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The map label for this gene is pgsA [H]

Identifier: 91784696

GI number: 91784696

Start: 3682541

End: 3683167

Strand: Reverse

Name: pgsA [H]

Synonym: Bxe_A1096

Alternate gene names: 91784696

Gene position: 3683167-3682541 (Counterclockwise)

Preceding gene: 91784697

Following gene: 91784695

Centisome position: 75.23

GC content: 60.93

Gene sequence:

>627_bases
TTGCATCTCACTCGTCAGACGCTGCGCCTGCCCATGCCGTTTAATTTCCCGATTTTCCTGACCTGGCTGCGGATCGTCCT
GATTCCGCTCGTCGTCGGCGTGTTCTATCTGCCCGACATGATGATGAGCCCCGCGCACCGCAATCTGGCGGCCGCGACGA
TCTTCATTCTCGCGGCGTTGACCGACTGGTTCGACGGTTTTCTGGCGCGCAAGTGGAATCAGACCTCGGCGTTCGGCGCG
TTCCTCGATCCGGTCGCCGACAAACTGATGGTGACCGCCGCATTGCTGGTGCTCGTGCAGCTCGCGCGAATCGATTCGGC
GATTGCGCTCGTGATCGTCGGGCGCGAAATCGCGATTTCAGCGCTGCGCGAGTGGATGGCGCAGATCGGCGCGTCGAAGA
GCGTCGCGGTCAATTCTCTCGGCAAGTTCAAGACCGTTTGTCAGATGGTCGCGATTCCCATGCTGCTGTTTTATGGTCCG
CTGCGGTTTGGCGGCGGCGTGGTGGTCGATACGCGCGTGTGGGGCTTGTGGCTCATCTATCTGGCCGCGTTCCTGACGAT
CTGGTCGATGCTCTACTACATGAAGCTCGCATGGCCGCAGATTCGCGAACGCAGCGGTGTGGCCTGA

Upstream 100 bases:

>100_bases
CCGATTCTGTGCTGATTCCCTGCCGATTTCCTGCAAAGCGGCGTGCGTGCGAGGAGCCGCGCGCCGCTTTGCTTGTGGCA
GGCCCTGTGACACGGCACAA

Downstream 100 bases:

>100_bases
TTGGCGTCACGGAGATGCCTCAGGCGTGTCCGAACTTCGCTGACGCATGAGTGAAATCTGTTCAGTAAAAGAGATTGGCA
AAAGGGGTTGACACGTTTCA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MHLTRQTLRLPMPFNFPIFLTWLRIVLIPLVVGVFYLPDMMMSPAHRNLAAATIFILAALTDWFDGFLARKWNQTSAFGA
FLDPVADKLMVTAALLVLVQLARIDSAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTVCQMVAIPMLLFYGP
LRFGGGVVVDTRVWGLWLIYLAAFLTIWSMLYYMKLAWPQIRERSGVA

Sequences:

>Translated_208_residues
MHLTRQTLRLPMPFNFPIFLTWLRIVLIPLVVGVFYLPDMMMSPAHRNLAAATIFILAALTDWFDGFLARKWNQTSAFGA
FLDPVADKLMVTAALLVLVQLARIDSAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTVCQMVAIPMLLFYGP
LRFGGGVVVDTRVWGLWLIYLAAFLTIWSMLYYMKLAWPQIRERSGVA
>Mature_208_residues
MHLTRQTLRLPMPFNFPIFLTWLRIVLIPLVVGVFYLPDMMMSPAHRNLAAATIFILAALTDWFDGFLARKWNQTSAFGA
FLDPVADKLMVTAALLVLVQLARIDSAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTVCQMVAIPMLLFYGP
LRFGGGVVVDTRVWGLWLIYLAAFLTIWSMLYYMKLAWPQIRERSGVA

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=188, Percent_Identity=48.4042553191489, Blast_Score=151, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 23322; Mature: 23322

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLTRQTLRLPMPFNFPIFLTWLRIVLIPLVVGVFYLPDMMMSPAHRNLAAATIFILAAL
CCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TDWFDGFLARKWNQTSAFGAFLDPVADKLMVTAALLVLVQLARIDSAIALVIVGREIAIS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALREWMAQIGASKSVAVNSLGKFKTVCQMVAIPMLLFYGPLRFGGGVVVDTRVWGLWLIY
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
LAAFLTIWSMLYYMKLAWPQIRERSGVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHLTRQTLRLPMPFNFPIFLTWLRIVLIPLVVGVFYLPDMMMSPAHRNLAAATIFILAAL
CCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TDWFDGFLARKWNQTSAFGAFLDPVADKLMVTAALLVLVQLARIDSAIALVIVGREIAIS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALREWMAQIGASKSVAVNSLGKFKTVCQMVAIPMLLFYGPLRFGGGVVVDTRVWGLWLIY
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
LAAFLTIWSMLYYMKLAWPQIRERSGVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]