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The map label for this gene is appC [H]

Identifier: 91790236

GI number: 91790236

Start: 4646344

End: 4647279

Strand: Reverse

Name: appC [H]

Synonym: Bpro_4403

Alternate gene names: 91790236

Gene position: 4647279-4646344 (Counterclockwise)

Preceding gene: 91790237

Following gene: 91790235

Centisome position: 89.37

GC content: 62.18

Gene sequence:

>936_bases
GTGAACCGCAAATCTCTCAAGGCCCCCGCCGCGACCCCTGCCGGAGGCCGGGCGCTGCGCTGGGCGGGCGTGCTACGCCG
CGAGCTGGCCAACAATTTGCGGGTCATTCGAGCGGACCGACTGGGTAGCTTCGGCGCTGTGGTGATCGTTGTCGCGGCGC
TCGTGGCAGTGTTCGGCCCGTGGCTGATCCCGCACGATCCCTACGAGTCGCTACGGATGGCCGACGGACGCATGGCCGTG
CTACAGCGTCCCAGTTTGGAGTTTCCGCTCGGCACGACCAATCTCGCGCGTGACCTCCTCTCACAGATGATCGTGGCGAC
ACGCACGACCATGATCATCGGGCTCGTCAGCGGGCTCATCTCCATTGTCATCGGCGCCAACATCGGACTGATTTCCGGCT
ACTACGGCGGACGCGTGGACAACGTGCTGATGCGGCTGACCGACATCGTCTATGGCATGCCGTTCCTTCCCTTCATCATC
GTATTGATCTCTCTGTTCGGGCGTTCCATCGGCTTCGTGATGCTGGCGATCGTGGTGATTGTCTGGCGCACATCCGCGCG
CGTAGTCCGCGCCCAGACGATGGCGATCAAGCAGCGCCAATTTGTAGCGTTCGCAAAGGCACGAGGCGCGAGCGACATGC
GCATCATCTATCGGCACATTGCCCCTAACATCCTGCCGCTGCTGCTGCTTTACACCTCGTTCAACATTGCCTGGGCGATT
GTGACCGAAGCCTCTGCCAGCTTCCTGGGCTTCAGTGACCCCAACGCGATAACGTGGGGCAGCATCCTGCAGGACCTATG
GGCATCAGGCTACACGCGCAGCGCCTGGTGGTGGTTCATCGCGCCATCGGGAGCGATCGTGTTGCTCGTCAGCGCCTTCG
TGTTCGTGAGCCGCGCTTACGAAGTTGTCGCTAACCCACGATTGGGGGACCGCTAA

Upstream 100 bases:

>100_bases
GGGTAGTGCACTTTCCCGGCACTACCGGCTTGGGTATCCAGGTTGACGAGCCTCACGTTCGCCGCCTGGCAGTGGACAGC
TTCATTCTTGGGGCACAACG

Downstream 100 bases:

>100_bases
CATGTTGCTCGAAGCCCGCAATCTGCGAGTGACTTATCGGAGCGCCCACGGAGATGTGCGCGCCGTCGACGGACTCGATC
TGGCAATCAACGAATCTGAA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNRKSLKAPAATPAGGRALRWAGVLRRELANNLRVIRADRLGSFGAVVIVVAALVAVFGPWLIPHDPYESLRMADGRMAV
LQRPSLEFPLGTTNLARDLLSQMIVATRTTMIIGLVSGLISIVIGANIGLISGYYGGRVDNVLMRLTDIVYGMPFLPFII
VLISLFGRSIGFVMLAIVVIVWRTSARVVRAQTMAIKQRQFVAFAKARGASDMRIIYRHIAPNILPLLLLYTSFNIAWAI
VTEASASFLGFSDPNAITWGSILQDLWASGYTRSAWWWFIAPSGAIVLLVSAFVFVSRAYEVVANPRLGDR

Sequences:

>Translated_311_residues
MNRKSLKAPAATPAGGRALRWAGVLRRELANNLRVIRADRLGSFGAVVIVVAALVAVFGPWLIPHDPYESLRMADGRMAV
LQRPSLEFPLGTTNLARDLLSQMIVATRTTMIIGLVSGLISIVIGANIGLISGYYGGRVDNVLMRLTDIVYGMPFLPFII
VLISLFGRSIGFVMLAIVVIVWRTSARVVRAQTMAIKQRQFVAFAKARGASDMRIIYRHIAPNILPLLLLYTSFNIAWAI
VTEASASFLGFSDPNAITWGSILQDLWASGYTRSAWWWFIAPSGAIVLLVSAFVFVSRAYEVVANPRLGDR
>Mature_311_residues
MNRKSLKAPAATPAGGRALRWAGVLRRELANNLRVIRADRLGSFGAVVIVVAALVAVFGPWLIPHDPYESLRMADGRMAV
LQRPSLEFPLGTTNLARDLLSQMIVATRTTMIIGLVSGLISIVIGANIGLISGYYGGRVDNVLMRLTDIVYGMPFLPFII
VLISLFGRSIGFVMLAIVVIVWRTSARVVRAQTMAIKQRQFVAFAKARGASDMRIIYRHIAPNILPLLLLYTSFNIAWAI
VTEASASFLGFSDPNAITWGSILQDLWASGYTRSAWWWFIAPSGAIVLLVSAFVFVSRAYEVVANPRLGDR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=279, Percent_Identity=31.8996415770609, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787054, Length=281, Percent_Identity=28.4697508896797, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789964, Length=262, Percent_Identity=32.824427480916, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787498, Length=297, Percent_Identity=30.3030303030303, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789889, Length=250, Percent_Identity=29.2, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788505, Length=224, Percent_Identity=30.8035714285714, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787549, Length=246, Percent_Identity=25.609756097561, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34106; Mature: 34106

Theoretical pI: Translated: 11.69; Mature: 11.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRKSLKAPAATPAGGRALRWAGVLRRELANNLRVIRADRLGSFGAVVIVVAALVAVFGP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCC
WLIPHDPYESLRMADGRMAVLQRPSLEFPLGTTNLARDLLSQMIVATRTTMIIGLVSGLI
CCCCCCCHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIVIGANIGLISGYYGGRVDNVLMRLTDIVYGMPFLPFIIVLISLFGRSIGFVMLAIVVI
HHHHCCCCCEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VWRTSARVVRAQTMAIKQRQFVAFAKARGASDMRIIYRHIAPNILPLLLLYTSFNIAWAI
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHEEEE
VTEASASFLGFSDPNAITWGSILQDLWASGYTRSAWWWFIAPSGAIVLLVSAFVFVSRAY
EECCCHHHCCCCCCCCEEHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
EVVANPRLGDR
HHHCCCCCCCC
>Mature Secondary Structure
MNRKSLKAPAATPAGGRALRWAGVLRRELANNLRVIRADRLGSFGAVVIVVAALVAVFGP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCC
WLIPHDPYESLRMADGRMAVLQRPSLEFPLGTTNLARDLLSQMIVATRTTMIIGLVSGLI
CCCCCCCHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIVIGANIGLISGYYGGRVDNVLMRLTDIVYGMPFLPFIIVLISLFGRSIGFVMLAIVVI
HHHHCCCCCEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VWRTSARVVRAQTMAIKQRQFVAFAKARGASDMRIIYRHIAPNILPLLLLYTSFNIAWAI
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHEEEE
VTEASASFLGFSDPNAITWGSILQDLWASGYTRSAWWWFIAPSGAIVLLVSAFVFVSRAY
EECCCHHHCCCCCCCCEEHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
EVVANPRLGDR
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]