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The map label for this gene is rnr [H]

Identifier: 91783278

GI number: 91783278

Start: 2120816

End: 2123317

Strand: Direct

Name: rnr [H]

Synonym: Bxe_A2540

Alternate gene names: 91783278

Gene position: 2120816-2123317 (Clockwise)

Preceding gene: 91783274

Following gene: 91783279

Centisome position: 43.32

GC content: 64.55

Gene sequence:

>2502_bases
ATGCAACGAGAAAAAATCATCGACAAGCCCTTGAGCAAATTCCCGTATCCGATTCCAAGCCGCGAAGAAATCCTGGGCGT
CCTGCGCACGAGTGAAGCGCCGCTTGCCGCGAACGACATCGCCGAAGCCTTGTCGATCAAGCGCCAGGAGCGCGAAGGAT
TTTTCAAGCGCTTAGGCGCGATGGAGCGCGACGGCCAGATCCGGCTCGATCAGCGCAATCTCTATCAGTTGACTCATCCG
TCGAACTTCGTCGCCGGCCGCGTGCAAGGTCATCGCGACGGCTACGGTTTTCTGGTTCGCGACGACGGTCAGGACGATCT
GTTCCTGCCCACCGGCGAGATGCAGAAGGTCATGCACAACGACCGCGTGCTTGCGCGCATCGTCGGCTATGACCGGCGCG
GCCGTCCGGAAGGGCATATCGTCGAAGTCACGGATCGCGCCAACAAGCGCGTGATCGGCCGCCTGCTCAACGAGAACGGC
GCGCTGATCGTCGCGCCCGAAGACAAGCGCATCGGCCACGACATTCTGATCACGCAGAACACCAAGAAGGCCAAGGTCGG
CCAGGTGGTGGTGGTCGAGCTGACCGATTTCCCGAGCCGTCATTCGCAGCCGCTCGGCCGCGTGGTGGAAGTGCTCGGCG
ATATCGACGACCCCGGCATGGAAATCGAAATCGCGGTGCGCAAATACGGCGTGCCGCACGAATTCAGCCAGGCCGCGCTC
GACGAAGCCTCGCGGCTGCCCGACGAAGTGCGCCCGGTCGACGCGCGTCATCGCATCGATCTGCGCGACGTGCCGCTCGT
CACGATCGACGGCGAAGACGCCCGCGACTTCGACGACGCCGTGTACTGCGAGCCGGTTCAGGTCGGCCGCGGCGAGGGCT
TCCGCCTGATCGTCGCGATCGCGGACGTCTCGCACTACGTGCATCCGAAGAGCGGCCTCGACGCCGACGCGATCGAACGC
AGCACCTCGGTGTATTTCCCGCGCCGCGTGATTCCCATGCTGCCGGAGAAACTGTCGAACGGTTTGTGCTCGCTGAATCC
GAACGTCGACCGTTGCGTGCTGGTGTGCGACATGATCGTCACCACGCGCGGCGAGGTGAAGGCGTATCAGTTCTATCCCG
GCGTGATGCACTCGGCCGCACGGCTCACCTATACGGAAGTCGCCGCGGTATTGAAGAACACCAAGGGCCCGGAGGCCGCG
CGCCGCGCCGCGTTGCTGCCGCAACTGCAGAATCTGTACGGCGTGTACAAGTCGCTGTTCGCCGCGCGCCAGAAACGCGG
TGCGATCGACTTCGATACGACCGAGACGTATATCGTCTGCAATGCGCAGGGCAAGATCGAACAGATCATTCCGCGCACGC
GGAACGACGCGCACAAGCTGATCGAGGAATGCATGCTGGCCGCGAACGTCTGCGCGGCCGACTTCCTCAAGCGCAACAAA
CATCCGGGGCTGTTCCGCGTGCACGCCGGGCCGACCGCGGAAAAGCTCGAGAATCTGCGCACCTTCCTGCGCGGCATGGG
CCTCACGCTCAACGGCGGCGACAAGCCGCACGCGAGCGACTACGCCGCGCTGATGGCGCAAATCCGCGAGCGGCCCGACG
CGCAGATGCTGCAAACCATGCTGCTGCGCTCCATGCAGCAGGCGGTATACAGCCCGGACAACATCGGCCACTTCGGTCTC
GCGTACGAGGCGTATGCGCACTTCACGAGCCCGATTCGCCGTTATCCCGATCTGCTCACGCACCGCGCGATCTACGCGAT
CCTGCAAGGCCGCAAGTATCAGCCGGAGCCGCCGCAAGGCGTCGAGCTGAATACGGCGCTCTCGCCACGCGCTCGCGCCA
TGCAGCAGGCCGACGACGAAAAGCGCGGCCGCGTGCGTGGCAACAACGTGGCGATCTGGGAAGAACTCGGTCTGCATTGC
TCGGCCAACGAACGCCGCGCCGACGAAGCCTCGCGCGACGTCGAAGCCTGGTTGAAGTGCTACTTCATGCGCGACAAGCT
CGGCGAAGAGTACGGCGGCATGGTGAACGGCGTCACGTCGTTCGGCATTTTCGTGCAGCTCGATTCGCTGTTCATTGAAG
GCCTCGTGCACGTCACGGAACTCGGCTCGGACTACTTCCAGTACGACGAGATCAAGAACGAGTTGCGCGGCGAGCGCACC
GGCATCCGTTATCGCCTGTCGGATCGCGTGCGGGTGCAGGTAAGCCGTGTCGATCTCGACGCGCGCAAGATCGACTTCCG
GCTCGTGCGCGACACGCCGATCAAGCCGCCTTTGGTGCGTGGGTCGGGGACCGACAAGTCGTCCGCTGAAAATGGCGGTG
CACGCGTGCGTGCGCTGCCGCCGGTGGAAGGTGGAGCGGCAACGCAGGGCGCGCGTCGCAAGCGCGCCGCGCCCGCGCAA
ACCGAGGCGGTCAAGGAAGCACGCGCGGCGCGCGGCGCGGCGAAGAAGCACGGCGCCGCGACCAAATCGGCGTCGAAACC
GCAGGCACGCAAGAAGCGCTGA

Upstream 100 bases:

>100_bases
TTTTCTGTGCATTTGCAGGTGCAATTCAAGCGCGACCGAAGCGCAAGCGAAGCGCGCCGTCATCGCTTTCCAAGCCGAGC
CACATCGCAGACCGACGTCC

Downstream 100 bases:

>100_bases
AGCCGGCTGACTGCCTGAACCGCGCGCATCGGGCACGTAGCAACGTGCCGGTTGCGCGCGGTCTGCGTTTTATCGCCGCG
AGGCATTCGAGCGCGGCGGC

Product: 3'-5' exoribonuclease, VacB and RNase II

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 833; Mature: 833

Protein sequence:

>833_residues
MQREKIIDKPLSKFPYPIPSREEILGVLRTSEAPLAANDIAEALSIKRQEREGFFKRLGAMERDGQIRLDQRNLYQLTHP
SNFVAGRVQGHRDGYGFLVRDDGQDDLFLPTGEMQKVMHNDRVLARIVGYDRRGRPEGHIVEVTDRANKRVIGRLLNENG
ALIVAPEDKRIGHDILITQNTKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQAAL
DEASRLPDEVRPVDARHRIDLRDVPLVTIDGEDARDFDDAVYCEPVQVGRGEGFRLIVAIADVSHYVHPKSGLDADAIER
STSVYFPRRVIPMLPEKLSNGLCSLNPNVDRCVLVCDMIVTTRGEVKAYQFYPGVMHSAARLTYTEVAAVLKNTKGPEAA
RRAALLPQLQNLYGVYKSLFAARQKRGAIDFDTTETYIVCNAQGKIEQIIPRTRNDAHKLIEECMLAANVCAADFLKRNK
HPGLFRVHAGPTAEKLENLRTFLRGMGLTLNGGDKPHASDYAALMAQIRERPDAQMLQTMLLRSMQQAVYSPDNIGHFGL
AYEAYAHFTSPIRRYPDLLTHRAIYAILQGRKYQPEPPQGVELNTALSPRARAMQQADDEKRGRVRGNNVAIWEELGLHC
SANERRADEASRDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDSLFIEGLVHVTELGSDYFQYDEIKNELRGERT
GIRYRLSDRVRVQVSRVDLDARKIDFRLVRDTPIKPPLVRGSGTDKSSAENGGARVRALPPVEGGAATQGARRKRAAPAQ
TEAVKEARAARGAAKKHGAATKSASKPQARKKR

Sequences:

>Translated_833_residues
MQREKIIDKPLSKFPYPIPSREEILGVLRTSEAPLAANDIAEALSIKRQEREGFFKRLGAMERDGQIRLDQRNLYQLTHP
SNFVAGRVQGHRDGYGFLVRDDGQDDLFLPTGEMQKVMHNDRVLARIVGYDRRGRPEGHIVEVTDRANKRVIGRLLNENG
ALIVAPEDKRIGHDILITQNTKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQAAL
DEASRLPDEVRPVDARHRIDLRDVPLVTIDGEDARDFDDAVYCEPVQVGRGEGFRLIVAIADVSHYVHPKSGLDADAIER
STSVYFPRRVIPMLPEKLSNGLCSLNPNVDRCVLVCDMIVTTRGEVKAYQFYPGVMHSAARLTYTEVAAVLKNTKGPEAA
RRAALLPQLQNLYGVYKSLFAARQKRGAIDFDTTETYIVCNAQGKIEQIIPRTRNDAHKLIEECMLAANVCAADFLKRNK
HPGLFRVHAGPTAEKLENLRTFLRGMGLTLNGGDKPHASDYAALMAQIRERPDAQMLQTMLLRSMQQAVYSPDNIGHFGL
AYEAYAHFTSPIRRYPDLLTHRAIYAILQGRKYQPEPPQGVELNTALSPRARAMQQADDEKRGRVRGNNVAIWEELGLHC
SANERRADEASRDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDSLFIEGLVHVTELGSDYFQYDEIKNELRGERT
GIRYRLSDRVRVQVSRVDLDARKIDFRLVRDTPIKPPLVRGSGTDKSSAENGGARVRALPPVEGGAATQGARRKRAAPAQ
TEAVKEARAARGAAKKHGAATKSASKPQARKKR
>Mature_833_residues
MQREKIIDKPLSKFPYPIPSREEILGVLRTSEAPLAANDIAEALSIKRQEREGFFKRLGAMERDGQIRLDQRNLYQLTHP
SNFVAGRVQGHRDGYGFLVRDDGQDDLFLPTGEMQKVMHNDRVLARIVGYDRRGRPEGHIVEVTDRANKRVIGRLLNENG
ALIVAPEDKRIGHDILITQNTKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQAAL
DEASRLPDEVRPVDARHRIDLRDVPLVTIDGEDARDFDDAVYCEPVQVGRGEGFRLIVAIADVSHYVHPKSGLDADAIER
STSVYFPRRVIPMLPEKLSNGLCSLNPNVDRCVLVCDMIVTTRGEVKAYQFYPGVMHSAARLTYTEVAAVLKNTKGPEAA
RRAALLPQLQNLYGVYKSLFAARQKRGAIDFDTTETYIVCNAQGKIEQIIPRTRNDAHKLIEECMLAANVCAADFLKRNK
HPGLFRVHAGPTAEKLENLRTFLRGMGLTLNGGDKPHASDYAALMAQIRERPDAQMLQTMLLRSMQQAVYSPDNIGHFGL
AYEAYAHFTSPIRRYPDLLTHRAIYAILQGRKYQPEPPQGVELNTALSPRARAMQQADDEKRGRVRGNNVAIWEELGLHC
SANERRADEASRDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDSLFIEGLVHVTELGSDYFQYDEIKNELRGERT
GIRYRLSDRVRVQVSRVDLDARKIDFRLVRDTPIKPPLVRGSGTDKSSAENGGARVRALPPVEGGAATQGARRKRAAPAQ
TEAVKEARAARGAAKKHGAATKSASKPQARKKR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=484, Percent_Identity=29.9586776859504, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI190014623, Length=480, Percent_Identity=30, Blast_Score=185, Evalue=2e-46,
Organism=Homo sapiens, GI134288890, Length=434, Percent_Identity=30.6451612903226, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI219521928, Length=655, Percent_Identity=25.8015267175572, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI19115966, Length=655, Percent_Identity=25.8015267175572, Blast_Score=151, Evalue=3e-36,
Organism=Escherichia coli, GI87082383, Length=754, Percent_Identity=48.5411140583554, Blast_Score=689, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=680, Percent_Identity=25.8823529411765, Blast_Score=192, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI212645896, Length=413, Percent_Identity=30.0242130750605, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17553506, Length=464, Percent_Identity=28.6637931034483, Blast_Score=149, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6324552, Length=666, Percent_Identity=23.8738738738739, Blast_Score=130, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24649634, Length=474, Percent_Identity=29.1139240506329, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24654592, Length=418, Percent_Identity=29.4258373205742, Blast_Score=143, Evalue=6e-34,
Organism=Drosophila melanogaster, GI19922976, Length=418, Percent_Identity=29.4258373205742, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24654597, Length=418, Percent_Identity=29.4258373205742, Blast_Score=142, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 93091; Mature: 93091

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQREKIIDKPLSKFPYPIPSREEILGVLRTSEAPLAANDIAEALSIKRQEREGFFKRLGA
CCCHHHHHCHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
MERDGQIRLDQRNLYQLTHPSNFVAGRVQGHRDGYGFLVRDDGQDDLFLPTGEMQKVMHN
CCCCCCEEECCCCEEEECCCCCCEEECCCCCCCCEEEEEEECCCCCEEECCHHHHHHHHC
DRVLARIVGYDRRGRPEGHIVEVTDRANKRVIGRLLNENGALIVAPEDKRIGHDILITQN
CHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEEECC
TKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQAAL
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHH
DEASRLPDEVRPVDARHRIDLRDVPLVTIDGEDARDFDDAVYCEPVQVGRGEGFRLIVAI
HHHHCCCHHCCCCCCHHCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEE
ADVSHYVHPKSGLDADAIERSTSVYFPRRVIPMLPEKLSNGLCSLNPNVDRCVLVCDMIV
ECHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCEECCCCHHHHHHHHHHHH
TTRGEVKAYQFYPGVMHSAARLTYTEVAAVLKNTKGPEAARRAALLPQLQNLYGVYKSLF
HCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AARQKRGAIDFDTTETYIVCNAQGKIEQIIPRTRNDAHKLIEECMLAANVCAADFLKRNK
HHHHHCCCCCCCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
HPGLFRVHAGPTAEKLENLRTFLRGMGLTLNGGDKPHASDYAALMAQIRERPDAQMLQTM
CCCEEEEECCCCHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
LLRSMQQAVYSPDNIGHFGLAYEAYAHFTSPIRRYPDLLTHRAIYAILQGRKYQPEPPQG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VELNTALSPRARAMQQADDEKRGRVRGNNVAIWEELGLHCSANERRADEASRDVEAWLKC
EEECCCCCHHHHHHHHCCHHHCCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHH
YFMRDKLGEEYGGMVNGVTSFGIFVQLDSLFIEGLVHVTELGSDYFQYDEIKNELRGERT
HHHHHHHCHHHCCHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
GIRYRLSDRVRVQVSRVDLDARKIDFRLVRDTPIKPPLVRGSGTDKSSAENGGARVRALP
CEEEEECCCEEEEEEEECCCCCEEEEEEEECCCCCCCEECCCCCCCCCCCCCCCEEEECC
PVEGGAATQGARRKRAAPAQTEAVKEARAARGAAKKHGAATKSASKPQARKKR
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHCHHHHCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MQREKIIDKPLSKFPYPIPSREEILGVLRTSEAPLAANDIAEALSIKRQEREGFFKRLGA
CCCHHHHHCHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
MERDGQIRLDQRNLYQLTHPSNFVAGRVQGHRDGYGFLVRDDGQDDLFLPTGEMQKVMHN
CCCCCCEEECCCCEEEECCCCCCEEECCCCCCCCEEEEEEECCCCCEEECCHHHHHHHHC
DRVLARIVGYDRRGRPEGHIVEVTDRANKRVIGRLLNENGALIVAPEDKRIGHDILITQN
CHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEEECC
TKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSQAAL
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHH
DEASRLPDEVRPVDARHRIDLRDVPLVTIDGEDARDFDDAVYCEPVQVGRGEGFRLIVAI
HHHHCCCHHCCCCCCHHCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEE
ADVSHYVHPKSGLDADAIERSTSVYFPRRVIPMLPEKLSNGLCSLNPNVDRCVLVCDMIV
ECHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCEECCCCHHHHHHHHHHHH
TTRGEVKAYQFYPGVMHSAARLTYTEVAAVLKNTKGPEAARRAALLPQLQNLYGVYKSLF
HCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AARQKRGAIDFDTTETYIVCNAQGKIEQIIPRTRNDAHKLIEECMLAANVCAADFLKRNK
HHHHHCCCCCCCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
HPGLFRVHAGPTAEKLENLRTFLRGMGLTLNGGDKPHASDYAALMAQIRERPDAQMLQTM
CCCEEEEECCCCHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
LLRSMQQAVYSPDNIGHFGLAYEAYAHFTSPIRRYPDLLTHRAIYAILQGRKYQPEPPQG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VELNTALSPRARAMQQADDEKRGRVRGNNVAIWEELGLHCSANERRADEASRDVEAWLKC
EEECCCCCHHHHHHHHCCHHHCCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHH
YFMRDKLGEEYGGMVNGVTSFGIFVQLDSLFIEGLVHVTELGSDYFQYDEIKNELRGERT
HHHHHHHCHHHCCHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
GIRYRLSDRVRVQVSRVDLDARKIDFRLVRDTPIKPPLVRGSGTDKSSAENGGARVRALP
CEEEEECCCEEEEEEEECCCCCEEEEEEEECCCCCCCEECCCCCCCCCCCCCCCEEEECC
PVEGGAATQGARRKRAAPAQTEAVKEARAARGAAKKHGAATKSASKPQARKKR
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHCHHHHCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]