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The map label for this gene is rmlC [H]

Identifier: 91782843

GI number: 91782843

Start: 1624030

End: 1624581

Strand: Direct

Name: rmlC [H]

Synonym: Bxe_A2982

Alternate gene names: 91782843

Gene position: 1624030-1624581 (Clockwise)

Preceding gene: 91782842

Following gene: 91782845

Centisome position: 33.17

GC content: 61.96

Gene sequence:

>552_bases
ATGGGCAACAAGGTGATCGCGACGGCATTGCCGGAGGTAAAGCTCATCGAGCCCGAAGTGTTCTGCGACGAATTCGGCTT
CTGCTTCGAGAGCTTCAGCGAGGACGAGTTTATCGCGGACGTCTCGCAAGCGTTCCAGTTCGTGCAGGACCGCCATTCGA
GCGCGGTGCGTGGCGTGTTACGCGGGTTGCACTATCAGGTGCAGCGTCCTCAAGGGCGGCTCATGCGGGTCGTCGTGGGC
GAAGTGTTCGGCGTTGCGGTGGACGTGCGGCTCAATTCGCCGAACTTCGGCAAGTGGTGCGGGGCGGATCTGAGCGCGGC
CAACCACCGCCAGATCTGGGTGCCGCCGGGCTTCGCGCATGGTTTCGTGGTGCTGTCCGACGTCGCCGAGTGTTTGTGGA
AGACCACGGAATACTGGTTTCCCGAACTGGAGCGCTGCATTCTGTGGAGCGATCCCGACATCGGCATTGAATGGCCCATC
GATTTCGAGCCGATTCTCGGCGCGAAGGATGCCGCGGGCCGGCGCCTTTACGAAGCGGAAAACATCGCCTGA

Upstream 100 bases:

>100_bases
GGCGCCCGTGCCGGCAGCAGCGGCGCGCCTGATGAGAACTGGACGCGGCCGTCGTGTTGGCCGCGTTTTCGCCGGTCAGG
CTTCTTGAGAGTGCAGCGGC

Downstream 100 bases:

>100_bases
GCGCAGCGTAGTGCCGCGCGTTGCAACGGGCGTGCACCGCCTCTGTCCTGCAACGCGATTCAGCGCGTCGCGACCACGGC
ACCGACGCTCGCGGTCACCA

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MGNKVIATALPEVKLIEPEVFCDEFGFCFESFSEDEFIADVSQAFQFVQDRHSSAVRGVLRGLHYQVQRPQGRLMRVVVG
EVFGVAVDVRLNSPNFGKWCGADLSAANHRQIWVPPGFAHGFVVLSDVAECLWKTTEYWFPELERCILWSDPDIGIEWPI
DFEPILGAKDAAGRRLYEAENIA

Sequences:

>Translated_183_residues
MGNKVIATALPEVKLIEPEVFCDEFGFCFESFSEDEFIADVSQAFQFVQDRHSSAVRGVLRGLHYQVQRPQGRLMRVVVG
EVFGVAVDVRLNSPNFGKWCGADLSAANHRQIWVPPGFAHGFVVLSDVAECLWKTTEYWFPELERCILWSDPDIGIEWPI
DFEPILGAKDAAGRRLYEAENIA
>Mature_182_residues
GNKVIATALPEVKLIEPEVFCDEFGFCFESFSEDEFIADVSQAFQFVQDRHSSAVRGVLRGLHYQVQRPQGRLMRVVVGE
VFGVAVDVRLNSPNFGKWCGADLSAANHRQIWVPPGFAHGFVVLSDVAECLWKTTEYWFPELERCILWSDPDIGIEWPID
FEPILGAKDAAGRRLYEAENIA

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=168, Percent_Identity=48.8095238095238, Blast_Score=159, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17550412, Length=158, Percent_Identity=42.4050632911392, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20651; Mature: 20519

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNKVIATALPEVKLIEPEVFCDEFGFCFESFSEDEFIADVSQAFQFVQDRHSSAVRGVL
CCCEEEEECCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RGLHYQVQRPQGRLMRVVVGEVFGVAVDVRLNSPNFGKWCGADLSAANHRQIWVPPGFAH
HHHHHEEECCHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCH
GFVVLSDVAECLWKTTEYWFPELERCILWSDPDIGIEWPIDFEPILGAKDAAGRRLYEAE
HHHHHHHHHHHHHHHHHHCCHHHCEEEEECCCCCCEECCCCCCCCCCCCCCCCCEEHHHC
NIA
CCC
>Mature Secondary Structure 
GNKVIATALPEVKLIEPEVFCDEFGFCFESFSEDEFIADVSQAFQFVQDRHSSAVRGVL
CCEEEEECCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RGLHYQVQRPQGRLMRVVVGEVFGVAVDVRLNSPNFGKWCGADLSAANHRQIWVPPGFAH
HHHHHEEECCHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCH
GFVVLSDVAECLWKTTEYWFPELERCILWSDPDIGIEWPIDFEPILGAKDAAGRRLYEAE
HHHHHHHHHHHHHHHHHHCCHHHCEEEEECCCCCCEECCCCCCCCCCCCCCCCCEEHHHC
NIA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]