLDPSGQVLEQLSFSQIRIGVPVDKAGIVNGIRNMAGWTVVHPPVEPVD
MAAQGWQITPTVSGFRKIRELRRPMAARDPGQPTIPVDQAVFSDGLAAISVFVEPVENNTRKEGAGSSGATHVLVKRRGD
FWITLLGEVPQTTLQQFASAIEYKAPK

Specific function: Negative regulator of the sigma factor AlgU. Plays a role in the differentiation of P.aeruginosa into the alginate- producing form. Inactivation of mucB causes conversion to mucoidy [H]

COG id: COG3026

COG function: function code T; Negative regulator of sigma E activity

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rseB family [H]

Homologues:

Organism=Escherichia coli, GI1788924, Length=301, Percent_Identity=27.2425249169435, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005588 [H]

Pfam domain/function: PF03888 MucB_RseB [H]

EC number: NA

Molecular weight: Translated: 38676; Mature: 38676

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTPRLNKTTIWGRLPAFLFCAAVLLSATPRVFAQTDDPLVARRTAADLLDRIHQAAQQQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHC
NYEGAFVYQRGNFVQTSRIAHYATRTDGEFEQLESLDGKPRKMLRHNEELYTFVPERHLC
CCCCEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHCCCCCEEECCCCCEE
VVEKRQNKDSFPALLAVSGEQVLSVYQPRLLGDDRVAGVDSQVIELDPKDAYRFAYKLWA
EEECCCCCCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHC
DKKTGLLLRAQTLDPSGQVLEQLSFSQIRIGVPVDKAGIVNGIRNMAGWTVVHPPVEPVD
CCCCCEEEEEECCCCHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHCCCEEECCCCCCHH
MAAQGWQITPTVSGFRKIRELRRPMAARDPGQPTIPVDQAVFSDGLAAISVFVEPVENNT
HHCCCCEECCCHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHCCHHEEHHHHCCCCCCC
RKEGAGSSGATHVLVKRRGDFWITLLGEVPQTTLQQFASAIEYKAPK
CCCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQTPRLNKTTIWGRLPAFLFCAAVLLSATPRVFAQTDDPLVARRTAADLLDRIHQAAQQQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHC
NYEGAFVYQRGNFVQTSRIAHYATRTDGEFEQLESLDGKPRKMLRHNEELYTFVPERHLC
CCCCEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHCCCCCEEECCCCCEE
VVEKRQNKDSFPALLAVSGEQVLSVYQPRLLGDDRVAGVDSQVIELDPKDAYRFAYKLWA
EEECCCCCCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHC
DKKTGLLLRAQTLDPSGQVLEQLSFSQIRIGVPVDKAGIVNGIRNMAGWTVVHPPVEPVD
CCCCCEEEEEECCCCHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHCCCEEECCCCCCHH
MAAQGWQITPTVSGFRKIRELRRPMAARDPGQPTIPVDQAVFSDGLAAISVFVEPVENNT
HHCCCCEECCCHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHCCHHEEHHHHCCCCCCC
RKEGAGSSGATHVLVKRRGDFWITLLGEVPQTTLQQFASAIEYKAPK
CCCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8412698; 8378309; 8444793; 10984043 [H]