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The map label for this gene is yrhP [H]

Identifier: 91790286

GI number: 91790286

Start: 4707105

End: 4707755

Strand: Reverse

Name: yrhP [H]

Synonym: Bpro_4453

Alternate gene names: 91790286

Gene position: 4707755-4707105 (Counterclockwise)

Preceding gene: 91790287

Following gene: 91790285

Centisome position: 90.53

GC content: 62.37

Gene sequence:

>651_bases
ATGCCTGACTTTCAACACCTGTTGCTTTTTATCGCGGCCGGTTGGTTGCTTAATCTGACGCCGGGCCCCGACGTGCTTTA
CATCGTGACCAACTCGCTGCGCTCGGGTGCGCGCGCCGGGATTGTTGCGGGCCTCGGCATCACGGCTGGCTGTTTTCTCC
ATATTTTTGCGGCGGCTGTAGGCGTCGGCGCGTTGCTGGCCACTTCGGCCATCGCCTTTACCGTGCTCAAGTGGACAGGG
GCGGCTTACCTGCTGTGGATAGGCGCGAAGATCCTGTTGTCCAAAGCGCCGCAGGCCACCACCGACCTCGTCGCGGCGGC
TGCCGCACAGCCGGCACGGCGCCTGAACGTGGTTTTCATGGGAGGCTTCTGGACCAATGTGCTGAACCCCAAGGTCGCGA
TTTTCTTCCTGGCTTTCGTGCCGCAGTTCATCGCACCGGACACCGACAACAAGGCCCTGGCCTTTGTGCTGCTGGGCGTG
CTGTTCAATTTGAACGCCATCCCGGTCAATTCGGGCTGGGCCCTGGCAGCTGCCTGGATGGCCCGGCGTGATGCCGTGCA
GCGCGGCATGCACTGGCTGGACCGCGCAGCCGGCGTCATGTTCATCGGGTTTGGCCTCAAGCTGGCCCTTACCGATAATC
CAACGGACTGA

Upstream 100 bases:

>100_bases
GTTTTGTCACGCACCTCGATGTGGACGCTGCCGGTGTGGACCGCGCCGTGGCCGCGATCCGGCAGTTCTTCCATCTCAAA
GGATAAACAAGGATAAAGCC

Downstream 100 bases:

>100_bases
GTCGTCCCCTCCAGTCCCAGAGTAAAGAAACGAGACGCGTCATGCCCCACACCCACAAAATCACCCCGCAGGAAGCCCTG
CAACGCACCATCGAGCACCG

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MPDFQHLLLFIAAGWLLNLTPGPDVLYIVTNSLRSGARAGIVAGLGITAGCFLHIFAAAVGVGALLATSAIAFTVLKWTG
AAYLLWIGAKILLSKAPQATTDLVAAAAAQPARRLNVVFMGGFWTNVLNPKVAIFFLAFVPQFIAPDTDNKALAFVLLGV
LFNLNAIPVNSGWALAAAWMARRDAVQRGMHWLDRAAGVMFIGFGLKLALTDNPTD

Sequences:

>Translated_216_residues
MPDFQHLLLFIAAGWLLNLTPGPDVLYIVTNSLRSGARAGIVAGLGITAGCFLHIFAAAVGVGALLATSAIAFTVLKWTG
AAYLLWIGAKILLSKAPQATTDLVAAAAAQPARRLNVVFMGGFWTNVLNPKVAIFFLAFVPQFIAPDTDNKALAFVLLGV
LFNLNAIPVNSGWALAAAWMARRDAVQRGMHWLDRAAGVMFIGFGLKLALTDNPTD
>Mature_215_residues
PDFQHLLLFIAAGWLLNLTPGPDVLYIVTNSLRSGARAGIVAGLGITAGCFLHIFAAAVGVGALLATSAIAFTVLKWTGA
AYLLWIGAKILLSKAPQATTDLVAAAAAQPARRLNVVFMGGFWTNVLNPKVAIFFLAFVPQFIAPDTDNKALAFVLLGVL
FNLNAIPVNSGWALAAAWMARRDAVQRGMHWLDRAAGVMFIGFGLKLALTDNPTD

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=194, Percent_Identity=34.020618556701, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1788099, Length=192, Percent_Identity=27.6041666666667, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22889; Mature: 22758

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFQHLLLFIAAGWLLNLTPGPDVLYIVTNSLRSGARAGIVAGLGITAGCFLHIFAAAV
CCCHHHHHHHHHHHHEEECCCCCCEEEEEECCCCCCCCCCHHHHCHHHHHHHHHHHHHHH
GVGALLATSAIAFTVLKWTGAAYLLWIGAKILLSKAPQATTDLVAAAAAQPARRLNVVFM
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHEEEEEE
GGFWTNVLNPKVAIFFLAFVPQFIAPDTDNKALAFVLLGVLFNLNAIPVNSGWALAAAWM
CCHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHH
ARRDAVQRGMHWLDRAAGVMFIGFGLKLALTDNPTD
HHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCC
>Mature Secondary Structure 
PDFQHLLLFIAAGWLLNLTPGPDVLYIVTNSLRSGARAGIVAGLGITAGCFLHIFAAAV
CCHHHHHHHHHHHHEEECCCCCCEEEEEECCCCCCCCCCHHHHCHHHHHHHHHHHHHHH
GVGALLATSAIAFTVLKWTGAAYLLWIGAKILLSKAPQATTDLVAAAAAQPARRLNVVFM
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHEEEEEE
GGFWTNVLNPKVAIFFLAFVPQFIAPDTDNKALAFVLLGVLFNLNAIPVNSGWALAAAWM
CCHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHH
ARRDAVQRGMHWLDRAAGVMFIGFGLKLALTDNPTD
HHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]