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The map label for this gene is lpxB [H]

Identifier: 91788544

GI number: 91788544

Start: 2822996

End: 2824126

Strand: Reverse

Name: lpxB [H]

Synonym: Bpro_2682

Alternate gene names: 91788544

Gene position: 2824126-2822996 (Counterclockwise)

Preceding gene: 91788545

Following gene: 91788543

Centisome position: 54.31

GC content: 59.95

Gene sequence:

>1131_bases
ATGGTTGCCGGAGAAACTTCCGGTGATTTGCTGGCTGGCTTGCTGCTGGACGGGCTGCGTGAGCGCTGGCCGGGCTTGCA
GACCTGCGGTATTGGCGGGCCGTACATGGCCGGGCGCGGTTTTCAGGCCTGGTGGCCGCACGACAAGCTGGCGGTACGCG
GCTATGTGGAGGTGCTGCGTCATTACCGTGAGATCGTCGGCATACGCGAGCAACTGAAAAAGCGGCTGCTCGATCAGCGC
CCTGATATTTTCATCGGTGTAGACGCCCCCGACTTCAATCTCGACCTCGAAGCGGCTCTGAAGGCGCAGGGCATCAAGAC
CGTCCATTTTGTCAGTCCTTCCGTCTGGGCCTGGCGTGCGAACCGCGTCGAGAAGATCCGGCGCAGCGTAGACCACGTGC
TGTGCATTTTTCCGTTCGAACCAGCCTTGCTGGCTTCCCATGGCATTGCGGCCACGTATGTCGGCCATCCGCTGGCCAGC
GTGATTCCCCTGCAGCCGGACCGGGCCGCCGCGAGGCGCAAGTTGGGACTGCAGGATGACGCCGTGGTCATCGCGATCTT
GCCGGGTAGCCGCAAGTCCGAGATCCAATATTTGGCCGAGAGGTTTTTCAGGGCTGCAGCCTTGGTAAAACGAGCACAAC
CGGCTATCAAATTTATAGTTCCAGCCGTCCCTTTGCTGAAAACCGTGATCGAGCGACTGGCCGATGCGGCCGGCATGCGG
GCCGACCTGCAAATTATCGAAGGCCAGTCGCACACCGCGCTCGCTGCTTGCGATGTGACCCTGATTGCCAGCGGCACCGC
GACCCTGGAAGCGGCTTTGTTCAAGCGCCCCATGGTGATTGCCTACAACATGAACTGGCTGTCGTGGCAGATCATGCGGC
GCAAGAAGCTGCAGCCCTGGGTTGGACTGCCCAATATCCTGTGCCAGGATTTCGTTGTGCCCGAGCTGCTGCAGGAAGCG
GCGACGCCAGAAGCGTTGGCTGCCGGGTTGTTGCAATGGGTGGATGCAAAATCAACGGCTCCTGCCAAAATAGCGGCTGT
TGAACAACGATTCATGGCGCTGCATGCCGAACTGCAGCGCGATACTTCTCAATTGGCGACCGATGCGATCCAGCAAATTC
TTGAAAGCTGA

Upstream 100 bases:

>100_bases
TCCCGATATCCAGATGATGCTGTCATTCCTGGCGCAAACCTCGCCGCAGCGCGGCATTGTCCGGTAGCCGGCCTCCATGA
GCGCGGCACCCAGGATCGCC

Downstream 100 bases:

>100_bases
GCAAACTCCCTTGTCCTGGGACACTCCCGGTCTCCTGGCCGGCGTGGACGAGGCCGGGCGGGGCCCGCTGATGGGCCCAG
TGGTGGCTGCGGCTGTCATC

Product: lipid-A-disaccharide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MVAGETSGDLLAGLLLDGLRERWPGLQTCGIGGPYMAGRGFQAWWPHDKLAVRGYVEVLRHYREIVGIREQLKKRLLDQR
PDIFIGVDAPDFNLDLEAALKAQGIKTVHFVSPSVWAWRANRVEKIRRSVDHVLCIFPFEPALLASHGIAATYVGHPLAS
VIPLQPDRAAARRKLGLQDDAVVIAILPGSRKSEIQYLAERFFRAAALVKRAQPAIKFIVPAVPLLKTVIERLADAAGMR
ADLQIIEGQSHTALAACDVTLIASGTATLEAALFKRPMVIAYNMNWLSWQIMRRKKLQPWVGLPNILCQDFVVPELLQEA
ATPEALAAGLLQWVDAKSTAPAKIAAVEQRFMALHAELQRDTSQLATDAIQQILES

Sequences:

>Translated_376_residues
MVAGETSGDLLAGLLLDGLRERWPGLQTCGIGGPYMAGRGFQAWWPHDKLAVRGYVEVLRHYREIVGIREQLKKRLLDQR
PDIFIGVDAPDFNLDLEAALKAQGIKTVHFVSPSVWAWRANRVEKIRRSVDHVLCIFPFEPALLASHGIAATYVGHPLAS
VIPLQPDRAAARRKLGLQDDAVVIAILPGSRKSEIQYLAERFFRAAALVKRAQPAIKFIVPAVPLLKTVIERLADAAGMR
ADLQIIEGQSHTALAACDVTLIASGTATLEAALFKRPMVIAYNMNWLSWQIMRRKKLQPWVGLPNILCQDFVVPELLQEA
ATPEALAAGLLQWVDAKSTAPAKIAAVEQRFMALHAELQRDTSQLATDAIQQILES
>Mature_376_residues
MVAGETSGDLLAGLLLDGLRERWPGLQTCGIGGPYMAGRGFQAWWPHDKLAVRGYVEVLRHYREIVGIREQLKKRLLDQR
PDIFIGVDAPDFNLDLEAALKAQGIKTVHFVSPSVWAWRANRVEKIRRSVDHVLCIFPFEPALLASHGIAATYVGHPLAS
VIPLQPDRAAARRKLGLQDDAVVIAILPGSRKSEIQYLAERFFRAAALVKRAQPAIKFIVPAVPLLKTVIERLADAAGMR
ADLQIIEGQSHTALAACDVTLIASGTATLEAALFKRPMVIAYNMNWLSWQIMRRKKLQPWVGLPNILCQDFVVPELLQEA
ATPEALAAGLLQWVDAKSTAPAKIAAVEQRFMALHAELQRDTSQLATDAIQQILES

Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG0763

COG function: function code M; Lipid A disaccharide synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxB family [H]

Homologues:

Organism=Escherichia coli, GI1786379, Length=374, Percent_Identity=40.1069518716578, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003835 [H]

Pfam domain/function: PF02684 LpxB [H]

EC number: =2.4.1.182 [H]

Molecular weight: Translated: 41471; Mature: 41471

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAGETSGDLLAGLLLDGLRERWPGLQTCGIGGPYMAGRGFQAWWPHDKLAVRGYVEVLR
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
HYREIVGIREQLKKRLLDQRPDIFIGVDAPDFNLDLEAALKAQGIKTVHFVSPSVWAWRA
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHH
NRVEKIRRSVDHVLCIFPFEPALLASHGIAATYVGHPLASVIPLQPDRAAARRKLGLQDD
HHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHCCCHHHHCCCCCCHHHHHHHCCCCCC
AVVIAILPGSRKSEIQYLAERFFRAAALVKRAQPAIKFIVPAVPLLKTVIERLADAAGMR
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ADLQIIEGQSHTALAACDVTLIASGTATLEAALFKRPMVIAYNMNWLSWQIMRRKKLQPW
CCEEEECCCCCCEEEEECEEEEECCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCC
VGLPNILCQDFVVPELLQEAATPEALAAGLLQWVDAKSTAPAKIAAVEQRFMALHAELQR
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DTSQLATDAIQQILES
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVAGETSGDLLAGLLLDGLRERWPGLQTCGIGGPYMAGRGFQAWWPHDKLAVRGYVEVLR
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
HYREIVGIREQLKKRLLDQRPDIFIGVDAPDFNLDLEAALKAQGIKTVHFVSPSVWAWRA
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHH
NRVEKIRRSVDHVLCIFPFEPALLASHGIAATYVGHPLASVIPLQPDRAAARRKLGLQDD
HHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHCCCHHHHCCCCCCHHHHHHHCCCCCC
AVVIAILPGSRKSEIQYLAERFFRAAALVKRAQPAIKFIVPAVPLLKTVIERLADAAGMR
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ADLQIIEGQSHTALAACDVTLIASGTATLEAALFKRPMVIAYNMNWLSWQIMRRKKLQPW
CCEEEECCCCCCEEEEECEEEEECCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCC
VGLPNILCQDFVVPELLQEAATPEALAAGLLQWVDAKSTAPAKIAAVEQRFMALHAELQR
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DTSQLATDAIQQILES
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA