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The map label for this gene is gpsA

Identifier: 91781669

GI number: 91781669

Start: 320010

End: 321017

Strand: Direct

Name: gpsA

Synonym: Bxe_A4177

Alternate gene names: 91781669

Gene position: 320010-321017 (Clockwise)

Preceding gene: 91781668

Following gene: 91781670

Centisome position: 6.54

GC content: 67.66

Gene sequence:

>1008_bases
GTGCCGGCTATGAAGGTTGCCGTCCTCGGCGCCGGCGCATGGGGCACCGCGCTCGCCGGCCATCTGGCCGTACGGCACGA
CACAGTGTTGTGGGCGCGCCAGCCCGCGCTCATTGCCGATCTCCGCGCTTCACACGAAAACGCCCGCTATCTGGCGGGCG
TTGCGTTGCCGCCGGCGCTTCGCTATGAAACGGATCTGAACGCAGCGCTCGACCACGCGCTCGCCGACAACGCGTTATGC
GTCGTGGCAACCCCCGTGGCCGGACTGCGCGGTCTGTTCCGGGCCATGCGCGATGCAGGCAAAGTGCCGGCGCATGTGGT
GTGGCTGTGCAAAGGTTTTGAAGCCGACTCGCAGTTGATGCCACATCAGGTGGTCGCGGCCGAACTGCCGGAGCACGGCA
GCAACGGCGTGCTGTCGGGTCCGAGTTTTGCGCGTGAAGTCGGGCAGGGCTTGCCGGTCGCGTTGACCATCGCCAGCGCT
TCGGCGGCGTGCCGCGAGCGCACGGTGGCCGCGTTCCATCACGGCGCCATGCGCATCTATACCGGCGACGACGTCGTCGG
CGTGGAAGTGGGCGGCGCGGTGAAAAACGTGCTTGCCATTGCCACGGGCATTGCCGATGGACTCGGGCTCGGTCTGAACG
CGCGTGCGGCATTGATCACGCGCGGCCTCGCTGAAATGTCGCGCCTCGGCGTGACGCTCGGCGGCCGTGCGGAAACCTTC
ACCGGTTTGACCGGCCTGGGCGATCTGATCCTGACCGCCACCGGCGATCTGTCGCGCAATCGCACGGTCGGCCTGCAACT
CGCTGCGGGCCGCACGCTCGACGATATTCTCGGCGGCCTCGGTCACGTGGCCGAAGGCGTGCGTTGCGCGCAAGCGGTTC
TTGCGATCGCCCGCGCACATGCAATCGAGATGCCTATCACGCAGGCGGTGTGTGCCGTTCTGTTCGACGGCGTGGCTCCG
CGCGACGCCGTCAGCGCCCTGCTGCGGCGCGACTCCAAAGCCGAATAA

Upstream 100 bases:

>100_bases
GAGATCAACTTCCAGGCACTGTACGAGCAACGCCTCGCGCAGATGGGCGGCCAGGACGGCGCGGCGCAAAACGGCGTCAC
GCACTAAGGTGTCGCGAGCA

Downstream 100 bases:

>100_bases
GCCTTGTCTATCAGCCGTTTGGCGCGCAAAAGCGCTGAACGACTGCCCGCTATCGCTGTCCACGTTTTTATCGACGCTAC
GGATCAGCGAGGTTCCCATG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPAMKVAVLGAGAWGTALAGHLAVRHDTVLWARQPALIADLRASHENARYLAGVALPPALRYETDLNAALDHALADNALC
VVATPVAGLRGLFRAMRDAGKVPAHVVWLCKGFEADSQLMPHQVVAAELPEHGSNGVLSGPSFAREVGQGLPVALTIASA
SAACRERTVAAFHHGAMRIYTGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALITRGLAEMSRLGVTLGGRAETF
TGLTGLGDLILTATGDLSRNRTVGLQLAAGRTLDDILGGLGHVAEGVRCAQAVLAIARAHAIEMPITQAVCAVLFDGVAP
RDAVSALLRRDSKAE

Sequences:

>Translated_335_residues
MPAMKVAVLGAGAWGTALAGHLAVRHDTVLWARQPALIADLRASHENARYLAGVALPPALRYETDLNAALDHALADNALC
VVATPVAGLRGLFRAMRDAGKVPAHVVWLCKGFEADSQLMPHQVVAAELPEHGSNGVLSGPSFAREVGQGLPVALTIASA
SAACRERTVAAFHHGAMRIYTGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALITRGLAEMSRLGVTLGGRAETF
TGLTGLGDLILTATGDLSRNRTVGLQLAAGRTLDDILGGLGHVAEGVRCAQAVLAIARAHAIEMPITQAVCAVLFDGVAP
RDAVSALLRRDSKAE
>Mature_334_residues
PAMKVAVLGAGAWGTALAGHLAVRHDTVLWARQPALIADLRASHENARYLAGVALPPALRYETDLNAALDHALADNALCV
VATPVAGLRGLFRAMRDAGKVPAHVVWLCKGFEADSQLMPHQVVAAELPEHGSNGVLSGPSFAREVGQGLPVALTIASAS
AACRERTVAAFHHGAMRIYTGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALITRGLAEMSRLGVTLGGRAETFT
GLTGLGDLILTATGDLSRNRTVGLQLAAGRTLDDILGGLGHVAEGVRCAQAVLAIARAHAIEMPITQAVCAVLFDGVAPR
DAVSALLRRDSKAE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=340, Percent_Identity=27.6470588235294, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI24307999, Length=349, Percent_Identity=26.647564469914, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1790037, Length=332, Percent_Identity=42.1686746987952, Blast_Score=231, Evalue=7e-62,
Organism=Caenorhabditis elegans, GI17507425, Length=338, Percent_Identity=27.5147928994083, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32564403, Length=366, Percent_Identity=26.775956284153, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI32564399, Length=358, Percent_Identity=26.8156424581006, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193210136, Length=366, Percent_Identity=26.775956284153, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193210134, Length=354, Percent_Identity=23.728813559322, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320181, Length=354, Percent_Identity=27.4011299435028, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324513, Length=359, Percent_Identity=27.0194986072423, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281362270, Length=303, Percent_Identity=27.7227722772277, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45551945, Length=303, Percent_Identity=27.7227722772277, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17136204, Length=349, Percent_Identity=26.3610315186246, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17136200, Length=349, Percent_Identity=26.3610315186246, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17136202, Length=349, Percent_Identity=26.3610315186246, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI22026922, Length=289, Percent_Identity=24.2214532871972, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24648969, Length=271, Percent_Identity=28.4132841328413, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_BURXL (Q146B6)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_556875.1
- ProteinModelPortal:   Q146B6
- SMR:   Q146B6
- GeneID:   4001861
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A4177
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 34413; Mature: 34282

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 195-195 BINDING 111-111 BINDING 111-111 BINDING 144-144 BINDING 259-259 BINDING 285-285

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAMKVAVLGAGAWGTALAGHLAVRHDTVLWARQPALIADLRASHENARYLAGVALPPAL
CCCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCC
RYETDLNAALDHALADNALCVVATPVAGLRGLFRAMRDAGKVPAHVVWLCKGFEADSQLM
CCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCC
PHQVVAAELPEHGSNGVLSGPSFAREVGQGLPVALTIASASAACRERTVAAFHHGAMRIY
CHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEEE
TGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALITRGLAEMSRLGVTLGGRAETF
ECCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHH
TGLTGLGDLILTATGDLSRNRTVGLQLAAGRTLDDILGGLGHVAEGVRCAQAVLAIARAH
CCHHCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIEMPITQAVCAVLFDGVAPRDAVSALLRRDSKAE
HHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PAMKVAVLGAGAWGTALAGHLAVRHDTVLWARQPALIADLRASHENARYLAGVALPPAL
CCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCC
RYETDLNAALDHALADNALCVVATPVAGLRGLFRAMRDAGKVPAHVVWLCKGFEADSQLM
CCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCC
PHQVVAAELPEHGSNGVLSGPSFAREVGQGLPVALTIASASAACRERTVAAFHHGAMRIY
CHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEEE
TGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALITRGLAEMSRLGVTLGGRAETF
ECCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHH
TGLTGLGDLILTATGDLSRNRTVGLQLAAGRTLDDILGGLGHVAEGVRCAQAVLAIARAH
CCHHCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIEMPITQAVCAVLFDGVAPRDAVSALLRRDSKAE
HHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA