Click here to switch to the map view.

The map label for this gene is fadN [H]

Identifier: 91789796

GI number: 91789796

Start: 4146149

End: 4148605

Strand: Reverse

Name: fadN [H]

Synonym: Bpro_3956

Alternate gene names: 91789796

Gene position: 4148605-4146149 (Counterclockwise)

Preceding gene: 91789797

Following gene: 91789795

Centisome position: 79.78

GC content: 63.37

Gene sequence:

>2457_bases
ATGCAAAAATTCACAGTCAAAAGAGTAGCCGTGCTCGGCGCCGGTGTGATGGGCGCGCAGATCGCCGCTCATCTGGTCAA
TGTCAAGGTGCCCGTGGTGCTGTTTGACCTGCCCGCAAAAGACAACGATGGGGGCGGGGCCCCGTCGTCTTCCAAGTCTT
CGAAAAATGGCATCGTCACCAAGGCGATCGAAGGCCTGAAAAAGCTCAAGCCCGCGCCGCTGGGCGTACCCGAGGATGCG
GCGCTGATCCAGCCGGCCAACTACGAAGAGCACATGGAGCAGCTGTTGGAGTGCGACCTCATCATCGAGGCGATTGCCGA
GCGCATGGACTGGAAGACCGACCTGTACCACAAGATCGCCCCCTTCATTGCCGAAGGCGCGATTGTGGCCAGCAACACCT
CGGGCCTGTCGATCACCAAACTCAGCGAAGCCCTGCCCGAATCGATCAAGCCGCGTTTTTGCGGCATCCACTTTTTCAAT
CCGCCGCGCTACATGACACTGGTGGAGCTGATCAACACGCCCACCACCGGGCCGAAAGTGCTCGACGACCTGGAAGCCTT
TGCGGTCAGCGCACTGGGCAAGGGCGTGATCCGCGCGCACGACACGCCCAACTTCATTGCCAACCGCGTCGGCATTGCCG
GCATGCTGGCAACCATCAAGGAGGCCGAGACCTTTGGCCTGACGTATGACGTGGTTGACGACCTGACCGGCAAGAAACTG
GGCCGCGCCAGCTCCGGCACCTTCCGCACTGCTGACGTGGTGGGCCTGGACACCATGGCGCATGTGATCAGGACGCTGCA
GGACAATCTCGGTCCCGGCAAGGTCGAAGATCCGTTCTCGGACATCTACGGCACGCCGCCGGTCCTGGCGAAACTGCTGG
AATCCAAAAGCCTGGGCCAGAAAACCGGCGCCGGCTTTTACAAGAAGGTCGGCCGGGACATCCTGCGCCTCGACCCCGAA
AGCATGGAGTACGTGGCCGCAGGCGCCAAGGCCAACGAGGTCGTCGGTCGCATGCTGAAAAAACCGGCCGGCGAGCGGCT
GAAGCTGCTGCGCGAGGCCGAGGGCGCCGAAGCGCGATTCCTCTGGGCCATCCTGCGCGACCAGTTCCACTATGCCGCGG
TGCACCTCGAAAGCATTGCCGAAACCGCGCGCGACATCGACTTTGCGATGCGCTGGGGCTTTGGCGCCAAGCAAGGCCCG
TTCGAGTTGTGGCAGCAGGCCGGCTGGCAGCAGGTGGCCAGCTGGATCCAGGAAGACATTGAGGCGGGCAAGGCCTTGAG
CAAAGCGCCGCTGCCCGACTGGGTGTTCAAGGGCCCGGTGGCCGACGCGGGCGGTGTGCACACCGCGGAAGGTTCGTGGA
GCGCCTCGGCGCAAAAATTCATTCCGCGCCGCAAGCTGCCCGTTTATGAGCGCCAGTATTTCCCCGAGGACGTGCTGGGT
GCCAACGCCCCGGCTTTCGAAACCGCCGGTACCACGCTGCATGAAGACGATGCCATCCGCCTCTGGACGCTGGACGGTGC
GAACGGAGAAAAAGGCGACGTGCTGATTGCCAGCATCAAGACCAAGATGCACGCCATCAGCCCCGATGTGGCGGAAGGCC
TGGCGATGGGCGTGGACCTCGCCGAGAAGGGTTACAAGGGCATGGTCATCTGGTCCAACGACGAGATGTTCTCGGCCGGC
GCCGACCTGCAGGCCATGCTGCCCGCCTTCATGATGGGCGGCGCCAGGTCGATTGAAGGCGCGGAAGCCGAACTGCAAAA
CGTCATGCTCAAGCTGCGCTACGCGGCTGTGCCTGTCGTGTCGGCAATTCGCGGCCTGGCGCTGGGCGGTGGCTGCGAGA
TGGCCGTGTACTCGGCCAAACGCGTCGCCGCGATGGAAAGCTACATCGGCTTGGTGGAAGTCGGTGTCGGCCTCGTGCCC
GGTGCCGGCGGCCTGGCGTACATTGCGCGCCGCGCGGCAGAAAACGCCGCCACGTCCACCAACAAGGACATATTGCCTTT
CCTGACCGAAGACTTCACCGCCGCCGCCATGGCCAAGGTGGGCACCAGCGCGATTGAAAGCCGCAAGATCGGCTACCTGC
TGGACAGCGACGTCATCGTGCCGAACAAGGACGAACTGCTGTTCGTGGCGCTGAACGAGGCCCGCGCCCTGTTCAACTCG
GGCTACCGCGCGCCGCACAGGCGGCCCTTCCCGGTCGTGGGCCGCAACGGCCTGGCCACCATCAAGGGCCAGCTGGTCAA
CATGCGCGACGGCGGCTTCATCAGCGCGCATGACTTTCACATCGCCGGCCTGATCGCCAACGTGGTGTGTGGTGGCGACG
TGGATGCCGGCACGCTGGTCACGGAGGAATATCTGATGACGCTGGAACGCAAGGCCTTCTGTTCGCTGCTCGAAAACCCG
AAAACGCAGGAACGCATCATGGGCATGATGAGCACCGGCAAACCGGTGAGGAATTGA

Upstream 100 bases:

>100_bases
TTGAACCATGCGGGGTCAGCCCCACCCAGTCATCTCCGCTTTATCCCCTCGCCCTCTGGGAGAGGGTTAGGGTGAGGGCT
CTCCGATAAAGGAACACAAC

Downstream 100 bases:

>100_bases
TGACTGATTTGACGAAGACATCTCCTAACCGCCTGGAGCGCCAGCTCGAGCGCCTGTCTGAGGTGCCGGCCTTTGCCCGC
ACCTGGTTTCGCAGCGTGAT

Product: 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 818; Mature: 818

Protein sequence:

>818_residues
MQKFTVKRVAVLGAGVMGAQIAAHLVNVKVPVVLFDLPAKDNDGGGAPSSSKSSKNGIVTKAIEGLKKLKPAPLGVPEDA
ALIQPANYEEHMEQLLECDLIIEAIAERMDWKTDLYHKIAPFIAEGAIVASNTSGLSITKLSEALPESIKPRFCGIHFFN
PPRYMTLVELINTPTTGPKVLDDLEAFAVSALGKGVIRAHDTPNFIANRVGIAGMLATIKEAETFGLTYDVVDDLTGKKL
GRASSGTFRTADVVGLDTMAHVIRTLQDNLGPGKVEDPFSDIYGTPPVLAKLLESKSLGQKTGAGFYKKVGRDILRLDPE
SMEYVAAGAKANEVVGRMLKKPAGERLKLLREAEGAEARFLWAILRDQFHYAAVHLESIAETARDIDFAMRWGFGAKQGP
FELWQQAGWQQVASWIQEDIEAGKALSKAPLPDWVFKGPVADAGGVHTAEGSWSASAQKFIPRRKLPVYERQYFPEDVLG
ANAPAFETAGTTLHEDDAIRLWTLDGANGEKGDVLIASIKTKMHAISPDVAEGLAMGVDLAEKGYKGMVIWSNDEMFSAG
ADLQAMLPAFMMGGARSIEGAEAELQNVMLKLRYAAVPVVSAIRGLALGGGCEMAVYSAKRVAAMESYIGLVEVGVGLVP
GAGGLAYIARRAAENAATSTNKDILPFLTEDFTAAAMAKVGTSAIESRKIGYLLDSDVIVPNKDELLFVALNEARALFNS
GYRAPHRRPFPVVGRNGLATIKGQLVNMRDGGFISAHDFHIAGLIANVVCGGDVDAGTLVTEEYLMTLERKAFCSLLENP
KTQERIMGMMSTGKPVRN

Sequences:

>Translated_818_residues
MQKFTVKRVAVLGAGVMGAQIAAHLVNVKVPVVLFDLPAKDNDGGGAPSSSKSSKNGIVTKAIEGLKKLKPAPLGVPEDA
ALIQPANYEEHMEQLLECDLIIEAIAERMDWKTDLYHKIAPFIAEGAIVASNTSGLSITKLSEALPESIKPRFCGIHFFN
PPRYMTLVELINTPTTGPKVLDDLEAFAVSALGKGVIRAHDTPNFIANRVGIAGMLATIKEAETFGLTYDVVDDLTGKKL
GRASSGTFRTADVVGLDTMAHVIRTLQDNLGPGKVEDPFSDIYGTPPVLAKLLESKSLGQKTGAGFYKKVGRDILRLDPE
SMEYVAAGAKANEVVGRMLKKPAGERLKLLREAEGAEARFLWAILRDQFHYAAVHLESIAETARDIDFAMRWGFGAKQGP
FELWQQAGWQQVASWIQEDIEAGKALSKAPLPDWVFKGPVADAGGVHTAEGSWSASAQKFIPRRKLPVYERQYFPEDVLG
ANAPAFETAGTTLHEDDAIRLWTLDGANGEKGDVLIASIKTKMHAISPDVAEGLAMGVDLAEKGYKGMVIWSNDEMFSAG
ADLQAMLPAFMMGGARSIEGAEAELQNVMLKLRYAAVPVVSAIRGLALGGGCEMAVYSAKRVAAMESYIGLVEVGVGLVP
GAGGLAYIARRAAENAATSTNKDILPFLTEDFTAAAMAKVGTSAIESRKIGYLLDSDVIVPNKDELLFVALNEARALFNS
GYRAPHRRPFPVVGRNGLATIKGQLVNMRDGGFISAHDFHIAGLIANVVCGGDVDAGTLVTEEYLMTLERKAFCSLLENP
KTQERIMGMMSTGKPVRN
>Mature_818_residues
MQKFTVKRVAVLGAGVMGAQIAAHLVNVKVPVVLFDLPAKDNDGGGAPSSSKSSKNGIVTKAIEGLKKLKPAPLGVPEDA
ALIQPANYEEHMEQLLECDLIIEAIAERMDWKTDLYHKIAPFIAEGAIVASNTSGLSITKLSEALPESIKPRFCGIHFFN
PPRYMTLVELINTPTTGPKVLDDLEAFAVSALGKGVIRAHDTPNFIANRVGIAGMLATIKEAETFGLTYDVVDDLTGKKL
GRASSGTFRTADVVGLDTMAHVIRTLQDNLGPGKVEDPFSDIYGTPPVLAKLLESKSLGQKTGAGFYKKVGRDILRLDPE
SMEYVAAGAKANEVVGRMLKKPAGERLKLLREAEGAEARFLWAILRDQFHYAAVHLESIAETARDIDFAMRWGFGAKQGP
FELWQQAGWQQVASWIQEDIEAGKALSKAPLPDWVFKGPVADAGGVHTAEGSWSASAQKFIPRRKLPVYERQYFPEDVLG
ANAPAFETAGTTLHEDDAIRLWTLDGANGEKGDVLIASIKTKMHAISPDVAEGLAMGVDLAEKGYKGMVIWSNDEMFSAG
ADLQAMLPAFMMGGARSIEGAEAELQNVMLKLRYAAVPVVSAIRGLALGGGCEMAVYSAKRVAAMESYIGLVEVGVGLVP
GAGGLAYIARRAAENAATSTNKDILPFLTEDFTAAAMAKVGTSAIESRKIGYLLDSDVIVPNKDELLFVALNEARALFNS
GYRAPHRRPFPVVGRNGLATIKGQLVNMRDGGFISAHDFHIAGLIANVVCGGDVDAGTLVTEEYLMTLERKAFCSLLENP
KTQERIMGMMSTGKPVRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=314, Percent_Identity=34.3949044585987, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI296179427, Length=329, Percent_Identity=33.434650455927, Blast_Score=127, Evalue=6e-29,
Organism=Homo sapiens, GI20127408, Length=312, Percent_Identity=29.1666666666667, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI68989263, Length=446, Percent_Identity=23.7668161434978, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI261878539, Length=420, Percent_Identity=23.8095238095238, Blast_Score=74, Evalue=7e-13,
Organism=Escherichia coli, GI1787661, Length=474, Percent_Identity=25.1054852320675, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790281, Length=213, Percent_Identity=29.5774647887324, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788682, Length=330, Percent_Identity=25.1515151515152, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17563036, Length=310, Percent_Identity=30.9677419354839, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17549919, Length=309, Percent_Identity=27.5080906148867, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17553560, Length=303, Percent_Identity=28.7128712871287, Blast_Score=100, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17508953, Length=306, Percent_Identity=28.7581699346405, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17508951, Length=306, Percent_Identity=28.7581699346405, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25144276, Length=306, Percent_Identity=28.7581699346405, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17558304, Length=302, Percent_Identity=29.1390728476821, Blast_Score=86, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71985923, Length=426, Percent_Identity=24.6478873239437, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24583077, Length=361, Percent_Identity=28.2548476454294, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24583079, Length=361, Percent_Identity=28.2548476454294, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI19921000, Length=365, Percent_Identity=28.4931506849315, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 87840; Mature: 87840

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKFTVKRVAVLGAGVMGAQIAAHLVNVKVPVVLFDLPAKDNDGGGAPSSSKSSKNGIVT
CCCHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHH
KAIEGLKKLKPAPLGVPEDAALIQPANYEEHMEQLLECDLIIEAIAERMDWKTDLYHKIA
HHHHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
PFIAEGAIVASNTSGLSITKLSEALPESIKPRFCGIHFFNPPRYMTLVELINTPTTGPKV
HHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCHHH
LDDLEAFAVSALGKGVIRAHDTPNFIANRVGIAGMLATIKEAETFGLTYDVVDDLTGKKL
HHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHC
GRASSGTFRTADVVGLDTMAHVIRTLQDNLGPGKVEDPFSDIYGTPPVLAKLLESKSLGQ
CCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCC
KTGAGFYKKVGRDILRLDPESMEYVAAGAKANEVVGRMLKKPAGERLKLLREAEGAEARF
CCCCHHHHHHCHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHH
LWAILRDQFHYAAVHLESIAETARDIDFAMRWGFGAKQGPFELWQQAGWQQVASWIQEDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHH
EAGKALSKAPLPDWVFKGPVADAGGVHTAEGSWSASAQKFIPRRKLPVYERQYFPEDVLG
HHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHCCCHHHHC
ANAPAFETAGTTLHEDDAIRLWTLDGANGEKGDVLIASIKTKMHAISPDVAEGLAMGVDL
CCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCEEEEEHHHHHHHCCCHHHHHHHHCCHH
AEKGYKGMVIWSNDEMFSAGADLQAMLPAFMMGGARSIEGAEAELQNVMLKLRYAAVPVV
HHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SAIRGLALGGGCEMAVYSAKRVAAMESYIGLVEVGVGLVPGAGGLAYIARRAAENAATST
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
NKDILPFLTEDFTAAAMAKVGTSAIESRKIGYLLDSDVIVPNKDELLFVALNEARALFNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEECCCCCCEEEEEEHHHHHHHHC
GYRAPHRRPFPVVGRNGLATIKGQLVNMRDGGFISAHDFHIAGLIANVVCGGDVDAGTLV
CCCCCCCCCCCCCCCCCCEEECEEEEEECCCCEEEECCHHHHHHHHHHHCCCCCCCCHHH
TEEYLMTLERKAFCSLLENPKTQERIMGMMSTGKPVRN
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQKFTVKRVAVLGAGVMGAQIAAHLVNVKVPVVLFDLPAKDNDGGGAPSSSKSSKNGIVT
CCCHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHH
KAIEGLKKLKPAPLGVPEDAALIQPANYEEHMEQLLECDLIIEAIAERMDWKTDLYHKIA
HHHHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
PFIAEGAIVASNTSGLSITKLSEALPESIKPRFCGIHFFNPPRYMTLVELINTPTTGPKV
HHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCHHH
LDDLEAFAVSALGKGVIRAHDTPNFIANRVGIAGMLATIKEAETFGLTYDVVDDLTGKKL
HHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHC
GRASSGTFRTADVVGLDTMAHVIRTLQDNLGPGKVEDPFSDIYGTPPVLAKLLESKSLGQ
CCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCC
KTGAGFYKKVGRDILRLDPESMEYVAAGAKANEVVGRMLKKPAGERLKLLREAEGAEARF
CCCCHHHHHHCHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHH
LWAILRDQFHYAAVHLESIAETARDIDFAMRWGFGAKQGPFELWQQAGWQQVASWIQEDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHH
EAGKALSKAPLPDWVFKGPVADAGGVHTAEGSWSASAQKFIPRRKLPVYERQYFPEDVLG
HHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHCCCHHHHC
ANAPAFETAGTTLHEDDAIRLWTLDGANGEKGDVLIASIKTKMHAISPDVAEGLAMGVDL
CCCCCCCCCCCEEECCCCEEEEEEECCCCCCCCEEEEEHHHHHHHCCCHHHHHHHHCCHH
AEKGYKGMVIWSNDEMFSAGADLQAMLPAFMMGGARSIEGAEAELQNVMLKLRYAAVPVV
HHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SAIRGLALGGGCEMAVYSAKRVAAMESYIGLVEVGVGLVPGAGGLAYIARRAAENAATST
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
NKDILPFLTEDFTAAAMAKVGTSAIESRKIGYLLDSDVIVPNKDELLFVALNEARALFNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEECCCCCCEEEEEEHHHHHHHHC
GYRAPHRRPFPVVGRNGLATIKGQLVNMRDGGFISAHDFHIAGLIANVVCGGDVDAGTLV
CCCCCCCCCCCCCCCCCCEEECEEEEEECCCCEEEECCHHHHHHHHHHHCCCCCCCCHHH
TEEYLMTLERKAFCSLLENPKTQERIMGMMSTGKPVRN
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]