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The map label for this gene is paaG [C]

Identifier: 91788818

GI number: 91788818

Start: 3119453

End: 3120232

Strand: Direct

Name: paaG [C]

Synonym: Bpro_2958

Alternate gene names: 91788818

Gene position: 3119453-3120232 (Clockwise)

Preceding gene: 91788817

Following gene: 91788819

Centisome position: 59.99

GC content: 65.0

Gene sequence:

>780_bases
ATGGCAGGCGCAATCAAAAGTACCAGTGAGGGCCAGACCCTCATCCTGACGCTGAGCAACCCCGAGTTCCGCAATGCGCT
GGGGCCGGAGATTTACGCCGCAGGCATTGAGGCCCTCAATGCCGCCGAGAACAACCCCGAAATCCGCAGCGTGGTGATCA
CCGGCGAGGGCGCGGTGTTTTGCGCGGGCGGCAACCTGCAGCGCCTGCAAGCCAACCGGCGTGAGGCACCCGAGGTCCAG
GCCCAGAGCATCGAAGGGCTGCACAACTGGATTGACTCGATACGCACTTATCCCAAACCCGTGATCGCCGCAGTCGAAGG
TGCGGCGGCCGGGGCCGGCTTTTCGCTGGCACTGGCCTGCGACTTTGTCGTCGCCGCAAGCAACGCTGTGTTTGTGATGT
CCTACAGCACGGTCGGGCTGTCCCCCGACGGTGGCGGCAGCTGGAGCCTGGCGCGCTCTCTGCCACGCGCCCTTGCCAGC
GAGCTGCTCATGGGCGGCGAACGCATCAGCGCCCAGCGCCTGCATGACTTGGGCCTGGTGAACAAGGTCGCATCCGCGGG
TGATGCCCTGAGTGAAGCGCTCAGGATGGCCGGGCAACTCAATGCGCGCGCGCCCAATGCGCTGGCCAGCATCAAGGAGC
TCATCAATGAGGCGTCCTCAAACACCCTGAGCCAGCAACTGGCCTGCGAGCGCGACCATTTCGTGCGCAACCTGCACCAC
AGCAATGGCGGCGAGGGCATCGCCGCATTCCTGGGAAAGCGCACACCGCAGTACCGCTGA

Upstream 100 bases:

>100_bases
GGCCTGGCGAAGCCAGTTCCGCGGCCCCCATTGGTAAGTGGACTTGTACGGGGACTCGGTCCCTGCCTATTTCTCATTTC
GATGCATTGGAAAAACTGAC

Downstream 100 bases:

>100_bases
GGAGCCGCCGGTTTTGCCCCGCCAACCGGTGGCGGCAATGCATGGCCAGACGGATGGCAAGGCGCAGTGGCAGAACTTGC
TTTGCATGGGAAGCGATACC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MAGAIKSTSEGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVFCAGGNLQRLQANRREAPEVQ
AQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALACDFVVAASNAVFVMSYSTVGLSPDGGGSWSLARSLPRALAS
ELLMGGERISAQRLHDLGLVNKVASAGDALSEALRMAGQLNARAPNALASIKELINEASSNTLSQQLACERDHFVRNLHH
SNGGEGIAAFLGKRTPQYR

Sequences:

>Translated_259_residues
MAGAIKSTSEGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVFCAGGNLQRLQANRREAPEVQ
AQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALACDFVVAASNAVFVMSYSTVGLSPDGGGSWSLARSLPRALAS
ELLMGGERISAQRLHDLGLVNKVASAGDALSEALRMAGQLNARAPNALASIKELINEASSNTLSQQLACERDHFVRNLHH
SNGGEGIAAFLGKRTPQYR
>Mature_258_residues
AGAIKSTSEGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVFCAGGNLQRLQANRREAPEVQA
QSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALACDFVVAASNAVFVMSYSTVGLSPDGGGSWSLARSLPRALASE
LLMGGERISAQRLHDLGLVNKVASAGDALSEALRMAGQLNARAPNALASIKELINEASSNTLSQQLACERDHFVRNLHHS
NGGEGIAAFLGKRTPQYR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=245, Percent_Identity=30.6122448979592, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI31542718, Length=244, Percent_Identity=31.5573770491803, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI25453481, Length=210, Percent_Identity=29.0476190476191, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI51538573, Length=210, Percent_Identity=29.0476190476191, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4757966, Length=210, Percent_Identity=29.0476190476191, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI51538581, Length=210, Percent_Identity=29.0476190476191, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4757968, Length=209, Percent_Identity=28.7081339712919, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI49355787, Length=209, Percent_Identity=28.7081339712919, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI221136756, Length=253, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI221136753, Length=253, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI116235487, Length=179, Percent_Identity=34.0782122905028, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI221307494, Length=210, Percent_Identity=30.4761904761905, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4502327, Length=251, Percent_Identity=29.0836653386454, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI45643119, Length=221, Percent_Identity=28.5067873303167, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI260275230, Length=221, Percent_Identity=28.5067873303167, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI150378541, Length=260, Percent_Identity=29.2307692307692, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI260274832, Length=221, Percent_Identity=28.5067873303167, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI70995211, Length=216, Percent_Identity=28.7037037037037, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI37594469, Length=176, Percent_Identity=30.6818181818182, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI68989263, Length=187, Percent_Identity=30.4812834224599, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI37594471, Length=176, Percent_Identity=30.6818181818182, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI157694516, Length=221, Percent_Identity=23.9819004524887, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI213417737, Length=221, Percent_Identity=23.9819004524887, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=38.4615384615385, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787659, Length=252, Percent_Identity=35.3174603174603, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=34.469696969697, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788597, Length=245, Percent_Identity=29.7959183673469, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI87082183, Length=219, Percent_Identity=28.310502283105, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788682, Length=190, Percent_Identity=30.5263157894737, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=31.9672131147541, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17554946, Length=257, Percent_Identity=29.9610894941634, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17535521, Length=250, Percent_Identity=26.8, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17540714, Length=236, Percent_Identity=30.9322033898305, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17549921, Length=215, Percent_Identity=26.9767441860465, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=201, Percent_Identity=27.8606965174129, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17540306, Length=251, Percent_Identity=28.2868525896414, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=249, Percent_Identity=23.2931726907631, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=225, Percent_Identity=26.2222222222222, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=190, Percent_Identity=25.7894736842105, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=192, Percent_Identity=26.5625, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=252, Percent_Identity=31.3492063492063, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24653477, Length=252, Percent_Identity=31.3492063492063, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI19922422, Length=244, Percent_Identity=27.4590163934426, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24653139, Length=205, Percent_Identity=31.7073170731707, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24654903, Length=245, Percent_Identity=24.4897959183673, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920382, Length=207, Percent_Identity=27.536231884058, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24667722, Length=170, Percent_Identity=27.0588235294118, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650670, Length=187, Percent_Identity=28.8770053475936, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21357171, Length=190, Percent_Identity=26.8421052631579, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27119; Mature: 26988

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGAIKSTSEGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVF
CCCCCCCCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEE
CAGGNLQRLQANRREAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALAC
EECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHH
DFVVAASNAVFVMSYSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGLV
HHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
NKVASAGDALSEALRMAGQLNARAPNALASIKELINEASSNTLSQQLACERDHFVRNLHH
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SNGGEGIAAFLGKRTPQYR
CCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
AGAIKSTSEGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVF
CCCCCCCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEE
CAGGNLQRLQANRREAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALAC
EECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHH
DFVVAASNAVFVMSYSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGLV
HHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
NKVASAGDALSEALRMAGQLNARAPNALASIKELINEASSNTLSQQLACERDHFVRNLHH
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SNGGEGIAAFLGKRTPQYR
CCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA