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The map label for this gene is uvrC [H]

Identifier: 91784697

GI number: 91784697

Start: 3683290

End: 3685551

Strand: Reverse

Name: uvrC [H]

Synonym: Bxe_A1095

Alternate gene names: 91784697

Gene position: 3685551-3683290 (Counterclockwise)

Preceding gene: 91784702

Following gene: 91784696

Centisome position: 75.28

GC content: 65.08

Gene sequence:

>2262_bases
ATGCGCGCGGCACGCGGGGCAAGGCTTCGCAACACCGTCCCACCCAACCGATTCTGCATGACTGAACCCGAAGCAACCGA
CGTTTTCGAGCCGAAGAAAGTGCTCACCCAACTGCCGCATCTGCCCGGCGTCTATCGCTATTACGATACGCACGGCGCGG
TGCTTTACGTGGGCAAGGCACGCGACCTGAAGAAGCGCGTCTCGAGCTACTTCACGAAGACGCAACTGTCGCCGCGCATC
GCGATGATGGTCACGCGCATTGCGCGAGTCGAGACGACCGTCACGCGCTCCGAGGCCGAAGCGCTTCTGCTCGAAAACAA
TCTGATCAAGGCGCTCGCGCCGCGTTACAACATTCTGTTTCGCGACGACAAGTCGTATCCGTACCTCAAGCTCACCGGGC
ACAAGTTTCCACGCATGGCGTACTACCGTGGCGCGGTGGATCGGAAGAATCAGTACTTCGGTCCGTTTCCCAGTGCGTGG
GCGGTGCGCGAGAGCATCCAGATCCTGCAGCGCGTGTTCCAGTTGCGCACCTGCGAAGACTCCGTGTTCAACAACCGCAC
GCGGCCGTGTCTGCTGCATCAGATCGGCCGCTGTACCGCGCCGTGCGTCGCGGCCATCAGCGAAGAAGATTACGCGCGCG
ACGTTGCCAACGCTTCGCGCTTTCTGCTCGGCCGCCAGGGCGAGGTGATGAGCGAGCTCGAACAGAAGATGCACGCGTTC
GCGAGCGAGCTGAAGTTCGAGCAGGCGGCGGCGGTGCGCAACCAGATGAGTTCGCTGTCGACGGTGCTGCATCAGCAGGC
GATCGAAGTCGGCAGCGACAGCGACGTCGATATTCTCGCGGTGGTCGCGCTGGGCGGCCGTGTCTGCGTGAATCTCGCGA
TGGTGCGCGGCGGACGGCATCTGGGCGACAAAGCGTATTTTCCGGCGCATGTGGAAAGCGCGTTGACGGTGGATGAAGGC
GGACTGGAAGACGGCGACGAGCGATTGGCCGATGCCGCTACCGGTCCCGTCTCGCTCGCTGAAGAGGAGGTAGGTGGCGA
GGCGGAGCCGGCCGACACCGCCGATGCTCTGGCGATCGCGCGAGATATGCCGCCGGAAGACGAACAGGACGAGGACGAGG
ACGAGGACGAACAGGACGGCGAACCCGAAGAAGCCGGGTCCGGAGCGGACTCCGACTCCGACTCCGCAAAGCCACGCAAA
GGCCGCGCAACCGGCGGCATCGAATCCGAAGTTCTCGAAGCGTTCATTGCCCAGCATTACCTGGGCAATCGCGTGCCGCC
TGTGCTGGTGGTCAGCCACGCGCCTGCCACACGCGAACTGGTCGATGTGCTGATCGAACAGGCCGGCCACAAGGTGACCG
TGCTGCGCCAGCCGCAAGGACAGCGGCGCGCATGGCTCGTCATGGCCGAGCAGAACGCGCGGCTCGCGCTCGCGCGCCTG
CTCTCGGAACAGGGCTCGCAACAGGCGCGCACGCGCGCGCTCACCGACACGCTCGGAATGGAGTGCGACGATCTTGCACA
TCTGCGCATCGAATGCTTCGACATCAGCCACACGATGGGCGAGGCGACGCAGGCCTCGTGCGTGGTGTATCACCATCACA
AGATGCAGTCCTCGGAATACCGCCGCTACAACATCACCGGCATCACGCCCGGCGACGATTACGCCGCGATGCGCCAGGTG
CTCACGCGCCGCTACGAGAAGATGGTCGCGCAAGCCGCCGCGAATGCCGCCGACGAAGCCGCCGAACTGCAAAGCGACGC
GGCCGCGGACCCGTCGCTTGCGCCGGACGCCGCTGAGCCGGTCGCGGCCGGCGGCGTCCTGCCGACCATCGTGCTGATCG
ACGGCGGCAAGGGCCAGGTCGAAATCGCGCGCCAGGTGTTCACGGAACTGGGTCTCGATACCGGCATGCTGGTCGGTGTC
GCGAAGGGCGAGGGACGCAAGGTCGGCCTCGAAACGCTGATTTTCGCCGATGGCCGCGCGCCGCTCGAACTCGGCAAGGA
AAGCGCCGCGCTGATGCTGGTCGCGCAGATCCGCGACGAAGCGCACCGCTTCGCCATTACCGGCATGCGCGCGAAGCGCG
GCAAAACGCGCCAGACCTCGCGGCTCGAAGAACTCGAAGGCGTGGGCGCAAAGCGGCGCCAACGGCTGCTCGCGCGCTTT
GGCGGACTACGCGGCGTGGTCGCGGCCAGTGTCGAAGATCTGGCGAGCGTCGAAGGTATTTCGCAGGCGCTCGCGGAACA
GATTTACCGTCAGTTGCACTGA

Upstream 100 bases:

>100_bases
ATTTGAGGCAACCGGGTTCGAACGCGCGTGGAATGTTCTAAACTGGCGATTCTAAAGCACCCGTTCACGATTGCGCGCGT
GAGGCATACTCCGGTTCACC

Downstream 100 bases:

>100_bases
GCGCGGCGGGTCCGGCCGGCCGCCGATTCTGTGCTGATTCCCTGCCGATTTCCTGCAAAGCGGCGTGCGTGCGAGGAGCC
GCGCGCCGCTTTGCTTGTGG

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 753; Mature: 753

Protein sequence:

>753_residues
MRAARGARLRNTVPPNRFCMTEPEATDVFEPKKVLTQLPHLPGVYRYYDTHGAVLYVGKARDLKKRVSSYFTKTQLSPRI
AMMVTRIARVETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHKFPRMAYYRGAVDRKNQYFGPFPSAW
AVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCTAPCVAAISEEDYARDVANASRFLLGRQGEVMSELEQKMHAF
ASELKFEQAAAVRNQMSSLSTVLHQQAIEVGSDSDVDILAVVALGGRVCVNLAMVRGGRHLGDKAYFPAHVESALTVDEG
GLEDGDERLADAATGPVSLAEEEVGGEAEPADTADALAIARDMPPEDEQDEDEDEDEQDGEPEEAGSGADSDSDSAKPRK
GRATGGIESEVLEAFIAQHYLGNRVPPVLVVSHAPATRELVDVLIEQAGHKVTVLRQPQGQRRAWLVMAEQNARLALARL
LSEQGSQQARTRALTDTLGMECDDLAHLRIECFDISHTMGEATQASCVVYHHHKMQSSEYRRYNITGITPGDDYAAMRQV
LTRRYEKMVAQAAANAADEAAELQSDAAADPSLAPDAAEPVAAGGVLPTIVLIDGGKGQVEIARQVFTELGLDTGMLVGV
AKGEGRKVGLETLIFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRGKTRQTSRLEELEGVGAKRRQRLLARF
GGLRGVVAASVEDLASVEGISQALAEQIYRQLH

Sequences:

>Translated_753_residues
MRAARGARLRNTVPPNRFCMTEPEATDVFEPKKVLTQLPHLPGVYRYYDTHGAVLYVGKARDLKKRVSSYFTKTQLSPRI
AMMVTRIARVETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHKFPRMAYYRGAVDRKNQYFGPFPSAW
AVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCTAPCVAAISEEDYARDVANASRFLLGRQGEVMSELEQKMHAF
ASELKFEQAAAVRNQMSSLSTVLHQQAIEVGSDSDVDILAVVALGGRVCVNLAMVRGGRHLGDKAYFPAHVESALTVDEG
GLEDGDERLADAATGPVSLAEEEVGGEAEPADTADALAIARDMPPEDEQDEDEDEDEQDGEPEEAGSGADSDSDSAKPRK
GRATGGIESEVLEAFIAQHYLGNRVPPVLVVSHAPATRELVDVLIEQAGHKVTVLRQPQGQRRAWLVMAEQNARLALARL
LSEQGSQQARTRALTDTLGMECDDLAHLRIECFDISHTMGEATQASCVVYHHHKMQSSEYRRYNITGITPGDDYAAMRQV
LTRRYEKMVAQAAANAADEAAELQSDAAADPSLAPDAAEPVAAGGVLPTIVLIDGGKGQVEIARQVFTELGLDTGMLVGV
AKGEGRKVGLETLIFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRGKTRQTSRLEELEGVGAKRRQRLLARF
GGLRGVVAASVEDLASVEGISQALAEQIYRQLH
>Mature_753_residues
MRAARGARLRNTVPPNRFCMTEPEATDVFEPKKVLTQLPHLPGVYRYYDTHGAVLYVGKARDLKKRVSSYFTKTQLSPRI
AMMVTRIARVETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHKFPRMAYYRGAVDRKNQYFGPFPSAW
AVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCTAPCVAAISEEDYARDVANASRFLLGRQGEVMSELEQKMHAF
ASELKFEQAAAVRNQMSSLSTVLHQQAIEVGSDSDVDILAVVALGGRVCVNLAMVRGGRHLGDKAYFPAHVESALTVDEG
GLEDGDERLADAATGPVSLAEEEVGGEAEPADTADALAIARDMPPEDEQDEDEDEDEQDGEPEEAGSGADSDSDSAKPRK
GRATGGIESEVLEAFIAQHYLGNRVPPVLVVSHAPATRELVDVLIEQAGHKVTVLRQPQGQRRAWLVMAEQNARLALARL
LSEQGSQQARTRALTDTLGMECDDLAHLRIECFDISHTMGEATQASCVVYHHHKMQSSEYRRYNITGITPGDDYAAMRQV
LTRRYEKMVAQAAANAADEAAELQSDAAADPSLAPDAAEPVAAGGVLPTIVLIDGGKGQVEIARQVFTELGLDTGMLVGV
AKGEGRKVGLETLIFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRGKTRQTSRLEELEGVGAKRRQRLLARF
GGLRGVVAASVEDLASVEGISQALAEQIYRQLH

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=284, Percent_Identity=46.1267605633803, Blast_Score=283, Evalue=4e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 82439; Mature: 82439

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAARGARLRNTVPPNRFCMTEPEATDVFEPKKVLTQLPHLPGVYRYYDTHGAVLYVGKA
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCEEEEECH
RDLKKRVSSYFTKTQLSPRIAMMVTRIARVETTVTRSEAEALLLENNLIKALAPRYNILF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
RDDKSYPYLKLTGHKFPRMAYYRGAVDRKNQYFGPFPSAWAVRESIQILQRVFQLRTCED
ECCCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SVFNNRTRPCLLHQIGRCTAPCVAAISEEDYARDVANASRFLLGRQGEVMSELEQKMHAF
HHHCCCCCHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ASELKFEQAAAVRNQMSSLSTVLHQQAIEVGSDSDVDILAVVALGGRVCVNLAMVRGGRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCC
LGDKAYFPAHVESALTVDEGGLEDGDERLADAATGPVSLAEEEVGGEAEPADTADALAIA
CCCCCCCCHHHHHHEEECCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHH
RDMPPEDEQDEDEDEDEQDGEPEEAGSGADSDSDSAKPRKGRATGGIESEVLEAFIAQHY
HCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LGNRVPPVLVVSHAPATRELVDVLIEQAGHKVTVLRQPQGQRRAWLVMAEQNARLALARL
HCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHH
LSEQGSQQARTRALTDTLGMECDDLAHLRIECFDISHTMGEATQASCVVYHHHKMQSSEY
HHHCCHHHHHHHHHHHHHCCCCCCHHEEEEEEEECHHHHCCCCCCEEEEEEHHHCCCCCC
RRYNITGITPGDDYAAMRQVLTRRYEKMVAQAAANAADEAAELQSDAAADPSLAPDAAEP
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VAAGGVLPTIVLIDGGKGQVEIARQVFTELGLDTGMLVGVAKGEGRKVGLETLIFADGRA
HHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEECCEEEEEECCCC
PLELGKESAALMLVAQIRDEAHRFAITGMRAKRGKTRQTSRLEELEGVGAKRRQRLLARF
HHHHCCCHHHHHHHHHHHHHHHHEEEECCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
GGLRGVVAASVEDLASVEGISQALAEQIYRQLH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRAARGARLRNTVPPNRFCMTEPEATDVFEPKKVLTQLPHLPGVYRYYDTHGAVLYVGKA
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCEEEEECH
RDLKKRVSSYFTKTQLSPRIAMMVTRIARVETTVTRSEAEALLLENNLIKALAPRYNILF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
RDDKSYPYLKLTGHKFPRMAYYRGAVDRKNQYFGPFPSAWAVRESIQILQRVFQLRTCED
ECCCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SVFNNRTRPCLLHQIGRCTAPCVAAISEEDYARDVANASRFLLGRQGEVMSELEQKMHAF
HHHCCCCCHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ASELKFEQAAAVRNQMSSLSTVLHQQAIEVGSDSDVDILAVVALGGRVCVNLAMVRGGRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCC
LGDKAYFPAHVESALTVDEGGLEDGDERLADAATGPVSLAEEEVGGEAEPADTADALAIA
CCCCCCCCHHHHHHEEECCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHH
RDMPPEDEQDEDEDEDEQDGEPEEAGSGADSDSDSAKPRKGRATGGIESEVLEAFIAQHY
HCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LGNRVPPVLVVSHAPATRELVDVLIEQAGHKVTVLRQPQGQRRAWLVMAEQNARLALARL
HCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHH
LSEQGSQQARTRALTDTLGMECDDLAHLRIECFDISHTMGEATQASCVVYHHHKMQSSEY
HHHCCHHHHHHHHHHHHHCCCCCCHHEEEEEEEECHHHHCCCCCCEEEEEEHHHCCCCCC
RRYNITGITPGDDYAAMRQVLTRRYEKMVAQAAANAADEAAELQSDAAADPSLAPDAAEP
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VAAGGVLPTIVLIDGGKGQVEIARQVFTELGLDTGMLVGVAKGEGRKVGLETLIFADGRA
HHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEECCEEEEEECCCC
PLELGKESAALMLVAQIRDEAHRFAITGMRAKRGKTRQTSRLEELEGVGAKRRQRLLARF
HHHHCCCHHHHHHHHHHHHHHHHEEEECCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
GGLRGVVAASVEDLASVEGISQALAEQIYRQLH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA