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The map label for this gene is sdhB [H]

Identifier: 91789454

GI number: 91789454

Start: 3805192

End: 3805896

Strand: Direct

Name: sdhB [H]

Synonym: Bpro_3603

Alternate gene names: 91789454

Gene position: 3805192-3805896 (Clockwise)

Preceding gene: 91789453

Following gene: 91789455

Centisome position: 73.17

GC content: 61.42

Gene sequence:

>705_bases
ATGTCAAAACGTACCTTCCAGATCTACCGCTACGACCCGGACACCGACGCCAAGCCCTACATGCAGACCATCGAGGTGGA
ACTCGACGGCAGCGAACGCATGCTGCTGGACGCCCTGATGAAGCTCAAGGCCCAGGATCCGAGCATCAGCTTTCGCCGCT
CCTGCCGCGAAGGCGTTTGCGGCTCCGACGCGATGAACATCAACGGCAAGAACGGCCTGGCCTGCCTGACCAACATGCGC
ACGCTGCCCGGCACCATTGTCCTGAAGCCGCTGCCCGGCCTGCCCGTGGTGCGCGACCTGATTGTCGACATGACGCAGTT
CTTCAAGCAGTACAACTCGATCAAGCCCTACCTGATCAACGATAACGTACCGCCCGAAAAAGAGCGCCTGCAAAGCCCCG
AGGAGCGCGACGAGCTCAACGGCCTTTACGAGTGCATCCTGTGCGCCAGCTGCTCCACCTCCTGCCCCAGCTTCTGGTGG
AATCCCGACAAGTTTGTCGGTCCTGCCGGCCTGCTGCAGGCTTACCGTTTCATTGCCGACAGCCGCGATGAAGCCACGGC
CGAGCGGCTCGACAACCTGGAAGACCCGTACCGGCTGTTCCGCTGCCACACCATCATGAACTGCGTCGATGTCTGCCCCA
AGGGCCTGAACCCGACCCGGGCCATTGGCAAGATCAAGGAAATGATGGTCCTGCGCGCAGTCTGA

Upstream 100 bases:

>100_bases
TGAAGCCGCTGACGGTTGAGTCCGTGCCGCTCAAAGTGCGCAGCTTCTAAGCGCAAGCCAAGCGAACCAGTCAAGCCAAC
AAGACCGCGAGAAACGCCCC

Downstream 100 bases:

>100_bases
TCAATTATTTGGCATGATTGGCATGGAAGCCCCTGACGTTTTGCTCGATGAGCGCTCCCTGAGCAAGCTCAAGTGGCGCT
GCCGCCGGGGCCTGCTGGAA

Product: succinate dehydrogenase subunit B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSKRTFQIYRYDPDTDAKPYMQTIEVELDGSERMLLDALMKLKAQDPSISFRRSCREGVCGSDAMNINGKNGLACLTNMR
TLPGTIVLKPLPGLPVVRDLIVDMTQFFKQYNSIKPYLINDNVPPEKERLQSPEERDELNGLYECILCASCSTSCPSFWW
NPDKFVGPAGLLQAYRFIADSRDEATAERLDNLEDPYRLFRCHTIMNCVDVCPKGLNPTRAIGKIKEMMVLRAV

Sequences:

>Translated_234_residues
MSKRTFQIYRYDPDTDAKPYMQTIEVELDGSERMLLDALMKLKAQDPSISFRRSCREGVCGSDAMNINGKNGLACLTNMR
TLPGTIVLKPLPGLPVVRDLIVDMTQFFKQYNSIKPYLINDNVPPEKERLQSPEERDELNGLYECILCASCSTSCPSFWW
NPDKFVGPAGLLQAYRFIADSRDEATAERLDNLEDPYRLFRCHTIMNCVDVCPKGLNPTRAIGKIKEMMVLRAV
>Mature_233_residues
SKRTFQIYRYDPDTDAKPYMQTIEVELDGSERMLLDALMKLKAQDPSISFRRSCREGVCGSDAMNINGKNGLACLTNMRT
LPGTIVLKPLPGLPVVRDLIVDMTQFFKQYNSIKPYLINDNVPPEKERLQSPEERDELNGLYECILCASCSTSCPSFWWN
PDKFVGPAGLLQAYRFIADSRDEATAERLDNLEDPYRLFRCHTIMNCVDVCPKGLNPTRAIGKIKEMMVLRAV

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=232, Percent_Identity=56.4655172413793, Blast_Score=271, Evalue=5e-73,
Organism=Escherichia coli, GI1786943, Length=232, Percent_Identity=67.2413793103448, Blast_Score=328, Evalue=2e-91,
Organism=Escherichia coli, GI1790596, Length=230, Percent_Identity=35.6521739130435, Blast_Score=150, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17533915, Length=233, Percent_Identity=52.7896995708155, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6322987, Length=232, Percent_Identity=51.7241379310345, Blast_Score=254, Evalue=1e-68,
Organism=Drosophila melanogaster, GI17137106, Length=233, Percent_Identity=55.793991416309, Blast_Score=273, Evalue=8e-74,
Organism=Drosophila melanogaster, GI24643156, Length=232, Percent_Identity=54.3103448275862, Blast_Score=262, Evalue=1e-70,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26586; Mature: 26455

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRTFQIYRYDPDTDAKPYMQTIEVELDGSERMLLDALMKLKAQDPSISFRRSCREGVC
CCCCEEEEEEECCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
GSDAMNINGKNGLACLTNMRTLPGTIVLKPLPGLPVVRDLIVDMTQFFKQYNSIKPYLIN
CCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEC
DNVPPEKERLQSPEERDELNGLYECILCASCSTSCPSFWWNPDKFVGPAGLLQAYRFIAD
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
SRDEATAERLDNLEDPYRLFRCHTIMNCVDVCPKGLNPTRAIGKIKEMMVLRAV
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKRTFQIYRYDPDTDAKPYMQTIEVELDGSERMLLDALMKLKAQDPSISFRRSCREGVC
CCCEEEEEEECCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
GSDAMNINGKNGLACLTNMRTLPGTIVLKPLPGLPVVRDLIVDMTQFFKQYNSIKPYLIN
CCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEC
DNVPPEKERLQSPEERDELNGLYECILCASCSTSCPSFWWNPDKFVGPAGLLQAYRFIAD
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
SRDEATAERLDNLEDPYRLFRCHTIMNCVDVCPKGLNPTRAIGKIKEMMVLRAV
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]