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The map label for this gene is sufS [C]

Identifier: 91790110

GI number: 91790110

Start: 4504198

End: 4505553

Strand: Direct

Name: sufS [C]

Synonym: Bpro_4272

Alternate gene names: 91790110

Gene position: 4504198-4505553 (Clockwise)

Preceding gene: 91790109

Following gene: 91790111

Centisome position: 86.61

GC content: 69.25

Gene sequence:

>1356_bases
ATGAACGCCGCCGGGCCGTCCCAAGGCGCGAAGGCCCCCTTGGGGGGCAGCGCAGCACACGAAGTGGCAAGCGTGGGGGC
ACGTATGAACGCCCCAGTGAATGCGAAAGAACTGACTGCACGCGCCAGCGCGCCCGAGACAGTCCTGGCAGTGGCGCGGC
TGCGGCAGGATTTCCCCATCCTGCACCGGACCGTGCACGGCAAGCCCCTGGTCTACCTGGACAACGCGGCCACCAGCCAG
AAGCCGCAGTACGTGATCGACTGCGAGGCGCGCTACTACGCCGAGCTGAACGCCAACATCCACCGCGGCGTGCACAGCCT
GAGCCAGCAGGCGACCGAGGCCTATGAGGCGGCACGCGACACGGTGCAGCGCTTCATCCATGCAGCCCGCCGCGAGGAAA
TCGTGTTCGTGCGCGGCACCACCGAGGCGATCAACCTGGTGGCGGCGAGCTACGGCCAGCGCCTGCGGCCCGGCGACGAA
ATCCTGATCACCGAGATGGAGCACCACTCCAACATCGTGCCATGGCAGCTGCTGTGCGAGCGCACGGGCGCGGTGCTGCG
CGTCGCGCCCATCGACGACGCCGGCGAGTTGCGCCTCGATGAGTTCGAGCGCCTGCTGGGCCCGGCGACACGCATCGTCG
CGCTCACGCAGCTGTCGAACGCGCTCGGCAGCATCAACCCGGTGCAGCGCCTCGTCGCGCTTGCCCATGCGGTGGGGGCG
GTGGTGCTGGTCGATGGCGCCCAGGCGGTGGCCCACCTGCCGGTTGACGTCCAGGCGCTCGACTGCGATTTCTACGCCTT
CTCCGGCCACAAGCTCTACGGCCCGACCGGCATCGGCGTGCTCTACGGCAAGGCGGCGCTGCTGGACGCCATGCCGCCCT
GGCAGGGCGGCGGCGACATGATCCGCGAGGTCACCTTCGCCCGGACGACATACAACGACCTGCCGTACAAGTTCGAGGCC
GGCACCCCGCATATCGCGGGCGGCATCGCCCTGGGGGCGGCGATCGACTATGTGGGCATGGTGGGTTTGCCCGCCATCGC
CGCCCACGAACACGCGCTGCTGGCCTACGCCACCGAACAGGCGGCCGGAATGGCCGGCCTGCGCCTCATCGGCACCGCCC
GGGACAAGGCGAGCATCCTGTCGTTCACCGTGGAGGGCGTGCACCCGCACGATGTCGGCACCATCCTCGACGACGAGGGG
GTGGCGGTGCGCGCCGGCCACCATTGCGCCATGCCGGTGATGGCGCATTTCGGCGTGCCCGCCACGGTGCGCGCCTCGTT
CGCCCTCTACAACACAGTGGAAGAAGTGGATGTGCTGCTGCGCGCGATCCGCAGGGCGCAGGAGGTATTTGGCTGA

Upstream 100 bases:

>100_bases
TCGCCGAGGAAGTGGTTGACCGGGTGGGCATTGCGCCGCTGCGGGCGCGGCTGGAGAAGCTGCTGCTGGGGCGCCTGCCC
GAGCGGGTGAAGGAGTTGTT

Downstream 100 bases:

>100_bases
TGTCTGACTTGCGCGATCTGTATCAGGAACTCATCGTTGACCACTACCGCCACCCGCACAATTTCGGGCCACTGGCGGGG
GCCAACCGCCGCGCCGAGGG

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MNAAGPSQGAKAPLGGSAAHEVASVGARMNAPVNAKELTARASAPETVLAVARLRQDFPILHRTVHGKPLVYLDNAATSQ
KPQYVIDCEARYYAELNANIHRGVHSLSQQATEAYEAARDTVQRFIHAARREEIVFVRGTTEAINLVAASYGQRLRPGDE
ILITEMEHHSNIVPWQLLCERTGAVLRVAPIDDAGELRLDEFERLLGPATRIVALTQLSNALGSINPVQRLVALAHAVGA
VVLVDGAQAVAHLPVDVQALDCDFYAFSGHKLYGPTGIGVLYGKAALLDAMPPWQGGGDMIREVTFARTTYNDLPYKFEA
GTPHIAGGIALGAAIDYVGMVGLPAIAAHEHALLAYATEQAAGMAGLRLIGTARDKASILSFTVEGVHPHDVGTILDDEG
VAVRAGHHCAMPVMAHFGVPATVRASFALYNTVEEVDVLLRAIRRAQEVFG

Sequences:

>Translated_451_residues
MNAAGPSQGAKAPLGGSAAHEVASVGARMNAPVNAKELTARASAPETVLAVARLRQDFPILHRTVHGKPLVYLDNAATSQ
KPQYVIDCEARYYAELNANIHRGVHSLSQQATEAYEAARDTVQRFIHAARREEIVFVRGTTEAINLVAASYGQRLRPGDE
ILITEMEHHSNIVPWQLLCERTGAVLRVAPIDDAGELRLDEFERLLGPATRIVALTQLSNALGSINPVQRLVALAHAVGA
VVLVDGAQAVAHLPVDVQALDCDFYAFSGHKLYGPTGIGVLYGKAALLDAMPPWQGGGDMIREVTFARTTYNDLPYKFEA
GTPHIAGGIALGAAIDYVGMVGLPAIAAHEHALLAYATEQAAGMAGLRLIGTARDKASILSFTVEGVHPHDVGTILDDEG
VAVRAGHHCAMPVMAHFGVPATVRASFALYNTVEEVDVLLRAIRRAQEVFG
>Mature_451_residues
MNAAGPSQGAKAPLGGSAAHEVASVGARMNAPVNAKELTARASAPETVLAVARLRQDFPILHRTVHGKPLVYLDNAATSQ
KPQYVIDCEARYYAELNANIHRGVHSLSQQATEAYEAARDTVQRFIHAARREEIVFVRGTTEAINLVAASYGQRLRPGDE
ILITEMEHHSNIVPWQLLCERTGAVLRVAPIDDAGELRLDEFERLLGPATRIVALTQLSNALGSINPVQRLVALAHAVGA
VVLVDGAQAVAHLPVDVQALDCDFYAFSGHKLYGPTGIGVLYGKAALLDAMPPWQGGGDMIREVTFARTTYNDLPYKFEA
GTPHIAGGIALGAAIDYVGMVGLPAIAAHEHALLAYATEQAAGMAGLRLIGTARDKASILSFTVEGVHPHDVGTILDDEG
VAVRAGHHCAMPVMAHFGVPATVRASFALYNTVEEVDVLLRAIRRAQEVFG

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=215, Percent_Identity=29.7674418604651, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI156713448, Length=427, Percent_Identity=27.6346604215457, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1787970, Length=406, Percent_Identity=53.6945812807882, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI1789175, Length=405, Percent_Identity=44.1975308641975, Blast_Score=345, Evalue=5e-96,
Organism=Escherichia coli, GI48994898, Length=182, Percent_Identity=35.1648351648352, Blast_Score=95, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI25143064, Length=213, Percent_Identity=29.5774647887324, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI193211090, Length=411, Percent_Identity=22.8710462287105, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319831, Length=260, Percent_Identity=27.6923076923077, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI20129463, Length=266, Percent_Identity=31.203007518797, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 48089; Mature: 48089

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAGPSQGAKAPLGGSAAHEVASVGARMNAPVNAKELTARASAPETVLAVARLRQDFPI
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCH
LHRTVHGKPLVYLDNAATSQKPQYVIDCEARYYAELNANIHRGVHSLSQQATEAYEAARD
HHHHCCCCCEEEECCCCCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
TVQRFIHAARREEIVFVRGTTEAINLVAASYGQRLRPGDEILITEMEHHSNIVPWQLLCE
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEEEHHCCCCCHHHHHHH
RTGAVLRVAPIDDAGELRLDEFERLLGPATRIVALTQLSNALGSINPVQRLVALAHAVGA
CCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCE
VVLVDGAQAVAHLPVDVQALDCDFYAFSGHKLYGPTGIGVLYGKAALLDAMPPWQGGGDM
EEEEECCHHHEECCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCCCCCHHH
IREVTFARTTYNDLPYKFEAGTPHIAGGIALGAAIDYVGMVGLPAIAAHEHALLAYATEQ
HHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEHHH
AAGMAGLRLIGTARDKASILSFTVEGVHPHDVGTILDDEGVAVRAGHHCAMPVMAHFGVP
HCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCEECCCCCEEECCCCCHHHHHHHCCCC
ATVRASFALYNTVEEVDVLLRAIRRAQEVFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAAGPSQGAKAPLGGSAAHEVASVGARMNAPVNAKELTARASAPETVLAVARLRQDFPI
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCH
LHRTVHGKPLVYLDNAATSQKPQYVIDCEARYYAELNANIHRGVHSLSQQATEAYEAARD
HHHHCCCCCEEEECCCCCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
TVQRFIHAARREEIVFVRGTTEAINLVAASYGQRLRPGDEILITEMEHHSNIVPWQLLCE
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEEEHHCCCCCHHHHHHH
RTGAVLRVAPIDDAGELRLDEFERLLGPATRIVALTQLSNALGSINPVQRLVALAHAVGA
CCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCE
VVLVDGAQAVAHLPVDVQALDCDFYAFSGHKLYGPTGIGVLYGKAALLDAMPPWQGGGDM
EEEEECCHHHEECCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCCCCCHHH
IREVTFARTTYNDLPYKFEAGTPHIAGGIALGAAIDYVGMVGLPAIAAHEHALLAYATEQ
HHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEHHH
AAGMAGLRLIGTARDKASILSFTVEGVHPHDVGTILDDEGVAVRAGHHCAMPVMAHFGVP
HCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCEECCCCCEEECCCCCHHHHHHHCCCC
ATVRASFALYNTVEEVDVLLRAIRRAQEVFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA