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The map label for this gene is lpxA [H]

Identifier: 91788545

GI number: 91788545

Start: 2824160

End: 2824972

Strand: Reverse

Name: lpxA [H]

Synonym: Bpro_2683

Alternate gene names: 91788545

Gene position: 2824972-2824160 (Counterclockwise)

Preceding gene: 91788546

Following gene: 91788544

Centisome position: 54.32

GC content: 61.25

Gene sequence:

>813_bases
ATGACCGCGCCAGTTCCCGCGCCGGGCATTCATGCCACCGCCCTTGTCGATCCTCTGGCCCAGCTGGACAGCTCGGTCAG
TGTCGGCCCTTACACGGTTATCGGTCCCCATGTCAGGGTGGGGGCAGGCACCACCATCGGGGCCCATTGCGTGATCGAGG
GCCACACAACGATAGGTCGCGACAACCGGATTTTCCAGTTCAACTCGCTCGGTGCGATTCCGCAGGACAAAAAATACGCG
GGCGAACCCTGCGAACTGGTCATTGGCGACCGCAACACCATCCGCGAGTTCTGTACTTTCAATATCGGCTCACCGGGTGA
CAGCGGTGTGACAAGCGTGGGCGATGACAACTGGATCATGGCTTATGTGCATCTGGCGCATGACTGTGTGGTGGGTAACC
ACACGATCTTCGCCAACAACTCCCAGCTGGCCGGTCACGTTTATGTGGGCGACTGGGTCATTCTGGGCGGTTTTACCGTG
GCGCACCAATTTGTCCGGCTGGGCGCCCACAGCATGACGGCCATGTGTTCGCTGCTGTTTGCCGATTTGCCGCCGTTCGT
CATGGCACAAGGCCAGCCCGCGCAGGCGCGGTCGATGAATTTTGAGGGCCTGCGGCGCCGCGGCTTTTCTGCCGGACGCC
TTTCGGCCGTCAAGGCCATGCACAAGGCGCTGTACCGGGATGATTTGACACTGGATCTGGCCCGGGCTCGAATCGCTGAA
CTGGCCGACAAGCAGCCGGAAGCGGCTCCCGATATCCAGATGATGCTGTCATTCCTGGCGCAAACCTCGCCGCAGCGCGG
CATTGTCCGGTAG

Upstream 100 bases:

>100_bases
TTCAAATTCAAGGGTGTGACGCGCGTGGGTGAGGCCATCGCCTGCGAGGCCGAGTTGATGTGCACCATGCGCACCATTGC
CTGAAGGTGGCTTGAAAGAC

Downstream 100 bases:

>100_bases
CCGGCCTCCATGAGCGCGGCACCCAGGATCGCCATGGTTGCCGGAGAAACTTCCGGTGATTTGCTGGCTGGCTTGCTGCT
GGACGGGCTGCGTGAGCGCT

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTAPVPAPGIHATALVDPLAQLDSSVSVGPYTVIGPHVRVGAGTTIGAHCVIEGHTTIGRDNRIFQFNSLGAIPQDKKYA
GEPCELVIGDRNTIREFCTFNIGSPGDSGVTSVGDDNWIMAYVHLAHDCVVGNHTIFANNSQLAGHVYVGDWVILGGFTV
AHQFVRLGAHSMTAMCSLLFADLPPFVMAQGQPAQARSMNFEGLRRRGFSAGRLSAVKAMHKALYRDDLTLDLARARIAE
LADKQPEAAPDIQMMLSFLAQTSPQRGIVR

Sequences:

>Translated_270_residues
MTAPVPAPGIHATALVDPLAQLDSSVSVGPYTVIGPHVRVGAGTTIGAHCVIEGHTTIGRDNRIFQFNSLGAIPQDKKYA
GEPCELVIGDRNTIREFCTFNIGSPGDSGVTSVGDDNWIMAYVHLAHDCVVGNHTIFANNSQLAGHVYVGDWVILGGFTV
AHQFVRLGAHSMTAMCSLLFADLPPFVMAQGQPAQARSMNFEGLRRRGFSAGRLSAVKAMHKALYRDDLTLDLARARIAE
LADKQPEAAPDIQMMLSFLAQTSPQRGIVR
>Mature_269_residues
TAPVPAPGIHATALVDPLAQLDSSVSVGPYTVIGPHVRVGAGTTIGAHCVIEGHTTIGRDNRIFQFNSLGAIPQDKKYAG
EPCELVIGDRNTIREFCTFNIGSPGDSGVTSVGDDNWIMAYVHLAHDCVVGNHTIFANNSQLAGHVYVGDWVILGGFTVA
HQFVRLGAHSMTAMCSLLFADLPPFVMAQGQPAQARSMNFEGLRRRGFSAGRLSAVKAMHKALYRDDLTLDLARARIAEL
ADKQPEAAPDIQMMLSFLAQTSPQRGIVR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=261, Percent_Identity=46.7432950191571, Blast_Score=254, Evalue=4e-69,
Organism=Escherichia coli, GI1786376, Length=247, Percent_Identity=24.6963562753036, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28961; Mature: 28830

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPVPAPGIHATALVDPLAQLDSSVSVGPYTVIGPHVRVGAGTTIGAHCVIEGHTTIGR
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCEEEECCCCEECEEEEEECCCEECC
DNRIFQFNSLGAIPQDKKYAGEPCELVIGDRNTIREFCTFNIGSPGDSGVTSVGDDNWIM
CCEEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHEECCCCCCCCCCCCCCCCCEEE
AYVHLAHDCVVGNHTIFANNSQLAGHVYVGDWVILGGFTVAHQFVRLGAHSMTAMCSLLF
EEEEHHHHEEECCEEEEECCCCEEEEEEECCEEEECCHHHHHHHHHHCHHHHHHHHHHHH
ADLPPFVMAQGQPAQARSMNFEGLRRRGFSAGRLSAVKAMHKALYRDDLTLDLARARIAE
HCCCHHHEECCCCCHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LADKQPEAAPDIQMMLSFLAQTSPQRGIVR
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TAPVPAPGIHATALVDPLAQLDSSVSVGPYTVIGPHVRVGAGTTIGAHCVIEGHTTIGR
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCEEEECCCCEECEEEEEECCCEECC
DNRIFQFNSLGAIPQDKKYAGEPCELVIGDRNTIREFCTFNIGSPGDSGVTSVGDDNWIM
CCEEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHEECCCCCCCCCCCCCCCCCEEE
AYVHLAHDCVVGNHTIFANNSQLAGHVYVGDWVILGGFTVAHQFVRLGAHSMTAMCSLLF
EEEEHHHHEEECCEEEEECCCCEEEEEEECCEEEECCHHHHHHHHHHCHHHHHHHHHHHH
ADLPPFVMAQGQPAQARSMNFEGLRRRGFSAGRLSAVKAMHKALYRDDLTLDLARARIAE
HCCCHHHEECCCCCHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LADKQPEAAPDIQMMLSFLAQTSPQRGIVR
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA