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The map label for this gene is dctB [H]

Identifier: 91781650

GI number: 91781650

Start: 299563

End: 301563

Strand: Direct

Name: dctB [H]

Synonym: Bxe_A4196

Alternate gene names: 91781650

Gene position: 299563-301563 (Clockwise)

Preceding gene: 91781649

Following gene: 91781651

Centisome position: 6.12

GC content: 65.57

Gene sequence:

>2001_bases
ATGAAACCGGTGTCCGCGCGCCGAACCTCCGTGCCGTCGGCCGACGAAGCTTGCGCCGACGGCACGTCGCCTTATGCCAC
AATAAACGATCCTCACCGATCGGATATTGCCAACGTGACGCGCCGCCTGCTGATCCTCTTCGCGCTCGTCGCCGGGCTCG
TGGCAGCGTGCGGGCTCACGTACAGCATCGCGTGGCAAAGCGGCATCGACCATTTGCGGCGCAACGCCGCGGTGCGAGTC
GACCGTACCACGAGCGCGCTGAAGAGCACGCTCGAACGCTACGAATCGCTGCCTTATCTGCTGGCGGAACACCCTATCGT
GCAGGACGTGCTGGTCGATCCCAGTGCGGCCAATGTCGCGCGCGCCAATCTTTATCTCGAAGACCTGAACCGCCACGCGC
GCGCCACCGTCACGTACATCATTCCGCTCGACGGCTTTTGCGTTGCGGCGAGCAACTGGCGCGGGCCGGGCAGCTTCATC
GGTGCCGGCTACCAGTTCCGGCCGTATTTTCTCGACGCGGTCAAAGGCGGCGTGGGCCGCTTCTTCGGCATTGGTACGAT
TTCGCAGGCGCCGGGCTACTACATCTCGCAGCCGGTGCGGCGCGACGGCAGGATTGTCGGCGTGGCGGTCGTCAAACTCG
ATCTCGAATGGTTTCAGGGCGCGGATGCGTCCGAGCCGCTCGTCGTGACCGACGACCACGGCGTGATTTTTCTGTCGTCG
ATACCGGCGTGGAAATACCACACGATCCGGCCGCTGTCGGGGCCGGTCGCCGATTCCATCTACCAGGCGCGTCAATACGC
GCAGCAGCCGATTCCGCCGCTGCCGGTGTCGATCGAACGCACGCTCGAAGGCAACGCGCAGATCGTGCGCATTGGCGGCG
GCCGCTATGCGCCACGCTATCTCGCGTCGCGGCGCGGCATGGGTGAGCCGGACTGGCATCTGATCACCATGTCGCCCGTC
GATCCGGTCGACGCCGACGCGCGCAAGGCGACCATCGTCACCGGGTTCGGCTACGTATCGCTGGTGTTGCTCGCGTTCTA
CTGGAGAATGCGCCGTGCTCGCGTACGCGAAGTAATGCGCAGCCGCGCGCTGCTGCAAAAGGCGTACGCCGAACTGAACC
GGCGCGTCGCCGAGCGCACCGCGGATCTCTCGCAGGCGAACGAACAGTTGCAGAAAGAAGTGGCCGAACGCACGCGCGCC
GAACAGGAGTTGCGCGCCGCGCATGATGAACTGATCCAGGCGAGCAAGCTCGCCGCGCTCGGTCAGATGGCGGCCGGCAT
TACGCATGAACTGAATCAGCCGCTCGCCGCGTTGCGCGGTTTCTCGGACAACACACGCGTGCTGCTCGAACGCGGCGACC
AGGTGTCGGCGCGCGAAAATCTCGAAGCGATCGCGGCGCTCACTGAGCGCATGGGCAAGATCACCAATCAGCTGAAACTG
TTCGTCGGGCGGGCGCGGCCGCGCAGTGCGCGTGCGCCGATCGTGCGGGCGTTGCGTAACGTCGTCGCGCTGCTGCAAAA
GCGCTTGCAGGGCGTCGAGGTCGAACTCGTCCTGTTCGATGCGCAAAGCGGCACGCGTGCGCCGCTGAGTCTCGCCGACG
ACCATCCCGAACTGGTCGCGCATTGCGACGATCTGCGCCTCGAACAGGTGCTGATCAACCTGCTCGGCAACGCGCTCGAT
GCGACTGCCGACATCAACTCGCCGCGCATTTCGATCGAGATCGAAGTCGCCGACGCGAACCTGTCGTTCGCCGTCAGCGA
CAACGGCCCCGGTATTGCCGACGACGTCCTGCCGCGCCTGTTCGAGCCGTTCTTCACCACCAAGGAAATGGGCCAGGGGC
TGGGACTCGGGCTGGCGATATCGTCTTCGATCGCGCGCGATTGCGGCGGCTCGCTCGTGGCGCGCAACGCGCCGGGCGGC
GGTGCATTATTCGTGTTGACGCTGCGCCGCGCGCGCGTGCAGACGAGCCACACACCGGACCCGCTGACAACGGGCTCCTG
A

Upstream 100 bases:

>100_bases
GCCTTGCGCGGCGACGTGGCGATCAAAGAGCCGGCCGGCGTTTAAACGGCGCATCGGCAACCCGCTCCAGCGCAACCCCG
ACGGCCGCGGATACCAGCGT

Downstream 100 bases:

>100_bases
ATCACACGGAAAACGCCATGCTGAATCACGGCCTGCAAGTGCTGTATATCGAAGACGACGAACTGGTGCGGCGCGCCAGC
GTGCAGAGTCTGCAACTGGC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MKPVSARRTSVPSADEACADGTSPYATINDPHRSDIANVTRRLLILFALVAGLVAACGLTYSIAWQSGIDHLRRNAAVRV
DRTTSALKSTLERYESLPYLLAEHPIVQDVLVDPSAANVARANLYLEDLNRHARATVTYIIPLDGFCVAASNWRGPGSFI
GAGYQFRPYFLDAVKGGVGRFFGIGTISQAPGYYISQPVRRDGRIVGVAVVKLDLEWFQGADASEPLVVTDDHGVIFLSS
IPAWKYHTIRPLSGPVADSIYQARQYAQQPIPPLPVSIERTLEGNAQIVRIGGGRYAPRYLASRRGMGEPDWHLITMSPV
DPVDADARKATIVTGFGYVSLVLLAFYWRMRRARVREVMRSRALLQKAYAELNRRVAERTADLSQANEQLQKEVAERTRA
EQELRAAHDELIQASKLAALGQMAAGITHELNQPLAALRGFSDNTRVLLERGDQVSARENLEAIAALTERMGKITNQLKL
FVGRARPRSARAPIVRALRNVVALLQKRLQGVEVELVLFDAQSGTRAPLSLADDHPELVAHCDDLRLEQVLINLLGNALD
ATADINSPRISIEIEVADANLSFAVSDNGPGIADDVLPRLFEPFFTTKEMGQGLGLGLAISSSIARDCGGSLVARNAPGG
GALFVLTLRRARVQTSHTPDPLTTGS

Sequences:

>Translated_666_residues
MKPVSARRTSVPSADEACADGTSPYATINDPHRSDIANVTRRLLILFALVAGLVAACGLTYSIAWQSGIDHLRRNAAVRV
DRTTSALKSTLERYESLPYLLAEHPIVQDVLVDPSAANVARANLYLEDLNRHARATVTYIIPLDGFCVAASNWRGPGSFI
GAGYQFRPYFLDAVKGGVGRFFGIGTISQAPGYYISQPVRRDGRIVGVAVVKLDLEWFQGADASEPLVVTDDHGVIFLSS
IPAWKYHTIRPLSGPVADSIYQARQYAQQPIPPLPVSIERTLEGNAQIVRIGGGRYAPRYLASRRGMGEPDWHLITMSPV
DPVDADARKATIVTGFGYVSLVLLAFYWRMRRARVREVMRSRALLQKAYAELNRRVAERTADLSQANEQLQKEVAERTRA
EQELRAAHDELIQASKLAALGQMAAGITHELNQPLAALRGFSDNTRVLLERGDQVSARENLEAIAALTERMGKITNQLKL
FVGRARPRSARAPIVRALRNVVALLQKRLQGVEVELVLFDAQSGTRAPLSLADDHPELVAHCDDLRLEQVLINLLGNALD
ATADINSPRISIEIEVADANLSFAVSDNGPGIADDVLPRLFEPFFTTKEMGQGLGLGLAISSSIARDCGGSLVARNAPGG
GALFVLTLRRARVQTSHTPDPLTTGS
>Mature_666_residues
MKPVSARRTSVPSADEACADGTSPYATINDPHRSDIANVTRRLLILFALVAGLVAACGLTYSIAWQSGIDHLRRNAAVRV
DRTTSALKSTLERYESLPYLLAEHPIVQDVLVDPSAANVARANLYLEDLNRHARATVTYIIPLDGFCVAASNWRGPGSFI
GAGYQFRPYFLDAVKGGVGRFFGIGTISQAPGYYISQPVRRDGRIVGVAVVKLDLEWFQGADASEPLVVTDDHGVIFLSS
IPAWKYHTIRPLSGPVADSIYQARQYAQQPIPPLPVSIERTLEGNAQIVRIGGGRYAPRYLASRRGMGEPDWHLITMSPV
DPVDADARKATIVTGFGYVSLVLLAFYWRMRRARVREVMRSRALLQKAYAELNRRVAERTADLSQANEQLQKEVAERTRA
EQELRAAHDELIQASKLAALGQMAAGITHELNQPLAALRGFSDNTRVLLERGDQVSARENLEAIAALTERMGKITNQLKL
FVGRARPRSARAPIVRALRNVVALLQKRLQGVEVELVLFDAQSGTRAPLSLADDHPELVAHCDDLRLEQVLINLLGNALD
ATADINSPRISIEIEVADANLSFAVSDNGPGIADDVLPRLFEPFFTTKEMGQGLGLGLAISSSIARDCGGSLVARNAPGG
GALFVLTLRRARVQTSHTPDPLTTGS

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=32.2448979591837, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=29.7619047619048, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790861, Length=233, Percent_Identity=32.618025751073, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=287, Percent_Identity=29.616724738676, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789149, Length=290, Percent_Identity=26.8965517241379, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=264, Percent_Identity=26.5151515151515, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=286, Percent_Identity=29.3706293706294, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788393, Length=258, Percent_Identity=29.8449612403101, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=27.8195488721804, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72549; Mature: 72549

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVSARRTSVPSADEACADGTSPYATINDPHRSDIANVTRRLLILFALVAGLVAACGLT
CCCCCCCCCCCCCCHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YSIAWQSGIDHLRRNAAVRVDRTTSALKSTLERYESLPYLLAEHPIVQDVLVDPSAANVA
EEEHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHCCCCHHHHH
RANLYLEDLNRHARATVTYIIPLDGFCVAASNWRGPGSFIGAGYQFRPYFLDAVKGGVGR
HHHHHHHHHCCCCEEEEEEEEECCCEEEEECCCCCCCCCCCCCCEECHHHHHHHHCCHHH
FFGIGTISQAPGYYISQPVRRDGRIVGVAVVKLDLEWFQGADASEPLVVTDDHGVIFLSS
HEECCCCCCCCCCHHCCCCCCCCCEEEEEEEEEEHHHHCCCCCCCCEEEECCCCEEEEEC
IPAWKYHTIRPLSGPVADSIYQARQYAQQPIPPLPVSIERTLEGNAQIVRIGGGRYAPRY
CCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEECCCCCCHHH
LASRRGMGEPDWHLITMSPVDPVDADARKATIVTGFGYVSLVLLAFYWRMRRARVREVMR
HHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
SRALLQKAYAELNRRVAERTADLSQANEQLQKEVAERTRAEQELRAAHDELIQASKLAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQMAAGITHELNQPLAALRGFSDNTRVLLERGDQVSARENLEAIAALTERMGKITNQLKL
HHHHHHHHHHHCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVGRARPRSARAPIVRALRNVVALLQKRLQGVEVELVLFDAQSGTRAPLSLADDHPELVA
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHH
HCDDLRLEQVLINLLGNALDATADINSPRISIEIEVADANLSFAVSDNGPGIADDVLPRL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCEEEEECCCCCCCHHHHHHHH
FEPFFTTKEMGQGLGLGLAISSSIARDCGGSLVARNAPGGGALFVLTLRRARVQTSHTPD
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEHHHHHHCCCCCCC
PLTTGS
CCCCCC
>Mature Secondary Structure
MKPVSARRTSVPSADEACADGTSPYATINDPHRSDIANVTRRLLILFALVAGLVAACGLT
CCCCCCCCCCCCCCHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YSIAWQSGIDHLRRNAAVRVDRTTSALKSTLERYESLPYLLAEHPIVQDVLVDPSAANVA
EEEHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHCCCCHHHHH
RANLYLEDLNRHARATVTYIIPLDGFCVAASNWRGPGSFIGAGYQFRPYFLDAVKGGVGR
HHHHHHHHHCCCCEEEEEEEEECCCEEEEECCCCCCCCCCCCCCEECHHHHHHHHCCHHH
FFGIGTISQAPGYYISQPVRRDGRIVGVAVVKLDLEWFQGADASEPLVVTDDHGVIFLSS
HEECCCCCCCCCCHHCCCCCCCCCEEEEEEEEEEHHHHCCCCCCCCEEEECCCCEEEEEC
IPAWKYHTIRPLSGPVADSIYQARQYAQQPIPPLPVSIERTLEGNAQIVRIGGGRYAPRY
CCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEECCCCCCHHH
LASRRGMGEPDWHLITMSPVDPVDADARKATIVTGFGYVSLVLLAFYWRMRRARVREVMR
HHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
SRALLQKAYAELNRRVAERTADLSQANEQLQKEVAERTRAEQELRAAHDELIQASKLAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQMAAGITHELNQPLAALRGFSDNTRVLLERGDQVSARENLEAIAALTERMGKITNQLKL
HHHHHHHHHHHCCHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVGRARPRSARAPIVRALRNVVALLQKRLQGVEVELVLFDAQSGTRAPLSLADDHPELVA
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHH
HCDDLRLEQVLINLLGNALDATADINSPRISIEIEVADANLSFAVSDNGPGIADDVLPRL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCEEEEECCCCCCCHHHHHHHH
FEPFFTTKEMGQGLGLGLAISSSIARDCGGSLVARNAPGGGALFVLTLRRARVQTSHTPD
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEHHHHHHCCCCCCC
PLTTGS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]