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The map label for this gene is trpD

Identifier: 91790285

GI number: 91790285

Start: 4706020

End: 4707063

Strand: Reverse

Name: trpD

Synonym: Bpro_4452

Alternate gene names: 91790285

Gene position: 4707063-4706020 (Counterclockwise)

Preceding gene: 91790286

Following gene: 91790284

Centisome position: 90.52

GC content: 63.98

Gene sequence:

>1044_bases
ATGCCCCACACCCACAAAATCACCCCGCAGGAAGCCCTGCAACGCACCATCGAGCACCGCGAGATCTTTCACGACGAGAT
GCTGCACATCATGCGGCTAATCATGAGCGGCGAGATGTCGCCGGTCATGATGGCGGCGCTGATCACCGGCCTGCGCGTCA
AGAAGGAAACCATCGGTGAGATCACCGCTGCCGCGCAGGTGATGCGCGAGTTTTCGACCAAGGTCCATGTGGCCGACAAA
ACTCACCTGGTGGACATCGTTGGCACGGGTGGCGACGGCTCGCACACCTTCAACATTTCGACCTGCTCGATGTTTGTGGC
GGCGGCGGCGGGCGCCAAGGTCAGCAAGCACGGCGGGCGCAGCGTCAGCAGCAAGTCGGGCAGCGCCGATGTCATGGAAG
CCCTGGGCATCAACATCAACCTGATGCCCGAGGCGATTGCGAAATGCATTGAAGAAGCCGGCGTGGGCTTCATGTTTGCG
CCCAACCACCACCCGGCGATGAAAAACGTCGCGCCCATCCGCAAGGAGCTGGGCGTGCGCACCATTTTCAACATCCTCGG
GCCGCTCACCAACCCGGCCAGCGCCCCGAACATCCTGATGGGCGTGTTCCACCCCGACCTGGTGGGCATCCAGATCCGTG
CGCTGCAGCGCCTGGGCGCCGAGCATGCGCTGGTGGTGTATGGCAAGGACGGCATGGACGAGGTCAGCCTGGGCGCCGCC
ACCATCGTGGGGGAGCTGAAAAACGGCGAGATCACTGAATACGAAATCCACCCCGAGGACTTCAGCATGACCATGGCCAG
CAACCGCGCGCTGCGCGTCGAAACGCCAGAGCAGTCCAAAGCCATGCTGCTGGGCGTGCTGGACAACCAGCCGGGCGCGG
CGCGCGACATCGTGATCCTCAATGCCGGCGCGGCGCTGTATGCCGCCAATGTGGCCTCCTCGATGCAGGAGGGCATCGTC
AAGGCGCGTGCCGCGCTCGAGTCCGGTGCGGCCAAGGCCCGCCTCGCGCAGCTTGTTTCCATCACCCAAACCCTGGCAGC
CTGA

Upstream 100 bases:

>100_bases
GCGTCATGTTCATCGGGTTTGGCCTCAAGCTGGCCCTTACCGATAATCCAACGGACTGAGTCGTCCCCTCCAGTCCCAGA
GTAAAGAAACGAGACGCGTC

Downstream 100 bases:

>100_bases
ACACCATGTCCGACATCCTCGACAAGATCATTGCCGTCAAGCGCGAAGAAATCGCGCAGGCCATCAAACGCAAGCCGCTG
GCCGTGGTGCGCGAAGACGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MPHTHKITPQEALQRTIEHREIFHDEMLHIMRLIMSGEMSPVMMAALITGLRVKKETIGEITAAAQVMREFSTKVHVADK
THLVDIVGTGGDGSHTFNISTCSMFVAAAAGAKVSKHGGRSVSSKSGSADVMEALGININLMPEAIAKCIEEAGVGFMFA
PNHHPAMKNVAPIRKELGVRTIFNILGPLTNPASAPNILMGVFHPDLVGIQIRALQRLGAEHALVVYGKDGMDEVSLGAA
TIVGELKNGEITEYEIHPEDFSMTMASNRALRVETPEQSKAMLLGVLDNQPGAARDIVILNAGAALYAANVASSMQEGIV
KARAALESGAAKARLAQLVSITQTLAA

Sequences:

>Translated_347_residues
MPHTHKITPQEALQRTIEHREIFHDEMLHIMRLIMSGEMSPVMMAALITGLRVKKETIGEITAAAQVMREFSTKVHVADK
THLVDIVGTGGDGSHTFNISTCSMFVAAAAGAKVSKHGGRSVSSKSGSADVMEALGININLMPEAIAKCIEEAGVGFMFA
PNHHPAMKNVAPIRKELGVRTIFNILGPLTNPASAPNILMGVFHPDLVGIQIRALQRLGAEHALVVYGKDGMDEVSLGAA
TIVGELKNGEITEYEIHPEDFSMTMASNRALRVETPEQSKAMLLGVLDNQPGAARDIVILNAGAALYAANVASSMQEGIV
KARAALESGAAKARLAQLVSITQTLAA
>Mature_346_residues
PHTHKITPQEALQRTIEHREIFHDEMLHIMRLIMSGEMSPVMMAALITGLRVKKETIGEITAAAQVMREFSTKVHVADKT
HLVDIVGTGGDGSHTFNISTCSMFVAAAAGAKVSKHGGRSVSSKSGSADVMEALGININLMPEAIAKCIEEAGVGFMFAP
NHHPAMKNVAPIRKELGVRTIFNILGPLTNPASAPNILMGVFHPDLVGIQIRALQRLGAEHALVVYGKDGMDEVSLGAAT
IVGELKNGEITEYEIHPEDFSMTMASNRALRVETPEQSKAMLLGVLDNQPGAARDIVILNAGAALYAANVASSMQEGIVK
ARAALESGAAKARLAQLVSITQTLAA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=283, Percent_Identity=41.696113074205, Blast_Score=202, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320561, Length=366, Percent_Identity=29.7814207650273, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_POLSJ (Q123F3)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_551237.1
- ProteinModelPortal:   Q123F3
- SMR:   Q123F3
- STRING:   Q123F3
- GeneID:   4012878
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_4452
- NMPDR:   fig|296591.1.peg.1056
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q123F3
- ProtClustDB:   PRK00188
- BioCyc:   PSP296591:BPRO_4452-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36880; Mature: 36749

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHTHKITPQEALQRTIEHREIFHDEMLHIMRLIMSGEMSPVMMAALITGLRVKKETIGE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ITAAAQVMREFSTKVHVADKTHLVDIVGTGGDGSHTFNISTCSMFVAAAAGAKVSKHGGR
HHHHHHHHHHHCCEEEEECCEEEEEEEECCCCCCEEEEHHHHHHHHHHHCCCCHHHCCCC
SVSSKSGSADVMEALGININLMPEAIAKCIEEAGVGFMFAPNHHPAMKNVAPIRKELGVR
CCCCCCCCHHHHHHHCCCEEECHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHH
TIFNILGPLTNPASAPNILMGVFHPDLVGIQIRALQRLGAEHALVVYGKDGMDEVSLGAA
HHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCHH
TIVGELKNGEITEYEIHPEDFSMTMASNRALRVETPEQSKAMLLGVLDNQPGAARDIVIL
HHEEECCCCCEEEEEECCCCCEEEEECCCEEEEECCCCCCEEEEEEECCCCCCCEEEEEE
NAGAALYAANVASSMQEGIVKARAALESGAAKARLAQLVSITQTLAA
ECCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PHTHKITPQEALQRTIEHREIFHDEMLHIMRLIMSGEMSPVMMAALITGLRVKKETIGE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ITAAAQVMREFSTKVHVADKTHLVDIVGTGGDGSHTFNISTCSMFVAAAAGAKVSKHGGR
HHHHHHHHHHHCCEEEEECCEEEEEEEECCCCCCEEEEHHHHHHHHHHHCCCCHHHCCCC
SVSSKSGSADVMEALGININLMPEAIAKCIEEAGVGFMFAPNHHPAMKNVAPIRKELGVR
CCCCCCCCHHHHHHHCCCEEECHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHH
TIFNILGPLTNPASAPNILMGVFHPDLVGIQIRALQRLGAEHALVVYGKDGMDEVSLGAA
HHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCHH
TIVGELKNGEITEYEIHPEDFSMTMASNRALRVETPEQSKAMLLGVLDNQPGAARDIVIL
HHEEECCCCCEEEEEECCCCCEEEEECCCEEEEECCCCCCEEEEEEECCCCCCCEEEEEE
NAGAALYAANVASSMQEGIVKARAALESGAAKARLAQLVSITQTLAA
ECCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA