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The map label for this gene is gbpR [H]

Identifier: 91789368

GI number: 91789368

Start: 3715270

End: 3716235

Strand: Reverse

Name: gbpR [H]

Synonym: Bpro_3514

Alternate gene names: 91789368

Gene position: 3716235-3715270 (Counterclockwise)

Preceding gene: 91789371

Following gene: 91789350

Centisome position: 71.46

GC content: 67.91

Gene sequence:

>966_bases
ATGGACCCGATCACCGATAGCCCACCCGTTCCCGCCAACCTGTTTCGCCGGCTGCGCATCAAGAGCCGGCAAATCATGCT
GCTGAACGCCCTGGATGAGCACCGCAACCTCCGGCGGGCGGCGGCGGCCATTCATACCACCCAGCCCGCTGCCACGGCGC
TGCTGCAGCAGCTCGAAGAAGGCCTGGGCGTGGCGCTGTTTGAGCGGCACTCGCGCGGCATGGAGCCCACGGTGTACGGT
GAGGTGATGATCCGCTACGCGCGCGGCGTGCTGCACGATTTCGAGTACGCCGGTGACGAAATGGCGGCCCTGGCTGCAGG
GGCGGCCGGGCTGGTGCGCATCGGCAGCGTCATGGGCGCCACGCCAGTCCTGCTCACCCAGGGCCTGGCGCGCTTCAAGG
CCGGCCACCCGCGCGTGCGCGTTTCCCTGCAGGTCGACACCAGCGACCTGCTGATGCCGGCGCTGCTGCGCGGTGACCTC
GATGTGGTGCTGGGGCGCCTGCCGGACCAGTTTTATGACGAGGATCTGGAGATCGAGCAGTTGGAGGGCGAACCGATGAG
CGTGGTGGCGCGGCCGGGCCATCCGCTGCTTGACCTCGCCAAGGTGACGCTGGCCGACCTGGTCGCGCAAACCTGGATCC
TGCATCCGCTGGGCAGCCCGATGCGGCGCCGCGTCGAGCAGGCGCTGCAGCACGCCGGCCTGGCGGCGCCCCCCGACATC
GTCGAGACCTCGTCCATCCTCGCAACCACCTCGCTGCTGGAGGCCAGCGACATGATCTCGGTGGTTCCGCTGGACGTGGC
ACAGCACTATGCGAACTATGGGCTGGTCGCGATCTTGCCGGTGGAACTGCCGATGTCCATGGCCAAGCTGGGCATCATCA
CGCGCAGAAAAAAAGACCTGTCGCCCGCGGTGAAGGGCTTTCTGCACGCGCTGCGCGACAGCATCCTGCAGCGGCAGGCT
GCCTAG

Upstream 100 bases:

>100_bases
TGTGGTTGAAATGGTTGAAATGGATGGCACAGCTTATAAAGATTGGCGATATCAATCCAATCTTATTTTGGTATATTGCG
ATACTATTTTTGATATCACA

Downstream 100 bases:

>100_bases
GTGAAATTTTCGTGATCATGTCGCAGATGGGGAGAGCAATTGCATAGTCATTCCGGTGGATTCTGCGCAGGCACGACCGC
CCCCAGCCACTCGCGTTCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MDPITDSPPVPANLFRRLRIKSRQIMLLNALDEHRNLRRAAAAIHTTQPAATALLQQLEEGLGVALFERHSRGMEPTVYG
EVMIRYARGVLHDFEYAGDEMAALAAGAAGLVRIGSVMGATPVLLTQGLARFKAGHPRVRVSLQVDTSDLLMPALLRGDL
DVVLGRLPDQFYDEDLEIEQLEGEPMSVVARPGHPLLDLAKVTLADLVAQTWILHPLGSPMRRRVEQALQHAGLAAPPDI
VETSSILATTSLLEASDMISVVPLDVAQHYANYGLVAILPVELPMSMAKLGIITRRKKDLSPAVKGFLHALRDSILQRQA
A

Sequences:

>Translated_321_residues
MDPITDSPPVPANLFRRLRIKSRQIMLLNALDEHRNLRRAAAAIHTTQPAATALLQQLEEGLGVALFERHSRGMEPTVYG
EVMIRYARGVLHDFEYAGDEMAALAAGAAGLVRIGSVMGATPVLLTQGLARFKAGHPRVRVSLQVDTSDLLMPALLRGDL
DVVLGRLPDQFYDEDLEIEQLEGEPMSVVARPGHPLLDLAKVTLADLVAQTWILHPLGSPMRRRVEQALQHAGLAAPPDI
VETSSILATTSLLEASDMISVVPLDVAQHYANYGLVAILPVELPMSMAKLGIITRRKKDLSPAVKGFLHALRDSILQRQA
A
>Mature_321_residues
MDPITDSPPVPANLFRRLRIKSRQIMLLNALDEHRNLRRAAAAIHTTQPAATALLQQLEEGLGVALFERHSRGMEPTVYG
EVMIRYARGVLHDFEYAGDEMAALAAGAAGLVRIGSVMGATPVLLTQGLARFKAGHPRVRVSLQVDTSDLLMPALLRGDL
DVVLGRLPDQFYDEDLEIEQLEGEPMSVVARPGHPLLDLAKVTLADLVAQTWILHPLGSPMRRRVEQALQHAGLAAPPDI
VETSSILATTSLLEASDMISVVPLDVAQHYANYGLVAILPVELPMSMAKLGIITRRKKDLSPAVKGFLHALRDSILQRQA
A

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=295, Percent_Identity=28.4745762711864, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081904, Length=303, Percent_Identity=26.4026402640264, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787601, Length=296, Percent_Identity=25.3378378378378, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1789506, Length=285, Percent_Identity=22.1052631578947, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693105, Length=278, Percent_Identity=26.2589928057554, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790399, Length=304, Percent_Identity=25.9868421052632, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790262, Length=294, Percent_Identity=24.8299319727891, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787806, Length=295, Percent_Identity=25.0847457627119, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788887, Length=297, Percent_Identity=26.5993265993266, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=303, Percent_Identity=24.0924092409241, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787589, Length=122, Percent_Identity=29.5081967213115, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34943; Mature: 34943

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPITDSPPVPANLFRRLRIKSRQIMLLNALDEHRNLRRAAAAIHTTQPAATALLQQLEE
CCCCCCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GLGVALFERHSRGMEPTVYGEVMIRYARGVLHDFEYAGDEMAALAAGAAGLVRIGSVMGA
CCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHCC
TPVLLTQGLARFKAGHPRVRVSLQVDTSDLLMPALLRGDLDVVLGRLPDQFYDEDLEIEQ
CHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHCCHHHHHHHCCHHHCCCCCCHHH
LEGEPMSVVARPGHPLLDLAKVTLADLVAQTWILHPLGSPMRRRVEQALQHAGLAAPPDI
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCH
VETSSILATTSLLEASDMISVVPLDVAQHYANYGLVAILPVELPMSMAKLGIITRRKKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCHHHC
SPAVKGFLHALRDSILQRQAA
CHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDPITDSPPVPANLFRRLRIKSRQIMLLNALDEHRNLRRAAAAIHTTQPAATALLQQLEE
CCCCCCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GLGVALFERHSRGMEPTVYGEVMIRYARGVLHDFEYAGDEMAALAAGAAGLVRIGSVMGA
CCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHCC
TPVLLTQGLARFKAGHPRVRVSLQVDTSDLLMPALLRGDLDVVLGRLPDQFYDEDLEIEQ
CHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHCCHHHHHHHCCHHHCCCCCCHHH
LEGEPMSVVARPGHPLLDLAKVTLADLVAQTWILHPLGSPMRRRVEQALQHAGLAAPPDI
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCH
VETSSILATTSLLEASDMISVVPLDVAQHYANYGLVAILPVELPMSMAKLGIITRRKKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCHHHC
SPAVKGFLHALRDSILQRQAA
CHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]