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The map label for this gene is ntcA [H]

Identifier: 91788819

GI number: 91788819

Start: 3120528

End: 3121253

Strand: Direct

Name: ntcA [H]

Synonym: Bpro_2959

Alternate gene names: 91788819

Gene position: 3120528-3121253 (Clockwise)

Preceding gene: 91788818

Following gene: 91788820

Centisome position: 60.01

GC content: 62.81

Gene sequence:

>726_bases
ATGGACGATCCTATTCTTACGATAGATGAAAGAGCGGCCATCAACAGTGGTCGCTGGTTTTCATCACTGTCCCCGTCCCT
GAGGCACGACATCCTGCGATGCGCTTACGTCAAACGCTACAAAGACGGCGAATTGATTGCCGCCCGCGGCGATCCGCCGG
AAGAATGGATTGCCTGCGCGAAGGGAGCCGTGCGCGTAAGCTCCACCTCCCTCTCGGGCAAGCAGATCACCCTGACCTAT
GTCGAGCCAGGCATCTGGTTTGGCGACGTGGCGATTTTCGACGGCGACCGCCGCACGCACGACGCGTATGCGCACGGCGA
CACCACGATCCTGTGCGTGGCCAAGGCCGATTTCAGAAAAATTCTGGCAGCCCATGTGGAGCTCTACGAGGCCATGCTGC
GGCTCCATGCACGGCGCCTGCGTCAGCTCTTCGGCCTGGTGGAAGACCTCAACACCCTGCCCCTGCGCGCGCGCCTGGCC
AAGCAGCTGTTGCACCTCGTTCGCTGCTACGGCGTGCCCAGCCTGGCCGACGGCCAGGAGATACGCATCGGCCTGCAGCT
GGCCCAGGAGGAGTTGGCCCAGTTGCTGGGTGCCTCCCGCCAGCGCGTCAACCAGGAGCTCAAGTCCATGGAGCGCGAGG
AGGCGATCCGCATCGAGCCAGGGGGCCTGGTGGTGCGAAACCGCGAAGCCCTGATGCGCATCTCCGAAGCCGATATGGAC
AAATAA

Upstream 100 bases:

>100_bases
CAGCGAGCGTCCCCCGCGACGCCGAGGTGACAGCGGGGTGGCGCAAGGGGCGTGCCTGGGGTGACAATGGTGGTCTTGTT
AGTCACTTAAAAGACAGGCC

Downstream 100 bases:

>100_bases
GCACATGAGCAATTTCGACCATTTTGTAGGCACCCGGGCCGTTTCCGGGCAGCAGGCTTTTGACATCGACGTCCTCAGCA
CCTATCTGAAACAGCACCTC

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MDDPILTIDERAAINSGRWFSSLSPSLRHDILRCAYVKRYKDGELIAARGDPPEEWIACAKGAVRVSSTSLSGKQITLTY
VEPGIWFGDVAIFDGDRRTHDAYAHGDTTILCVAKADFRKILAAHVELYEAMLRLHARRLRQLFGLVEDLNTLPLRARLA
KQLLHLVRCYGVPSLADGQEIRIGLQLAQEELAQLLGASRQRVNQELKSMEREEAIRIEPGGLVVRNREALMRISEADMD
K

Sequences:

>Translated_241_residues
MDDPILTIDERAAINSGRWFSSLSPSLRHDILRCAYVKRYKDGELIAARGDPPEEWIACAKGAVRVSSTSLSGKQITLTY
VEPGIWFGDVAIFDGDRRTHDAYAHGDTTILCVAKADFRKILAAHVELYEAMLRLHARRLRQLFGLVEDLNTLPLRARLA
KQLLHLVRCYGVPSLADGQEIRIGLQLAQEELAQLLGASRQRVNQELKSMEREEAIRIEPGGLVVRNREALMRISEADMD
K
>Mature_241_residues
MDDPILTIDERAAINSGRWFSSLSPSLRHDILRCAYVKRYKDGELIAARGDPPEEWIACAKGAVRVSSTSLSGKQITLTY
VEPGIWFGDVAIFDGDRRTHDAYAHGDTTILCVAKADFRKILAAHVELYEAMLRLHARRLRQLFGLVEDLNTLPLRARLA
KQLLHLVRCYGVPSLADGQEIRIGLQLAQEELAQLLGASRQRVNQELKSMEREEAIRIEPGGLVVRNREALMRISEADMD
K

Specific function: Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=202, Percent_Identity=24.7524752475248, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR022299
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27103; Mature: 27103

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDPILTIDERAAINSGRWFSSLSPSLRHDILRCAYVKRYKDGELIAARGDPPEEWIACA
CCCCCEEECCCHHCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHC
KGAVRVSSTSLSGKQITLTYVEPGIWFGDVAIFDGDRRTHDAYAHGDTTILCVAKADFRK
CCCEEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEHHHHHH
ILAAHVELYEAMLRLHARRLRQLFGLVEDLNTLPLRARLAKQLLHLVRCYGVPSLADGQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCH
IRIGLQLAQEELAQLLGASRQRVNQELKSMEREEAIRIEPGGLVVRNREALMRISEADMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEECHHHHHHHHHCCCC
K
C
>Mature Secondary Structure
MDDPILTIDERAAINSGRWFSSLSPSLRHDILRCAYVKRYKDGELIAARGDPPEEWIACA
CCCCCEEECCCHHCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHC
KGAVRVSSTSLSGKQITLTYVEPGIWFGDVAIFDGDRRTHDAYAHGDTTILCVAKADFRK
CCCEEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEHHHHHH
ILAAHVELYEAMLRLHARRLRQLFGLVEDLNTLPLRARLAKQLLHLVRCYGVPSLADGQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCH
IRIGLQLAQEELAQLLGASRQRVNQELKSMEREEAIRIEPGGLVVRNREALMRISEADMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEECHHHHHHHHHCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1630321 [H]