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The map label for this gene is ndk [H]

Identifier: 91788474

GI number: 91788474

Start: 2742921

End: 2743346

Strand: Reverse

Name: ndk [H]

Synonym: Bpro_2612

Alternate gene names: 91788474

Gene position: 2743346-2742921 (Counterclockwise)

Preceding gene: 91788475

Following gene: 91788473

Centisome position: 52.75

GC content: 56.34

Gene sequence:

>426_bases
ATGGCGATCGAACGCACTCTCTCCATCATCAAGCCCGACGCAGTTGCAAAAAACGTCATTGGCCAGATTTATGCACGTTT
TGAGGCCGCCGGCCTGAAAGTCGTGGCGGCCAAAATGGCTCACCTTTCAAAGGGCGAGGCTGAGGCTTTCTACGCGGTGC
ACAAGGAGCGTCCCTTCTTCAAGGACCTCGTGTCGTTCATGATTTCCGGTCCCGTCATGATCCAGGCGCTGGAAGGCGAG
GGCGCCATTCTGAAGAACCGCGACCTGATGGGCGCGACCGATCCGAAGAAGGCTGCAGCCGGCACGATTCGCGCCGATTT
TGCTGACAGCATTGATGCCAATGCCGTCCATGGTTCGGATGCCGTCGAAACTGCCCAGGCGGAAATTGCATTCTTCTTCC
CGGGCATGAATATTTACTCGCGTTAA

Upstream 100 bases:

>100_bases
TACTTCACAGGGTTGATTCGAACAGATCAGCCCACAGGTTAAAATCAGAGGCTGTATTCAGTTTCTGAATCATTTAAAAA
TCCAAGGTTAAGGAAAATTC

Downstream 100 bases:

>100_bases
TCATGCTGCCCCCCATGCGTTGCTACTCCCCGCCAGGGTCGTCGCTTGCCTGGGGCGGTCCAGCCTGTCGCCCTCTGCAA
TGACAGCCAACCTTCTTGAC

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MAIERTLSIIKPDAVAKNVIGQIYARFEAAGLKVVAAKMAHLSKGEAEAFYAVHKERPFFKDLVSFMISGPVMIQALEGE
GAILKNRDLMGATDPKKAAAGTIRADFADSIDANAVHGSDAVETAQAEIAFFFPGMNIYSR

Sequences:

>Translated_141_residues
MAIERTLSIIKPDAVAKNVIGQIYARFEAAGLKVVAAKMAHLSKGEAEAFYAVHKERPFFKDLVSFMISGPVMIQALEGE
GAILKNRDLMGATDPKKAAAGTIRADFADSIDANAVHGSDAVETAQAEIAFFFPGMNIYSR
>Mature_140_residues
AIERTLSIIKPDAVAKNVIGQIYARFEAAGLKVVAAKMAHLSKGEAEAFYAVHKERPFFKDLVSFMISGPVMIQALEGEG
AILKNRDLMGATDPKKAAAGTIRADFADSIDANAVHGSDAVETAQAEIAFFFPGMNIYSR

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=132, Percent_Identity=43.9393939393939, Blast_Score=119, Evalue=6e-28,
Organism=Homo sapiens, GI66392227, Length=131, Percent_Identity=40.4580152671756, Blast_Score=113, Evalue=4e-26,
Organism=Homo sapiens, GI66392205, Length=131, Percent_Identity=40.4580152671756, Blast_Score=113, Evalue=4e-26,
Organism=Homo sapiens, GI4505409, Length=131, Percent_Identity=40.4580152671756, Blast_Score=113, Evalue=4e-26,
Organism=Homo sapiens, GI66392192, Length=131, Percent_Identity=40.4580152671756, Blast_Score=113, Evalue=4e-26,
Organism=Homo sapiens, GI66392203, Length=131, Percent_Identity=40.4580152671756, Blast_Score=113, Evalue=4e-26,
Organism=Homo sapiens, GI38045913, Length=131, Percent_Identity=40.4580152671756, Blast_Score=113, Evalue=7e-26,
Organism=Homo sapiens, GI4557797, Length=131, Percent_Identity=40.4580152671756, Blast_Score=112, Evalue=8e-26,
Organism=Homo sapiens, GI4826862, Length=130, Percent_Identity=39.2307692307692, Blast_Score=106, Evalue=6e-24,
Organism=Homo sapiens, GI7019465, Length=134, Percent_Identity=35.8208955223881, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI37574614, Length=134, Percent_Identity=35.8208955223881, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI5031951, Length=137, Percent_Identity=36.4963503649635, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI30023828, Length=138, Percent_Identity=32.6086956521739, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI4505413, Length=136, Percent_Identity=33.0882352941176, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788866, Length=133, Percent_Identity=62.406015037594, Blast_Score=179, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI17506807, Length=130, Percent_Identity=44.6153846153846, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322783, Length=130, Percent_Identity=42.3076923076923, Blast_Score=119, Evalue=2e-28,
Organism=Drosophila melanogaster, GI45549037, Length=130, Percent_Identity=45.3846153846154, Blast_Score=122, Evalue=8e-29,
Organism=Drosophila melanogaster, GI18860097, Length=135, Percent_Identity=34.8148148148148, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 15134; Mature: 15002

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIERTLSIIKPDAVAKNVIGQIYARFEAAGLKVVAAKMAHLSKGEAEAFYAVHKERPFF
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHH
KDLVSFMISGPVMIQALEGEGAILKNRDLMGATDPKKAAAGTIRADFADSIDANAVHGSD
HHHHHHHHCCCEEEEEECCCCCEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
AVETAQAEIAFFFPGMNIYSR
HHHHHHHEEEEEECCCHHCCC
>Mature Secondary Structure 
AIERTLSIIKPDAVAKNVIGQIYARFEAAGLKVVAAKMAHLSKGEAEAFYAVHKERPFF
CCHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHH
KDLVSFMISGPVMIQALEGEGAILKNRDLMGATDPKKAAAGTIRADFADSIDANAVHGSD
HHHHHHHHCCCEEEEEECCCCCEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
AVETAQAEIAFFFPGMNIYSR
HHHHHHHEEEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA