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The map label for this gene is frr

Identifier: 91788554

GI number: 91788554

Start: 2833558

End: 2834118

Strand: Reverse

Name: frr

Synonym: Bpro_2692

Alternate gene names: 91788554

Gene position: 2834118-2833558 (Counterclockwise)

Preceding gene: 91788555

Following gene: 91788553

Centisome position: 54.5

GC content: 56.68

Gene sequence:

>561_bases
ATGAGCATTGTTGAAGTGAAGCAGAATGCAGAGCAAAAAATGCAGCAGTCGGTGGATTCGTTTAAAAACAGCCTGACGAA
AATCCGTACCGGCCGCGCCAACCCTGGCTTGCTGGACACCGTTCACGTGGACTACTACGGCTCCATGGTGCCCATCAGCC
AGGTGGCCAATGTGTCTCTGCTGGATGCCCGCACCATCAGCGTTTCGCCATGGGAAAAAGGCATGGGCGCCAAAATCGAA
AAGGCCATCCGCGACTCAGACCTCGGGCTCAACCCCGCGGCCCAAGGTGACCTGATTCGCGTCCCGATGCCTGCCATGAC
CGAAGAGCGCCGCAAGGAACTCACCAAAGTCGTCAGGGCAGAGGGCGAGCATGCCAAAGTGGCCGTTCGCAACTTGCGCC
GGGATGCCAATGAGGGCGTCAAGAAGCTGCTCAAGGAAAAATTGGTTTCAGAGGATGACGAGCGCCGTGCGCAGGATGAA
ATCCAGAAGTTCACGGACCGTTTCATTGCCGAGGTTGACAAACTGGTCGCCGGCAAGGAACAAGACATCATGGCGGTTTG
A

Upstream 100 bases:

>100_bases
CGAAGGAACCCTGGTTCACGTTTGATTCCGGCTCCCCGGCCATCGGCCGTGTTTTCATATTTCTTGGACTTTTTGCAGAT
AACAATCCGGAGATTCGACC

Downstream 100 bases:

>100_bases
CGCCATCCCGTCTGGCCTGAACTGACCATGGCCACTCCCTCTCTCATCGTCCCGCATCATGTGGCCATCGTGATGGATGG
CAATGGCCGCTGGGCGACCA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSIVEVKQNAEQKMQQSVDSFKNSLTKIRTGRANPGLLDTVHVDYYGSMVPISQVANVSLLDARTISVSPWEKGMGAKIE
KAIRDSDLGLNPAAQGDLIRVPMPAMTEERRKELTKVVRAEGEHAKVAVRNLRRDANEGVKKLLKEKLVSEDDERRAQDE
IQKFTDRFIAEVDKLVAGKEQDIMAV

Sequences:

>Translated_186_residues
MSIVEVKQNAEQKMQQSVDSFKNSLTKIRTGRANPGLLDTVHVDYYGSMVPISQVANVSLLDARTISVSPWEKGMGAKIE
KAIRDSDLGLNPAAQGDLIRVPMPAMTEERRKELTKVVRAEGEHAKVAVRNLRRDANEGVKKLLKEKLVSEDDERRAQDE
IQKFTDRFIAEVDKLVAGKEQDIMAV
>Mature_185_residues
SIVEVKQNAEQKMQQSVDSFKNSLTKIRTGRANPGLLDTVHVDYYGSMVPISQVANVSLLDARTISVSPWEKGMGAKIEK
AIRDSDLGLNPAAQGDLIRVPMPAMTEERRKELTKVVRAEGEHAKVAVRNLRRDANEGVKKLLKEKLVSEDDERRAQDEI
QKFTDRFIAEVDKLVAGKEQDIMAV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=175, Percent_Identity=30.2857142857143, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI291042689, Length=151, Percent_Identity=31.7880794701987, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=51.6483516483517, Blast_Score=203, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=31.25, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_POLSJ (Q12A34)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_549506.1
- ProteinModelPortal:   Q12A34
- SMR:   Q12A34
- STRING:   Q12A34
- GeneID:   4014647
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_2692
- NMPDR:   fig|296591.1.peg.410
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q12A34
- ProtClustDB:   PRK00083
- BioCyc:   PSP296591:BPRO_2692-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20786; Mature: 20655

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVEVKQNAEQKMQQSVDSFKNSLTKIRTGRANPGLLDTVHVDYYGSMVPISQVANVSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHCCHH
LDARTISVSPWEKGMGAKIEKAIRDSDLGLNPAAQGDLIRVPMPAMTEERRKELTKVVRA
HCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHC
EGEHAKVAVRNLRRDANEGVKKLLKEKLVSEDDERRAQDEIQKFTDRFIAEVDKLVAGKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QDIMAV
CCCCCC
>Mature Secondary Structure 
SIVEVKQNAEQKMQQSVDSFKNSLTKIRTGRANPGLLDTVHVDYYGSMVPISQVANVSL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHCCHH
LDARTISVSPWEKGMGAKIEKAIRDSDLGLNPAAQGDLIRVPMPAMTEERRKELTKVVRA
HCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHC
EGEHAKVAVRNLRRDANEGVKKLLKEKLVSEDDERRAQDEIQKFTDRFIAEVDKLVAGKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QDIMAV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA