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The map label for this gene is can [H]

Identifier: 91790027

GI number: 91790027

Start: 4402693

End: 4403394

Strand: Reverse

Name: can [H]

Synonym: Bpro_4189

Alternate gene names: 91790027

Gene position: 4403394-4402693 (Counterclockwise)

Preceding gene: 91790028

Following gene: 91790026

Centisome position: 84.68

GC content: 64.39

Gene sequence:

>702_bases
GTGAGGCCGCCCGGCCTGCAACTGATTAAGATCGTTCCCATGACAGCATCACTTGAAAGCCTTTTCAGCCATAACCGCGC
CTGGGCGGCACAAATGGAAGCCGAACGGCCGGGCTTTTTCACCAGCCTGGTCAAGCAGCAGACTCCCAAATACATGTGGA
TTGGCTGCTCCGACAGCCGCGTGCCGGCCAACCAGATCACCGGGCTGGAGCCGGGCGAGGTGTTTGTCCACCGCAACGTG
GCCAACATCGTGGTGCACTCCGACCTCAACGCCCTGTCCGCGATCCAGTTCGCGGTGGAGCGGCTCAAGGTCAAGGACAT
CATGGTGGTGGGTCATTACGGCTGCTCGGGCGTGCAGGCCGCGCTGGAAGGCGCGCGCATTGGCCTGGCCGACAACTGGA
TACGCCACATCCAGGACGTGCGCCACCGGCACCGCCAGCTGCTCGACAGCCTGCCCGATGCGGTGCGGGCCAATGCCTTG
TGCGACATCAACGTGATCGAGCAGGTGGTGAACGTGTCGGTCAGCACCGTGATGGTGGACGCCTGGGCCCGCAGCCAGGA
CGTCACTGTGCACGGCTGGGCATTCGGTGTGCACGACGGCCTGCTGCAGGACCTGCAGATGAGCGTCTCAGACCCCGAGG
AGCTGGATGCCCGCTACCGGCAGGCGGTGGACCGCGTCTGGGACCTCTGGAACAGCCGGTAA

Upstream 100 bases:

>100_bases
GCACCAGCGAGATCCGCCGCATGCTGATAGGCCGTGAACTGTTTGCCGAAACCTGCTGAGGCCCGTACCCTGGCGCAACG
AATGGCCAAGGGATGACCCT

Downstream 100 bases:

>100_bases
CGTCAGATAACGCCAGACAGCGCCAGAACCAGGACTCGCCGTGTTTCCCCAGCGCCTTGACTCCACCATCGCCTACGACA
TTGCGAAAGCGATGATGGAC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRPPGLQLIKIVPMTASLESLFSHNRAWAAQMEAERPGFFTSLVKQQTPKYMWIGCSDSRVPANQITGLEPGEVFVHRNV
ANIVVHSDLNALSAIQFAVERLKVKDIMVVGHYGCSGVQAALEGARIGLADNWIRHIQDVRHRHRQLLDSLPDAVRANAL
CDINVIEQVVNVSVSTVMVDAWARSQDVTVHGWAFGVHDGLLQDLQMSVSDPEELDARYRQAVDRVWDLWNSR

Sequences:

>Translated_233_residues
MRPPGLQLIKIVPMTASLESLFSHNRAWAAQMEAERPGFFTSLVKQQTPKYMWIGCSDSRVPANQITGLEPGEVFVHRNV
ANIVVHSDLNALSAIQFAVERLKVKDIMVVGHYGCSGVQAALEGARIGLADNWIRHIQDVRHRHRQLLDSLPDAVRANAL
CDINVIEQVVNVSVSTVMVDAWARSQDVTVHGWAFGVHDGLLQDLQMSVSDPEELDARYRQAVDRVWDLWNSR
>Mature_233_residues
MRPPGLQLIKIVPMTASLESLFSHNRAWAAQMEAERPGFFTSLVKQQTPKYMWIGCSDSRVPANQITGLEPGEVFVHRNV
ANIVVHSDLNALSAIQFAVERLKVKDIMVVGHYGCSGVQAALEGARIGLADNWIRHIQDVRHRHRQLLDSLPDAVRANAL
CDINVIEQVVNVSVSTVMVDAWARSQDVTVHGWAFGVHDGLLQDLQMSVSDPEELDARYRQAVDRVWDLWNSR

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=209, Percent_Identity=51.6746411483254, Blast_Score=255, Evalue=2e-69,
Organism=Escherichia coli, GI1786534, Length=175, Percent_Identity=31.4285714285714, Blast_Score=80, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6324292, Length=197, Percent_Identity=31.9796954314721, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 26096; Mature: 26096

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPPGLQLIKIVPMTASLESLFSHNRAWAAQMEAERPGFFTSLVKQQTPKYMWIGCSDSR
CCCCCCEEEEEECCHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCC
VPANQITGLEPGEVFVHRNVANIVVHSDLNALSAIQFAVERLKVKDIMVVGHYGCSGVQA
CCHHHCCCCCCCCEEEECCHHHEEEECCHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHH
ALEGARIGLADNWIRHIQDVRHRHRQLLDSLPDAVRANALCDINVIEQVVNVSVSTVMVD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHCCHHHHHEEE
AWARSQDVTVHGWAFGVHDGLLQDLQMSVSDPEELDARYRQAVDRVWDLWNSR
HHCCCCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRPPGLQLIKIVPMTASLESLFSHNRAWAAQMEAERPGFFTSLVKQQTPKYMWIGCSDSR
CCCCCCEEEEEECCHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCCC
VPANQITGLEPGEVFVHRNVANIVVHSDLNALSAIQFAVERLKVKDIMVVGHYGCSGVQA
CCHHHCCCCCCCCEEEECCHHHEEEECCHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHH
ALEGARIGLADNWIRHIQDVRHRHRQLLDSLPDAVRANALCDINVIEQVVNVSVSTVMVD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHCCHHHHHEEE
AWARSQDVTVHGWAFGVHDGLLQDLQMSVSDPEELDARYRQAVDRVWDLWNSR
HHCCCCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]