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The map label for this gene is ubiE [H]

Identifier: 91788720

GI number: 91788720

Start: 3014223

End: 3015086

Strand: Direct

Name: ubiE [H]

Synonym: Bpro_2859

Alternate gene names: 91788720

Gene position: 3014223-3015086 (Clockwise)

Preceding gene: 91788719

Following gene: 91788727

Centisome position: 57.96

GC content: 61.57

Gene sequence:

>864_bases
ATGAGCACACTGAACCCGGAACAGTTCAAGACAGCTACCAGGCAAGCTTGGGACAAGTCTGCCAGCGGGTGGAACGATCA
AACACAGCATATCCATGACTGGCTCGCCGAGGCAACCCCGGCCATGCTCGATGCGGCCCGCATCACAGTCGGTATGCGGG
TACTGGACATCGCCGCAGGCGCAGGGGACCAGACGCTGGACATCGCCCGGCGGGTTGGGCCCGGTGGTTATGTGCTGGCC
ACCGACATTTCCGCAGGAATTTTGGAATTCGCAAAAAACAATGCGCGCCATGCCGGCTTGCTGAACGTGGAGACCAGCGT
CTGCGATGCCGAAAATCTGGATGTCGATGCTGCGAGCTTCGATGCTGCCGTGTCCCGGCTCGGCCTCATGTTCTGCCCAA
ACCCCTTGCTGGCGCTGCAGCAGGCTCACCGCGCCCTGAAACCCGGCGGGAGTGCATCGGTACTGGTGTTCTCGGAGCCG
CAATACAACCCCTGCATCGGCATCCTGATGTCAACGGCACTCAAGCATGCAGGCCTGCCGCCGCGCGATCCCTACCAACC
AGGAAGCTTGATGAGCCTGGGCAAGCCGGGCCTGCTTGATGAGTTGTTCCTCGCTGCGGGATTTACAGACGTGGCAACCA
CCCGGGTCTCCGCGCCCTTCCGCCTGCCCTCGACGCGGGATTATTTGACTTTCATCCGCACTTCGGCGTCACCGATCGTG
CAGATTCTGGGCAACCTGAACCAGGAAGCGCAGGACGCCGCTTGGGCGGAGATGGAAAGCAGGCTTGGTGCATTTCAGTC
ACCAGGCGGCTGGGAAGGGCCAAATGAGCTGCTGGTGGCCCGTGGAACCCGGCTGTCCAGTTGA

Upstream 100 bases:

>100_bases
GCGCATTGGAGCTGCGCATTGAGGTGTCAGAGGGATCGCTTGCGTTTGCACCTGTTTGGAATCAAACTGCCTACGGTGCG
ATTTTCCCAAGGGATACTTC

Downstream 100 bases:

>100_bases
TCTGTCGGCCAGCTCGGGATAGACGTAAAAAAGCCGCCCGAAGGCGGCTTTTTGTACTGGCGGAAACGGAGGGATTCGAA
CCCTCGATGAGGCTCTACAC

Product: UbiE/COQ5 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MSTLNPEQFKTATRQAWDKSASGWNDQTQHIHDWLAEATPAMLDAARITVGMRVLDIAAGAGDQTLDIARRVGPGGYVLA
TDISAGILEFAKNNARHAGLLNVETSVCDAENLDVDAASFDAAVSRLGLMFCPNPLLALQQAHRALKPGGSASVLVFSEP
QYNPCIGILMSTALKHAGLPPRDPYQPGSLMSLGKPGLLDELFLAAGFTDVATTRVSAPFRLPSTRDYLTFIRTSASPIV
QILGNLNQEAQDAAWAEMESRLGAFQSPGGWEGPNELLVARGTRLSS

Sequences:

>Translated_287_residues
MSTLNPEQFKTATRQAWDKSASGWNDQTQHIHDWLAEATPAMLDAARITVGMRVLDIAAGAGDQTLDIARRVGPGGYVLA
TDISAGILEFAKNNARHAGLLNVETSVCDAENLDVDAASFDAAVSRLGLMFCPNPLLALQQAHRALKPGGSASVLVFSEP
QYNPCIGILMSTALKHAGLPPRDPYQPGSLMSLGKPGLLDELFLAAGFTDVATTRVSAPFRLPSTRDYLTFIRTSASPIV
QILGNLNQEAQDAAWAEMESRLGAFQSPGGWEGPNELLVARGTRLSS
>Mature_286_residues
STLNPEQFKTATRQAWDKSASGWNDQTQHIHDWLAEATPAMLDAARITVGMRVLDIAAGAGDQTLDIARRVGPGGYVLAT
DISAGILEFAKNNARHAGLLNVETSVCDAENLDVDAASFDAAVSRLGLMFCPNPLLALQQAHRALKPGGSASVLVFSEPQ
YNPCIGILMSTALKHAGLPPRDPYQPGSLMSLGKPGLLDELFLAAGFTDVATTRVSAPFRLPSTRDYLTFIRTSASPIVQ
ILGNLNQEAQDAAWAEMESRLGAFQSPGGWEGPNELLVARGTRLSS

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=123, Percent_Identity=35.7723577235772, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30599; Mature: 30468

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLNPEQFKTATRQAWDKSASGWNDQTQHIHDWLAEATPAMLDAARITVGMRVLDIAAG
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCC
AGDQTLDIARRVGPGGYVLATDISAGILEFAKNNARHAGLLNVETSVCDAENLDVDAASF
CCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCCCEEECCHHHCCCCCCCCCHHHH
DAAVSRLGLMFCPNPLLALQQAHRALKPGGSASVLVFSEPQYNPCIGILMSTALKHAGLP
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
PRDPYQPGSLMSLGKPGLLDELFLAAGFTDVATTRVSAPFRLPSTRDYLTFIRTSASPIV
CCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHH
QILGNLNQEAQDAAWAEMESRLGAFQSPGGWEGPNELLVARGTRLSS
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
STLNPEQFKTATRQAWDKSASGWNDQTQHIHDWLAEATPAMLDAARITVGMRVLDIAAG
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCC
AGDQTLDIARRVGPGGYVLATDISAGILEFAKNNARHAGLLNVETSVCDAENLDVDAASF
CCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCCCEEECCHHHCCCCCCCCCHHHH
DAAVSRLGLMFCPNPLLALQQAHRALKPGGSASVLVFSEPQYNPCIGILMSTALKHAGLP
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
PRDPYQPGSLMSLGKPGLLDELFLAAGFTDVATTRVSAPFRLPSTRDYLTFIRTSASPIV
CCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHH
QILGNLNQEAQDAAWAEMESRLGAFQSPGGWEGPNELLVARGTRLSS
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA