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The map label for this gene is amnH

Identifier: 91784643

GI number: 91784643

Start: 3633829

End: 3634770

Strand: Reverse

Name: amnH

Synonym: Bxe_A1151

Alternate gene names: 91784643

Gene position: 3634770-3633829 (Counterclockwise)

Preceding gene: 91784644

Following gene: 91784642

Centisome position: 74.24

GC content: 59.98

Gene sequence:

>942_bases
ATGACCCGAAAATTCAAAGCCGCCATCATCGGCAGCGGAAACATCGGCACGGACCTGATGATCAAGATCATGCGTCACGG
CCGTCACATCGAAGTAGGGGCCATGGTGGGGATCGACCCTGCCTCGGACGGTCTTGCCCGTGCTTCTCGCCTGGGCGTAG
GCACCACACACGAAGGTGTAGAGGGTTTGACGCGTCTGCCCATCTTCGAGGAAATCGACTTCGTGTTCGATGCTACGAGC
GCCGGGGCTCACGTCCACAACGATGCACTGCTGCGCAAGTACAAACCCGGTATCCGCGTCATTGACCTGACGCCGGCCGC
CATCGGTCCGTACTGCATCCCCGTAGTCAATGGCAAACAGAACTTGGATGCGCTGAACGTCAACATGGTGACTTGCGGCG
GCCAGGCAACTGTCCCCATGGTAGCCGCGGTCTCTCGCGTGACCCAGGTCCACTATGGCGAGATCGTGGCTTCTATCGCT
AGTAAGAGTGCCGGGCCAGGGACTCGGGCCAACATCGACGAGTTCACCGAGACAACCTCAAAGGCCATTGAAGTTGTGGG
TGGCGCATCGAAAGGCAAGGCCATCATCGTGTTGAACCCCGCCGATCCGCCCTTGATCATGCGCGACACCGTGTACACGC
TCAGCGACGTGGCTGACGAAGCAGCTATTGCCGATTCGGTTGCCCGGATGGCCGCCGATGTCCAGAGCTACGTGCCAGGA
TATCGATTGAAGCAGACCGTGCAGTTTGATCGTGTCGAGAACCTGAACGTGCCAGGCGTGGGCCGCATCTCCGGCCTGAA
AACCAGCATTTTCCTGGAAGTCGAAGGCGCAGCGCACTACTTGCCGGCTTACGCGGGAAATCTCGACATCATGACCAGCG
CCGGCCTTCGCACAGCCGAACAAATGGCAGCACGGATGACGGCCGGGACGGTCGCCGCCTGA

Upstream 100 bases:

>100_bases
CATGCAGGGCTTGGGGAGCGTTAGCTTTCAACTGGTTTGATTGGGGTCTTGCGCGTCAAGCGCACCACCGCACTTGCAGC
GTCTATATCTGGAGTTCTCT

Downstream 100 bases:

>100_bases
ACGAGGAGCACAACGATGAGCATCAACGGGAACGCCGCAGCGTCCAAGCTTTATATTTCCGACGTCACTTTGCGCGATGG
AAGCCACGCTATCCGCCATC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] 2

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTRKFKAAIIGSGNIGTDLMIKIMRHGRHIEVGAMVGIDPASDGLARASRLGVGTTHEGVEGLTRLPIFEEIDFVFDATS
AGAHVHNDALLRKYKPGIRVIDLTPAAIGPYCIPVVNGKQNLDALNVNMVTCGGQATVPMVAAVSRVTQVHYGEIVASIA
SKSAGPGTRANIDEFTETTSKAIEVVGGASKGKAIIVLNPADPPLIMRDTVYTLSDVADEAAIADSVARMAADVQSYVPG
YRLKQTVQFDRVENLNVPGVGRISGLKTSIFLEVEGAAHYLPAYAGNLDIMTSAGLRTAEQMAARMTAGTVAA

Sequences:

>Translated_313_residues
MTRKFKAAIIGSGNIGTDLMIKIMRHGRHIEVGAMVGIDPASDGLARASRLGVGTTHEGVEGLTRLPIFEEIDFVFDATS
AGAHVHNDALLRKYKPGIRVIDLTPAAIGPYCIPVVNGKQNLDALNVNMVTCGGQATVPMVAAVSRVTQVHYGEIVASIA
SKSAGPGTRANIDEFTETTSKAIEVVGGASKGKAIIVLNPADPPLIMRDTVYTLSDVADEAAIADSVARMAADVQSYVPG
YRLKQTVQFDRVENLNVPGVGRISGLKTSIFLEVEGAAHYLPAYAGNLDIMTSAGLRTAEQMAARMTAGTVAA
>Mature_312_residues
TRKFKAAIIGSGNIGTDLMIKIMRHGRHIEVGAMVGIDPASDGLARASRLGVGTTHEGVEGLTRLPIFEEIDFVFDATSA
GAHVHNDALLRKYKPGIRVIDLTPAAIGPYCIPVVNGKQNLDALNVNMVTCGGQATVPMVAAVSRVTQVHYGEIVASIAS
KSAGPGTRANIDEFTETTSKAIEVVGGASKGKAIIVLNPADPPLIMRDTVYTLSDVADEAAIADSVARMAADVQSYVPGY
RLKQTVQFDRVENLNVPGVGRISGLKTSIFLEVEGAAHYLPAYAGNLDIMTSAGLRTAEQMAARMTAGTVAA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=306, Percent_Identity=74.5098039215686, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH2_BURXL (Q13VU2)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_559849.1
- ProteinModelPortal:   Q13VU2
- SMR:   Q13VU2
- GeneID:   4002974
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A1151
- HOGENOM:   HBG300125
- OMA:   GLEVIGG
- ProtClustDB:   PRK08300
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 32856; Mature: 32725

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: BINDING 287-287

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKFKAAIIGSGNIGTDLMIKIMRHGRHIEVGAMVGIDPASDGLARASRLGVGTTHEGV
CCCEEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCHHH
EGLTRLPIFEEIDFVFDATSAGAHVHNDALLRKYKPGIRVIDLTPAAIGPYCIPVVNGKQ
HHHHCCCCHHHHHHEEECCCCCCEECHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCC
NLDALNVNMVTCGGQATVPMVAAVSRVTQVHYGEIVASIASKSAGPGTRANIDEFTETTS
CCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KAIEVVGGASKGKAIIVLNPADPPLIMRDTVYTLSDVADEAAIADSVARMAADVQSYVPG
HHHHHHCCCCCCCEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YRLKQTVQFDRVENLNVPGVGRISGLKTSIFLEVEGAAHYLPAYAGNLDIMTSAGLRTAE
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHCCCEEEEECCCCHHHH
QMAARMTAGTVAA
HHHHHHHCCCCCC
>Mature Secondary Structure 
TRKFKAAIIGSGNIGTDLMIKIMRHGRHIEVGAMVGIDPASDGLARASRLGVGTTHEGV
CCEEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCHHH
EGLTRLPIFEEIDFVFDATSAGAHVHNDALLRKYKPGIRVIDLTPAAIGPYCIPVVNGKQ
HHHHCCCCHHHHHHEEECCCCCCEECHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCC
NLDALNVNMVTCGGQATVPMVAAVSRVTQVHYGEIVASIASKSAGPGTRANIDEFTETTS
CCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KAIEVVGGASKGKAIIVLNPADPPLIMRDTVYTLSDVADEAAIADSVARMAADVQSYVPG
HHHHHHCCCCCCCEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YRLKQTVQFDRVENLNVPGVGRISGLKTSIFLEVEGAAHYLPAYAGNLDIMTSAGLRTAE
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHCCCEEEEECCCCHHHH
QMAARMTAGTVAA
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA