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The map label for this gene is lrhA [H]

Identifier: 91782845

GI number: 91782845

Start: 1625613

End: 1626548

Strand: Direct

Name: lrhA [H]

Synonym: Bxe_A2980

Alternate gene names: 91782845

Gene position: 1625613-1626548 (Clockwise)

Preceding gene: 91782843

Following gene: 91782846

Centisome position: 33.2

GC content: 68.48

Gene sequence:

>936_bases
ATGCCCACTTCAAGAACCCTTATGAGCCGAGATCTCGACAGCAGCTTGCTGCGCACGTTCGTCACCGTGGCGGAGACGGG
GGCGATGGGTGTCGCGGCAACGCGGCTCGCGCGCACTCAGGCCGCGGTGAGCATGCAATTGCGCCGGCTCGAAGACGAAC
TCGGCCAGCGTTTGCTCGACCGCTCGCCGCGCGGTGTGCAACTCACCGAAGCCGGGCATCTGCTGCTGCCCTACGCGCAC
GCGATTCTCGGCGCGGGTGCCGACGCGCGCCGCGCGCTGAGCGCCGGGCAGGTGTCCGGCACCGTGCGGCTCGGCATGCT
GGAGGATATTGCGGTCGGTCGCTTGCCGCGCGCGCTGCGGCGCTTTTCGATTGCTTATCCGCAAGTGGCGCTGGAAATCG
TGGTCGACAGCAGTGTCGCGTTGTCGAACCGGCTCGCGGACAGCAGCCTCGATGTCGTGGTCGGCGATCCCGCGCTGGTC
GACGCGGCGCCGCTGCTGACCTGGCGGCAGCCGCTCTTCTGGGTCGGCGCTCGCGGCTTTGGCCGGGAAGTGGAGGCGCC
TTTGCCGGTGGTGGCATTCGGCGGTGCGTGTCTGTGGCAGCAGCAGGTTCTGGCGGCGTTGCGGCGCGCGGGAATTGCGT
GGCGCATCGTGTGCACCAGCACCAGTCTGCCGGCCGTGCAATCCGCCGTTGAAGCCGGGCTCGGCGTGTCGGTGCTGCTC
GACGGCAACATCCGTTCGGAATCGATGCGCGTGCTGGGCCAGGCCGATGGTTTGCCCGACGCGCCCACCGCGGACTTCGG
GCTTTTCACGCGCGAAGTGCCGGGCGCACAGGCAGCGGCCGTGCAAACCCTGCAAACGTTCCTCTGCGAGGAATTGCATC
TCGGCCTGCGCGAAGGCGAGCCGTCGCTCATGCCGGTTTCGTCCGCATCGGGATGA

Upstream 100 bases:

>100_bases
GAATGGTCGTGTCCTGCATAGGGGTGGCCTGGTGCCCGATTGGAATTCGCTGACGCTATCTTATCGGTGCAGGCAGTATT
AAGATAACTTGATATTTCTT

Downstream 100 bases:

>100_bases
TGCGCGGGCCGCTCTTTTTACGTGGGTTTTTACGACATTTTTTCTTGAGACGCACCCACGCGAAATCTACACTTCGGGCA
TCCTGATTCCGCGAGGTGCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MPTSRTLMSRDLDSSLLRTFVTVAETGAMGVAATRLARTQAAVSMQLRRLEDELGQRLLDRSPRGVQLTEAGHLLLPYAH
AILGAGADARRALSAGQVSGTVRLGMLEDIAVGRLPRALRRFSIAYPQVALEIVVDSSVALSNRLADSSLDVVVGDPALV
DAAPLLTWRQPLFWVGARGFGREVEAPLPVVAFGGACLWQQQVLAALRRAGIAWRIVCTSTSLPAVQSAVEAGLGVSVLL
DGNIRSESMRVLGQADGLPDAPTADFGLFTREVPGAQAAAVQTLQTFLCEELHLGLREGEPSLMPVSSASG

Sequences:

>Translated_311_residues
MPTSRTLMSRDLDSSLLRTFVTVAETGAMGVAATRLARTQAAVSMQLRRLEDELGQRLLDRSPRGVQLTEAGHLLLPYAH
AILGAGADARRALSAGQVSGTVRLGMLEDIAVGRLPRALRRFSIAYPQVALEIVVDSSVALSNRLADSSLDVVVGDPALV
DAAPLLTWRQPLFWVGARGFGREVEAPLPVVAFGGACLWQQQVLAALRRAGIAWRIVCTSTSLPAVQSAVEAGLGVSVLL
DGNIRSESMRVLGQADGLPDAPTADFGLFTREVPGAQAAAVQTLQTFLCEELHLGLREGEPSLMPVSSASG
>Mature_310_residues
PTSRTLMSRDLDSSLLRTFVTVAETGAMGVAATRLARTQAAVSMQLRRLEDELGQRLLDRSPRGVQLTEAGHLLLPYAHA
ILGAGADARRALSAGQVSGTVRLGMLEDIAVGRLPRALRRFSIAYPQVALEIVVDSSVALSNRLADSSLDVVVGDPALVD
AAPLLTWRQPLFWVGARGFGREVEAPLPVVAFGGACLWQQQVLAALRRAGIAWRIVCTSTSLPAVQSAVEAGLGVSVLLD
GNIRSESMRVLGQADGLPDAPTADFGLFTREVPGAQAAAVQTLQTFLCEELHLGLREGEPSLMPVSSASG

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=267, Percent_Identity=35.5805243445693, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787806, Length=236, Percent_Identity=25.8474576271186, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788748, Length=236, Percent_Identity=31.3559322033898, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=32.1678321678322, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994962, Length=150, Percent_Identity=30, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=30.0813008130081, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87081904, Length=162, Percent_Identity=32.7160493827161, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787530, Length=240, Percent_Identity=25.8333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787589, Length=126, Percent_Identity=39.6825396825397, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788296, Length=222, Percent_Identity=25.6756756756757, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI157672245, Length=228, Percent_Identity=28.0701754385965, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32866; Mature: 32735

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSRTLMSRDLDSSLLRTFVTVAETGAMGVAATRLARTQAAVSMQLRRLEDELGQRLLD
CCCCHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RSPRGVQLTEAGHLLLPYAHAILGAGADARRALSAGQVSGTVRLGMLEDIAVGRLPRALR
CCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHH
RFSIAYPQVALEIVVDSSVALSNRLADSSLDVVVGDPALVDAAPLLTWRQPLFWVGARGF
HHHHCCHHEEEEEEECCCHHHHHHCCCCCCCEEECCCHHHCCHHHHHHCCCCEEECCCCC
GREVEAPLPVVAFGGACLWQQQVLAALRRAGIAWRIVCTSTSLPAVQSAVEAGLGVSVLL
CCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCEEEEE
DGNIRSESMRVLGQADGLPDAPTADFGLFTREVPGAQAAAVQTLQTFLCEELHLGLREGE
CCCCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PSLMPVSSASG
CCEECCCCCCC
>Mature Secondary Structure 
PTSRTLMSRDLDSSLLRTFVTVAETGAMGVAATRLARTQAAVSMQLRRLEDELGQRLLD
CCCHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RSPRGVQLTEAGHLLLPYAHAILGAGADARRALSAGQVSGTVRLGMLEDIAVGRLPRALR
CCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHH
RFSIAYPQVALEIVVDSSVALSNRLADSSLDVVVGDPALVDAAPLLTWRQPLFWVGARGF
HHHHCCHHEEEEEEECCCHHHHHHCCCCCCCEEECCCHHHCCHHHHHHCCCCEEECCCCC
GREVEAPLPVVAFGGACLWQQQVLAALRRAGIAWRIVCTSTSLPAVQSAVEAGLGVSVLL
CCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCEEEEE
DGNIRSESMRVLGQADGLPDAPTADFGLFTREVPGAQAAAVQTLQTFLCEELHLGLREGE
CCCCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PSLMPVSSASG
CCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]