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The map label for this gene is rnc [H]

Identifier: 91789485

GI number: 91789485

Start: 3836649

End: 3837350

Strand: Reverse

Name: rnc [H]

Synonym: Bpro_3635

Alternate gene names: 91789485

Gene position: 3837350-3836649 (Counterclockwise)

Preceding gene: 91789486

Following gene: 91789484

Centisome position: 73.79

GC content: 62.11

Gene sequence:

>702_bases
GTGAGAGCCAGCGCCACCTCAAGCCCAGACCTGCTGGCACTGCAAAAACGCCTGCAGCACGAGTTTTCCAATCCGAAACT
GCTGGCGCAGGCGCTCACGCATCGCAGTTTTTCCGCCGACCACAATGAGCGGATCGAGTTTCTGGGCGACTCCGTATTGA
ACCTCGCGGTGGCCGGCCTGCTGTATGAGCAACTGAGCGAGTTGCCTGAGGGCGATCTGTCCCGCGTGCGTGCCAACCTT
GTCAAGCAGGACACCCTGCACAAGCTGGCGGTGACGCTGGGCCTGCCCGAGATGTTGCGGCTCGGCGAGGGCGAGGCCCG
GTCTGGCGGGCAGAAACGGCCCTCCATCCTGGCGGATGCGCTGGAGGCCGTGATAGGCGCGGTCTATCTGGATGCGGGCT
TCGACAAGGCCGACCAACTGGTGCGACGCCTGTTCAGGAACGTTGAAATCAACCCGCAGATGCAGGCCATTGGCAAGGAC
CCGAAAACCGAATTGCAGGAGTGGTTGCAAGGGCGCAAAATGAACCTGCCAATTTATCGGGTGGTCGGCACGATGGGTGC
GGCCCACAAGCAGACATTCGATGTGGAGTGCGAAATCACCGAATACGGACGGGCCGAGCGAGGGATCGGTGGTTCACGCC
GGGCGGGTGAACAGGCGGCGGCGGCCGCCATGCTGATCTACCTCAAAACCCTGGATTCCTGA

Upstream 100 bases:

>100_bases
AGAGGGCGACAAGACCGTGGTGGCTTTCGCCTATACCCGTGAAATCCACATGGCAGGTCCCGCTTACCTGCTGCTGAAGT
ACAACGGCCGATCCAAATAA

Downstream 100 bases:

>100_bases
CTCGGCGTCGCAACCGCGCCCCGCCCAACACCATTTGAGAGACCATGAGTACAGGTAAAAAAGAGCCGAAGAAGCCGGCG
AATATATCGCTTGAATTGCC

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRASATSSPDLLALQKRLQHEFSNPKLLAQALTHRSFSADHNERIEFLGDSVLNLAVAGLLYEQLSELPEGDLSRVRANL
VKQDTLHKLAVTLGLPEMLRLGEGEARSGGQKRPSILADALEAVIGAVYLDAGFDKADQLVRRLFRNVEINPQMQAIGKD
PKTELQEWLQGRKMNLPIYRVVGTMGAAHKQTFDVECEITEYGRAERGIGGSRRAGEQAAAAAMLIYLKTLDS

Sequences:

>Translated_233_residues
MRASATSSPDLLALQKRLQHEFSNPKLLAQALTHRSFSADHNERIEFLGDSVLNLAVAGLLYEQLSELPEGDLSRVRANL
VKQDTLHKLAVTLGLPEMLRLGEGEARSGGQKRPSILADALEAVIGAVYLDAGFDKADQLVRRLFRNVEINPQMQAIGKD
PKTELQEWLQGRKMNLPIYRVVGTMGAAHKQTFDVECEITEYGRAERGIGGSRRAGEQAAAAAMLIYLKTLDS
>Mature_233_residues
MRASATSSPDLLALQKRLQHEFSNPKLLAQALTHRSFSADHNERIEFLGDSVLNLAVAGLLYEQLSELPEGDLSRVRANL
VKQDTLHKLAVTLGLPEMLRLGEGEARSGGQKRPSILADALEAVIGAVYLDAGFDKADQLVRRLFRNVEINPQMQAIGKD
PKTELQEWLQGRKMNLPIYRVVGTMGAAHKQTFDVECEITEYGRAERGIGGSRRAGEQAAAAAMLIYLKTLDS

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=222, Percent_Identity=30.6306306306306, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI155030234, Length=222, Percent_Identity=30.6306306306306, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1788920, Length=203, Percent_Identity=48.2758620689655, Blast_Score=183, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI17506883, Length=203, Percent_Identity=31.0344827586207, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193202651, Length=203, Percent_Identity=31.0344827586207, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17137682, Length=224, Percent_Identity=31.6964285714286, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 25635; Mature: 25635

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50137 DS_RBD ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASATSSPDLLALQKRLQHEFSNPKLLAQALTHRSFSADHNERIEFLGDSVLNLAVAGL
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LYEQLSELPEGDLSRVRANLVKQDTLHKLAVTLGLPEMLRLGEGEARSGGQKRPSILADA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHH
LEAVIGAVYLDAGFDKADQLVRRLFRNVEINPQMQAIGKDPKTELQEWLQGRKMNLPIYR
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCHHHH
VVGTMGAAHKQTFDVECEITEYGRAERGIGGSRRAGEQAAAAAMLIYLKTLDS
HHHHHCHHHCCCCCEEEEHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRASATSSPDLLALQKRLQHEFSNPKLLAQALTHRSFSADHNERIEFLGDSVLNLAVAGL
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LYEQLSELPEGDLSRVRANLVKQDTLHKLAVTLGLPEMLRLGEGEARSGGQKRPSILADA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHH
LEAVIGAVYLDAGFDKADQLVRRLFRNVEINPQMQAIGKDPKTELQEWLQGRKMNLPIYR
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCHHHH
VVGTMGAAHKQTFDVECEITEYGRAERGIGGSRRAGEQAAAAAMLIYLKTLDS
HHHHHCHHHCCCCCEEEEHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA