Click here to switch to the map view.

The map label for this gene is pyrH [H]

Identifier: 91788555

GI number: 91788555

Start: 2834194

End: 2834904

Strand: Reverse

Name: pyrH [H]

Synonym: Bpro_2693

Alternate gene names: 91788555

Gene position: 2834904-2834194 (Counterclockwise)

Preceding gene: 91788556

Following gene: 91788554

Centisome position: 54.51

GC content: 60.2

Gene sequence:

>711_bases
ATGCCAGCCTACAAGCGGATCTTGTTAAAACTGTCAGGTGAGGCCTTGATGGGGGATGATGCCTTTGGCATCAACCACGC
CACCATCGTGCGCATGGTGGAAGAAATTGCCGAGGTCACCCGCATGGGCGTCCAGGTGGCGGTGGTGATCGGCGGCGGCA
ACATCTTCCGCGGCGTGGCGGGTGGCTCGGTCGGCATGGACCGGGCGACTGCCGACTACATGGGTATGCTGGCGACCGTG
ATGAACGCGCTGGCTCTGGGCGACACCATGGACAAGGCGGGCCTGATTGCCCGCGTCATGTCGGCCATTGGCATCGAGCG
CGTGGTCGAACCTTATGTGCGGCCCAAGGCGCTGCAGTACCTGGAAGAAGGCAAGGTCGTCATTTTCGCGGCCGGCACAG
GCAATCCTTTCTTTACGACCGACACGGCCGCTGCGCTGCGCGGTGCCGAAATCGGGGCTGAAATCGTCCTGAAGGCGACC
AAAGTCGATGGCGTGTACACGGCGGATCCGAAGAAGGATCCACGCGCAACGCGCTACACCAACATCACTTTTGATGAGGC
GATGGGCAAGAACCTCGAAGTCATGGACGCTACAGCGTTTGCCCTGTGCCGCGACCAGAAGCTGCCGATCAAGGTTTTTA
GTATTTTCAAGCACGGAGCGCTCAAACGCGTGGTGCAGGGTGAGGACGAAGGAACCCTGGTTCACGTTTGA

Upstream 100 bases:

>100_bases
AGTTGCGGCCCAGATAGCTGCAGCCAAAGCAGCCTAAGCAACTCAGCCCTGCCGGAAGGCCGCTAAACTTCAGATCAACC
CAATTACGGAGAGCCCTCAC

Downstream 100 bases:

>100_bases
TTCCGGCTCCCCGGCCATCGGCCGTGTTTTCATATTTCTTGGACTTTTTGCAGATAACAATCCGGAGATTCGACCATGAG
CATTGTTGAAGTGAAGCAGA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MPAYKRILLKLSGEALMGDDAFGINHATIVRMVEEIAEVTRMGVQVAVVIGGGNIFRGVAGGSVGMDRATADYMGMLATV
MNALALGDTMDKAGLIARVMSAIGIERVVEPYVRPKALQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEIGAEIVLKAT
KVDGVYTADPKKDPRATRYTNITFDEAMGKNLEVMDATAFALCRDQKLPIKVFSIFKHGALKRVVQGEDEGTLVHV

Sequences:

>Translated_236_residues
MPAYKRILLKLSGEALMGDDAFGINHATIVRMVEEIAEVTRMGVQVAVVIGGGNIFRGVAGGSVGMDRATADYMGMLATV
MNALALGDTMDKAGLIARVMSAIGIERVVEPYVRPKALQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEIGAEIVLKAT
KVDGVYTADPKKDPRATRYTNITFDEAMGKNLEVMDATAFALCRDQKLPIKVFSIFKHGALKRVVQGEDEGTLVHV
>Mature_235_residues
PAYKRILLKLSGEALMGDDAFGINHATIVRMVEEIAEVTRMGVQVAVVIGGGNIFRGVAGGSVGMDRATADYMGMLATVM
NALALGDTMDKAGLIARVMSAIGIERVVEPYVRPKALQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEIGAEIVLKATK
VDGVYTADPKKDPRATRYTNITFDEAMGKNLEVMDATAFALCRDQKLPIKVFSIFKHGALKRVVQGEDEGTLVHV

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=233, Percent_Identity=58.3690987124464, Blast_Score=276, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25227; Mature: 25096

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAYKRILLKLSGEALMGDDAFGINHATIVRMVEEIAEVTRMGVQVAVVIGGGNIFRGVA
CCHHHEEHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCC
GGSVGMDRATADYMGMLATVMNALALGDTMDKAGLIARVMSAIGIERVVEPYVRPKALQY
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LEEGKVVIFAAGTGNPFFTTDTAAALRGAEIGAEIVLKATKVDGVYTADPKKDPRATRYT
HHCCCEEEEEECCCCCCEECCHHHHHHHHHCCCEEEEEEEECCCEEECCCCCCCCCCEEE
NITFDEAMGKNLEVMDATAFALCRDQKLPIKVFSIFKHGALKRVVQGEDEGTLVHV
EEEHHHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEC
>Mature Secondary Structure 
PAYKRILLKLSGEALMGDDAFGINHATIVRMVEEIAEVTRMGVQVAVVIGGGNIFRGVA
CHHHEEHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCC
GGSVGMDRATADYMGMLATVMNALALGDTMDKAGLIARVMSAIGIERVVEPYVRPKALQY
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LEEGKVVIFAAGTGNPFFTTDTAAALRGAEIGAEIVLKATKVDGVYTADPKKDPRATRYT
HHCCCEEEEEECCCCCCEECCHHHHHHHHHCCCEEEEEEEECCCEEECCCCCCCCCCEEE
NITFDEAMGKNLEVMDATAFALCRDQKLPIKVFSIFKHGALKRVVQGEDEGTLVHV
EEEHHHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA