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The map label for this gene is lrp [H]

Identifier: 91789673

GI number: 91789673

Start: 4018159

End: 4018623

Strand: Direct

Name: lrp [H]

Synonym: Bpro_3829

Alternate gene names: 91789673

Gene position: 4018159-4018623 (Clockwise)

Preceding gene: 91789668

Following gene: 91789675

Centisome position: 77.27

GC content: 58.71

Gene sequence:

>465_bases
ATGGAAATCACCCTCGACCGGATTGACCGCAAATTGCTGAAGCTGTTGCAGCAGGACGCCTCCCTGCCCAACATCGACCT
GGCCGAAAAAACCAACCTCAGCCCGCCCGCGTGCTCGCGACGCATTGCCAAGCTCAAGGAGCTGGGGCTGATCCGAAAAA
CCGTCGCGCTGGTGAACCCGCGTGCGCTGGGCTACAACGGCCTGGTCATCATTGGCGTGGTGCTGGACCGCTCGACCACC
GACTCCTTTGCCGCCTTTGAGAAAGCCGTTGCCGGCCTGACAGGCTGCCTGGAGGTGCAACTGGTGACCGGTGAATTTGA
CTACTTCGTCAAGCTGCGCATCCAGAGCATCGACTCCTTCAATGAGCTGCATGCGGCGCAGCTGATAGGTCTGCCGGGCG
TGAGGCAGATTCGCACGTTTGTGTGTTTAAAAGAAGTGTTCGAGACTACGGCGATTCCTGTTTGA

Upstream 100 bases:

>100_bases
ACTCTCAGAATGAAACCTCTTTCTGGAATCTATTTTTCAAATATTCAAGAAATTCATTTCGATTTTTATAAAATTAACGC
AATATTTAGCCAATACACCC

Downstream 100 bases:

>100_bases
GTTCAATGGAGTCGGATATCGAAAGCTATTGAATTGATAGCGGGTTGGTTTTGCTGAGGGTCGCTGGCCGGGGGTAGCCC
GGCGGCTACTCACTTTTCTT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MEITLDRIDRKLLKLLQQDASLPNIDLAEKTNLSPPACSRRIAKLKELGLIRKTVALVNPRALGYNGLVIIGVVLDRSTT
DSFAAFEKAVAGLTGCLEVQLVTGEFDYFVKLRIQSIDSFNELHAAQLIGLPGVRQIRTFVCLKEVFETTAIPV

Sequences:

>Translated_154_residues
MEITLDRIDRKLLKLLQQDASLPNIDLAEKTNLSPPACSRRIAKLKELGLIRKTVALVNPRALGYNGLVIIGVVLDRSTT
DSFAAFEKAVAGLTGCLEVQLVTGEFDYFVKLRIQSIDSFNELHAAQLIGLPGVRQIRTFVCLKEVFETTAIPV
>Mature_154_residues
MEITLDRIDRKLLKLLQQDASLPNIDLAEKTNLSPPACSRRIAKLKELGLIRKTVALVNPRALGYNGLVIIGVVLDRSTT
DSFAAFEKAVAGLTGCLEVQLVTGEFDYFVKLRIQSIDSFNELHAAQLIGLPGVRQIRTFVCLKEVFETTAIPV

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=148, Percent_Identity=37.1621621621622, Blast_Score=112, Evalue=9e-27,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=27.3333333333333, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1790182, Length=149, Percent_Identity=26.8456375838926, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 16980; Mature: 16980

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEITLDRIDRKLLKLLQQDASLPNIDLAEKTNLSPPACSRRIAKLKELGLIRKTVALVNP
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
RALGYNGLVIIGVVLDRSTTDSFAAFEKAVAGLTGCLEVQLVTGEFDYFVKLRIQSIDSF
CCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEEEEHHHCCH
NELHAAQLIGLPGVRQIRTFVCLKEVFETTAIPV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEITLDRIDRKLLKLLQQDASLPNIDLAEKTNLSPPACSRRIAKLKELGLIRKTVALVNP
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
RALGYNGLVIIGVVLDRSTTDSFAAFEKAVAGLTGCLEVQLVTGEFDYFVKLRIQSIDSF
CCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEEEEHHHCCH
NELHAAQLIGLPGVRQIRTFVCLKEVFETTAIPV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]