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The map label for this gene is ahpC [H]

Identifier: 91788904

GI number: 91788904

Start: 3209971

End: 3210543

Strand: Direct

Name: ahpC [H]

Synonym: Bpro_3044

Alternate gene names: 91788904

Gene position: 3209971-3210543 (Clockwise)

Preceding gene: 91788903

Following gene: 91788905

Centisome position: 61.73

GC content: 61.61

Gene sequence:

>573_bases
ATGTCTCTGATCAACACCGAAATCATTCCCTTCAAGGCCACCGCGTATCACAACGGCAAGTTCGTTCCTGTCAGCAACGA
GAACTTCATGGGCCATTGGTCCGTCGTGGTGTTCTACCCGGCCGACTTCACCTTTGTCTGCCCGACCGAACTGGGCGACC
TGGCCGACCACTACGCAGAATTCCAGAAGCTGGGCGTCCAGATTTACGGCGTGTCGACCGACACCCACTTCACCCACAAG
GCCTGGCACGACACCTCCGACACCATCCGCAAGGTCCAGTACCCGCTGATCGGCGACCCCAGCCAGCAGCTGTCCCGCGC
CTTCCAGGTGCTGATCGAAGAAGGTGAAGACGCAGGCCTGGCCTATCGCGGCACCTTCGTGATTGACCCGGCAGGCAAGA
TCAAGACCATCGAAGTGCACGACAACGGCATCGGCCGTGACGCTGCCGAGCTGCTGCGCCGCGTGAAGGCTGCCCAGTAC
GTGGCCGCCCACCCCGGTGAAGTCTGCCCCGCCAAGTGGACGGAAGGCGCCGAAACGCTGAAGCCTTCGCTCGACCTGGT
CGGCAAGATCTAA

Upstream 100 bases:

>100_bases
ATAAATAGTAAATACCTATCAAAGTCAATAAATTAAAAGACATATACTATCAATTCGCAAGCACTCAAGTATTTTTTTAA
CCAAGCCATAGAAAGCAAAA

Downstream 100 bases:

>100_bases
GCCCAGCCTGTTTGCGCCAAGCCCGGGCGCGCCAGCTCCCGGGCTTTTTTATTCCCCCATGCATTCGAAAAGTGAGTTCC
CCATGCTCGACGCCAGCACC

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSLINTEIIPFKATAYHNGKFVPVSNENFMGHWSVVVFYPADFTFVCPTELGDLADHYAEFQKLGVQIYGVSTDTHFTHK
AWHDTSDTIRKVQYPLIGDPSQQLSRAFQVLIEEGEDAGLAYRGTFVIDPAGKIKTIEVHDNGIGRDAAELLRRVKAAQY
VAAHPGEVCPAKWTEGAETLKPSLDLVGKI

Sequences:

>Translated_190_residues
MSLINTEIIPFKATAYHNGKFVPVSNENFMGHWSVVVFYPADFTFVCPTELGDLADHYAEFQKLGVQIYGVSTDTHFTHK
AWHDTSDTIRKVQYPLIGDPSQQLSRAFQVLIEEGEDAGLAYRGTFVIDPAGKIKTIEVHDNGIGRDAAELLRRVKAAQY
VAAHPGEVCPAKWTEGAETLKPSLDLVGKI
>Mature_189_residues
SLINTEIIPFKATAYHNGKFVPVSNENFMGHWSVVVFYPADFTFVCPTELGDLADHYAEFQKLGVQIYGVSTDTHFTHKA
WHDTSDTIRKVQYPLIGDPSQQLSRAFQVLIEEGEDAGLAYRGTFVIDPAGKIKTIEVHDNGIGRDAAELLRRVKAAQYV
AAHPGEVCPAKWTEGAETLKPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=176, Percent_Identity=46.0227272727273, Blast_Score=154, Evalue=3e-38,
Organism=Homo sapiens, GI5802974, Length=176, Percent_Identity=46.0227272727273, Blast_Score=154, Evalue=3e-38,
Organism=Homo sapiens, GI32189392, Length=178, Percent_Identity=43.8202247191011, Blast_Score=150, Evalue=8e-37,
Organism=Homo sapiens, GI4505591, Length=178, Percent_Identity=41.5730337078652, Blast_Score=143, Evalue=7e-35,
Organism=Homo sapiens, GI32455266, Length=178, Percent_Identity=41.5730337078652, Blast_Score=143, Evalue=7e-35,
Organism=Homo sapiens, GI32455264, Length=178, Percent_Identity=41.5730337078652, Blast_Score=143, Evalue=7e-35,
Organism=Homo sapiens, GI5453549, Length=183, Percent_Identity=38.2513661202186, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI33188454, Length=74, Percent_Identity=47.2972972972973, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI4758638, Length=163, Percent_Identity=29.4478527607362, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786822, Length=190, Percent_Identity=65.7894736842105, Blast_Score=268, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=41.2429378531073, Blast_Score=147, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI32565831, Length=177, Percent_Identity=41.2429378531073, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI193204376, Length=177, Percent_Identity=41.2429378531073, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25153706, Length=169, Percent_Identity=28.4023668639053, Blast_Score=73, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6320661, Length=178, Percent_Identity=38.7640449438202, Blast_Score=128, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6323613, Length=178, Percent_Identity=38.7640449438202, Blast_Score=126, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319407, Length=164, Percent_Identity=32.3170731707317, Blast_Score=85, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24656348, Length=176, Percent_Identity=41.4772727272727, Blast_Score=143, Evalue=5e-35,
Organism=Drosophila melanogaster, GI17864676, Length=176, Percent_Identity=41.4772727272727, Blast_Score=143, Evalue=5e-35,
Organism=Drosophila melanogaster, GI21357347, Length=194, Percent_Identity=38.659793814433, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI17738015, Length=180, Percent_Identity=37.2222222222222, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI17157991, Length=173, Percent_Identity=40.4624277456647, Blast_Score=136, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24641739, Length=173, Percent_Identity=40.4624277456647, Blast_Score=136, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24581278, Length=155, Percent_Identity=31.6129032258064, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17975518, Length=167, Percent_Identity=30.5389221556886, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24652434, Length=167, Percent_Identity=30.5389221556886, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24652436, Length=167, Percent_Identity=30.5389221556886, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21034; Mature: 20903

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINTEIIPFKATAYHNGKFVPVSNENFMGHWSVVVFYPADFTFVCPTELGDLADHYAE
CCCCCCEEEEEEEEEEECCEEEEECCCCCCEEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVQIYGVSTDTHFTHKAWHDTSDTIRKVQYPLIGDPSQQLSRAFQVLIEEGEDAGL
HHHCCEEEEEECCCCCEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCE
AYRGTFVIDPAGKIKTIEVHDNGIGRDAAELLRRVKAAQYVAAHPGEVCPAKWTEGAETL
EEECEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
KPSLDLVGKI
CCCHHHHCCC
>Mature Secondary Structure 
SLINTEIIPFKATAYHNGKFVPVSNENFMGHWSVVVFYPADFTFVCPTELGDLADHYAE
CCCCCEEEEEEEEEEECCEEEEECCCCCCEEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVQIYGVSTDTHFTHKAWHDTSDTIRKVQYPLIGDPSQQLSRAFQVLIEEGEDAGL
HHHCCEEEEEECCCCCEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCE
AYRGTFVIDPAGKIKTIEVHDNGIGRDAAELLRRVKAAQYVAAHPGEVCPAKWTEGAETL
EEECEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
KPSLDLVGKI
CCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]