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The map label for this gene is mhpF [C]

Identifier: 91782287

GI number: 91782287

Start: 1013664

End: 1014608

Strand: Direct

Name: mhpF [C]

Synonym: Bxe_A3547

Alternate gene names: 91782287

Gene position: 1013664-1014608 (Clockwise)

Preceding gene: 91782286

Following gene: 91782288

Centisome position: 20.7

GC content: 61.69

Gene sequence:

>945_bases
ATGAGTTCCAATGACGAAAAGCACGCGGTTGCCATCATCGGCTCGGGAAACATCGGCACCGACCTGATGGTGAAGATCCT
GCGGCACGGAAAACACCTGAAGATGGGCGCATTCGTCGGCATCGATCCTGAATCGGACGGCCTGAAGCGGGCCGAACGCA
TGGGCGTGCCGACCGTGACAACCGGAATCGATGGCCTGCTGGCTCATCCGGATTTCGGATCCATCCGCTATGTATTCGAT
GCAACGAGCGCGGGCGCCCATGCCCGGCATGAGCAGTTGCTGCGCCCGCACGGGGTGCGGGTGATTGACCTCACGCCGGC
GGCGATCGGTCCTTTTGTCGTTCCGGCAGTCAACATCGACCAGCATCTCGATTCGCCGAACGTCAACATGGTGACCTGCG
GCGGACAGGCGACGATTCCGATGGTTGCAGCTGTTTCACGCGTCGTGCCGGTCGAGTATGCCGAGATTGTTGCGTCGATC
TCGAGCCGTTCCGCTGGGCCGGGCACGCGTGCAAACATCGACGAGTTCACGGAAACAACATCGAACGCGATCGTACAGGT
CGGTGGCGCGAAAGCAGGCAAGGCGATCATCGTTCTCAATCCGGCAGAGCCACCGCTGATCATGCGCGACACGGTCTACT
GCTTGGTTCCCGGAGATGCGAGCCAGTCTGCAATCGTCGAGTCGGTCGAGCAGATGGTCGACTCCGTTCGCACCTACGTA
CCGGGATATCGCCTCAAGCAGGCTGTGCAGTTCGACGAGTTCAAGGGACGCATGCCCCAGGAGCTGGCCACGGTAAGGGC
GCCTCGCCTGAAAGTGTCGGTATTCCTCGAGGTTGAGGGCGCGGGGCATTACCTGCCGAGCTATGCGGGGAACCTGGACA
TCATGACCAGCGCCGCGCTGGCTACGGCCGAGCGCATCGCGGCACGTCAGCCGGTGACGGCTTAA

Upstream 100 bases:

>100_bases
CTCGGCCCGATGGTTGCCGTGCAGGCCAGCCAGACCTACGTCGCTCACATTGACGGGTTTGCCCCTGTACGGGCGATTTT
CTCCTGATGAGGTAATGCAC

Downstream 100 bases:

>100_bases
GGAGGGAGTGGACCATGAATGAGAAGAGCAGGAAAATTTATGTCTCGGACGTGACCCTGCGTGATGGCATGCACGCCATC
CGGCATCAGTACAGTCTGGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] 1

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSSNDEKHAVAIIGSGNIGTDLMVKILRHGKHLKMGAFVGIDPESDGLKRAERMGVPTVTTGIDGLLAHPDFGSIRYVFD
ATSAGAHARHEQLLRPHGVRVIDLTPAAIGPFVVPAVNIDQHLDSPNVNMVTCGGQATIPMVAAVSRVVPVEYAEIVASI
SSRSAGPGTRANIDEFTETTSNAIVQVGGAKAGKAIIVLNPAEPPLIMRDTVYCLVPGDASQSAIVESVEQMVDSVRTYV
PGYRLKQAVQFDEFKGRMPQELATVRAPRLKVSVFLEVEGAGHYLPSYAGNLDIMTSAALATAERIAARQPVTA

Sequences:

>Translated_314_residues
MSSNDEKHAVAIIGSGNIGTDLMVKILRHGKHLKMGAFVGIDPESDGLKRAERMGVPTVTTGIDGLLAHPDFGSIRYVFD
ATSAGAHARHEQLLRPHGVRVIDLTPAAIGPFVVPAVNIDQHLDSPNVNMVTCGGQATIPMVAAVSRVVPVEYAEIVASI
SSRSAGPGTRANIDEFTETTSNAIVQVGGAKAGKAIIVLNPAEPPLIMRDTVYCLVPGDASQSAIVESVEQMVDSVRTYV
PGYRLKQAVQFDEFKGRMPQELATVRAPRLKVSVFLEVEGAGHYLPSYAGNLDIMTSAALATAERIAARQPVTA
>Mature_313_residues
SSNDEKHAVAIIGSGNIGTDLMVKILRHGKHLKMGAFVGIDPESDGLKRAERMGVPTVTTGIDGLLAHPDFGSIRYVFDA
TSAGAHARHEQLLRPHGVRVIDLTPAAIGPFVVPAVNIDQHLDSPNVNMVTCGGQATIPMVAAVSRVVPVEYAEIVASIS
SRSAGPGTRANIDEFTETTSNAIVQVGGAKAGKAIIVLNPAEPPLIMRDTVYCLVPGDASQSAIVESVEQMVDSVRTYVP
GYRLKQAVQFDEFKGRMPQELATVRAPRLKVSVFLEVEGAGHYLPSYAGNLDIMTSAALATAERIAARQPVTA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=304, Percent_Identity=66.4473684210526, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH1_BURXL (Q143P8)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_557493.1
- ProteinModelPortal:   Q143P8
- SMR:   Q143P8
- GeneID:   4004910
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A3547
- HOGENOM:   HBG300125
- OMA:   MIKVIRH
- ProtClustDB:   PRK08300
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 33254; Mature: 33122

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: BINDING 291-291

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNDEKHAVAIIGSGNIGTDLMVKILRHGKHLKMGAFVGIDPESDGLKRAERMGVPTVT
CCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEECEEEECCCCCHHHHHHHHCCCCEEE
TGIDGLLAHPDFGSIRYVFDATSAGAHARHEQLLRPHGVRVIDLTPAAIGPFVVPAVNID
CCCCCEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCHH
QHLDSPNVNMVTCGGQATIPMVAAVSRVVPVEYAEIVASISSRSAGPGTRANIDEFTETT
HHCCCCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SNAIVQVGGAKAGKAIIVLNPAEPPLIMRDTVYCLVPGDASQSAIVESVEQMVDSVRTYV
CCEEEEECCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
PGYRLKQAVQFDEFKGRMPQELATVRAPRLKVSVFLEVEGAGHYLPSYAGNLDIMTSAAL
CCHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCEEHHHHHHH
ATAERIAARQPVTA
HHHHHHHCCCCCCC
>Mature Secondary Structure 
SSNDEKHAVAIIGSGNIGTDLMVKILRHGKHLKMGAFVGIDPESDGLKRAERMGVPTVT
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEECEEEECCCCCHHHHHHHHCCCCEEE
TGIDGLLAHPDFGSIRYVFDATSAGAHARHEQLLRPHGVRVIDLTPAAIGPFVVPAVNID
CCCCCEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCHH
QHLDSPNVNMVTCGGQATIPMVAAVSRVVPVEYAEIVASISSRSAGPGTRANIDEFTETT
HHCCCCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SNAIVQVGGAKAGKAIIVLNPAEPPLIMRDTVYCLVPGDASQSAIVESVEQMVDSVRTYV
CCEEEEECCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
PGYRLKQAVQFDEFKGRMPQELATVRAPRLKVSVFLEVEGAGHYLPSYAGNLDIMTSAAL
CCHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCEEHHHHHHH
ATAERIAARQPVTA
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA