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The map label for this gene is pgl [H]

Identifier: 91782378

GI number: 91782378

Start: 1115744

End: 1116451

Strand: Reverse

Name: pgl [H]

Synonym: Bxe_A3453

Alternate gene names: 91782378

Gene position: 1116451-1115744 (Counterclockwise)

Preceding gene: 91782379

Following gene: 91782377

Centisome position: 22.8

GC content: 64.12

Gene sequence:

>708_bases
GTGATCGAGCTTCACGCTTTCGACGATCAACGCGCCCAGTCTGACGCGTTGGCGAAAGCGGTTGGCGACGCGCTACATGC
GTCGCTCGCCGCACAGGCCGCCGGTGCCGCCACCGGCGCGCGCCAGGCAATGCTTGCAGTGTCCGGCGGCAGCAGTCCAC
GGCCGTTCCTGCAGACCTTGTCCACGCAGTCCTTCGACTGGCCACGGATCGCCGTGACGCTGGTCGACGACCGCTGGGTG
CCCGAAACGGACAGCGCGAGCAATTCGCAGCTGGTGCACGCCACGCTGTTGCAGAACGCCGCGAAAGACACCGCGTTCTG
GCCGCTCGTGGACACCACGCAGGATCTCGACGCGCATGTCGCCGCGCTGAACGCCGACGCGCGTTTCAGCAGCGTGCCCG
ACGTCGCGATTCTCGGCATGGGCGAAGACGGCCACACCGCGTCGATCTTTGCCGACTCGCCCGAATGGGACCATGCGATC
ACCACCACCGAGCGCTTCGTTGCCGTGCATCCCGGCAGCGCGCCGCATGCGCGCGTGAGCTGGTCGCTATCCGCGTTGAA
GGATGTGAAGCACCTGTTTTTGCTGATTGCGGGACCGCGCAAGATGGACGTGCTGAATGCCGCGTCCGCTTCGCTACAAA
AAAATGCCATCTCACAGTTGGCAAACGACAAGGGAGTGAGACTCGATGTCTACTGGTGTGCAAACTAA

Upstream 100 bases:

>100_bases
GTATCACGAGGGCGCCTGCAAGTCATCCACCTTGCAGGCATCGCGTGAGAGCAGTACGGCACATTCCGCAGATCCAACAA
GAAAGCAGCACGGAGGAGAA

Downstream 100 bases:

>100_bases
GGCTGCTCCGGGCGCGGGCCAGCACGCCGATGGACCCAGGCTGCTGGCCGATATCGGCGGCACCAACGCGCGCTTCGCGC
TGGAGACGAGTCCGGGCGAA

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MIELHAFDDQRAQSDALAKAVGDALHASLAAQAAGAATGARQAMLAVSGGSSPRPFLQTLSTQSFDWPRIAVTLVDDRWV
PETDSASNSQLVHATLLQNAAKDTAFWPLVDTTQDLDAHVAALNADARFSSVPDVAILGMGEDGHTASIFADSPEWDHAI
TTTERFVAVHPGSAPHARVSWSLSALKDVKHLFLLIAGPRKMDVLNAASASLQKNAISQLANDKGVRLDVYWCAN

Sequences:

>Translated_235_residues
MIELHAFDDQRAQSDALAKAVGDALHASLAAQAAGAATGARQAMLAVSGGSSPRPFLQTLSTQSFDWPRIAVTLVDDRWV
PETDSASNSQLVHATLLQNAAKDTAFWPLVDTTQDLDAHVAALNADARFSSVPDVAILGMGEDGHTASIFADSPEWDHAI
TTTERFVAVHPGSAPHARVSWSLSALKDVKHLFLLIAGPRKMDVLNAASASLQKNAISQLANDKGVRLDVYWCAN
>Mature_235_residues
MIELHAFDDQRAQSDALAKAVGDALHASLAAQAAGAATGARQAMLAVSGGSSPRPFLQTLSTQSFDWPRIAVTLVDDRWV
PETDSASNSQLVHATLLQNAAKDTAFWPLVDTTQDLDAHVAALNADARFSSVPDVAILGMGEDGHTASIFADSPEWDHAI
TTTERFVAVHPGSAPHARVSWSLSALKDVKHLFLLIAGPRKMDVLNAASASLQKNAISQLANDKGVRLDVYWCAN

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=196, Percent_Identity=34.1836734693878, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115533058, Length=197, Percent_Identity=29.4416243654822, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533060, Length=197, Percent_Identity=29.4416243654822, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24988; Mature: 24988

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELHAFDDQRAQSDALAKAVGDALHASLAAQAAGAATGARQAMLAVSGGSSPRPFLQTL
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHH
STQSFDWPRIAVTLVDDRWVPETDSASNSQLVHATLLQNAAKDTAFWPLVDTTQDLDAHV
CCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEECCCCCCCCCCCEE
AALNADARFSSVPDVAILGMGEDGHTASIFADSPEWDHAITTTERFVAVHPGSAPHARVS
EEECCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCEEECCEEEEEECCCCCCCCEEE
WSLSALKDVKHLFLLIAGPRKMDVLNAASASLQKNAISQLANDKGVRLDVYWCAN
EHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MIELHAFDDQRAQSDALAKAVGDALHASLAAQAAGAATGARQAMLAVSGGSSPRPFLQTL
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHH
STQSFDWPRIAVTLVDDRWVPETDSASNSQLVHATLLQNAAKDTAFWPLVDTTQDLDAHV
CCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEECCCCCCCCCCCEE
AALNADARFSSVPDVAILGMGEDGHTASIFADSPEWDHAITTTERFVAVHPGSAPHARVS
EEECCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCEEECCEEEEEECCCCCCCCEEE
WSLSALKDVKHLFLLIAGPRKMDVLNAASASLQKNAISQLANDKGVRLDVYWCAN
EHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA